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2475-5494

2021 ◽  
Vol 10 (4) ◽  
pp. 107-109
Author(s):  
Sally Damra Elnour Mohammed ◽  
Rami Salaheldien ◽  
Badreldeen Ahmed

Congenital cervical teratomas are rare tumours of germ cells that should be diagnosed antenatally by ultrasound during anomaly scan or even earlier. The incidence of teratomas of the head and neck is 3-5%. We are presenting a case of rare cervical teratoma.1 Congenital cervical tumours are often clinically dramatic, though basically benign. Prognosis is favourable only if the airway is quickly stabilized and necessarily surgical procedure is planned and executed effectively.2 Case presentation: A 34-year-old female presented at 32 weeks of gestation, at Al Amal National Hospital where an ultrasound examination revealed a single viable cephalic fetus with a huge irregular heterogeneous anterior neck mass suspected as congenital cervical neck teratoma. The delivery was planned at 37 weeks gestation. The team was assembled for EXIT procedure which includes the obstetricians, neonatologist, anthologist, ENT surgeons. At 37 weeks of gestation, the child was maintained on maternal circulation after caesarean section until successfully intubated (Extra Uterine Intrapartum Treatment (EXIT) was performed at Al Amal National Hospital after liaison with the anesthetist, neonatologist and the pediatric surgeon. A female fetus weighing 3.8 kg was delivered and intubated immediately. Unfortunately, the newborn died at 48hours of age. Conclusion: Prenatally diagnosed head and neck teratomas can result in early neonatal death if the delivery was not planned correctly with right multidisciplinary team. In this case EXIT is the procedure of choice.


2021 ◽  
Vol 10 (4) ◽  
pp. 102-105
Author(s):  
Rupakala BM ◽  
K Anbazhaganb ◽  
S Prabhakarac ◽  
MPA Sailakshmia

Background: Osteoporosis in post-menopausal women is known to progress periodically and is highly associated with inflammation. MicroRNAs regulate inflammatory process, which may therefore control bone metabolism. Deregulation of miRNAs associated with inflammation may lead to development and progression of osteoporosis. We selected four miRNAs known to be involved in inflammation to test their association with post-menopausal osteoporosis. Methods: We quantified four circulating miRNAs, hsa-miR-139-5p, hsa-miR-342-3p, hsa-miR-146a and hsa-miR-24-3p in plasma samples of 25 post-menopausal osteoporosis and 25 post-menopausal healthy subjects. Related biochemical tests were done using Cobas e411 and ELISA. Results: Upon quantification of circulating miRNAs, we observed that hsa-miR-139-5p was expressed higher in post-menopausal osteoporotic samples (p=0.01). The expression of hsa-miR-24-3p was seen lower in osteoporotic samples though not highly significant (p=0.2). Conclusion: Differential expression of hsa-miR-139-5p and hsa-miR-24-3p was seen in osteoporosis subjects. These miRNA could be significantly involved in development and progression of osteoporosis. Further studies are required to highlight miRNAs’ involvement in regulating bone metabolism, which could be manipulated to use them as marker or therapeutic strategies to alleviate osteoporosis.


2021 ◽  
Vol 10 (4) ◽  
pp. 97-100
Author(s):  
Makhlie Zh Aslonova ◽  
Ikhtiyarova GA ◽  
Mavlyanova NN

The article presents a molecular genetic study of the ITGB3 gene polymorphism in pregnant women with fetal growth restriction syndrome. Purpose: Assessment of the detectability of the association of the ITGB3 gene polymorphism in women with physiological pregnancy and fetal growth restriction syndrome in the uzbek population of the Bukhara region. Materials and methods: 80 pregnant women were examined during gestation from 8-36 weeks: 40 pregnant women with fetal growth restriction syndrome and 40 women with physiological pregnancy, hospitalized in the department of pathology of pregnant women in the Bukhara city maternity hospital in the city of Bukhara. Conclusion: The study showed that the functionally unfavorable allele C and the association of the T / C genotype polymorphism of the ITGB3 gene polymorphism can be a determinant of an increased risk of developing FGRS in Uzbekistan (χ2 <0.47; P> 0.05).


