scholarly journals Resistant Starch Combined with Whey Protein Increases Postprandial Metabolism and Lowers Glucose and Insulin Responses in Healthy Adult Men

Foods ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 537
Author(s):  
Alex E. Mohr ◽  
Olivia Minicucci ◽  
Dale Long ◽  
Vincent J. Miller ◽  
Allison Keller ◽  
...  

Resistant starch (RS) and/or protein consumption favorably influence energy metabolism, substrate utilization, and weight management. The current study administered four different versions of a pancake breakfast containing waxy maize or RS with and without whey protein (WP) and measured postprandial thermogenesis (TEM), fuel utilization, and circulating satiation and appetite factors for 180 min in a group of healthy, adult men. On four separate visits to the laboratory, eight participants were administered four different pancake breakfast meal challenges using a single-blind, randomized crossover design: (1) waxy maize starch (WMS) control; (2) WMS and WP (WMS + WP); (3) RS; or (4) RS and WP (RS + WP). TEM (kcals/180 min) was significantly greater (p < 0.05) in RS + WP (45.11; confidence interval (CI), 33.81–56.41) compared to WMS (25.61; CI, 14.31–36.91), RS (29.44; CI, 18.14–40.74), and WMS + WP (24.64; CI, 13.34–35.94), respectively. Fat oxidation was enhanced (p < 0.05) after RS + WP compared to RS at 60 min (+23.10%), WMS at 120 min (+27.49%), and WMS and WMS + WP at 180 min (+35.76%; +17.31%, respectively), and RER was decreased with RS + WP versus the other three meals (mean differences: ≥−0.021). Insulin concentrations were decreased (p < 0.05) following RS + WP compared to WMS, whereas both RS (−46.19%) and RS + WP (−53.05%) insulin area under the curve (AUC) were greatly reduced (p < 0.01) compared to WMS. While limited by sample size, meals containing both RS and WP increased postprandial thermogenesis and fat oxidation, and lowered insulin response compared to isocaloric meals without this combination. Therefore, RS + WP may favorably impact energy metabolism and thus weight control and body composition under chronic feeding conditions.

2016 ◽  
Vol 104 (4) ◽  
pp. 995-1003 ◽  
Author(s):  
Thomas MS Wolever ◽  
B Jan-Willem van Klinken ◽  
Nicolas Bordenave ◽  
Melissa Kaczmarczyk ◽  
Alexandra L Jenkins ◽  
...  

Author(s):  
Shogo Sakai ◽  
Noriaki Maeda ◽  
Junpei Sasadai ◽  
Somu Kotoshiba ◽  
Keitaro Anami ◽  
...  

Author(s):  
Alison N Beloshapka ◽  
Tzu-Wen L Cross ◽  
Kelly S Swanson

Abstract Resistant starch (RS) is fermentable by gut microbiota and effectively modulates fecal short-chain fatty acid concentrations in pigs, mice, and humans. RS may have similar beneficial effects on the canine gut, but has not been well studied. The objective of this study was to evaluate the effects of 0, 1, 2, 3, and 4% dietary RS (Hi-maize 260) on apparent total tract macronutrient digestibility, and fecal characteristics, fermentative end-product concentrations, and microbiota of healthy adult dogs. An incomplete 5 x 5 Latin square design with 7 dogs and 5 experimental periods was used, with each treatment period lasting 21 d (d 0-17 adaptation; d 18-21 fresh and total fecal collection) and each dog serving as its own control. Seven dogs (mean age = 5.3 yr; mean BW = 20 kg) were randomly allotted to one of five treatments formulated to be iso-energetic and consisting of graded amounts of 100% amylopectin cornstarch, RS, and cellulose, and fed as a top dressing on the food each day. All dogs were fed the same amount of a basal diet throughout the study and fresh water was offered ad libitum. The basal diet contained 6.25% RS (DM basis), contributing approximately 18.3 g of RS/d based on their daily food intake (292.5 g DM/d). Data were evaluated for linear and quadratic effects using SAS. The treatments included 0%, 1%, 2%, 3%, and 4% of an additional RS source. Because Hi-maize 260 is approximately 40% digestible and 60% indigestible starch, the dogs received the following amounts of RS daily: 0% = 18.3 g (18.3 g + 0 g); 1% = 20.1 g (18.3 g + 1.8 g); 2% = 21.9 g (18.3 g + 3.6 g); 3% = 23.7 g (18.3 g + 5.4 g); and 4% = 25.5 g (18.3 g + 7.2 g). Apparent total tract dry matter, organic matter, crude protein, fat, and gross energy digestibilities and fecal pH were linearly decreased (P &lt; 0.05) with increased RS consumption. Fecal output was linearly increased (P &lt; 0.05) with increased RS consumption. Fecal scores and fecal fermentative end-product concentrations were not affected by RS consumption. Although most fecal microbial taxa were not altered, Faecalibacterium were increased (P &lt; 0.05) with increased RS consumption. The decrease in fecal pH and increase in fecal Faecalibacterium would be viewed as being beneficial to gastrointestinal health. Although our results seem to indicate that RS is poorly and/or slowly fermentable in dogs, the lack of observed change may have been due to the rather high level of RS contained in the basal diet.


