scholarly journals Characterization and Pathogenic Speculation of Xerostomia Associated with COVID-19: A Narrative Review

2021 ◽  
Vol 9 (11) ◽  
pp. 130
Author(s):  
Hironori Tsuchiya
Keyword(s):  
Close Association ◽  
Renin Angiotensin System ◽  
Cranial Neuropathy ◽  
Mouth Dryness ◽  
Related Quality ◽  
Health Related ◽  
Narrative Literature ◽  
Oral Symptoms ◽  
Narrative Literature Review ◽  
Taste Dysfunction

Patients with coronavirus disease 2019 (COVID-19) have become known to present with different oral symptoms. However, xerostomia remains poorly recognized compared with taste dysfunction. For better understanding of COVID-19 symptomatology, xerostomia associated withCOVID-19 was characterized and its possible pathogenesis was speculated by a narrative literature review. Scientific articles were retrieved by searching PubMed, LitCovid, ProQuest, Google Scholar, medRxiv and bioRxiv from 1 April 2020 with a cutoff date of 30 September 2021. Results of the literature search indicated that xerostomia is one of prevalent and persistent oral symptoms associated with COVID-19. In contrast to taste dysfunction, the prevalence and persistence of xerostomia do not necessarily depend on ethnicity, age, gender and disease severity of patients. COVID-19 xerostomia is pathogenically related to viral cellular entry-relevant protein expression, renin-angiotensin system disturbance, salivary gland inflammation, zinc deficiency, cranial neuropathy, intercurrent taste dysfunction, comorbidities and medications. Despite a close association with COVID-19, xerostomia, dry mouth and hyposalivation tend to be overlooked unlike ageusia, dysgeusia and hypogeusia. Although mouth dryness per se is not life-threating, it has an impact on the oral health-related quality of life. More attention should be paid to xerostomia in COVID-19 patients and survivors.

scholarly journals The consequences of living with a severe malocclusion: A review of the literature

2021 ◽  
pp. 146531252110428
Author(s):  
Richard Leck ◽  
Ninu Paul ◽  
Sarah Rolland ◽  
David Birnie
Keyword(s):  
Literature Review ◽  
Research Evidence ◽  
Decision Making Process ◽  
Shared Decision ◽  
Dental Injury ◽  
Related Quality ◽  
Health Related ◽  
Narrative Literature ◽  
Narrative Literature Review

Aim: To facilitate the orthognathic shared decision-making process by identifying and applying existing research evidence to establish the potential consequences of living with a severe malocclusion. Methods: A comprehensive narrative literature review was conducted to explore the potential complications of severe malocclusion. A systematic electronic literature search of four databases combined with supplementary hand searching identified 1024 articles of interest. A total of 799 articles were included in the narrative literature review, which was divided into 10 themes: Oral Health Related Quality Of Life; Temporomandibular Joint Dysfunction; Masticatory Limitation; Sleep Apnoea; Traumatic Dental Injury; Tooth Surface Loss; Change Over Time; Periodontal Injury; Restorative Difficulty; and Functional Shift and Dual Bite. A deductive approach was used to draw conclusions from the evidence available within each theme. Results: The narrative literature review established 27 conclusions, indicating that those living with a severe malocclusion may be predisposed to a range of potential consequences. With the exception of Oral Health Related Quality Of Life, which is poorer in adults with severe malocclusion than those with normal occlusions, and the risk of Traumatic Dental Injury, which increases when the overjet is >5 mm in the permanent and 3 mm in the primary dentition, the evidence supporting the remaining conclusions was found to be of low to moderate quality and at high risk of bias. Conclusion: This article summarises the findings of a comprehensive narrative literature review in which all of the relevant research evidence within a substantive investigative area is established and evaluated. Notwithstanding limitations regarding the quality of the available evidence; when combined with clinical expertise and an awareness of individual patient preferences, the conclusions presented may facilitate the orthognathic shared decision-making process and furthermore, may guide the development of the high-quality longitudinal research required to validate them.

scholarly journals Burden of Oral Symptoms and Health-Related Quality of Life in Long-Term Care Settings in Helsinki, Finland

2019 ◽  
Vol 23 (10) ◽  
pp. 1021-1025 ◽  
Author(s):  
Riitta K. T. Saarela ◽  
N. M. Savikko ◽  
H. Soini ◽  
S. Muurinen ◽  
M. H. Suominen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Long Term Care ◽  
Health Related Quality ◽  
Term Care ◽  
Related Quality ◽  
Health Related ◽  
Oral Symptoms

scholarly journals Oral symptoms and oral health-related quality of life of individuals with x-linked hypophosphatemia

2019 ◽  
Vol 15 (1) ◽  
Author(s):  
Marcel Hanisch ◽  
Lauren Bohner ◽  
Martin M. I. Sabandal ◽  
Johannes Kleinheinz ◽  
Susanne Jung
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Oral Symptoms

