scholarly journals The Impact of MNRI Therapy on the Levels of Neurotransmitters Associated with Inflammatory Processes

2020 ◽  
Vol 21 (4) ◽  
pp. 1358 ◽  
Author(s):  
Tatiana V. Tatarinova ◽  
Trina Deiss ◽  
Lorri Franckle ◽  
Susan Beaven ◽  
Jeffrey Davis
Keyword(s):  
Attention Deficit ◽  
Attention Deficit Disorder ◽  
Emotional Regulation ◽  
Cognitive Skills ◽  
Developmental Disorders ◽  
Negative Impact ◽  
Autism Spectrum ◽  
Post Traumatic Stress ◽  
Compulsive Disorder ◽  
The Impact

The neurotransmitter levels of representatives from five different diagnosis groups were tested before and after participation in the MNRI®—Masgutova Neurosensorimotor Reflex Intervention. The purpose of this study was to ascertain neurological impact on (1) Developmental disorders, (2) Anxiety disorders/OCD (Obsessive Compulsive Disorder), PTSD (Post-Traumatic Stress disorder), (3) Palsy/Seizure disorders, (4) ADD/ADHD (Attention Deficit Disorder/Attention Deficit Disorder Hyperactive Disorder), and (5) ASD (Autism Spectrum Disorder) disorders. Each participant had a form of neurological dysregulation and typical symptoms respective to their diagnosis. These diagnoses have a severe negative impact on the quality of life, immunity, stress coping, cognitive skills, and social assimilation. This study showed a trend towards optimization and normalization of neurological and immunological functioning, thus supporting the claim that the MNRI method is an effective non-pharmacological neuromodulation treatment of neurological disorders. The effects of MNRI on inflammation have not yet been assessed. The resulting post-MNRI changes in participants’ neurotransmitters show significant adjustments in the regulation of the neurotransmitter resulting in being calmer, a decrease of hypervigilance, an increase in stress resilience, behavioral and emotional regulation improvements, a more positive emotional state, and greater control of cognitive processes. In this paper, we demonstrate that the MNRI approach is an intervention that reduces inflammation. It is also likely to reduce oxidative stress and encourage homeostasis of excitatory neurotransmitters. MNRI may facilitate neurodevelopment, build stress resiliency, neuroplasticity, and optimal learning opportunity. There have been no reported side effects of MNRI treatments.

scholarly journals Behavioral and Emotional Disorders in Children and Their Anesthetic Implications

Children ◽  
2020 ◽  
Vol 7 (12) ◽  
pp. 253
Author(s):  
Srijaya Reddy ◽  
Nina Deutsch
Keyword(s):  
Emotional Disorders ◽  
Autism Spectrum ◽  
Hospital Environment ◽  
Post Traumatic Stress ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Oppositional Defiant ◽  
Post Traumatic ◽  
Perioperative Course ◽  
The Impact

While most children have anxiety and fears in the hospital environment, especially prior to having surgery, there are several common behavioral and emotional disorders in children that can pose a challenge in the perioperative setting. These include anxiety, depression, oppositional defiant disorder, conduct disorder, attention deficit hyperactivity disorder, obsessive compulsive disorder, post-traumatic stress disorder, and autism spectrum disorder. The aim of this review article is to provide a brief overview of each disorder, explore the impact on anesthesia and perioperative care, and highlight some management techniques that can be used to facilitate a smooth perioperative course.

Self-Report and Objective Measures of ADHD-Related Behaviors in Parents of Preschool Children at Risk for ADHD

CNS Spectrums ◽  
2004 ◽  
Vol 9 (9) ◽  
pp. 639-647 ◽  
Author(s):  
Elizabeth A. Curko Kera ◽  
David J. Marks ◽  
Olga G. Berwid ◽  
Amita Santra ◽  
Jeffrey M. Halperin
Keyword(s):  
At Risk ◽  
Preschool Children ◽  
Cognitive Processing ◽  
Attention Deficit ◽  
Attention Deficit Disorder ◽  
Performance Test ◽  
Negative Impact ◽  
Reaction Times ◽  
Self Report ◽  
Significant Group

ABSTRACTObjective: Few studies have used a combination of objective and self-report measures to examine neuropsychological and behavioral functioning in parents of children with attention-deficit/hyperactivity disorder (ADHD). This study examined attention and inhibitory control in the parents of preschool children who were rated as “at risk” for developing ADHD as compared with parents of controls.Methods:Preschool children (N=53) were divided into at risk for ADHD and control groups based on parent and teacher ratings of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition ADHD symptoms. One parent of each child was administered an identical pairs Continuous Performance Test (CPTIP), a Go/No-Go task, and the Brown Attention-Deficit Disorder Scale for Adults.Results: Parents of preschoolers at risk for ADHD showed a pattern of responding on measures of vigilance characterized by slower reaction times and increased commission errors as compared with parents of controls. There were no significant group differences on self-report measures on the Brown Attention-Deficit Disorder Scale for Adults.Conclusion: Parents of preschoolers at risk for ADHD appear to exhibit cognitive processing deficits that may not be evident using self-report measures. Further research is needed to more clearly identify the specific nature of these neuropsychological deficits and to determine whether they have a negative impact on their children.

