What Makes Companies to Survive over a Century? The Case of Dongwha Pharmaceutical in the Republic of Korea

Considering their significant impacts on national economy, local communities, employees, suppliers, and other stakeholders, firm survival is an important goal for most companies. However, firm longevity is not an easy result to achieve, and it becomes more difficult as business environments shift dramatically. The average life span of companies listed in Standard and Poor’s 500 was 61 years in 1958, but it fell to less than 18 years in 2016. Nevertheless, more than 3000 companies over 200 years old still operate in Japan, mostly family inherited small and medium enterprises (SMEs), and Germany has many centenarian companies, especially in the manufacturing industry. However, in the Republic of Korea, with over 4000 years of history, there are no companies older than 200 years and only seven companies with over 100 years of history. Centenarian companies in Korea are very limited, and even after surviving over 100 years, they continue to face severe challenges they need to overcome in order to survive. However, it is not clearly proven what factors affect the survival of companies for over a century. Since SMEs contribute to the economic development and survival of a country, it is important to investigate the secrets of their longevity, which has become even more difficult than ever. However, as there is very limited research on firm longevity, the findings from this case study of Dongwha Pharmaceutical, balancing the continuity of tradition and innovation, provide significant implications and practical guidelines for Korean SMEs for their survival and sustainable management, which is an economic and business aspect of sustainability.

Geometric imperfect preventive maintenance and replacement (GIPMAR) model for aging repairable systems

PurposeThis work seeks to develop a geometric imperfect preventive maintenance (PM) and replacement model (GIPMAR) for aging repairable systems due to age and prolong usage that would meet users need in three phases: within average life span, beyond average life span and beyond initial replacement age of system.Design/methodology/approachThe authors utilized the geometric process (GP) as the hazard function to characterize the increasing failure rate (IFR) of the system. The GP hazard function was incorporated into the hybridized preventive and replacement model of Lin et al. (2000). The resultant expected cost rate function was optimized to obtain optimum intervals for PM/replacement and required numbers of PM per cycle. The proposed GIPMAR model was applied to repairable systems characterized by Weibull life function and the results yielded PM/replacement schedules for three different phases of system operation.FindingsThe proposed GIPMAR model is a generalization of Lin et al. (2000) PM model that were comparable with results of earlier models and is adaptive to situations in developing countries where systems are used across the three phases of operation depicted in this work. This may be due to economic hardship and operating environment.Practical implicationsThe proposed model has provided PM/Replacement schedules for different phases of operation which was never considered. This would provide a useful guide to maintenance engineers and end-users in developing countries with a view to minimizing the average cost of maintenance as well as reducing the number of down times of systems.Social implicationsA duly implemented GIPMAR model would ensure efficient operation of systems, optimum man-hour need in the organization and guarantee customer's goodwill in a competitive environment.Originality/valueIn this work, the authors have extended Lin et al. (2000) PM model to provide PM/replacement schedules for aging repairable systems which was not provided for in earlier existing models and literature.

Impact of war on veteran life span: natural experiment involving combat versus non-combat exposed military personnel

IntroductionThere is still uncertainty around the impact of combat exposure on the life span of war veterans. Therefore we made use of a natural experiment to study the impact on veteran life span of combat versus non-combat exposure in World War II (WW2).MethodsThe combat-exposed military personnel were derived from a random (10%) sample of the military roll of the 28th (Māori) Battalion from New Zealand. One non-combat cohort was the 15th Reinforcements of this same Battalion, since the war ended before they reached the front line. The other non-combat cohort were Māori personnel who were only involved in Jayforce, which occupied Japan at the end of the WW2. Data on life span were mainly derived from an official repository of birth and death records, but supplemented with other sources, including military files.ResultsWhen comparing life spans of service veterans, there was no statistically significant reduction for the average life span of the 234 combat-exposed veterans in our sample from the 28th (Māori) Battalion (66.7 years), relative to the Māori veterans from two non-combat cohorts: the 132 personnel in the 15th Reinforcements (67.2 years) and the 147 personnel in Jayforce (66.9 years).ConclusionsDespite a very high level of wounding in the combat-exposed group (48%), there were no statistically significant reductions in life span between this group and comparable non-combat exposed veterans. This finding contrasts to life span reductions found in a similar study of New Zealand veterans of WW1.

