Primary Central Nervous System Lymphoma in Elderly Patients: Management and Perspectives
Keyword(s):
The management of elderly patients suffering from primary central nervous system (CNS) lymphoma, who represent a rapidly growing population, is challenging. Despite the advances made in PCNSL treatment, the prognosis in older patients remains unsatisfactory. The high risk of systemic and CNS toxicity induced by a high-dose chemotherapy regimen and radiation therapy, respectively, limits the use of consolidation phase treatments in elderly patients and contributes to the poor outcome of these patients. Here, we review the current treatment strategies and ongoing trials proposed for elderly PCNSL patients.
2020 ◽
Vol 38
(15_suppl)
◽
pp. 2562-2562
2012 ◽
Vol 47
(10)
◽
pp. 1383-1384
◽
Challenges in the Treatment of Newly Diagnosed and Recurrent Primary Central Nervous System Lymphoma
2020 ◽
Vol 18
(11)
◽
pp. 1571-1578
2020 ◽
2019 ◽
Vol 7
◽
pp. 232470961989354