scholarly journals Physiological and Medico-Social Research Trends of the Wave P300 and More Late Components of Visual Event-Related Potentials

2021 ◽  
Vol 11 (1) ◽  
pp. 125
Author(s):  
Sergey Lytaev ◽  
Irina Vatamaniuk
Keyword(s):  
Sensory System ◽  
Interaction Model ◽  
Event Related Potentials ◽  
Peak Latency ◽  
Visual Images ◽  
Time Interval ◽  
Brain Pathology ◽  
Bmdp Statistical Software ◽  
Related Potentials ◽  
Sensory Processes

To extend the application of the late waves of the event-related potentials (ERPs) to multiple modalities, devices and software the underlying physiological mechanisms and responses of the brain for a particular sensory system and mental function must be carefully examined. The objective of this study was aimed to study the sensory processes of the “human-computer interaction” model when classifying visual images with an incomplete set of signs based on the analysis of early, middle, late and slow ERPs components. 26 healthy subjects (men) aged 20–26 years were investigated. ERPs in 19 monopolar sites according to the 10/20 system were recorded. Discriminant and factor analyzes (BMDP Statistical Software) were applied. The component N450 is the most specialized indicator of the perception of unrecognizable (oddball) visual images. The amplitude of the ultra-late components N750 and N900 is also higher under conditions of presentation of the oddball image, regardless of the location of the registration points. In brain pathology along with the pronounced asymmetry of the wave distribution, reduction of the N150 wave and lengthening of its peak latency, a line of regularities were noted. These include–a pronounced reduction in peak latency P250 and N350, an increased amplitude of N350 in the frontal and central points of registration, a decrease in the amplitude of N450 in the left frontal cortex and its increase in the occipital registration points, activation of the occipital cortex at a time interval of 400–500 ms, as well as fusion later waves. We called such phenomena of the development of cognitive ERP in brain pathology “the incongruence of ERP components”. The results of the research are discussed in the light of the paradigm of the P300 wave application in brain-computer interface systems, as well as with the peculiarities in brain pathology.

scholarly journals Physiological and Medico-Social Research Trends of the Wave P300 and More Late Components of Visual Event-Related Potentials

2020 ◽  
Author(s):  
Sergey Lytaev ◽  
Irina Vatamaniuk
Keyword(s):  
Social Research ◽  
Brain Computer Interface ◽  
Sensory System ◽  
Event Related Potentials ◽  
Computer Interface ◽  
Visual Images ◽  
Physiological Mechanisms ◽  
Multiple Modalities ◽  
Related Potentials ◽  
Sensory Processes

The objective of this study was aimed to study the sensory processes of the “human-computer interaction” model when classifying visual images with an incomplete set of signs based on the analysis of early, middle, late and slow components of event-related potentials (ERPs). 26 healthy subjects (men) aged 20-22 years were investigated. ERPs in 19 monopolar sites according to the 10/20 system were recorded. Discriminant and factor analysis were applied. The component N450 is the most specialized indicator of the perception of unrecognizable (oddball) visual images. The amplitude of the ultra-late components N750 and N900 is also higher under conditions of presentation of the oddball image, regardless of the location of the registration points. The results of the study are discussed in the light of the paradigm of the P300 wave application in brain-computer interface systems, as well as with the peculiarities in brain pathology. Promising directions for the development of studies of the “Brain Computer Interface” (BCI) P300 systems are to increase the throughput of information flows. To extend the application of the P300 ERPs to multiple modalities, the underlying physiological mechanisms and responses of the brain for a particular sensory system and mental function must be carefully examined.

scholarly journals Modality differences in ERP components between somatosensory and auditory Go/No-go paradigms in prepubescent children

PLoS ONE ◽  
2021 ◽  
Vol 16 (11) ◽  
pp. e0259653
Author(s):  
Hiroki Nakata ◽  
Miho Takezawa ◽  
Keita Kamijo ◽  
Manabu Shibasaki
Keyword(s):  
Reaction Time ◽  
Behavioral Responses ◽  
Event Related Potentials ◽  
Error Rates ◽  
Peak Latency ◽  
Peak Amplitude ◽  
Time Variability ◽  
Commission Error ◽  
Reaction Time Variability ◽  
Related Potentials

