scholarly journals House Dust Avoidance during Pregnancy and Subsequent Infant Development: The Japan Environment and Children’s Study

2021 ◽  
Vol 18 (8) ◽  
pp. 4277
Author(s):  
Kenta Matsumura ◽  
Kei Hamazaki ◽  
Akiko Tsuchida ◽  
Hidekuni Inadera ◽  
Keyword(s):  
Developmental Delay ◽  
House Dust ◽  
Infant Development ◽  
Developmental Delays ◽  
Frequent Use ◽  
Ages And Stages Questionnaire ◽  
House Dust Allergy ◽  
Vacuum Cleaning ◽  
Reduced Risk

House dust, well known for causing allergy, contains chemicals that are harmful to fetal neurodevelopment. However, whether countermeasures for house dust allergy, such as frequent use of vacuum cleaners, frequent airing of futons, and the usage of anti-mite covers during pregnancy, are related to subsequent reduced risk of infant developmental delay remains unknown. Therefore, we examined this association by analyzing 81,106 mother-infant pairs who participated in a nationwide birth cohort in Japan. Infant developmental delays at 6 and 12 months postpartum were assessed using the Ages and Stages Questionnaire, Third Edition. A generalized linear model analysis was used to derive adjusted odds ratios (AORs) with the lowest care frequency as reference, while controlling 22 covariates. Our analysis showed that the above-mentioned cleaning measures were overall associated with a reduced risk of developmental delays, both at 6 and 12 months postpartum (AOR varied from 0.73 to 0.95, median: 0.84). Additionally, risks tended to decrease with an increase in the cleaning frequency. In conclusion, a negative dose-response association existed between these measures during pregnancy and infant developmental delay. Our results identify a potential role of frequent vacuum cleaning, airing bedding, and usage of anti-mite bedding covers in promoting intact infant development.

scholarly journals Correlation Between Mothers’ Depression and Developmental Delay in Infants Aged 6-18 Months

2015 ◽  
Vol 8 (5) ◽  
pp. 11 ◽  
Author(s):  
Roshanak Vameghi ◽  
Sedigheh Amir Aliakbari ◽  
Homeira Sajjad ◽  
Firoozeh Sajedi ◽  
Hamid Alavimajd
Keyword(s):  
Developmental Delay ◽  
Infant Development ◽  
Unwanted Pregnancy ◽  
Severe Depression ◽  
Medical Sciences ◽  
Problem Solving Skills ◽  
Medical Centers ◽  
Multi Stage ◽  
The Status ◽  
Ages And Stages Questionnaire

<p><strong>BACKGROUND:</strong> Regarding the importance of children’s developmental status and various factors that delay their development, this study was conducted to examine the correlation between mothers’ depression levels and the developmental delay in infants.</p> <p><strong>METHODS:</strong> This descriptive study was performed on 1053 mothers and their infants’ age 6 to18 month-old in medical centers affiliated with Shahid Beheshti University of Medical Sciences, Iran, in 2014-2015. The participants were selected through multi-stage random sampling. The following instruments were used in this study: A demographic and obstetric specification questionnaire, infant specification questionnaire, the Beck Depression Inventory, and the Ages and Stages Questionnaire to determine the status of the children’s development. The data were analyzed using SPSS19 software, Mann-Whitney; independent T-test and logistic-Regression tests were used.</p> <p><strong>RESULTS:</strong> The results showed that 491 mothers<strong> </strong>(46.<strong>7</strong>%)<strong> </strong>suffered mild to extremely severe depression. The delay in infant development was 11.8%. The Mann–Whitney test showed a correlation between mothers’ depression levels and developmental delay in infants (P=0.001). Moreover, there was a significant correlation between mothers’ depression and developmental delays in gross-motor and problem-solving skills (P&lt;0/05). In logistic model age of infants showed significant correlation with developmental delay (P=0.004<strong> </strong>OR=1.07), but unwanted pregnancy, gender of infants, type of delivery and socioeconomic status had no correlation with developmental delay.</p> <p><strong>CONCLUSION:</strong> Given the correlation between mothers’ depression and infant development, it is recommended to screen mothers for depression in order to perform early interventions in developmental delay.</p>

Mindfulness and Parental Stress Among Parents of Children with Developmental Delays: The Role of the Family Environment

2014 ◽  
Author(s):  
Merideth A. Robinson ◽  
Andrea C. Lewallen ◽  
Robyn Finckbone ◽  
Kristin Crocfer ◽  
Keith P. Klein ◽  
...  
Keyword(s):  
Family Environment ◽  
Parental Stress ◽  
Developmental Delays ◽  
The Family

Grape Seeds Extract as Brain Food: A Review

2017 ◽  
Vol 9 (1) ◽  
Author(s):  
Souad El Gengaihi ◽  
Doha H. Abou Baker
Keyword(s):  
Antioxidant Activities ◽  
Complex Mixture ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Seed Extract ◽  
Amyloid Peptide ◽  
Grape Seeds ◽  
Potential Benefits ◽  
Reduced Risk

Interest in the biological role of bioactive compounds present in medicinal herbs has increased over the last years. Of particular interest are plants that have an anti-Alzheimer activities. Several plants can be useful for Alzheimer (AD) management. Such as these which have anti-inflammatory activity, acetylcholinesterase (AChE) inhibitory action, antiapoptotic, slow the aggregation of amyloid peptide and antioxidant activities. Grape seed extract (GSE) is a complex mixture of several compounds, mostly represented by polyphenols and flavonoids. Their consumption is safe and is recognized to exert several health benefits. GS flavonoids have been associated with the reduced risk of chronic diseases, we present some findings on the potential benefits of GSE for the treatment of AD.

