scholarly journals Influence of Recurrent Laryngeal Nerve Transient Unilateral Palsy on Objective Voice Parameters and on Voice Handicap Index after Total Thyroidectomy (Including Thyroid Carcinoma)

Author(s):  
Zuzana Veldova ◽  
Richard Holy ◽  
Jan Rotnagl ◽  
Temoore Younus ◽  
Jiri Hlozek ◽  
...  

Introduction: Total thyroidectomy (TT) is one of the most common surgical endocrine surgeries. Voice impairment after TT can occur not only in patients with recurrent laryngeal nerve (RLN) transient paralysis, but also in cases of normal vocal cord mobility. Aim: To compare voice limits using a speech range profile (SRP) in patients before and 14 days after TT and to investigate the influence of the early results of voice quality after TT on the personal lives of patients. We focused on the perception of voice change before and shortly after TT. Materials and methods: A retrospective study, in the period 2018–2020, included 65 patients aged 22–75 years. We compared two groups of patients: group I (n = 45) (without RLN paresis) and group II (n = 20) (with early transient postoperative RLN paresis). Patients underwent video flexible laryngocopy, SRP, and Voice Handicap Index-30 (VHI-30). Results: In group I, the mean values of Fmax (maximum frequency) and Imax (maximum intensity) decreased in women (both p = 0.001), and VHI-30 increased (p = 0.001). In group II after TT in women, the mean Fmax and Imax values decreased (p = 0.005 and p = 0.034), and the frequency range of the voice was reduced from 5 to 2 semitones. The dynamic range of the voice was reduced by 3.4 dB in women and 5.1 dB in men.VHI-30 increased (p = 0.001). Conclusion: The study documented a worsening of the mean values of SRP, VHI-30, and voice parameters of patients in group II. Voice disorders also occurred in group I without RLN paresis. Non-paretic causes can also contribute to voice damage after TT. SRP and VHI-30 are suitable tools for comparing voice status in two groups of patients, including those with dysphonia. Our data support the claim that the diagnosis of a thyroid cancer does not necessarily imply a higher postoperative risk of impaired voice quality for the patient.

2020 ◽  
Vol 6 (2) ◽  
pp. 73-76
Author(s):  
Anurag ◽  
Vishnu Gupta

Background: The thyroid gland is essential for normal growth of the body. This study assessed relation of external branch of superior laryngeal nerve to the superior pole of the thyroid gland. Subjects and Methods: This study was conducted on 25 human cadavers having 50 superior thyroid poles of both genders. Cadavers were classified based on age groups, group I was those with age less than 39 years and group II cadavers were those with age more than 40 years of age. Various measurements were performed on cadavers. Results: 14 cadavers were I group I and 11 were in group II. The mean mass was 67.2 Kgs in group I and 59.5 Kgs in group II, time elapsed after death was 481.5 minutes in group I and 476.4 minutes in group II, mean height was 1.74 meters in group I and 1.69 meters in group II, mean BMI found to be 22.3 kg/m2in group I and 20.1 kg/m2in group II. Height found to be significant between both groups (P< 0.05). The mean distance from EBSLN to cranial point of the thyroid gland was 6.66 mm in group I and 8.96 mm in group II. The mean transverse distance from superior thyroid artery to EBSLN was 3.55 mm in group I and 5.12 mm side in group II. The mean distance of the crossing point between the most cranial point of the thyroid lobe was 6.40 mm in group I and 11.47 mm in group II. The mean distance from the EBSLN to the midline of the neck was 19.80 mm in group I and 18.58 mm in group II. The mean distance from the EBSLN to the midline of the neck on the most cranial point of the cricoid cartilage was 18.77 mm in group I and 17.80 mm in group II. Conclusion: Authors found variation in measurements in left and right side in both group I and group II.