Study of Forest Land Function Transfer and its Role in Labour Absorption, Economic Growth and Increase in Human Development Index in West Kalimantan

Timber forests have many functions and play an essential role in human life. This means that the existence of timber forests provides many benefits for human life. Economic development activities actively implemented throughout the province of West Kalimantan have resulted in more and more areas of timber forest and rubber plantation areas being converted into oil palm plantations. The rampant development of oil palm plantations carried out by investors and those carried out independently by each resident, in essence, provides a significant enough job opportunity for the population in each area that continues to grow. Job opportunities created through economic development offer opportunities to every working population to earn income, fulfilling various life needs is mainly directed to fulfilling family nutritional consumption. If the family's nutrition is guaranteed, then the average life span of the population can be longer. In addition to meeting his family's needs, this income can also be used to finance children's education belonging to the school-age group. If the income earned by each family is large enough, then the family should be able to live in prosperity. This means that timber forest and rubber plantation areas privately owned by the community have been converted into oil palm plantations, significantly contributing to the economic growth of districts/cities in West Kalimantan province and improving the community's welfare.

Outcomes of Dialysis in low Income Country – An Experience in a Tertiary Care Center of Bangladesh

Background: The widespread use of hemodialysis to prolong life of end-stage renal disease (ESRD) patients has been a remarkable achievement, preventing death from uremia in these patients. The aim of the study was to find out the outcomes of haemodialysis patients with end-stage renal disease (ESRD) in low Income County. Methods: A hospital based prospective observational study was performed in the of Department of Nephrology, Shaheed Suhrawardy Medical College. Total 189 patients who stated dialysis during study period were included. All patients were monthly followed up and appropriate investigation done. All data recorded in a case record form. Study protocol approved by Ethical committeeof institute. Data analyzed in SPSS software version 25. Results: Among 189 ESRD patients on MHD selected with mean age 49.16 years (15-82), male was 60.3% and female 39.7%.Eighty eight 46.5% patient died and 39.15%(74) patient discontinue dialysis due to lack of financial support or helping assistant or social support. Three (1.6%) patients underwent renal transplantation and five patients (2.6%) transfer to other dialysis center. Average life span in dialysis 256 day (16-786 days). Most of the paints was on twice weekly dialysis 84%. Vascular access of stating dialysis was 73.8% by catheter and only 32.2% stated with AV fistula. Conclusion: A large group of patients leave dialysis due to financial or helping personal or social supportwithin 3-4 months of stating dialysis. A significant number of patients died due to multiple risk factors within 8-9 months. Identification of risk factors for early mortalityis essential and appropriatemeasure should take to prevent discontinuation at community and national level. Bangladesh J Medicine July 2022; 33(1) : 52-56

Molecular Characterization of Rotifers and Their Potential Use in the Biological Control of Biomphalaria

BackgroundSchistosomiasis is one of the most important tropical parasitic diseases worldwide. Biomphalaria straminea, the intermediate host of Schistosoma mansoni, has invaded and spread to Southern China since 1974 and may pose enormous threats to public health. Controlling intermediate host snails is an effective strategy in schistosomiasis intervention. However, the only effective chemical molluscicide, niclosamide, currently recommended by WHO may cause environmental pollution, loss of biodiversity, and high costs. Thus, to counter intermediate hosts, a sustainable and environmentally friendly tool is urgently needed. Here, we conducted field investigations to collect and identify a potential snail competitor rotifer and evaluated its molluscicide effect.ResultsIn this study, we collected two samples of rotifers from Shenzhen. We found both red and black phenotypic B. straminea snails at the sampling sites. We identified the rotifer population as a species of the genus Philodina according to the amplification and phylogenetic analysis results of coxI gene. We found that rotifer exposure did not significantly affect the hatching rate of B. straminea eggs but promoted the killing of juvenile snails. Meanwhile, rotifer exposure did not significantly alter the fecundity of B. straminea quantified by the number of eggs per egg mass, the number of egg masses per snail, and the number of eggs per snail; but the snails exposed to rotifers showed lower fecundity performance than the control snails. Importantly, rotifer exposure could significantly affect the development of juvenile B. straminea, showing a smaller shell diameter of the exposed snails than that of the control snails. In addition, rotifer exposure affected the life span of B. straminea snails, showing a 16.61% decline in the average life span. After rotifer exposure, the S. mansoni-infected B. straminea snails died significantly faster than those without rotifer exposure. Similar findings were observed in S. mansoni-infected Biomphalaria glabrata snails. These results implied that rotifer exposure significantly promoted the mortality of S. mansoni-infected B. straminea and B. glabrata.ConclusionsOur study demonstrated the potential molluscicide effect of rotifers on intermediate hosts under laboratory conditions. Our findings may provide new insights into the development of biocontrol strategies for snail-borne disease transmission.