4 A Cross-Sectional Study of the Oral Health and Oral-Health-Related Quality of Life of Older Adults Admitted to An Acute Hospital in the North East of England

2021 ◽  
Vol 50 (Supplement_1) ◽  
pp. i1-i6
Author(s):  
B J Steel
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Cross Sectional Study ◽  
Health Related Quality ◽  
Sectional Study ◽  
Cross Sectional ◽  
Related Quality ◽  
Health Related ◽  
Oral Symptoms

Abstract Introduction Oral health has a strong relationship with general health, wellbeing and quality of life. The importance of establishing and protecting oral health in older adults is increasingly recognised. Admission to an acute hospital can be a good opportunity to assess and intervene with oral health, however data on the oral health of this population are very sparse. Methods A cross-sectional study of adults aged over 65 admitted to the acute medical ward within the Northumbria Specialist Emergency Care Hospital, Northumberland. Ethical approval was granted and all participants gave written consent. Data were obtained via verbal questions and a bedside visual examination by a dentist. Recorded were—gender, age, time since last dental visit, current oral symptoms, number of teeth present, number of decayed teeth, requirement for dental treatment, global oral health including health of hard and soft tissues and oral hygiene using the Oral Health Assessment Tool (OHAT) and oral-health-related quality of life using the Gohai scale. Results 32 participants took part, 16 male and 16 female, of average age 81.9 (range 69–94). Time since last dental visit ranged from a few months to 30+ years. 14 complained of oral dryness and 7 of loose dentures. 15 had no current oral symptoms. 18 participants had no teeth. The remainder had an average of 13.3 teeth of which 5.8 were restored. 22 had dentures. 9 had active dental disease requiring treatment. OHAT score (with 0 indicating perfect health and 14 the worst score) mean 3.6. Gohai score (scored from 12 indicating best to 60 indicating worst quality of life) mean 19.4 and range 14–33. Conclusions The dental status of this group is variable but this study indicates the presence of troublesome oral symptoms and active dental disease requiring treatment, with a significant number not having seen a dentist for some time.

scholarly journals Oral symptoms and oral health-related quality of life in patients with chronic kidney disease from predialysis to posttransplantation

2018 ◽  
Vol 23 (5) ◽  
pp. 2207-2213 ◽  
Author(s):  
Hellevi Ruokonen ◽  
Karita Nylund ◽  
Jukka H. Meurman ◽  
Anna M. Heikkinen ◽  
Jussi Furuholm ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Oral Health ◽  
Kidney Disease ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Oral Symptoms

scholarly journals Oral Symptoms and Oral Health-Related Quality of Life in People with Rare Diseases in Germany: A Cross-Sectional Study

2018 ◽  
Vol 15 (7) ◽  
pp. 1493 ◽  
Author(s):  
Sabrina Wiemann ◽  
Nicolas Frenzel Baudisch ◽  
Rainer Jordan ◽  
Johannes Kleinheinz ◽  
Marcel Hanisch
Keyword(s):  
Quality Of Life ◽  
Cluster Analysis ◽  
Oral Health ◽  
Rare Diseases ◽  
Health Related Quality ◽  
Mean Values ◽  
Related Quality ◽  
Health Related ◽  
Oral Symptoms

Background: The aim of this study was to collect information on oral health-related quality of life (OHRQoL) in people with rare diseases. Methods: A questionnaire comprising free text questions and the German version of the standardized Oral Health Impact Profile-14 (OHIP-14) questionnaire on OHRQoL was developed. All participants who indicated oral symptoms in the questionnaire were included in a cluster analysis. Different cluster analyses were performed (Ward’s, k-Means) to find symptom profile groups in the data. Results: A total of 484 questionnaires with 96 rare diseases were included in the study. The most reported symptoms were anomalies of the tooth formation, dysgnathia, changes in number of the teeth, and malocclusions. The OHIP mean values of the five resulting symptom clusters ranged from 15.1 to 19.9, which is very high compared to the general population in Germany, which has a mean value of 4.09. Discussion: All investigated symptoms show a negative association with OHRQoL, but the strongest were for symptoms of the oral mucosa and periodontal diseases. All the symptoms described in this cluster analysis can lead to considerably higher mean values of the OHIP total score among people with rare disease and thus to worse OHRQoL than reported in the general population.

scholarly journals Impact of anterior occlusal conditions in the mixed dentition on oral health–related quality-of-life item levels:

2020 ◽  
Vol 90 (4) ◽  
pp. 564-570
Author(s):  
Silvia A.S. Vedovello ◽  
Ana Letícia Mello de Carvalho ◽  
Larissa C. de Azevedo ◽  
Patrícia R. dos Santos ◽  
Mario Vedovello-Filho ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Well Being ◽  
Mixed Dentition ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Oral Symptoms ◽  
The Impact

