scholarly journals How to Predict the Impact of Methylphenidate on Cardiovascular Risk in Children with Attention Deficit Disorder: Methylphenidate Improves Autonomic Dysfunction in Children with ADHD

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Reiner Buchhorn ◽  
Christian Müller ◽  
Christian Willaschek ◽  
Kambiz Norozi
Keyword(s):  
Sudden Cardiac Death ◽  
Attention Deficit ◽  
Attention Deficit Disorder ◽  
Cardiac Death ◽  
Control Group ◽  
Healthy Children ◽  
Children With Adhd ◽  
Heart Defect ◽  
Adhd Children ◽  
The Impact

Background. Although stimulants have long been touted as treatments for attention deficit disorder with or without hyperactivity (ADHD), in recent years, increasing concerns have been raised about the cardiovascular safety of these medications. We aimed to prove if measurements of autonomic function with time domain analysis of heart rate variability (HRV) in 24-hour Holter ECG are useful to predict the risk of sudden cardiac death in ADHD children and adolescents. Methods. We analysed HRV obtained from children with the diagnosis of ADHD prior to (N=12) or during medical therapy (N=19) with methylphenidate (MPH), aged 10.8±2.0 years (mean ± SD), who were referred to our outpatient Paediatric Cardiology Clinic to rule out heart defect. As a control group, we compared the HRV data of 19 age-matched healthy children without heart defect. Results. Average HRV parameters from 24-hour ECG in the ADHD children prior to MPH showed significant lower values compared to healthy children with respect to rMSSD (26±4 ms versus 44±10 ms, P≤0.0001) and pNN50 (6.5±2.7% versus 21.5±9.0%, P≤0.0001). These values improved in MPH-treated children with ADHD (RMSSD: 36±8 ms; pNN50: 14.2±6.9%). Conclusion. Children who suffer from ADHD show significant changes in HRV that predominantly reflects diminished vagal tone, a well-known risk factor of sudden cardiac death in adults. In our pilot study, MPH treatment improved HRV.

scholarly journals The Impact of Neurofeedback on Clinical Signs of Children That Have Attention Deficit Disorder and Hyperactivity

2017 ◽  
Vol 9 (2) ◽  
pp. 48
Author(s):  
Samaneh Hedayati Manesh ◽  
Azam Alikhademi
Keyword(s):  
Attention Deficit ◽  
Attention Deficit Disorder ◽  
Clinical Signs ◽  
The Other ◽  
Control Group ◽  
Wait List ◽  
Other Hand ◽  
Adhd Children ◽  
The Impact ◽  
Experimental Group

This study was an attempt to examine the impact of Neurofeedback on clinical signs of Children that have attention deficit disorder and hyperactivity. The participants of this study 24 boys (6-11) that afflicted to ADHD. The participants of the study randomly divided into two groups and were selected to participate in the study. The experimental group received the Neurofeedback treatment (8 weeks, three sessions in a week). The control group, on the other hand was placed in a wait list. After treatment, CBCL, IVA, QEEG were administered between two groups. The analysis of data revealed that Nero feedback has a significant impact on ADHD children. Moreover, Neurofeedback treatment leads to improve attention deficit disorder and decrease impulsivity in ADHD children.

scholarly journals Comparison of Nutrients' Intakes in Children with and without Attention Deficit Hyperactivity Disorder

2020 ◽  
Author(s):  
Elham Shareghfarid ◽  
Zohreh Sadat Sangsefidi ◽  
Mahdieh Hosseinzadeh ◽  
Amin Salehi-Abargouei ◽  
Mohammad Mohammadi
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Control Group ◽  
Healthy Children ◽  
Dietary Intakes ◽  
Children With Adhd ◽  
Hyperactivity Disorder ◽  
Adhd Children ◽  
Calcium Magnesium ◽  
Control Survey

