scholarly journals Obstetric Outcomes in the Surviving Fetus after Intrauterine Fetal Death in Bichorionic Twin Gestations

Children ◽  
2021 ◽  
Vol 8 (10) ◽  
pp. 927
Author(s):  
María de la Calle ◽  
Jose L. Bartha ◽  
Henar Serrano ◽  
David Ramiro-Cortijo
Keyword(s):  
Fetal Death ◽  
Gestational Hypertension ◽  
Rare Complication ◽  
Intrauterine Fetal Death ◽  
Obstetric Outcomes ◽  
P Value ◽  
La Paz ◽  
Neonatal Complications ◽  
Diabetes Gestational ◽  
Twin Pregnancies

Twin pregnancies are high-risk gestations that increase the odds of obstetrical complications. They can also present specific and rare complications such as single intrauterine fetal death (IUFD). This complication has been extensively studied in monochorionic but not in bichorionic gestations. Today, the repercussions of IUFD may have on the surviving fetus, mother and bichorionic pregnancy are not known. Our objective was to study materno-obstetrical, fetal, and immediate delivery neonatal complications in bichorionic twin gestations with single IUFD compared to those with both fetuses alive. A retrospective and observational case-control study was performed in bichorionic biamniotic twin pregnancies, 22 complicated with single IUFD after 14 weeks (cases; IUFD group) and 51 with both fetuses alive (controls; non-IUFD group, from Obstetrics Service of La Paz Hospital (Madrid; Spain). The data were collected from obstetrical records. No significant differences were found in the rates of gestational diabetes, gestational hypertension, preeclampsia, neonatal complications, and prematurity between IUFD and non-IUFD groups. Statistical differences were found for the incidence of intrauterine growth restriction in the surviving fetus compared to first fetus of pregnancy with both fetuses alive (22.7% versus 2.0%, respectively; p-value = 0.012). There were no differences compared to second fetus (11.8%; p-value = 0.23). There was a high C-section rate in both groups (IUFD = 63.6%, non-IUFD = 64.7%; p-value = 0.19). In conclusion, single IUFD in bichorionic biamniotic twin gestations is a rare complication that should be closely monitored. It is essential that these gestations be attended by a clinical multidisciplinary team.

P10.01: Diffusion MRI findings in monochorionic twin pregnancies after spontaneous intrauterine fetal death

2009 ◽  
Vol 34 (S1) ◽  
pp. 214-214
Author(s):  
S. Lipitz ◽  
B. Weisz ◽  
B. Chayen ◽  
L. Gindes ◽  
R. Achiron ◽  
...  
Keyword(s):  
Diffusion Mri ◽  
Fetal Death ◽  
Intrauterine Fetal Death ◽  
Mri Findings ◽  
Monochorionic Twin ◽  
Twin Pregnancies

scholarly journals Comparison between use of combination of mifepristone and misoprostol versus misoprostol alone in the management of intrauterine fetal death

2018 ◽  
Vol 7 (7) ◽  
pp. 2778
Author(s):  
Sreeveena Talasani ◽  
Pran Hitha Venkamolla ◽  
Kalpana Betha
Keyword(s):  
Side Effects ◽  
Fetal Death ◽  
Intrauterine Fetal Death ◽  
P Value ◽  
Ultrasound Scan ◽  
Efficacy And Safety ◽  
Medical Sciences ◽  
The Mean ◽  
Group 2 ◽  
Group 1

Background: Intrauterine fetal death (IUFD) is estimated to occur in 1% of all pregnancies. The advent of prostaglandins has revolutionized the management of IUFD. There are limited studies using a combined regimen of mifepristone and misoprost for induction of labor in IUFD. Hence this study was undertaken to assess the efficacy and safety of combined regimen with misoprostol alone, in the management of IUFD.Methods: This hospital based prospective study included 60 pregnant women with IUFD admitted at Mediciti Institute of Medical Sciences, during the period January 2015 to July 2016. An ultrasound scan was performed to confirm IUFD and localize the placenta. Women were divided alternatively into 2 groups with 30 in each group (group 1- women received 200 mg mifepristone orally followed by misoprostol after 24 hours & in group 2, 100 µg misoprostol  every 6 hourly for a maximum of 4 doses between gestational age  24-26 weeks, 25-50 µg 4 hourly for a maximum of 6 doses beyond 26 weeks).Results: The mean induction to delivery interval was 10 hours in group 1 and 16.3 hours in group 2 (p value 0.007). Mean dose of misoprostol required in group 1 was 1.87 and 2.67 in group 2 (p value 0.008). With respect to side effects, the two groups did not differ significantly.Conclusions: The combined regimen was more effective than misoprostol for the induction of labour in IUFD, in terms of higher rate of successful delivery and shorter induction to delivery interval. 