2008 ◽  
Vol 22 (6) ◽  
pp. 617-620 ◽  
Author(s):  
Pongsakorn Tantilipikorn ◽  
Perapun Jareoncharsri ◽  
Siriporn Voraprayoon ◽  
Chaweewan Bunnag ◽  
Peter A. Clement

Background Each ethnic group has different nasal cavity geometries. The reference value of the minimal cross-sectional area (MCA) and the nasal volume (NV) is mandatory for rhinologic evaluation in regular practice and for research. This study was designed to study the normal value of acoustic rhinometry (AR) in Asian subjects in comparison with other ethnic groups. Methods AR was performed in 135 healthy Thai subjects. Subjects were divided into two groups: group I, with normal anterior rhinoscopic appearance; group II included subjects with asymptomatic, slightly deviated nasal septa. Results The mean of the MCA was 0.61 ± 0.60 cm2 before decongestion and 0.64 ± 0.14 cm2 after decongestion. The mean distance from the nostril to the point of MCA (D) was 1.66 ± 0.59 cm before decongestion and 1.41 ± 0.74 cm after decongestion. The mean of the NV measured between 0 and 4 cm was 3.66 ± 0.67 cm3 before decongestion and 4.18 ± 0.75 cm3 after decongestion. Before decongestion, there were no significant differences in the mean of the MCA, D, and NV between group I and group II subjects; however, there were significant differences in mean MCA and NV after decongestion. There were no differences in the parameters between male and female subjects before decongestion, except for the D, but after decongestion the mean values of the MCA, D, and NV were significantly higher in male subjects compared with female subjects. Conclusion The results of this study can be used as a reference value for Asian ethnicities. Thai subjects had measurements comparable with those of the European study and somewhat different from the study in black populations.


2013 ◽  
Vol 127 (10) ◽  
pp. 987-990 ◽  
Author(s):  
S Celebi ◽  
K Yelken ◽  
O N Develioglu ◽  
M Topak ◽  
O Celik ◽  
...  

AbstractObjective:To investigate perceptual, acoustic and aerodynamic voice parameters in obese individuals.Methods:Twenty obese and 20 normal-weight volunteers underwent voice evaluation by laryngoscopy, acoustic analysis, aerodynamic measurement and perceptual analysis (using the grade-roughness-breathiness-asthenia-strain (‘GRBAS') scale and the Voice Handicap Index 10 scale). Data from both subject groups were compared.Results:No difference was found in acoustic analysis parameters between the two groups (p > 0.05). Maximum phonation time in the obese group (mean ± standard deviation, 19.6 ± 4.9 seconds) was significantly shorter than in controls (26.4 ± 4.1 seconds) (p < 0.001), although the s/z ratio was very similar between the two groups. In the obese and control groups, the mean ± standard deviation grade-roughness-breathiness-asthenia-strain scores were 1 ± 1.3 and 0.2 ± 0.6 (p = 0.002) and the mean ± standard deviation Voice Handicap Index 10 scores were 0.5 ± 1.2 and 1.2 ± 1.7 (p = 0.27), respectively.Conclusion:Obese individuals had poorer vocal quality as judged by the grade-roughness-breathiness-asthenia-strain scale, and reduced maximum phonation time. However, there was no change in voice quality as assessed by acoustic analysis and Vocal Handicap Index 10 score, compared with controls.


2000 ◽  
Vol 10 (1) ◽  
pp. 17-23
Author(s):  
Seung Cheol Ahn ◽  
Chae Yong Lee ◽  
Dong Wook Kim ◽  
Moo Hoo Lee

To investigate the short-term vestibular habituation, we performed the 4 successive velocity step tests on 28 volunteers, the peak velocity of which was 100 deg/sec with acceleration and deceleration of 100 deg / sec 2 . As the repeated rotations might alter the vestibulo-ocular reflex (VOR), sinusoidal rotations at a frequency of 0.16 Hz were also given before and after the 4 successive velocity step tests to investigate the changes of gain and phase of VOR. The 28 volunteers were divided into two groups, group I and II, according to their responses to repeated rotations. In group I (25 subjects, mean age 23.7 year), the mean values of the slow cumulative eye position (SCEP), the time integral of eye velocity during nystagmus, was reduced after each trial of the 4-successive velocity step tests as follows; 403.4 ± 29 degree (1st trial), 346.2 ± 37 degree (2nd trial), 278.3 ± 33 degree (3rd trial) and 256.6 ± 36 degree (4th trial). The time constant of the nystagmus was also reduced as follows; 12.9 ± 0.78 second (1st trial), 12 ± 0.63 second (2nd trial), 9.7 ± 0.78 second (3rd trial) and 9.9 ± 0.54 second (4th trial). In group II (3 subjects, mean age 28.3 year), the mean values of SCEP gradually increased; 774.3 ± 135 degree (1st trial), 1127 ± 178 degree (2nd trial), 1096.3 ± 123.4 degree (3rd trial) and 1225.7 ± 199.7 degree (4th trial). The time constant of the nystagmus increased; 15.7 ± 2.7 second (1st trial), 22 ± 4.5 second (2nd trial), 22.3 ± 3.3 second (3rd trial) and 23.3 ± 5.7 second (4th trial). The gain of vestibulo-ocular reflex (VOR) induced by sinusoidal rotations at a frequency 0.16 Hz increased in both groups: 0.59 ± 0.03 to 0.78 ± 0.06 (group I) and 0.65 ± 0.07 to 1.15 ± 0.06 (group II). Phase changes were also observed. In group I, the phase was shifted from 0.6 ± 0.6 degree to − 0.40 ± 0.6 degree. In group II, the phase was shifted from 3.67 ± 1.86 degree to − 0.33 ± 0.33 degree. The repeated rotation did not induce a common nystagmic response in all subjects. Thus, person to person variations should be considered in short term vestibular habituation.