Phytoplankton Time-Series in a LTER Site of the Adriatic Sea: Methodological Approach to Decipher Community Structure and Indicative Taxa

In the shallow and landlocked northeast Adriatic Sea, environmental factors have changed in recent decades. Their influence on seasonal and inter-annual variability of phytoplankton has been documented in the recent literature. Here, we decipher the long-term variability of phytoplankton phenology at a Long-Term Ecological Research site (Gulf of Trieste, Slovenia). Structural changes in the phytoplankton community (period 2005–2017) were analysed using a multivariate protocol based on Bayesian clustering. The protocol was modified from the literature to fit the needs of the study, using correspondence analysis and k-means clustering. A novel index for ordination and selection of taxa based on frequency and evenness was developed. The Total Inertia analysis showed that this index better preserved the available information. Typical seasonal assemblages were highlighted by applying the Indicative Value index in conjunction with likelihood ratio values. We obtained a rough picture of the seasonal separation of the diatom-dominated community from the mixed community and a refined picture of the phenology of the assemblages and bloom events. The spring diatom peak proved to be inconstant and short-lived, while the autumn bloom was generally long and diverse. As expected for nearshore environments, the average life span of the assemblages was found to be short-periodic (2–4 months). The second part of the year and the last part of the series were more prone to changes in terms of typical assemblages.

Lower Kolyma multilingualism: Historical setting and sociolinguistic trends

Aims and objectives/purpose/research questions: The region of Lower Kolyma (LK), Russia, exhibits a unique multilingual situation which involves five languages from five different families: Even (Tungusic), Yakut (Turkic), Chukchi (Chukotko-Kamchatkan), Tundra Yukaghir (Yukaghir), and Russian (Slavic, Indo-European). Our research aims to show the ongoing changes in this setting and to explain the historical background of these trends. Design/methodology/approach: Our approach combines the results of a sociolinguistic survey, published data about the history and ethnography of the region, and observed linguistic effects of language contact. Data and analysis: The sample for our sociolinguistic study includes 196 individuals, born between 1878 and 1996. To assess the patterns of multilingualism we use two parameters: the number of acquired languages and the composition of the linguistic repertoires. To model the linguistic situation in the 20th century, an average life span parameter is used. Findings/conclusions: We demonstrate that in 1940 to 1980 it was most common for LK residents to use all languages of the region. Partly, at least, this was a consequence of the introduction of boarding schools, which became an additional domain for interethnic communication. In recent decades we observe a tendency for a shift to Russian with a concomitant decrease in speakers of the minority languages. Originality: We use an approach of retrospective interviews which allows us to cover a large time period and to provide an overview of changes in the multilingual setting during the 20th century. Thus, even though multilingualism in this area has already been discussed by Vakhtin, the methodological approach is different. Significance/implications: The paper contributes to the field of sociolinguistics, presenting a new case study of multilingualism from an area of Siberia which is understudied in this regard.

Hearing Outcomes and Complications of Cochlear Implantation in Elderly Patients over 75 Years of Age

Objective: Populations are aging in many countries, and the proportion of elderly people with severe to profound hearing loss is increasing in parallel with the increasing average life span. The objective of this study was to investigate the outcomes of cochlear implant (CI) surgery in elderly patients compared to those in younger patients. Methods: The outcomes of CI surgery were retrospectively investigated for 81 adults (32 men and 49 women) who underwent CI surgery at our hospital. They were divided according to age at the time of implantation into the younger group (<75 years of age; n = 49) or elderly group (≥75 years of age; n = 32). Results: The mean sentence recognition score on the CI-2004 Japanese open-set test battery (±standard deviation) was 82.9% ± 24.1 in the younger group and 81.9% ± 23.2 in the elderly group, with no significant difference between the groups (Mann–Whitney U test). The incidence of major complications that required surgical treatment was not significantly different between the groups (4.1% vs. 6.2%, respectively). Thus, there were no severe complications that could affect general health status in either group. Three patients in each group died for reasons unrelated to CI surgery during follow-up. The proportion of patients who were alive and continued to use the CI five years after surgery was 92.8% and 91.5%, respectively. Conclusion: Our results show good speech recognition and a low incidence of major complications in elderly patients. This comprehensive report on the outcomes of CI surgery in elderly patients will be helpful to the elderly with severe to profound hearing loss when deciding whether to undergo CI surgery.