scholarly journals How to Predict the Impact of Methylphenidate on Cardiovascular Risk in Children with Attention Deficit Disorder: Methylphenidate Improves Autonomic Dysfunction in Children with ADHD

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Reiner Buchhorn ◽  
Christian Müller ◽  
Christian Willaschek ◽  
Kambiz Norozi
Keyword(s):  
Sudden Cardiac Death ◽  
Attention Deficit ◽  
Attention Deficit Disorder ◽  
Cardiac Death ◽  
Control Group ◽  
Healthy Children ◽  
Children With Adhd ◽  
Heart Defect ◽  
Adhd Children ◽  
The Impact

Background. Although stimulants have long been touted as treatments for attention deficit disorder with or without hyperactivity (ADHD), in recent years, increasing concerns have been raised about the cardiovascular safety of these medications. We aimed to prove if measurements of autonomic function with time domain analysis of heart rate variability (HRV) in 24-hour Holter ECG are useful to predict the risk of sudden cardiac death in ADHD children and adolescents. Methods. We analysed HRV obtained from children with the diagnosis of ADHD prior to (N=12) or during medical therapy (N=19) with methylphenidate (MPH), aged 10.8±2.0 years (mean ± SD), who were referred to our outpatient Paediatric Cardiology Clinic to rule out heart defect. As a control group, we compared the HRV data of 19 age-matched healthy children without heart defect. Results. Average HRV parameters from 24-hour ECG in the ADHD children prior to MPH showed significant lower values compared to healthy children with respect to rMSSD (26±4 ms versus 44±10 ms, P≤0.0001) and pNN50 (6.5±2.7% versus 21.5±9.0%, P≤0.0001). These values improved in MPH-treated children with ADHD (RMSSD: 36±8 ms; pNN50: 14.2±6.9%). Conclusion. Children who suffer from ADHD show significant changes in HRV that predominantly reflects diminished vagal tone, a well-known risk factor of sudden cardiac death in adults. In our pilot study, MPH treatment improved HRV.

scholarly journals ENIGMA and Global Neuroscience: A Decade of Large-Scale Studies of the Brain in Health and Disease across more than 40 Countries

2019 ◽  
Author(s):  
Paul Thompson ◽  
Neda Jahanshad ◽  
Christopher R. K. Ching ◽  
Lauren Salminen ◽  
Sophia I Thomopoulos ◽  
...  
Keyword(s):  
Large Scale ◽  
Meta Analysis ◽  
22Q11.2 Deletion Syndrome ◽  
Autism Spectrum ◽  
Deletion Syndrome ◽  
Sex And Gender ◽  
Post Traumatic Stress ◽  
Global Alliance ◽  
Compulsive Disorder ◽  
Health And Disease

This review summarizes the last decade of work by the ENIGMA (Enhancing NeuroImaging Genetics through Meta Analysis) Consortium, a global alliance of over 1,400 scientists across 43 countries, studying the human brain in health and disease. Building on large-scale genetic studies that discovered the first robustly replicated genetic loci associated with brain metrics, ENIGMA has diversified into over 50 working groups (WGs), pooling worldwide data and expertise to answer fundamental questions in neuroscience, psychiatry, neurology, and genetics. Most ENIGMA WGs focus on specific psychiatric and neurological conditions, other WGs study normal variation due to sex and gender differences, or development and aging; still other WGs develop methodological pipelines and tools to facilitate harmonized analyses of “big data” (i.e., genetic and epigenetic data, multimodal MRI, and electroencephalography data). These international efforts have yielded the largest neuroimaging studies to date in schizophrenia, bipolar disorder, major depressive disorder, post-traumatic stress disorder, substance use disorders, obsessive-compulsive disorder, attention-deficit/hyperactivity disorder, autism spectrum disorders, epilepsy, and 22q11.2 deletion syndrome. More recent ENIGMA WGs have formed to study anxiety disorders, suicidal thoughts and behavior, sleep and insomnia, eating disorders, irritability, brain injury, antisocial personality and conduct disorder, and dissociative identity disorder. Here, we summarize the first decade of ENIGMA’s activities and ongoing projects, and describe the successes and challenges encountered along the way. We highlight the advantages of collaborative large-scale coordinated data analyses for testing reproducibility and robustness of findings, offering the opportunity to identify brain systems involved in clinical syndromes across diverse samples and associated genetic, environmental, demographic, cognitive and psychosocial factors.