Author(s):  
Joanna Ryniewicz ◽  
Magdalena Orczykowska ◽  
Krzysztof Gronkiewicz ◽  
Małgorzata Pihut

Apart from local lesions, the presence of dental plaque may also have an effect on health, especially in people with general diseases. The aim of this project was to assess the oral hygiene of patients prosthetically treated at the Dental Prosthetics Clinic of the University Dental Clinic in Krakow (Poland) using fixed and removable dentures and to determine the demographic relationships and data related to the education of the respondents. The research material consisted of 120 patients who used fixed (group I) and removable (group II) restorations. Basic dental examinations and oral hygiene examinations were carried out with the use of the API (Approximal Plaque Index) and PI (Plaque Index) plaque indices. This study presents the percentage of respondents in terms of sex, place of residence, and education. The mean PI (plaque index) values were 46.73% (Group I) and 50.05% (Group II). (p = 0.4839). The mean values of API (Approximal Plaque Index) amounted to 65.14% (Group I) and 68.94% (Group II) (p = 0.4695). Patients using dentures showed insufficient oral hygiene, and the hygiene status of patients did not depend on the type of dentures used. The group that is most often treated with prosthetics is women with secondary education. The most numerous group of patients at the Dental Prosthetics Clinic are people living in large cities which results from easier access to health care.


2001 ◽  
Vol 25 (1) ◽  
pp. 13-21 ◽  
Author(s):  
Osmar Aparecido Cuoghi ◽  
Francisco Antonio Bertoz ◽  
Marcos Rogerio de Mendonca ◽  
Eduardo Cesar Almada Santos ◽  
An Tien Li

This study aimed to establish radiographical parameters concerning the tipping, the labiolingual positioning and the angulation of the maxillary permanent incisors in the mixed dentition. Three groups of 20 cephalograms and 20 orthopantomographic radiographs taken from children aging from 7 to 12 years old, with normal occlusion were compared. The Group I presented only the eruption of the central permanent incisors, the Group II presented both the central and lateral permanent incisors and the Group III presented central, lateral incisors and permanent canine teeth. The tipping and the labiolingual positioning were measured, respectively, using U1/PP and U1↔AVERT. Mesiodistally, the angles between the teeth axis and the line that touched the lower border of the orbit in the orthopantomographic radiographs were measured. The mean values of tipping, labiolingual positioning and angulation of the central and lateral incisors obtained from Groups I, II and III were respectively 112°, 1.2mm, 90.4° and 91.7°; 112°, 2.6mm, 89.5° and 96.8° and. 114°, 2.7mm, 87.4° and 92.6°. The tipping levels were similar for all groups, the mean values of the labiolingual positioning were significantly different at 5% when Group I was compared to both Groups II and III.And the mean values of the angulation were significantly different 5% for the central incisors between Groups I and III, and at 1% for the lateral incisors between Groups I and II, and, II and III.