Selenium Role in Reproduction, Pregnant/Postpartum Women and Neonates: A Current Study

2020 ◽  
Vol 17 (1) ◽  
pp. 28-37
Author(s):  
Tabinda Sattar
Keyword(s):  
Infant Development ◽  
Selenium Deficiency ◽  
Human Reproduction ◽  
Postpartum Women ◽  
Female Reproduction ◽  
Pregnancy And Lactation ◽  
Males And Females ◽  
One Year ◽  
Selenium Supplements

Background: Selenium is a micronutrient, although required in low amounts, its importance in male and female reproduction is well known. Objectives: The core purpose of this study is to evaluate the role of selenium in human reproduction, during pregnancy/ lactation in women and newborns. The review explains side by side the sources of selenium, required amounts of selenium in humans and during pregnancy or lactation. Methods: Selenium deficiency is a major cause of male infertility. Similarly, selenium deficiency, both in pregnant and postpartum women, would greatly affect the health of the newborn baby in all respects. The effect of maternal selenium upon the fetus and the neonates even one year after birth has been explained with some recent examples. Results: The study elaborates the fact that the selenium deficiency in pregnancy and lactation is common due to fetal/infant development, so selenium supplements must be provided in order to overcome these deficiency symptoms. Conclusions: The better reproductive health in humans is possible due to the sufficient amounts of selenium present both in males and females as well.

scholarly journals Concurrent validity of the Ages and Stages Questionnaire and the Bayley Scales of Infant Development III in China

PLoS ONE ◽  
2019 ◽  
Vol 14 (9) ◽  
pp. e0221675 ◽  
Author(s):  
Ai Yue ◽  
Qi Jiang ◽  
Biaoyue Wang ◽  
Cody Abbey ◽  
Alexis Medina ◽  
...  
Keyword(s):  
Concurrent Validity ◽  
Infant Development ◽  
Ages And Stages Questionnaire ◽  
Bayley Scales

scholarly journals The role of house dust mite immunotherapy in Indonesian children with chronic rhinosinusitis allergy: A randomized control trial

Heliyon ◽  
2021 ◽  
Vol 7 (3) ◽  
pp. e06510
Author(s):  
Azwin Mengindra Putera ◽  
Zahrah Hikmah ◽  
Anang Endaryanto ◽  
Irwanto ◽  
Margarita Maria Maramis
Keyword(s):  
Chronic Rhinosinusitis ◽  
House Dust ◽  
House Dust Mite ◽  
Randomized Control Trial ◽  
Dust Mite ◽  
Randomized Control

scholarly journals Crucial role of stimulator of interferon genes-dependent signaling in house dust mite extract-induced IgE production

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Hiroki Nunokawa ◽  
Yusuke Murakami ◽  
Takashi Ishii ◽  
Tomoya Narita ◽  
Haruyuki Ishii ◽  
...  
Keyword(s):  
B Cell ◽  
House Dust ◽  
House Dust Mite ◽  
Tfh Cells ◽  
Specific Serum ◽  
Mite Extract ◽  
Dust Mite ◽  
Cell Proportion ◽  
House Dust Mite Extract

AbstractStimulator of interferon genes (STING) is a DNA sensor that responds to pathogens and induces type I interferon production. Herein, the role of STING in house dust mite extract (HDM)-induced allergic asthma was investigated. C57BL/6 wild-type (WT) and Sting−/− mice were intratracheally sensitized with HDM, and the bronchoalveolar lavage fluid (BALF), sera, lungs, and mediastinal lymph nodes (MLNs) were analyzed. The total and HDM-specific serum IgE levels were lower in Sting−/− mice than in WT mice. B cell and IgE-positive B cell proportion in BALF and MLNs, respectively, was significantly lower in Sting−/− mice than in WT mice. Additionally, cyclic GMP-AMP, a STING ligand, augmented total and HDM-specific serum IgE levels and B cell proportion in BALF when applied in combination with HDM. To elucidate the role of STING in IgE production, follicular helper T (Tfh) cells, which are involved in B cell maturation, were investigated. Tfh cell proportion in MLNs decreased in Sting−/− mice, and IL-4 and IL-13 production by HDM-restimulated MLN cells from HDM-sensitized mice was decreased in Sting−/− mice compared with WT mice. Thus, STING plays an important role in the maturation and class switching of IgE-producing B cells in allergic inflammation via Tfh cells.

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