Background: Attention deficit hyperactivity disorder (ADHD) is the most common chronic mental disorder among children. Children with ADHD may be at risk for a variety of nutrients' deficiencies. We aimed to assess the nutrients' intakes among ADHD children and compare them with the healthy ones. Methods: This was a hospital-based case-control survey over 120 ADHD as the cases and 240 non-ADHD children as the control participants aged 6-13 years. Usual dietary intakes were assessed using a validated semi quantitative food-frequency questionnaire (FFQ). The P-values were considered significant if they were < 0·05. Results: Energy: 2812.2 ± 1029.9 kcal/day vs. 3136.4 ± 1360.3 kcal/day, P = 0.001), fat: 78.3 ± 28.8 g/day vs. 87.2 ± 44.9 g/day, P > 0.001), and carbohydrate: 436.8 ± 192.6 g/day vs. 479.9 ± 244.2 g/day, P = 0.009) intakes were significantly lower in ADHD than healthy children. Similarly, consumption of calcium: 968.5 ± 358.3 mg/day vs. 1055.7 ± 453.4 mg/day, P = 0.03) and magnesium: 363.1 ± 173.9 mg/day vs. 411.9 ± 220.8 mg/day, P = 0.01) were significantly lower in the cases than control group. However, intakes of thiamin: 34.4±18.8 mg/day vs. 40.4 ± 25.6 mg/day, P = 0.002), riboflavin: 1.99 ± 0.76 mg/day vs. 2.21 ± 0.95 mg/day, P = 0.01), niacin: 24.9 ± 10.6 mg/day vs. 27.5 ± 13.2 mg/day, P = 0.01), and vitamin B5: 6.85 ± 3.35 mg/day vs. 7.49 ± 3.84 mg/day, P = 0.02) were significantly lower in the case than control group. Conclusion: Children with ADHD consumed significantly lower quantities of energy, macronutrients, calcium, magnesium, B vitamins (B1, B2, B3, B5), and vitamin C compared with the healthy children.

scholarly journals Attention-deficit/hyperactivity disorder: the impact of methylphenidate on working memory, inhibition capacity and mental flexibility

2017 ◽  
Vol 75 (4) ◽  
pp. 204-208 ◽  
Author(s):  
Cristiana Bolfer ◽  
Sandra Pasquali Pacheco ◽  
Miriam Harumi Tsunemi ◽  
Walter Souza Carreira ◽  
Beatriz Borba Casella ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Working Memory ◽  
Attention Deficit ◽  
Digit Span ◽  
Control Group ◽  
Hyperactivity Disorder ◽  
Mental Flexibility ◽  
Adhd Children ◽  
Memory Inhibition ◽  
The Impact

ABSTRACT Objective To compare children with attention-deficit/hyperactivity disorder (ADHD), before and after the use of methylphenidate, and a control group, using tests of working memory, inhibition capacity and mental flexibility. Methods Neuropsychological tests were administrated to 53 boys, 9–12 years old: the WISC-III digit span backward, and arithmetic; Stroop Color; and Trail Making Tests. The case group included 23 boys with ADHD, who were combined type, treatment-naive, and with normal intelligence without comorbidities. The control group (n = 30) were age and gender matched. After three months on methylphenidate, the ADHD children were retested. The control group was also retested after three months. Results Before treatment, ADHD children had lower scores than the control group on the tests (p ≤ 0.001) and after methylphenidate had fewer test errors than before (p ≤ 0.001) Conclusion Methylphenidate treatment improves the working memory, inhibitory control and mental flexibility of ADHD boys.

The impact of illness variables of a sample of ADHD children on their parents

2016 ◽  
Vol 33 (S1) ◽  
pp. S343-S343
Author(s):  
M. Abdelhameed ◽  
M. Hassan ◽  
N. Abdelfadeel ◽  
M. Abdelshaheed
Keyword(s):  
Psychological Stress ◽  
Severity Of Illness ◽  
Psychological State ◽  
Control Group ◽  
Paranoid Ideation ◽  
Children With Adhd ◽  
Adhd Children ◽  
Competing Interest ◽  
Study Type ◽  
The Impact

