scholarly journals A New Era of Neuro-Oncology Research Pioneered by Multi-Omics Analysis and Machine Learning

Biomolecules ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 565
Author(s):  
Satoshi Takahashi ◽  
Masamichi Takahashi ◽  
Shota Tanaka ◽  
Shunsaku Takayanagi ◽  
Hirokazu Takami ◽  
...  

Although the incidence of central nervous system (CNS) cancers is not high, it significantly reduces a patient’s quality of life and results in high mortality rates. A low incidence also means a low number of cases, which in turn means a low amount of information. To compensate, researchers have tried to increase the amount of information available from a single test using high-throughput technologies. This approach, referred to as single-omics analysis, has only been partially successful as one type of data may not be able to appropriately describe all the characteristics of a tumor. It is presently unclear what type of data can describe a particular clinical situation. One way to solve this problem is to use multi-omics data. When using many types of data, a selected data type or a combination of them may effectively resolve a clinical question. Hence, we conducted a comprehensive survey of papers in the field of neuro-oncology that used multi-omics data for analysis and found that most of the papers utilized machine learning techniques. This fact shows that it is useful to utilize machine learning techniques in multi-omics analysis. In this review, we discuss the current status of multi-omics analysis in the field of neuro-oncology and the importance of using machine learning techniques.

2021 ◽  
Author(s):  
Fabian Fernando Jurado Lasso ◽  
Letizia Marchegiani ◽  
Jesus Fabian Jurado ◽  
Adnan Abu Mahfouz ◽  
Xenofon Fafoutis

This paper is aimed to present a comprehensive survey of relevant research over the period 2012-2021 of Software-Defined Wireless Sensor Network (SDWSN) proposals and Machine Learning (ML) techniques to perform network management, policy enforcement, and network configuration functions. This survey provides helpful information and insights to the scientific and industrial communities, and professional organisations interested in SDWSNs, mainly the current state-of-art, machine learning techniques, and open issues.


2019 ◽  
Vol 20 (3) ◽  
pp. 185-193 ◽  
Author(s):  
Natalie Stephenson ◽  
Emily Shane ◽  
Jessica Chase ◽  
Jason Rowland ◽  
David Ries ◽  
...  

Background:Drug discovery, which is the process of discovering new candidate medications, is very important for pharmaceutical industries. At its current stage, discovering new drugs is still a very expensive and time-consuming process, requiring Phases I, II and III for clinical trials. Recently, machine learning techniques in Artificial Intelligence (AI), especially the deep learning techniques which allow a computational model to generate multiple layers, have been widely applied and achieved state-of-the-art performance in different fields, such as speech recognition, image classification, bioinformatics, etc. One very important application of these AI techniques is in the field of drug discovery.Methods:We did a large-scale literature search on existing scientific websites (e.g, ScienceDirect, Arxiv) and startup companies to understand current status of machine learning techniques in drug discovery.Results:Our experiments demonstrated that there are different patterns in machine learning fields and drug discovery fields. For example, keywords like prediction, brain, discovery, and treatment are usually in drug discovery fields. Also, the total number of papers published in drug discovery fields with machine learning techniques is increasing every year.Conclusion:The main focus of this survey is to understand the current status of machine learning techniques in the drug discovery field within both academic and industrial settings, and discuss its potential future applications. Several interesting patterns for machine learning techniques in drug discovery fields are discussed in this survey.


Author(s):  
Daniel Kudenko ◽  
Dimitar Kazakov ◽  
Eduardo Alonso

In order to be truly autonomous, agents need the ability to learn from and adapt to the environment and other agents. This chapter introduces key concepts of machine learning and how they apply to agent and multi-agent systems. Rather than present a comprehensive survey, we discuss a number of issues that we believe are important in the design of learning agents and multi-agent systems. Specifically, we focus on the challenges involved in adapting (originally disembodied) machine learning techniques to situated agents, the relationship between learning and communication, learning to collaborate and compete, learning of roles, evolution and natural selection, and distributed learning. In the second part of the chapter, we focus on some practicalities and present two case studies.


Author(s):  
Daniel Kudenko ◽  
Dimitar Kazakov ◽  
Eduardo Alonso

In order to be truly autonomous, agents need the ability to learn from and adapt to the environment and other agents. This chapter introduces key concepts of machine learning and how they apply to agent and multi-agent systems. Rather than present a comprehensive survey, we discuss a number of issues that we believe are important in the design of learning agents and multi-agent systems. Specifically, we focus on the challenges involved in adapting (originally disembodied) machine learning techniques to situated agents, the relationship between learning and communication, learning to collaborate and compete, learning of roles, evolution and natural selection, and distributed learning. In the second part of the chapter, we focus on some practicalities and present two case studies.


2019 ◽  
pp. 1-4
Author(s):  
Lavanya Vemulapalli

Machine Learning plays a significant role among the areas of Artificial Intelligence (AI). During recent years, Machine Learning (ML) has been attracting many researchers, and it has been successfully applied in many fields such as medical, education, forecasting etc., Right now, the diagnosis of diseases is mostly from expert's decision. Diagnosis is a major task in clinical science as it is crucial in determining if a patient is having the disease or not. This in turn decides the suitable path of treatment for disease diagnosis. Applying machine learning techniques for disease diagnosis using intelligent algorithms has been a hot research area of computer science. This paper throws a light on the comprehensive survey on the machine learning applications in the medical disease prognosis during the past decades


2020 ◽  
Vol 10 (4) ◽  
pp. 1270
Author(s):  
Razvan Raducu ◽  
Gonzalo Esteban ◽  
Francisco J. Rodríguez Lera ◽  
Camino Fernández

Different Machine Learning techniques to detect software vulnerabilities have emerged in scientific and industrial scenarios. Different actors in these scenarios aim to develop algorithms for predicting security threats without requiring human intervention. However, these algorithms require data-driven engines based on the processing of huge amounts of data, known as datasets. This paper introduces the SonarCloud Vulnerable Code Prospector for C (SVCP4C). This tool aims to collect vulnerable source code from open source repositories linked to SonarCloud, an online tool that performs static analysis and tags the potentially vulnerable code. The tool provides a set of tagged files suitable for extracting features and creating training datasets for Machine Learning algorithms. This study presents a descriptive analysis of these files and overviews current status of C vulnerabilities, specifically buffer overflow, in the reviewed public repositories.


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