A COMPARATIVE STUDY OF MIFEPRISTONE AND MISOPROSTOL VERSUS MISOPROSTOL ALONE IN INDUCTION OF LABOUR IN LATE INTRAUTERINE FETAL DEATH

2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Shivpal Moond ◽  
K.P. Banerjee ◽  
Rakhi Arya
Keyword(s):  
Single Dose ◽  
Comparative Study ◽  
Fetal Death ◽  
Induction Of Labour ◽  
Labour Induction ◽  
Intrauterine Fetal Death ◽  
P Value ◽  
Group A ◽  
The Mean ◽  
Group B

Objective: To compare efficacy, safety and tolerance of combination of Mifepristone and Misoprostol versus Misoprostol alone in induction of labour in late intrauterine fetal death (>24 weeks). Methods: This prospectively study included 160 women with late intrauterine fetal death (IUFD) after 24 weeks of gestation and divided the women randomly into two groups each containing 80 women. In Group-A : Mifepristone 200 mg single dose was given and after 24 hrs Tab Misoprostol (intravaginally) administered and repeated 4 hourly upto a maximum of 5 doses, while in Group-B : Only Tab Misoprostol administered intravaginally 4 hourly upto maximum 5 doses. Induction-delivery interval and number of doses of Misoprostol was calculated.    Results: The mean induction-delivery interval in Group-A was 13.02 ± 3.74 hours and in Group-B was 16.09 ± 2.99 hours (p-value <0.0001). Mean doses of Misoprostol required in Group-A was 3.36 ± 1.08 hours and in Group-B was 4.32 ± 0.65 hours (p-value <0.0001). Conclusion: Combination of Mifepristone and Misoprostol is more effective as comparison to Misoprostol in terms of induction-delivery interval and number of doses of misoprostol required.    Keywords: IUFD, mifepristone, misoprostol, induction of labour, induction-delivery interval.

Effect of Aspirin Dose on Preeclampsia Prevention and Fetal-maternal Complications: A Randomized Clinical Trial

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Maryam Chamani ◽  
Saeid Shahrabi ◽  
Ali Malmir ◽  
Fereshteh Hassanzadeh
Keyword(s):  
Clinical Trial ◽  
Intrauterine Growth Restriction ◽  
Developmental Disorders ◽  
Treatment Process ◽  
Fetal Death ◽  
The Other ◽  
Intrauterine Fetal Death ◽  
P Value ◽  
Maternal Complications ◽  
Intrauterine Growth

Background: Preeclampsia (PE) is a disease characterized by abnormalities in the placenta and endothelial cells. The pathogenesis is not fully understood; however, aspirin prescription can be effective to treat the disease and prevent fetal developmental disorders. Methods: This study was performed as a clinical trial in Shahid Akbrabadi Hospital in Tehran city. Eighty patients participated in two groups (n = 40). The first group of patients received the dose of 80 mg, and the second group received the dose of 160 mg aspirin. Then, the fetal-maternal and treatment process complications were examined in the patients. Results: The results showed that the incidence of fetal-maternal complications, including intrauterine growth restriction (IUGR) and intrauterine fetal death (IUFD) was lower in patients treated with 160 mg aspirin than in the other group, but this difference was not statistically significant (P-value > 0.05). Aspirin complications such as bleeding were more in the second group than in the first one (P-value < 0.05). Conclusions: Although the increasing dose of aspirin reduces fetal-maternal complications in PE patients, the problems such as aspirin-induced bleeding should be considered.

scholarly journals Diffusion MRI Findings in Monochorionic Twin Pregnancies after Intrauterine Fetal Death