ABSTRACT Objectives To evaluate the impact of anterior occlusal conditions in the mixed dentition on item-level analysis of oral health–related quality of life (OHRQoL). Materials and Methods A population-based cross-sectional study of 787 children aged 8 to 10 years was conducted. The Child Perceptions Questionnaire (CPQ8-10) was used to evaluate OHRQoL, and the analysis of item levels was performed on CPQ8-10 domains. Anterior occlusal characteristics were diagnosed according to the Dental Aesthetic Index criteria. Individual analyses were performed relating the outcome as independent variables. The variables with P < .20 in the individual analyses were tested in multiple logistic regression models, and those with P < .10 remained in the model. The adjusted odds ratio (OR) was estimated with a 95% confidence interval (CI). Results No associations were found with regard to anterior occlusal characteristics (P < .001) after the variables of the previous determinants were adjusted for multivariate analysis. However, the following variables were significantly associated with negative impact on OHRQoL item levels: sex, in oral symptoms (OR = 1.42; CI, 1.07–1.89) and emotional well-being (OR = 1.34; CI, 1.00–1.79); race, in oral symptoms (OR = 1.48; CI, 1.10–1.98), emotional well-being (OR = 1.54; CI, 1.14–2.06), and social well-being (OR = 1.34; CI, 1.00–1.80); and family income in functional limitation (OR = 1.46; CI, 1.06–2.02), emotional well-being (OR = 1.71; CI, 1.21–2.42), and social well-being (OR = 1.59; CI, 1.14–2.21). Conclusions Anterior occlusal conditions did not affect the levels of OHRQoL items.

scholarly journals Oral Health-Related Quality of Life in People with Achalasia

Medicina ◽  
2020 ◽  
Vol 56 (6) ◽  
pp. 286
Author(s):  
Marcel Hanisch ◽  
Sabrina Wiemann ◽  
Lauren Bohner ◽  
Susanne Jung ◽  
Johannes Kleinheinz ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Survey Study ◽  
Free Text ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Oral Symptoms ◽  
The Mean

Background and Objective: The oral health-related quality of life (OHRQoL) of patients with achalasia has not been evaluated to date. Therefore, the aim of this study was to assess the OHRQoL of patients with achalasia and to get information about the time taken for diagnosis and oral symptoms. Materials and Methods: The study was conceived of as an anonymous epidemiological survey study in people with achalasia in order to assess their OHRQoL in each case. For this, a questionnaire was developed consisting of free-text questions and of the standardized German version of the OHIP-14 questionnaire. Results: In total, forty-four questionnaires were analyzed including 31 female and 13 male participants. Regardless of gender, the mean age was 50.57 years (range: 17–78). Of the surveyed individuals, seventy-nine-point-five-five percent had been diagnosed between 25 and 60 years of age. The period from the first signs of the disease to diagnosis was 6.15 years, irrespective of gender. The overall OHIP-14 score without gender differentiation was 8.72 points (range 0–48); the mean score of female participants was 11.13 (range: 0–48), and the OHIP score of male participants was 3.15 on average. Two participants reported oral symptoms. Conclusions: The already known problem of the delayed diagnosis of rare diseases was also confirmed in the case of achalasia. Females with achalasia seemed to be significantly affected by lower OHRQoL than males with achalasia and women of the general population. Demineralization of the tooth structure was described in two participants.

scholarly journals Oral Health-Related Quality of Life in People with Rare Hereditary Connective Tissue Disorders: Marfan Syndrome

2018 ◽  
Vol 15 (11) ◽  
pp. 2382 ◽  
Author(s):  
Marcel Hanisch ◽  
Sabrina Wiemann ◽  
Susanne Jung ◽  
Johannes Kleinheinz ◽  
Lauren Bohner
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Marfan Syndrome ◽  
Correct Diagnosis ◽  
Health Related Quality ◽  
Significance Level ◽  
Related Quality ◽  
Health Related ◽  
Oral Symptoms

Background: The aim of this study was to analyze data on oral health-related quality of life (OHRQoL) in people with Marfan syndrome and to obtain information on the diagnosis period, orthodontic treatment, and oral symptoms. Methods: A questionnaire was developed consisting of open questions and the standardized German version of the OHIP-14 (Oral Health Impact Profile) questionnaire for the evaluation of OHRQoL. The age of diagnosis, time period from the first signs of the disease to diagnosis, and OHIP-values were compared between male and female participants. Additionally, the OHIP-values between participants who were orthodontically treated and those who were not treated were assessed. The statistical analysis was performed using the Mann–Whitney test with a significance level at p = 0.05. Results: A total of 51 questionnaires were evaluated, which included 34 female and 17 male participants. Overall, 84% of respondents reported oral symptoms. Male respondents tended to diagnose the disease earlier (p = 0.00), with a smaller period between the first symptom and the diagnosis (p = 0.04). The OHIP-14 score was gender-neutral at 13.65 ± 13.53 points. Conclusion: In Marfan syndrome, many years (12.01 ± 11.61) elapse between the onset of first symptoms and correct diagnosis of the disease. People with Marfan syndrome have a worse OHRQoL than do the general population.

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