scholarly journals Pre-Hypertension and Its Determinants in Healthy Young Adults: Analysis of Data from the Korean National Health and Nutrition Examination Survey VII

Author(s):  
Insil Jang

The purpose of this cross-sectional study was to identify risk factors in the normotensive and pre-hypertensive group based on the blood pressure results of healthy young adults from the Korean National Health and Nutrition Examination Survey 2018. The participants were 2225 healthy young adults between the ages of 19 and under 45, excluding those with a diagnosis of hypertension or taking antihypertensive medications. Of the 2225 participants, the normotensive group was 1498 (67.3%) and the pre-hypertensive group 727 (32.7%). Determinants of pre-hypertension were analyzed using multiple logistic regression based on a complex sample design. Factors related to pre-hypertension in young adults were age, smoking, waist circumference, diabetes, anemia, cholesterol levels including HDL cholesterol, and uric acid levels. Pre-hypertension is a pre-stage that can prevent the morbidity of hypertension through lifestyle control, so its management is very important. Furthermore, a young adult is a stage in the growth and development of human beings, in which lifestyles such as healthy behaviors, eating habits, and exercise are fixed. Therefore, it is very important to improve lifestyles such as diet, exercise, and smoking cessation and to control risk factors in young adults who are at the pre-hypertension stage for health promotion. Continuous health examinations should be conducted for young adults, and education that can be practiced based on clinical data through this should be implemented for community health.

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Heli Ghandehari ◽  
Sachin Kamal-Bahl ◽  
Nathan D Wong

Background: Recent U.S. population data are lacking regarding the achievement of recommended lipid levels according to demographic factors and comorbidities. We evaluated the extent of LDL-C, HDL-C, triglyceride, and overall lipid goal attainment in U.S. adults. Design, Setting, and Participants: Data analysis from adults aged ≥20 who had fasted for ≥8 hours (n=2987 representing 132.7 million) in the National Health and Nutrition Examination Survey 2003–2004, a representative cross-sectional survey of the non-institutionalized civilian U.S. population. Main Outcome Measures: The proportion of adults at recommended levels for LDL-C, HDL-C, triglycerides, and all lipids were examined by gender, age, ethnicity and the presence of cardiovascular disease (CVD), diabetes (DM) or metabolic syndrome (MetS). Goals were <100 mg/dl for LDL-C for DM, CVD, or 2+ risk factors and >20% 10-year risk for coronary heart disease (CHD), <130 mg/dl if 2+ risk factors and ≤20% 10-year risk for CHD, or <160 mg/dl if <2 risk factors; ≥40 mg/dl (male) or ≥50 mg/dl (female) for HDL-C; and <150 mg/dl for triglycerides. Results: The proportion at goal for LDL-C was 74.5%, HDL-C 73.2%, triglycerides 73.6%, and 47.5% for all lipids. Control of LDL-C and triglycerides was greater in females, and HDL-C greater in males. Mexican-Americans and persons with CVD, DM, or MetS were least likely to be at recommended levels (see Table ). Table . Proportion (%) of US adults 2003–2004 at recommended levels for LDL-C, HDL-C, triglycerides, and all lipids Conclusions: While three-fourths of U.S. adults are at recommended levels for LDL-C, HDL-C and triglycerides individually, less than half are at goal for all lipids. For persons with DM or CVD, only a third are at goal for LDL-C and only a sixth are at goal for all lipids. Improved treatment efforts to optimize goal attainment of all lipids are required.


2021 ◽  
Author(s):  
Sunggun Lee ◽  
Min Wook So ◽  
Doo-Ho Lim ◽  
Mi-Young Kim ◽  
Jae-Ha Lee ◽  
...  