We investigated modality differences in the N2 and P3 components of event-related potentials (ERPs) between somatosensory and auditory Go/No-go paradigms in eighteen healthy prepubescent children (mean age: 125.9±4.2 months). We also evaluated the relationship between behavioral responses (reaction time, reaction time variability, and omission and commission error rates) and amplitudes and latencies of N2 and P3 during somatosensory and auditory Go/No-go paradigms. The peak latency of No-go-N2 was significantly shorter than that of Go-N2 during somatosensory paradigms, but not during auditory paradigms. The peak amplitude of P3 was significantly larger during somatosensory than auditory paradigms, and the peak latency of P3 was significantly shorter during somatosensory than auditory paradigms. Correlations between behavioral responses and the P3 component were not found during somatosensory paradigms. On the other hand, in auditory paradigms, correlations were detected between the reaction time and peak amplitude of No-go-P3, and between the reaction time variability and peak latency of No-go-P3. A correlation was noted between commission error and the peak latency of No-go-N2 during somatosensory paradigms. Compared with previous adult studies using both somatosensory and auditory Go/No-go paradigms, the relationships between behavioral responses and ERP components would be weak in prepubescent children. Our data provide findings to advance understanding of the neural development of motor execution and inhibition processing, that is dependent on or independent of the stimulus modality.

scholarly journals Cortical Auditory Disorders: A Case of Non-Verbal Disturbances Assessed with Event-Related Brain Potentials

1998 ◽  
Vol 11 (1) ◽  
pp. 55-73 ◽  
Author(s):  
Sönke Johannes ◽  
Michael E. Jöbges ◽  
Reinhard Dengler ◽  
Thomas F. Münte
Keyword(s):  
Current Knowledge ◽  
Hemispheric Specialization ◽  
Sensory Information ◽  
Event Related Potentials ◽  
Absolute Pitch ◽  
Oddball Paradigm ◽  
Auditory Modality ◽  
Related Potentials ◽  
Sensory Processes ◽  
Auditory Disorders

In the auditory modality, there has been a considerable debate about some aspects of cortical disorders, especially about auditory forms of agnosia. Agnosia refers to an impaired comprehension of sensory information in the absence of deficits in primary sensory processes. In the non-verbal domain, sound agnosia and amusia have been reported but are frequently accompanied by language deficits whereas pure deficits are rare. Absolute pitch and musicians’ musical abilities have been associated with left hemispheric functions. We report the case of a right handed sound engineer with the absolute pitch who developed sound agnosia and amusia in the absence of verbal deficits after a right perisylvian stroke. His disabilities were assessed with the Seashore Test of Musical Functions, the tests of Wertheim and Botez (Wertheim and Botez, Brain 84, 1961, 19–30) and by event-related potentials (ERP) recorded in a modified 'oddball paradigm’. Auditory ERP revealed a dissociation between the amplitudes of the P3a and P3b subcomponents with the P3b being reduced in amplitude while the P3a was undisturbed. This is interpreted as reflecting disturbances in target detection processes as indexed by the P3b. The findings that contradict some aspects of current knowledge about left/right hemispheric specialization in musical processing are discussed and related to the literature concerning cortical auditory disorders.

Difference in Areas of the Brain for Fuzzy and Crisp Calculation

2002 ◽  
Vol 6 (1) ◽  
pp. 51-55 ◽  
Author(s):  
Takahiro Yamanoi ◽  
◽  
Masaaki Saito ◽  
Michio Sugeno ◽  
EIie Sanchez ◽  
...  
Keyword(s):  
Right Hemisphere ◽  
Event Related Potentials ◽  
Type A ◽  
Peak Latency ◽  
Dipole Source ◽  
Type B ◽  
Current Dipole ◽  
Significant Difference ◽  
Related Potentials ◽  
The Right

We recorded event-related potentials (ERPs) by electroencephalography (EEG) during fuzzy and crisp calculation. Questions art divided into 2 types. As type A, questions were presented as sentences. Questions of type B were presented as numerical calculation. In type A, the peak latency of the EEG was around 1100ms. In type B, the peak latency was around 650ms. In type A, from multiple equivalent current dipole source localization (ECDL) around the latency, it followed that sources during fuzzy calculation lie in the right hemisphere and that sources during crisp calculation lie in the left hemisphere. In type B, no significant difference was observed.

