scholarly journals Randomized Longitudinal Study Comparing Three Nasal Respiratory Support Modes to Prevent Intermittent Hypoxia in Very Preterm Infants

Children ◽  
2020 ◽  
Vol 7 (10) ◽  
pp. 168
Author(s):  
Maximilian Gross ◽  
Anette Poets ◽  
Renate Steinfeldt ◽  
Michael S. Urschitz ◽  
Katrin Böckmann ◽  
...  
Keyword(s):  
Sample Size ◽  
Preterm Infants ◽  
Intermittent Hypoxia ◽  
Positive Pressure Ventilation ◽  
Small Sample Size ◽  
Intermittent Positive Pressure Ventilation ◽  
Small Sample ◽  
Positive Pressure ◽  
Very Preterm Infants ◽  
Very Preterm

Nasal continuous positive airway pressure (NCPAP) devices using variable (vf-) and continuous (cf-) flow or synchronized nasal intermittent positive pressure ventilation (s-NIPPV) are used to prevent or treat intermittent hypoxia (IH) in preterm infants. Results concerning which is most effective vary. We aimed to investigate the effect of s-NIPPV and vf-NCPAP compared to cf-NCPAP on the rate of IH episodes. Preterm infants with a gestational age of 24.9–29.7 weeks presenting with IH while being treated with cf-NCPAP were monitored for eight hours, then randomized to eight hours of treatment with vf-NCPAP or s-NIPPV. Data from 16 infants were analyzed. Due to an unexpectedly low sample size, the results were only reported descriptively. No relevant changes in the rate of IH events were detected between cf- vs. vf-NCPAP or between cf-NCPAP vs. s-NIPPV. Although limited by its small sample size, s-NIPPV, vf- and cf-NCPAP seemed to be similarly effective in the treatment of IH in these infants.

scholarly journals Randomized Longitudinal Study Comparing 3 Nasal Respiratory Support Modes to Prevent Intermittent Hypoxia in Very Preterm Infants

2020 ◽  
Author(s):  
Maximilian Gross ◽  
Anette Poets ◽  
Renate Steinfeldt ◽  
Michael S. Urschitz ◽  
Katrin Böckmann ◽  
...  
Keyword(s):  
Sample Size ◽  
Preterm Infants ◽  
Intermittent Hypoxia ◽  
Positive Pressure Ventilation ◽  
Small Sample Size ◽  
Intermittent Positive Pressure Ventilation ◽  
Small Sample ◽  
Positive Pressure ◽  
Very Preterm Infants ◽  
Very Preterm

Abstract Background: Nasal continuous positive airway pressure (NCPAP) devices using variable (vf-) and continuous (cf-) flow or synchronized nasal intermittent positive pressure ventilation (s-NIPPV) are used to prevent or treat intermittent hypoxia (IH) in preterm infants. Results on which is most effective vary. We aimed to investigate the effect of s-NIPPV and vf-NCPAP compared to cf-NCPAP on the rate of IH episodes.Methods: Preterm infants with a gestational age of 24.9-29.7 weeks presenting with IH while being treated with cf-NCPAP were monitored for 8 hours, then randomized to 8 h of treatment with vf-NCPAP or s-NIPPV. Data from 16 infants were analyzed. Due to an unexpectedly low sample size, results are only reported descriptively.Results: No relevant changes in the rate of IH events were detected between cf- vs. vf-NCPAP or between cf-NCPAP vs. s-NIPPV.Conclusion: Although limited by its small sample size, s-NIPPV, vf- and cf-NCPAP seemed to be similarly effective in the treatment of IH in these infants.Trial registration: This study was registered with the German Clinical Trials register - DRKS00005387. Registered 12 November 2013, https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00005387

scholarly journals Hemodynamic Effects of Nasal Intermittent Positive Pressure Ventilation in Preterm Infants

Medicine ◽  
2016 ◽  
Vol 95 (6) ◽  
pp. e2780 ◽  
Author(s):  
Hung-Yang Chang ◽  
Kun-Shan Cheng ◽  
Hou-Ling Lung ◽  
Sung-Tse Li ◽  
Chien-Yu Lin ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Positive Pressure Ventilation ◽  
Intermittent Positive Pressure Ventilation ◽  
Positive Pressure ◽  
Hemodynamic Effects

scholarly journals Stereophotogrammetric head shape assessment in neonates is feasible and can identify distinct differences between term-born and very preterm infants at term equivalent age

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Petra Santander ◽  
Anja Quast ◽  
Johanna Hubbert ◽  
Laura Juenemann ◽  
Sebastian Horn ◽  
...  
Keyword(s):  
Body Weight ◽  
Preterm Infants ◽  
Total Duration ◽  
Neurodevelopmental Outcome ◽  
Small Sample ◽  
Head Shape ◽  
Term Infants ◽  
Very Preterm Infants ◽  
Equivalent Age ◽  
Very Preterm

AbstractThe development of head shape and volume may reflect neurodevelopmental outcome and therefore is of paramount importance in neonatal care. Here, we compare head morphology in 25 very preterm infants with a birth weight of below 1500 g and / or a gestational age (GA) before 32 completed weeks to 25 term infants with a GA of 37–42 weeks at term equivalent age (TEA) and identify possible risk factors for non-synostotic head shape deformities. For three-dimensional head assessments, a portable stereophotogrammetric device was used. The most common and distinct head shape deformity in preterm infants was dolichocephaly. Severity of dolichocephaly correlated with GA and body weight at TEA but not with other factors such as neonatal morbidity, sex or total duration of respiratory support. Head circumference (HC) and cranial volume (CV) were not significantly different between the preterm and term infant group. Digitally measured HC and the CV significantly correlated even in infants with head shape deformities. Our study shows that stereophotogrammetric head assessment is feasible in all preterm and term infants and provides valuable information on volumetry and comprehensive head shape characteristics. In a small sample of preterm infants, body weight at TEA was identified as a specific risk factor for the development of dolichocephaly.

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