Abstract Objective As heritability of hyperuricemia remains largely unexplained, we analyzed the association between parental and offspring hyperuricemia at the phenotype level. Methods This cross-sectional study included data on 2373 offspring and both-parent pairs from the 7th Korean National Health and Nutrition Examination Survey. Logistic regression and generalized estimating equation analysis were used to evaluate the association between offspring and parental hyperuricemia adjusting for metabolic risk factors and alcohol intake. Results Both maternal and paternal hyperuricemia were associated with offspring hyperuricemia among teenagers, but from age of 20 years, a strong association was observed between offspring and paternal, rather than, maternal hyperuricemia, and this could not be explained by metabolic risk factors such as obesity. However, there was positive interaction between offspring alcohol intake and parental hyperuricemia, and there was a stronger association between terciles of offspring alcohol intake and hyperuricemia in the presence of parental hyperuricemia: T1 (reference), T2 OR 1.1 (0.3–4.6), and T3 OR 3.3 (1.4–7.9) (P for trend 0.017) vs. T1 (reference), T2 OR 0.7 (0.3–1.9), and T3 OR 1.1 (0.6–2.2) (P for trend 0.974). Conclusion These results suggest gene-environment interaction, especially with respect to alcohol intake for hyperuricemia in Korean adults.


2019 ◽  
Vol 31 (5) ◽  
pp. 404-412 ◽  
Author(s):  
Deulle Min ◽  
Eunhee Cho

We included 11 298 subjects aged 30 years or older without diagnosis of diabetes by doctors who had undergone A1C screening. The diagnostic criterion for diabetes was A1C ≥6.5% (48 µmol/mol). This cross-sectional study was performed by reflecting weight of the sample in Korean National Health and Nutrition Examination Survey to represent South Korea. Risk factors were age (odds ratio [OR] = 1.06, 95% confidence interval [CI] = 1.04-1.08), Medicaid beneficiary (OR = 2.77, 95% CI = 1.25-6.14), presence of family history of diabetes (OR = 1.97, 95% CI = 1.36-2.84), serum triglyceride level (OR = 1.01, 95% CI = 1.01-1.03), serum high-density lipoprotein level (OR = 0.96, 95% CI = 0.95-0.98), currently smoking (OR = 1.85, 95% CI = 1.20-2.85), and the presence of regular checkup (OR = 1.41, 95% CI = 1.01-2.00). To prevent diabetes with a healthy life, it is necessary to establish a diabetes prevention program for vulnerable people and implement health-related policies such as smoking cessation and regular checkups.


BMJ Open ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. e028652 ◽  
Author(s):  
Chunli Bi ◽  
Lijuan Wang ◽  
Chong Sun ◽  
Mengzi Sun ◽  
Pingping Zheng ◽  
...  

ObjectiveTraditionally, the absence of insulin resistance risk factors (IRRFs) was considered a low risk for insulin resistance (IR). However, IR also existed in certain individuals without IRRFs; thus this study aims to explore predictors of IR targeted at the population without IRRFs.DesignCross-sectional survey.SettingNational Health and Nutrition Examination Survey.ParticipantsParticipants without regular IRRFs (IRRF-Free, n=2478) and a subgroup without optimal IRRFs (IRRF-Optimal, n=1414) were involved in this study.Primary and secondary outcome measureIRRFs and the optimal cut-off value of triglyceride (TG) to predict IR.ResultsOverall, the prevalence of IR was 6.9% and 5.7% in the IRRF-Free group and the IRRF-Optimal group, respectively. TG and waist circumference were independently associated with the prevalence of IR in both the groups (OR=1.010 to 10.20; p<0.05 for all), where TG was positively associated with IR. The area under the receiver operating characteristic curve of TG was 0.7016 (95% CI: 0.7013 to 0.7018) and 0.7219 (95% CI: 0.7215 to 0.7222), and the optimal cut-off value of TG to predict IR was 79.5 mg/dL and 81.5 mg/dL in the IRRF-Free group and the IRRF-Optimal group, respectively.ConclusionThere is an association between TG and IR even in the normal range of TG concentration. Therefore, normal TG could be used as an important indicator to predict the prevalence of IR in the absence of IRRFs.


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