Combining CDP-choline and galantamine: Effects of a selective α7 nicotinic acetylcholine receptor agonist strategy on P50 sensory gating of speech sounds in healthy volunteers

2019 ◽  
Vol 33 (6) ◽  
pp. 688-699 ◽  
Author(s):  
Joelle Choueiry ◽  
Crystal M Blais ◽  
Dhrasti Shah ◽  
Dylan Smith ◽  
Derek Fisher ◽  
...  
Keyword(s):  
Pilot Study ◽  
Acetylcholine Receptor ◽  
Nicotinic Acetylcholine Receptor ◽  
Event Related Potentials ◽  
Sensory Gating ◽  
Nicotinic Acetylcholine ◽  
Healthy Humans ◽  
Α7 Nachr ◽  
Related Potentials ◽  
Sensory Processes

Background: Schizophrenia (SCZ) patients and relatives have deficits in early cortical sensory gating (SG) typically measured by suppression of electroencephalography-derived P50 event-related potentials (ERPs) in a conditioning-testing (S1–S2) paradigm. Associated with alpha 7 nicotinic acetylcholine receptor (α7 nAChR) dysfunction and shown to be improved with nicotine and α7 nAChR agonists, SG has recently been shown to be improved in low P50 suppressing SCZ patients following acute CDP-choline treatment. Aims: This pilot study in healthy humans assessed the SG effects of an α7 nAChR strategy combining CDP-choline with galantamine, a positive allosteric modulator (PAM) of nAChRs, aimed at increasing and prolonging nicotinic receptor activity. Methods: The combined effect of CDP-choline (500 mg) and galantamine (16 mg) on speech P50 gating indices rP50 (S2/S1) and dP50 (S1–S2) was examined in 30 healthy participants stratified into low and high baseline P50 suppressors in a randomized, double-blind, placebo-controlled and counterbalanced design. Results: In low suppressors, CDP-choline/galantamine (vs. placebo) improved rP50 and dP50 gating, and reduced S2P50 amplitudes. No P50 gating effects were observed in high suppressors; however, CDP-choline/galantamine (vs. placebo) increased their S2P50 amplitudes. Conclusion: Findings from this pilot study with CDP-choline/galantamine in a healthy, SCZ-like surrogate deficient gating sample are consistent with the association of α7 nAChR mechanisms in SG impairment in SCZ and support further research trials with CDP-choline and galantamine targeting sensory processes.

scholarly journals Association between categorization of emotionally-charged and neutral visual scenes and parameters of event-related potentials in carriers of COMT, HTR2A, BDNF gene polymorphisms

F1000Research ◽  
2020 ◽  
Vol 9 ◽  
pp. 446
Author(s):  
Elena V. Vorobyeva ◽  
Pavel N. Ermakov ◽  
Evgenij F. Borokhovski ◽  
Ekaterina M. Kovsh ◽  
Alexander S. Stoletniy
Keyword(s):  
Gene Polymorphisms ◽  
Event Related Potentials ◽  
Visual Images ◽  
Bdnf Gene ◽  
Heterozygous Genotype ◽  
Related Potentials ◽  
Unpaired Student ◽  
Visual Scenes ◽  
Study Participants ◽  
Electroencephalogram Eeg

Background: This study aimed to discover the association between parameters of event-related potentials (ERPs) and categorization of images of visual scenes, both emotionally-charged and neutral, in carriers of polymorphisms of the COMT, HTR2A, BDNF genes. Methods: Electroencephalogram (EEG) and ERPs were recorded at 128 leads, with two ear referents. Images of different visual scenes were presented to the study participants sequentially on a monitor screen. The participants’ task was to examine these images and indicate what emotions (negative, neutral or positive) they elicit. Comparison of event-related potentials was carried out using unpaired Student t-test in EEGLAB toolbox. Results: COMT. A stronger reaction, as reflected in the amplitude of the ERPs, in participants with the recessive homozygous Met/Met genotype was observed on latency around 200 ms to the stimuli, assessed as positive. Carriers of dominant homozygous Val/Val genotype had higher amplitude of 200 ms peak when assessed scene images as either neutral or negative in comparison to other genotypes. Participant with the Val/Met heterozygous genotype had higher amplitude of ERP that Met/Met group on same latency when assessed stimuli as negative. HTR2A. Significant increase in negativity in the parietal-occipital regions revealed in the range of 350-420 ms in participants with the recessive homozygous A/A genotype when choosing any type of assessment, compared to carriers of the heterozygous genotype A/G and the dominant homozygous G/G genotype. BDNF. Participants with Val/Val genotype categorized the visual images more thoroughly, as reflected in greater activation of the parietal-occipital zones and higher amplitude on ERP peak on 190 ms (negative assessment) and 160 ms (neutral assessment) then Val/Met carriers. Conclusions: The COMT, HTR2A, BDNF gene polymorphisms are associated with the process of categorizing emotionally charged and neutral visual scenes, and this relationship is reflected in the ERP parameters.