How Microaggressions Are Harmful

2020 ◽  
pp. 43-56
Author(s):  
Monnica T. Williams
Keyword(s):  
Mental Health ◽  
Negative Impact ◽  
Somatic Symptoms ◽  
Mental Health Issue ◽  
Post Traumatic Stress ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Implicit Biases ◽  
Post Traumatic ◽  
Everyday Discrimination

Abstract: This chapter discusses the research regarding microaggressions and negative mental health outcomes. Microaggressions are associated with increased stress, increased physical ailments such as hypertension and impaired immune responses, increased depression and depressive symptoms, lower self-esteem and self-efficacy, increased alcohol abuse and binge drinking, substance use disorders, increased post-traumatic stress disorder symptoms, higher levels of suicidal ideation, increased anxiety, increased somatic symptoms and negative affect, and increased obsessive–compulsive disorder symptoms. Overall, those who experience everyday discrimination have higher odds of any lifetime mental health issue. This is illustrated using a case example of a student who developed depression and anxiety from experiencing microaggressions in school, leading to a negative impact on mental health. The chapter presents an example interaction between a client and a therapist illustrating that microaggressions can be harmful to White people as well in indirect ways. Furthermore, to address mental health disparities and treatment barriers as a result of various pathways including microaggressions, clinicians need to address their own possible implicit biases that can lead to perpetuating these problems.

Resilience Training as a Complementary Treatment for PTSD

2016 ◽  
Author(s):  
Robin L. Toblin ◽  
Amy B. Adler
Keyword(s):  
Emotional Regulation ◽  
Cognitive Skills ◽  
Positive Outcome ◽  
Relationship Building ◽  
Post Traumatic Stress ◽  
Research Areas ◽  
Evidence Based Treatments ◽  
The Face ◽  
Resilience Training ◽  
Self Examination

Resilience can be viewed as a process in which behaviors or attitudes can lead to a more positive outcome in the face of a traumatic stressor. Universal and targeted resilience training programs (e.g., primary and secondary prevention programs) can be adapted to complement evidence-based treatments (EBTs) for post-traumatic stress disorder (PTSD), tertiary interventions. Using a skill-focus for resilience may increase optimism and self-efficacy for individuals, and therefore, their engagement in the homework and self-examination required by EBTs. Resilience topics that seem especially fitting as an adjunct for treatment are (1) optimism, (2) relationship building, (3) cognitive skills, (4) energy management, (5) emotional regulation, and (6) PTG. The changes necessary for modifying content designed for a primary prevention audience, several group therapy considerations, and the timing of resilience training relative to EBTs are elucidated. Potential research areas are discussed.

Diagnosis and Epidemiology of Pediatric Psychiatric Disorders

2017 ◽  
Author(s):  
Elise B. Robinson ◽  
Benjamin M. Neale ◽  
Mark J. Daly
Keyword(s):  
Pervasive Developmental Disorders ◽  
Developmental Disorders ◽  
Autism Spectrum ◽  
Tic Disorders ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Diagnostic Categories ◽  
Severe Impairment ◽  
Substance Abuse Disorders ◽  
Definition Of

Pediatric psychiatric conditions are rising in estimated prevalence, and these disorders place an enormous burden on parents, educators, and the health care system. This rise in prevalence likely contains elements of diagnostic changes, greater awareness of these disorders, and true changes in incidence. It has been estimated that there is nearly a 50% lifetime childhood prevalence of one or more mood, anxiety, or behavioral disorders (excluding eating and substance abuse disorders) and that more than 20% of children meet the definition of severe impairment. This chapter focuses on epidemiology, heritability, and implied genetic architecture in representative pediatric neuropsychiatric conditions. We consider five major diagnostic categories and highlight major diagnosis within each, specifically, intellectual disability, pervasive developmental disorders (autism spectrum disorder [ASD]), hyperactive and inattentive behavior (attention deficit/hyperactivity disorder [ADHD]), obsessive compulsive disorder (OCD) and tic disorders (TD) (which includes Tourette Syndrome [TS] and other chronic tic disorders).

ASD, OCD and violence – a forensic case study

2020 ◽  
Vol 11 (1) ◽  
pp. 1-8
Author(s):  
Holly Edwards ◽  
Lorraine Higham
Keyword(s):  
Emotional Regulation ◽  
Aggressive Behaviour ◽  
Psychological Treatment ◽  
Autism Spectrum ◽  
Complex Case ◽  
Obsessive Compulsive ◽  
Content Type ◽  
Compulsive Disorder ◽  
Offending Behaviour

Purpose The purpose of this paper is to illustrate the formulation and psychological treatment of a complex case whereby a combination of autism spectrum disorder (ASD) and obsessive compulsive disorder (OCD) has resulted in violent and aggressive behaviour. Design/methodology/approach This paper provides a brief summary of literature in relation to ASD, OCD and risk-offending behaviour followed by a case study of a man (referred to as “John”) with a diagnosis of ASD and OCD who has an extensive history of institutional violence and aggressive behaviour. Findings This paper highlights the complexity of a case that may support research suggesting that impaired theory of mind, poor emotional regulation and problems with moral reasoning increase the risk of an individual with ASD engaging in violence, in addition to a comorbidity of ASD and OCD resulting in a more severe and treatment-resistant form of OCD. Originality/value This paper highlights the challenges faced when working with a patient with Asperger’s syndrome and OCD with entrenched beliefs that lead to the use of violence as a compulsion to temporarily overcome unpleasant thoughts related to low self-esteem.

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