2021 ◽  
Vol 18 (1) ◽  
pp. 7-12
Author(s):  
Md Rabiul Islam ◽  
Tahmina Begum ◽  
Nazrul Islam ◽  
Md Moshabbirul Islam

Background: Recurrent laryngeal nerve is varied anatomically with inferior thyroid artery. Objective: The purpose of the present study was to observe the anatomical variation of recurrent laryngeal nerve with inferior thyroid artery among Bangladeshi people. Methodology: This comparative cross-sectional study was conducted in the Department of Otolaryngology and Head-Neck surgery at Sylhet MAG Osmani Medical College Hospital, Sylhet, Bangladesh from January 2004 to December 2004 for a period of one (01) year. Patients whose recurrent laryngeal nerve was identified during thyroidectomy due to various pathological conditions of thyroid gland were selected as group I. Again, the dead body which were undergone dissection were designated as group II. All the patients whose recurrent laryngeal nerve and inferior thyroid artery were identified during total, near total, sub-total, hemithyroidectomised or lobectomised were included in this study. Result: A total number of 32 patients were recruited for this study. On the left side nerve was found anteriorly in 2(10.53%), in between in 4(21.05%) and posteriorly in 13(68.42%). On the right side-nerve was found anteriorly in 7(30.43%), in between in 6(26.09%) and posteriorly in 10(43.48%). In this series nerve was seen posterior relation more than other two relations and anterior relation more on right side whereas posterior relation on left side, anterior relation more than in between relation on right side but reverse on left side. In group II On the left side nerve was found anteriorly in 2(6.25%), in between in 6(18.75%) and posteriorly in 24(75%). On the right side-nerve was found anteriorly in 8(25%), in between in 9(28.12%), and posteriorly in 10(46.88%). Conclusion: In conclusion each recurrent laryngeal nerve lies posterior to the inferior thyroid artery in the majority of the occasions whereas the nerve lies anterior to the branches of the inferior thyroid artery less commonly except right side of both study group. Journal of Science Foundation, January 2020;18(1):7-12


2020 ◽  
Vol 100 (12) ◽  
pp. 2198-2204
Author(s):  
Qing Yi Lu ◽  
Bin Zhang ◽  
Ke Xin Jin ◽  
Wan Ling Jiang ◽  
Xiang Li ◽  
...  

Abstract Objective Unilateral vocal fold paralysis (UVFP) can be caused by iatrogenic injury or tumor-induced damage to the recurrent laryngeal nerve. Studies of comprehensive rehabilitation therapies for patients suffering from severe UVFP are limited. The purpose of this case report is to describe an improvement in complete aphonia after comprehensive rehabilitation therapies in a patient with severe UVFP due to a lung tumor. Methods An 81-year-old woman with a history of bronchial adenoma had complete aphonia due to compression of the left recurrent laryngeal nerve by the tumor. Dynamic fibrolaryngoscope revealed paralysis of the left vocal fold. The patient was treated with interferential current therapy, vocal training, and kinesiology taping. Indicators of voice recovery were scored according to the grade, roughness, breathiness, asthenia, strain scale, and the voice handicap index. Results After 10 days of comprehensive rehabilitation treatment, the patient recovered from complete aphonia to normal communication. The hoarseness and breathiness of patient were significantly improved. In addition, the grade, roughness, breathiness, asthenia, strain, and the voice handicap index scores changed from severe to mild or absent. Conclusion This case provided a novel comprehensive treatment for a patient with UVFP, which was safe, cost-effective, and easy to implement in clinic.


2021 ◽  
Vol 15 (5) ◽  
pp. 1127-1129
Author(s):  
A. R. Memon ◽  
M. Akram ◽  
U. Bhatti ◽  
A. S. Khan ◽  
K. Rani ◽  
...  