2012 ◽  
Vol 34 (1) ◽  
pp. 212-216 ◽  
Author(s):  
C. Hoffmann ◽  
B. Weisz ◽  
Y. Yinon ◽  
L. Hogen ◽  
L. Gindes ◽  
...  
Keyword(s):  
Diffusion Mri ◽  
Fetal Death ◽  
Intrauterine Fetal Death ◽  
Mri Findings ◽  
Monochorionic Twin ◽  
Twin Pregnancies

scholarly journals Prospective Risk of Intrauterine Fetal Death in Monoamniotic Twin Pregnancies

2012 ◽  
Vol 15 (4) ◽  
pp. 522-526 ◽  
Author(s):  
Mamoru Morikawa ◽  
Takashi Yamada ◽  
Takahiro Yamada ◽  
Shoji Sato ◽  
Hisanori Minakami
Keyword(s):  
Fetal Death ◽  
Intrauterine Fetal Death ◽  
Short Term ◽  
Birth Registry ◽  
Term Outcome ◽  
Short Term Outcome ◽  
Registry System ◽  
Gestational Week ◽  
Prospective Risk ◽  
Twin Pregnancies

This study was conducted to review the overall short-term outcome of monoamniotic twins in Japan and to determine the prospective risk of fetal death so as to adequately counsel parents with monoamniotic twins. Study subjects were 101 women with monoamniotic twins who were registered with the Japan Society of Obstetrics and Gynecology Successive Pregnancy Birth Registry System and who had given birth at ≥22 weeks of gestation during 2002–2009. The gestational week at delivery (mean ± SD) was 31.8 ± 3.7. Fourteen women experienced intrauterine fetal death (IUFD). Short-term outcomes of co-twins born to the 14 women included 8 IUFDs, one early neonatal death within 7 days of life (END), and 5 survivors. Four other women experienced 5 ENDs. Thus, 13.9% (28/202) of infants died perinatally (22 IUFDs and 6 ENDs), 13.9% (14/101) of women experienced IUFD, and 82.2% (83/101) of women experienced neither IUFD nor END. Structural anomalies and twin-to-twin transfusion syndrome explained 17.9% (five infants) and 10.7% (three infants) of the 28 perinatal deaths, respectively. The prospective risk of IUFD was 13.9% (14/101) for women who reached gestational week 22−0/7, gradually decreasing thereafter but remaining at between 4.5% and 8.0% between gestational week 30−0/7 and 36−0/7.

scholarly journals Women Aged over 40 with Twin Pregnancies Have a Higher Risk of Adverse Obstetrical Outcomes

2021 ◽  
Vol 18 (24) ◽  
pp. 13117
Author(s):  
María De la Calle ◽  
Jose L. Bartha ◽  
Laura García ◽  
Marcos J. Cuerva ◽  
David Ramiro-Cortijo
Keyword(s):  
Risk Factor ◽  
Retrospective Cohort ◽  
Maternal Age ◽  
Independent Risk Factor ◽  
Adverse Outcomes ◽  
Obstetric Outcomes ◽  
P Value ◽  
Labor Complications ◽  
Twin Pregnancies ◽  
Over 40 Years

Maternal age is related to a higher risk of adverse maternal, fetal, and neonatal outcomes in twin pregnancies. However, whether this increase in adverse outcomes is due solely to age or due to risk factors that are more common in women over 40 remains unknown. The aim of this study is to assess if maternal age over 40 years old is an independent risk factor for obstetric adverse outcomes in dichorionic diamniotic twin gestations. In this single-center retrospective cohort study, we compared the obstetric outcomes of women with dichorionic diamniotic twin pregnancies below and over 40 years of age. A twin pregnancy cohort enrolled between 2013 and 2019 was included in the study. Maternal, fetal, and labor complications were recorded. A total of 510 women were analyzed in two groups: 266 women below 40 years old and 244 women over 40 years old. Maternal age over 40 increased the odds of maternal (aOR = 1.9 (1.3; 2.9); p-value = 0.002), fetal (aOR = 1.8 (1.0; 3.0); p-value = 0.037), and labor complications (aOR = 2.5 (1.3; 4.6); p-value = 0.004). Maternal age over 40 years was the most important factor increasing the odds of having a caesarean section (C-section). Over 40 years old was an independent risk factor for complications in dichorionic diamniotic twin pregnancies.

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