scholarly journals Case Report: Repeated Transcranial Magnetic Stimulation Improves Comorbid Binge Eating Disorder in Two Female Patients With Treatment-Resistant Bipolar Depression

2021 ◽  
Vol 12 ◽  
Author(s):  
Domenico Sciortino ◽  
Giandomenico Schiena ◽  
Filippo Cantù ◽  
Eleonora Maggioni ◽  
Paolo Brambilla

Introduction: Binge eating disorder (BED) is the most common eating disorder, affecting a large population worldwide. It is characterized by recurrent episodes of binge eating, with no compensatory behaviors. BED is often associated with psychiatric comorbidities, and still represents a challenge in terms of treatment strategies. In the last years, neuromodulation has represented a promising approach in the treatment of BED. We report the cases of two women, affected by Bipolar Disorder Type II (BD-II) and comorbid BED, whose BED symptoms improved after a course of accelerated intermittent Theta Burst Stimulation (iTBS).Methods: We carried out a clinical study, involving neurostimulation on six patients with a treatment-resistant depressive episode. The trial consisted of a 3-week accelerated iTBS treatment, delivered to the left dorsolateral pre-frontal cortex. Clinical evaluation scales (Hamilton Rating Scale for Depression, Montgomery-Åsberg Depression Rating Scale, and Young Mania Rating Scale) were administered at baseline, after 2 weeks, and at the end of the stimulation cycle. Pharmacotherapy was maintained unchanged during iTBS treatment. Patients gave their informed consent both for the protocol and for the publication.Results: The treatment was well-tolerated. Depressive symptoms only slightly improved; however, patients' binge episodes remitted completely, which was a serendipitous finding. BED symptomatology complete remission lasted up to 12 weeks follow-up.Discussion: This is the first study regarding iTBS use in BED in comorbidity with BD-II. Further research is still needed to assess the efficacy of this technique in BED treatment.

2001 ◽  
Vol 10 (2) ◽  
pp. 95-116
Author(s):  
K. Jason Crandall ◽  
Patricia A. Eisenman

Binge eating disorder (BED) is a relatively new eating disorder that involves recurrent binge eating without compensatory purging behaviors such as using laxatives, excessive physical activity, and/or dietary restraint. Individuals diagnosed with BED exhibit both psychological and physiological problems that are distinct from bulimia nervosa and non-BED obese individuals. There has been little to no research examining the effects of physical activity on BED treatment. Since current BED treatment strategies have been less than successful, physical activity may be a positive addition to BED treatment. Therefore the objectives of this paper are 1) to raise the awareness of exercise professionals as to. the existence of BED, 2) explore the mechanisms that might support the utilization of physical activity as an adjunct treatment strategy for BED and 3) to prompt more interest among researchers and practitioners relative to using physical activity interventions with BED clients.


2011 ◽  
Vol 59 (4) ◽  
pp. 267-274 ◽  
Author(s):  
Anja Hilbert

Zusammenfassung.Die Klassifikation von Essstörungen steht im Zentrum aktuellen Forschungsinteresses. Gerade relativ rezente diagnostische Kategorien wie die Binge-Eating- oder Essanfallsstörung (Binge Eating Disorder, BED) und diagnostische Hauptmerkmale wie Essanfälle bedürfen im Zuge der Überarbeitungen des DSM einer Überprüfung. In dem vorliegenden Artikel werden zunächst die für das DSM-V vorgeschlagenen Veränderungen der diagnostischen Kriterien der BED und anderer Essstörungen beschrieben. An­schließend wird das Essanfallsmerkmal der Größe der verzehrten Nahrungsmenge in einer Forschungsübersicht hinsichtlich seiner klinischen Relevanz für die BED betrachtet. Dabei zeigt sich, dass sowohl objektive als auch subjektive Essanfälle psychopathologisch relevant sind. Jedoch sind objektive Essanfälle aufgrund ihrer Assoziation mit einem geringeren Behandlungserfolg, einer größeren residualen Symptomatik und vermehrten Rückfalltendenzen das vergleichsweise stringentere Erfolgskriterium in der Therapieerfolgsforschung der BED. Vor diesem Hintergrund erscheint es für die BED zentral, neben objektiven Essanfällen zusätzlich auch subjektive Essanfälle zu erfassen. Für das DSM-V wird empfohlen, ein Schema zu entwerfen, um das Auftreten und die Häufigkeit dieser Formen von Essanfällen für die BED sowie für andere klinische und subklinische Formen von Essanfällen systematisch zu erheben. Eine sorgfältige Erfassung der Essanfallsgröße in Studien zur Psychopathologie, zum Verlauf und zur Behandlung, wird es erlauben, die klinische Relevanz dieses Merkmals über das Essstörungsspektrum hinweg weiter zu klären.


2018 ◽  
Vol 127 (6) ◽  
pp. 548-558 ◽  
Author(s):  
Eva Naumann ◽  
Jennifer Svaldi ◽  
Tanja Wyschka ◽  
Markus Heinrichs ◽  
Bernadette von Dawans

2002 ◽  
Author(s):  
D. E. Wilfley ◽  
R. R. Welch ◽  
R. I. Stein ◽  
E .B. Spurrell ◽  
L. R. Cohen ◽  
...  

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