1999 ◽  
Vol 46 (4) ◽  
pp. 605-612 ◽  
Author(s):  
TOSHIAKI TANAKA ◽  
YOSHIKI SEINO ◽  
KENJI FUJIEDA ◽  
YUTAKA IGARASHI ◽  
SUSUMU YOKOYA ◽  
...  

Author(s):  
Hilkka Kontro ◽  
Marta Kozior ◽  
Gráinne Whelehan ◽  
Miryam Amigo-Benavent ◽  
Catherine Norton ◽  
...  

Supplementing postexercise carbohydrate (CHO) intake with protein has been suggested to enhance recovery from endurance exercise. The aim of this study was to investigate whether adding protein to the recovery drink can improve 24-hr recovery when CHO intake is suboptimal. In a double-blind crossover design, 12 trained men performed three 2-day trials consisting of constant-load exercise to reduce glycogen on Day 1, followed by ingestion of a CHO drink (1.2 g·kg−1·2 hr−1) either without or with added whey protein concentrate (CHO + PRO) or whey protein hydrolysate (CHO + PROH) (0.3 g·kg−1·2 hr−1). Arterialized blood glucose and insulin responses were analyzed for 2 hr postingestion. Time-trial performance was measured the next day after another bout of glycogen-reducing exercise. The 30-min time-trial performance did not differ between the three trials (M ± SD, 401 ± 75, 411 ± 80, 404 ± 58 kJ in CHO, CHO + PRO, and CHO + PROH, respectively, p = .83). No significant differences were found in glucose disposal (area under the curve [AUC]) between the postexercise conditions (364 ± 107, 341 ± 76, and 330 ± 147, mmol·L−1·2 hr−1, respectively). Insulin AUC was lower in CHO (18.1 ± 7.7 nmol·L−1·2 hr−1) compared with CHO + PRO and CHO + PROH (24.6 ± 12.4 vs. 24.5 ± 10.6, p = .036 and .015). No difference in insulin AUC was found between CHO + PRO and CHO + PROH. Despite a higher acute insulin response, adding protein to a CHO-based recovery drink after a prolonged, high-intensity exercise bout did not change next-day exercise capacity when overall 24-hr macronutrient and caloric intake was controlled.


2001 ◽  
Vol 65 (6) ◽  
pp. 1353-1357 ◽  
Author(s):  
Yasuhiro TOBA ◽  
Yukihiro TAKADA ◽  
Yasuhiro MATSUOKA ◽  
Yoshikazu MORITA ◽  
Mutsumi MOTOURI ◽  
...  

1999 ◽  
Vol 276 (5) ◽  
pp. E964-E976 ◽  
Author(s):  
Anders H. Forslund ◽  
Antoine E. El-Khoury ◽  
Roger M. Olsson ◽  
Anders M. Sjödin ◽  
Leif Hambraeus ◽  
...  

Effects of moderate physical activity (90 min at 45–50% of maximal O2 uptake 2 times daily) and “high” (2.5 g protein ⋅ kg−1 ⋅ day−1, n = 6) or “normal” protein intake (1.0 g protein ⋅ kg−1 ⋅ day−1, n = 8) on the pattern and rate of 24-h macronutrient utilization in healthy adult men were compared after a diet-exercise-adjustment period of 6 days. Energy turnover (ET) was determined by indirect and direct (suit) calorimetry, and “protein oxidation” was determined by a 24-h continuous intravenous infusion of [1-13C]leucine. Subjects were in slight positive energy balance during both studies. Protein contributed to a higher (22 vs. 10%) and carbohydrate (CHO) a lower (33 vs. 58%) proportion of total 24-h ET on the high- vs. normal-protein intake. The highest contribution of fat to ET was seen postexercise during fasting (73 and 61% of ET for high and normal, respectively). With the high-protein diet the subjects were in a positive protein ( P < 0.001) and CHO balance ( P < 0.05) and a negative fat balance ( P < 0.05). The increased ET postexercise was not explained by increased rates of urea production and/or protein synthesis.


2010 ◽  
Vol 24 (S1) ◽  
Author(s):  
Christopher Tomlinson ◽  
Mahroukh Rafii ◽  
Ronald O. Ball ◽  
Paul Pencharz

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