Face Context Influences Local Part Processing: An ERP Study

Perception ◽  
2017 ◽  
Vol 46 (9) ◽  
pp. 1090-1104 ◽  
Author(s):  
Hong Zhang ◽  
Yaoru Sun ◽  
Lun Zhao
Keyword(s):  
Face Perception ◽  
Face Processing ◽  
Context Effect ◽  
Early Stage ◽  
Event Related Potentials ◽  
Peak Latency ◽  
Oddball Paradigm ◽  
Local Part ◽  
Configural Information ◽  
Related Potentials

Perception of face parts on the basis of features is thought to be different from perception of whole faces, which is more based on configural information. Face context is also suggested to play an important role in face processing. To investigate how face context influences the early-stage perception of facial local parts, we used an oddball paradigm that tested perceptual stages of face processing rather than recognition. We recorded the event-related potentials (ERPs) elicited by whole faces and face parts presented in four conditions (upright-normal, upright-thatcherised, inverted-normal and inverted-thatcherised), as well as the ERPs elicited by non-face objects (whole houses and house parts) with corresponding conditions. The results showed that face context significantly affected the N170 with increased amplitudes and earlier peak latency for upright normal faces. Removing face context delayed the P1 latency but did not affect the P1 amplitude prominently for both upright and inverted normal faces. Across all conditions, neither the N170 nor the P1 was modulated by house context. The significant changes on the N170 and P1 components revealed that face context influences local part processing at the early stage of face processing and this context effect might be specific for face perception. We further suggested that perceptions of whole faces and face parts are functionally distinguished.

scholarly journals Experiential avoidance and aversive visual images: Response delays and event-related potentials on a simple matching task

2007 ◽  
Vol 45 (6) ◽  
pp. 1379-1388 ◽  
Author(s):  
Andy Cochrane ◽  
Dermot Barnes-Holmes ◽  
Yvonne Barnes-Holmes ◽  
Ian Stewart ◽  
Carmen Luciano
Keyword(s):  
Experiential Avoidance ◽  
Event Related Potentials ◽  
Matching Task ◽  
Visual Images ◽  
Related Potentials

scholarly journals Association between categorization of emotionally-charged and neutral visual scenes and parameters of event-related potentials in carriers of different COMT, HTR2A, BDNF gene genotypes

F1000Research ◽  
2020 ◽  
Vol 9 ◽  
pp. 446
Author(s):  
Elena V. Vorobyeva ◽  
Pavel N. Ermakov ◽  
Evgenij F. Borokhovski ◽  
Ekaterina M. Kovsh ◽  
Alexander S. Stoletniy
Keyword(s):  
Event Related Potentials ◽  
Visual Images ◽  
Bdnf Gene ◽  
Heterozygous Genotype ◽  
Related Potentials ◽  
Unpaired Student ◽  
Visual Scenes ◽  
Study Participants ◽  
Electroencephalogram Eeg ◽  
Genotype A

Background: This study aimed to discover the association between parameters of event-related potentials (ERPs) and categorization of images of visual scenes, both emotionally-charged and neutral, in carriers of different genotypes of the COMT, HTR2A, BDNF genes. Methods: Electroencephalogram (EEG) and ERPs were recorded at 128 leads, with two ear referents. Images of different visual scenes were presented to the study participants sequentially on a monitor screen. The participants’ task was to examine these images and indicate what emotions (negative, neutral or positive) they elicit. Comparison of event-related potentials was carried out using unpaired Student t-test in EEGLAB toolbox. Results: COMT. A stronger reaction, as reflected in the amplitude of the ERPs, in participants with the recessive homozygous Met/Met genotype was observed on latency around 200 ms to the stimuli, assessed as positive. Carriers of dominant homozygous Val/Val genotype had higher amplitude of 200 ms peak when assessed scene images as either neutral or negative in comparison to other genotypes. Participant with the Val/Met heterozygous genotype had higher amplitude of ERP that Met/Met group on same latency when assessed stimuli as negative. HTR2A. Significant increase in negativity in the parietal-occipital regions revealed in the range of 350-420 ms in participants with the recessive homozygous A/A genotype when choosing any type of assessment, compared to carriers of the heterozygous genotype A/G and the dominant homozygous G/G genotype. BDNF. Participants with Val/Val genotype categorized the visual images more thoroughly, as reflected in greater activation of the parietal-occipital zones and higher amplitude on ERP peak on 190 ms (negative assessment) and 160 ms (neutral assessment) then Val/Met carriers. Conclusions: The COMT, HTR2A, BDNF gene different genotypes are associated with the process of categorizing emotionally charged and neutral visual scenes, and this relationship is reflected in the ERP parameters.

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