2021 ◽  
Vol 10 (4) ◽  
pp. 85-89
Author(s):  
Panayiotis Michael Zavos

Male infertility is linked to some viral infections including human papillomavirus (HPV), herpes simplex viruses (HSV) and human immunodeficiency viruses (HIVs). As for acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), its effects on worldwide declines in sperm count and fertility have not been researched thoroughly. With the recent increase of viral infections due to the pandemic, the potential negative impacts that SARS-CoV-2 will have on male reproductive organs and male fertility have raised countless concerns. This review article aims to discuss the possible effects that the SARS-CoV-2 pandemic will have on an already declining male reproductive success while integrating the results of recent studies focusing on similar topics. Furthermore, this article will also mention the future implications that come with a more infertile population. Within the articles studied, it has become apparent that the SARS-CoV-2 pandemic has and will only decrease men’s sperm quality further. These findings became apparent through the study of oxidative stress established through the sperm’s production of reactive oxygen species1 and the COVID-19 virus’ ability to attack human spermatozoa produced in the testes due the expression of the ACE2 gene.2 As for the decline in male fertility prior to the SARS-CoV-2 pandemic, there are many factors to be discussed, some of which include: tobacco consumption, alcoholism, diet, electronics, and higher rates of testicular cancer.3


2021 ◽  
Vol 10 (3) ◽  
pp. 63-64
Author(s):  
Sanjay Jayawant Rode

Corona virus emerged from Sea food market, China but it affected on all countries including women, men and children. Women are most affected economically, emotionally and work by Corona virus. Immediately after the outbreak of corona virus, Central and State governments introduced lockdown of economy. All women working in an informal sector lost their job and income. Those women working in formal sector had more online workload without time constraints. Household chores, child care, family members care, carry vegetables and grocery was routine activities for women. Such activities increased more work burden on women. Other member were expected to cooperate to women in work but they never cooperated to women. Over work and family related violence made women more worse in this pandemic.


2021 ◽  
Vol 10 (1) ◽  
pp. 5-6
Author(s):  
Nourah Al Kindi ◽  
Fatima Al Shalabi ◽  
Shabana Kapadia ◽  
Asma Jan

2021 ◽  
Vol 10 (3) ◽  
pp. 51-61
Author(s):  
Yohannes Mekonen ◽  
Hermon Berhe ◽  
Luam Ghebreab ◽  
Elias Teages

Background: Cervical cancer is one of the leading causes of cancer-related deaths worldwide that affects developing countries and young women in particular. Out of many types of female cancers, cancer of the cervix could be prevented if appropriate medical interventions are taken on time. Pap smear is a means for early detection of premalignant stages and treatment before the disease advances to a late stage. However, its practice remains unsatisfactory in many countries including Eritrea. Objective: The aim of the study was to illustrate knowledge, attitude and level of cervical cancer and Pap smear practice and associated factors among female students of Orotta College of Medicine and Health sciences (OCMHS). Methods: A cross-sectional study was conducted among female undergraduate students in OCMHS enrolled during the academic year 2018-2019. A total of 252 students participated in the study. Piloted, structured questionnaire was used to collect data. Descriptive and inferential statistics were used to assess the distribution and to identify associations between independent and outcome variables respectively. Results: Majority of the students, 171 (68.4%), were 18-21 years old and 159 (63.6%) were second and third year students. One hundred thirty six (54.4%) students had inadequate knowledge and one hundred twenty three (49.2%) had negative attitude towards cervical cancer screening. Only two (0.8%) participants had ever been screened with Pap smear test. Logistic regression analysis showed that age, level of education and year of study were significantly associated with knowledge of cervical cancer and its screening methods. Year of study and knowledge levels were significantly associated with attitude towards cervical cancer screening (Pap smear). Conclusions: The study showed that there is a lack of knowledge of cervical cancer, unfavorable attitude towards screening methods and poor utilization of Pap smear. The study emphasized the importance of creating awareness and increasing knowledge of cervical cancer and Pap smear through numerous health education campaigns and mass media. Hence, it will be vital to integrate cervical cancer preventive measures with other reproductive health care services at all, if not at the highest, levels of health care delivery system.