Background: Vitamin B3 (Niacin) is known to decrease LDL‐cholesterol, and triglycerides, and increase HDL‐cholesterol levels. The evidence of benefits with niacin monotherapy or add‐on to statin‐based therapy is controversial. Aim: To determine the effects of vitamin B3 with statins on lipid profile of patients of angina pectoris with dyslpidemia. Study Design: Randomized control trial study. Place and Duration of Study: Department of Biochemistry, Shaikha Fatima Institute of Nursing & Health Sciences (SFINHS), Lahore with collaboration of Cardiology OPD of Shaikh Zayed Hospital Lahore from 1st November 2019 to 31st January 2020. Methodology: Seventy four diagnosed cases of angina pectoris with dyslipidemia were recruited with age range from 30 to 50 years. They were divided into two groups; Group I contained 36 patients as controlled group which was given treatment of angina with Tab. Rovista (statin) 10mg at dinner for treatment of dyslipidemia and Group II contained 38 patients as case study group which was given treatment of angina with Tab. Rovista (statin) 10 mg at dinner and tablet Vitamin B3 500 mg with single OD dose at day time for treatment of dyslipidemia for 8 weeks. Results: The mean serum cholesterol levels at zero level (before the start of treatment) of group I was 244 mg/dl and group II was 246 mg/dl, LDL of group I was 169 mg/dl while group II was 170 mg/dl and HDL of group I was 20 mg/dl while group II was 19 mg/dl . After the treatment group I which taken only statins for treatment of dyslipidemia the mean serum cholesterol levels was 210 mg/dl, LDL was 144 mg/dl and HDL was 26 mg/dl while the mean values of group II (taken statin as well as vitamin B3) serum cholesterol level was 192 mg/dl, LDL was 122 mg/dl and HDL was 44 mg/dl. The results shown there were significant effects of statin therapy along with vitamin B3 on serum LDL and serum HDL levels. Conclusion: There were significant effects of statin therapy along with vitamin B3 on serum LDL and Serum HDL levels. Key Words: Vitamin B3, Serum Cholesterol, Serum LDL &HDL


2003 ◽  
Vol 50 (3) ◽  
pp. 154-175 ◽  
Author(s):  
Mile Ignjatovic ◽  
Vladimir Cuk ◽  
Andjela Ozegovic ◽  
Snezana Cerovic ◽  
Zoran Kostic ◽  
...  

Background/Aims. Thyroid gland surgery today is not saddled with high incidence of main complications. Miscellaneous surgical institutions with different surgical approach, operative technique and radicality have published reports with great discrepancy in incidence of complications, analyzing them with different methods of diagnosis and result evaluation. In the same way it is well known that higher latitude of operative procedure gave better control of thyroid diseases, but it can be accompanied with more complications. All of that motivate us to analyze complications of operative treatment in our patients under well known criteria, with hypothesis that higher radicality of operative procedure do not increase incidence of complications, and that this incidence is in correlations with results published in world literature. Aim of this nonrandomized study was to analyze results of operative treatment for huge number of consecutively operated patients in our teaching hospital, to analyze and compare results according to group of diseases and operative procedures, and to compare final results with results published in the world literature. Methods. Complications of operative treatment were analyzed retrospectively for period 1988-1997 (Group I) and prospectively in period 1998-2002 (Group II). Operations were performed by 20 surgeons and 20 young surgeons during their education. We have analyzed only complications during first 30 days after operation. Results. In Group I there was 1425 patients with 1451 operations (192 thyroid malignances, 247 hyperthireosis, 98 reoperations, 13% thyreoidectomies and 14,8% lobectomies), with complication rate of 14,3%. Most common complication was recurrent laryngeal nerve injury in 9,3% patients or 6,3% according to number of exposed nerves (?nerve at risk?), then postoperative hypocalcemia with rate of 4,7% (persistent in 1,3%). In Group II in 675 patients there was 687 operations (96 thyroid malignances, 111 hyperthireosis, 35 reoperations, 36,6% thyreoidectomies and 25% lobectomies), with complication rate of 10,7%. Most common postoperative complication was hypocalcemia with 5% rate (persistent in 0,7%), then recurrent laryngeal nerve injury in 4,4% patients or 2,9% according to number of exposed nerves (?nerve at risk?). Incidence of recurrent laryngeal nerve injury in Group II is less frequent than in Group I, highly statistically significant (p<0,01), while for other complications there is no statistically significant difference. Totally for both groups there was 0,7% tracheotomies, postoperative bleeding in 1,1% of patients, wound haemathoma in 0,5%, wound infections in 0,9%, pneumonia in 0,5%, mortality 0,5% and most common cause of death (8/11) was problem with respiration, ?Airway obstruction?. In Group II complications were less frequent in total thyreoidectomies in relation to lobectomy with contra lateral subtotal lobectomy. In both groups and totally incidence of complications was higher in reoperations, in patients with more extensive operative procedure, in malignant diseases and hyperthyreosis. Conclusion. In thyroid gland surgery more extensive operative treatment with improved operative technique (micro dissection, recurrent laryngeal nerve visualization and parathyroid gland preservation), in our teaching hospital, do not have influence on incidence of postoperative complications, even recurrent laryngeal nerve injury was significantly less frequent. This results are in correlation with published results of similar hospitals around the world.


Sign in / Sign up

Export Citation Format

Share Document