2021 ◽  
Vol 10 (2) ◽  
pp. 29-34
Author(s):  
Sintayehu Abebe ◽  
Abayneh Tunja ◽  
Woiynshet Gebretsadik

Introduction: Unintended pregnancies and unplanned births can have serious health, economic, and social consequences for women and their families. The immediate outcome of some unintended pregnancies is induced abortion which is unsafe in many countries that have highly restrictive abortion laws. In these countries, abortion often damages women’s health and sometimes results in their death. Method: A community based cross-sectional study was conducted. A total of 420 study participants were recruited. Simple random sampling was used to draw participants; the collected data were entered into EPI- Data version (7.9.0.) and then exported to SPSS Version 20.0 for analysis. Descriptive statistics, binary and multiple logistic regression analysis were carried out, Odds ratio with 95% CI were calculated. Result: the prevalence of unintended pregnancy was found to be 30.2%. Multiple logistic regression results showed that the previous history of abortion (AOR=8.262; 95%CI=3.692, 18.489), not discussing the sexual reproductive health (SRH) issues with their husband (AOR=3.086; 95%CI=1.830, 5.205) age of the last child less than three years (AOR=1.870; 95%CI=1.100, 3.179) were significantly associated with unintended pregnancy. Conclusion: This study shown that the prevalence of unintended pregnancy is high in the study area, hence, strengthening the provision of post abortion services, counseling on long term family planning services and male involvement in all reproductive health services are highly recommended.


2021 ◽  
Vol 10 (1) ◽  
pp. 18-20
Author(s):  
Mohammed Ahmed Ibrahim Ahmed ◽  
Hanaa Elzain Musaad ◽  
Nahla Ahmed Mohammed Abdurrahman ◽  
Wadei Mohammed Yasin ◽  
Mosab Nouraldein Mohammed Hamad ◽  
...  

Objective: The aim of this study was to find the seroprevalence of TORCH infection among volunteered pregnant women and to find out the correlation between TORCH infection and age, complicated pregnancies and education level. Methods: A descriptive cross-sectional laboratory-based study carried out between March to June 2012 at Atbara River Nile State northern Sudan. The statistical descriptive determined in means of percentages. Chi-square used for trend analysis and calculates p-values. Results: A total of (75) voluntary pregnant women, Age between 15-55 years. The most common age group was 26-35 years (37/75) 49%.Serological evidence of Toxoplasmosis were positive for (22/75) 29 %. All volunteered pregnant women were negative for other components of TORCH complex. Study showed non-significant correlation between age, education level and complicated pregnancies, P-value 0.13, 0.43 and 0.51 respectively. Conclusion: Low prevalence of Toxoplasmosis and absent of serological evidence of other TORCH complex among volunteered pregnant women in Atbara has been documented. Insignificant correlation between toxoplasmosis and age, education level as well as number of complicated pregnancies reported. This attributed, in part, to the small sample size and using screening tool as diagnostic modalities.


2021 ◽  
Vol 10 (2) ◽  
pp. 41-44
Author(s):  
Aisha Ansari ◽  
Mohammad Shahid Ali

Background: Some studies have demonstrated that physiotherapists have a high prevalence of low back pain (LBP). The relationship between physiotherapy students, who are possibly open to the same LBP professional risks as graduates, and LBP has never been established. Objective: The objective of the study is to evaluate the association between undergraduate physiotherapy study and LBP. Settings: University of Hail, female Campus. Methodology: This cross-sectional study was carried out at University of Hail, K.S.A. A survey-based learning was carried out with physiotherapy and medical students. The target population of this study consists of 120 medical and physiotherapy students, where 60 were Medical and 60 were physiotherapy students. The sample was randomly selected from the University of Hail (female campus). The Social Package for Social Sciences (SPSS) version 18.0 (SPSS Inc, Chicago, IL, USA) will be used to analyze the entered data. Descriptive statistics such as Chi square test, U test, correlation, graphs as well as percentages will be used to describe the participants. Result: Physiotherapy students reported a higher prevalence of LBP when compared with the medical students in all measures. There were no changes between the courses regarding pain intensity and disability.


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