IntroductionThe symptoms and behavior of children with ADHD impose demands and difficulties on part of their caring parents, which may cause the latter group to suffer psychological stress.ObjectivesThe study of the suffering and symptomatic expression of psychological stress in parents of children with ADHD.AimsTo study type and severity of symptoms in children with ADHD and the effect of that on the stress response of their parents.MethodsThirty-seven children with ADHD diagnosed clinically and with Conner's Test were studied using Child Behavior Chick List (CBCL). Available parents for each child were interviewed and studied with Symptom Chick List 90 Revised (SCL90R). Two control groups were used for both ADHD children and their parents.ResultsThe mean age of the children with ADHD was 7.1 ± 1.6, they were 22 males and 15 females. Parents of these children scored highly on total and subscales of SCL90R, they were significantly higher than their control group on total and some of these subscales including somatization, interpersonal, depression, paranoid ideation and hostility domains. Depression and paranoid ideation of ADHD children parents were positively and significantly correlated with most of the sub-items of Conner's test of their children. In addition, somatization, depression and hostility of parents were positively and significantly correlated with most of the sub-items of CBCL of their ADHD children.ConclusionsThe symptoms, behavior and severity of illness of children with ADHD have a great impact on their parents’ psychological state of suffering and stress.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Caries Experience Associated with Attention – Deficit / Hyperactivity Disorder

2006 ◽  
Vol 30 (1) ◽  
pp. 3-8 ◽  
Author(s):  
Michael Todd Grooms ◽  
Martha Ann Keels ◽  
Michael Roberts ◽  
F. Thomas McIver
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Caries Experience ◽  
Control Group ◽  
Daily Routine ◽  
Healthy Children ◽  
Children With Adhd ◽  
Hyperactivity Disorder ◽  
Whole Saliva ◽  
Significant Difference

The purpose of this cross-sectional study was to examine whether children with attention-deficit / hyperactivity disorder (ADHD) had a total caries experience that was equivalent to children without the disorder. Methods: The test sample included children ages 6 to 10 years old diagnosed with ADHD by physicians at Duke University Medical Center. The control group also included healthy children 6 to 10 years old without the diagnosis of ADHD.A visual dental exam for caries was performed and a sample of whole, unstimulated saliva was collected. The parent / guardian of each participant completed a health/medication history and a questionnaire concerning the child's oral health and habits, daily routine, and demographic information. Results: Wilcoxon and chi-square tests showed that children with ADHD have significantly more enamel caries in the primary and permanent dentitions and a significantly higher prevalence of total caries experience when compared to controls. There was no significant difference in whole saliva production between the ADHD children and the controls. Conclusions: Dentists should be aware that children with ADHD are at higher risk for caries.

scholarly journals Anxiety disorders in children with attention deficit/hyperactivity disorder

2020 ◽  
Vol 3 (4) ◽  
pp. 302-308
Author(s):  
E.A. Korabel’nikova ◽  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Anxiety Disorders ◽  
Attention Deficit ◽  
Control Group ◽  
Study Group ◽  
Healthy Children ◽  
Children With Adhd ◽  
Hyperactivity Disorder ◽  
Anxiety Test ◽  
Age Related

Aim: to assess the prevalence and presentations of anxiety in preschool children with attention deficit/hyperactivity disorder (ADHD). Patients and Methods: preschoolers (4–6 years) and their parents were enrolled. 30 children with ADHD and their parents were included in the study group and 15 healthy children and their parents were included in the control group. The study was performed in Moscow kindergartens. Clinical anamnestic, experimental psychological (Р. Temple, М. Dorkey, and Е.W. Amen anxiety test adapted by V.M. Astapov; “Fears in Houses” test modified by M.A. Panfilova; questionnaire for anxiety in children for a teacher and parents by G.P. Lavrent’eva and T.M. Titarenko), and statistical tests were applied. Results: in children with ADHD, a significantly higher level of anxiety was reported as demonstrated by Р. Temple, М. Dorkey, and Е.W. Amen anxiety test results (i.e., the test completed by children themselves). The percentage of children with 15 fears or more was significantly higher in the study group compared to the control group. Most preschoolers from both groups experience so-called age-related fears. In addition, age-inappropriate social fears (e.g., a fear of punishment or a fear of being late for kindergarten) were revealed in children with ADHD. These fears were much more common in the study group compared to the control group. Conclusions: our findings demonstrate a higher level of anxiety in children with ADHD compared to healthy children. Therefore, anxiety may be regarded as an ADHD-associated factor. In addition to typical age-related fears, children with ADHD experience so-called social fears. This phenomenon illustrates a fear of disapproval and punishment and a propensity for low self-esteem. KEYWORDS: attention deficit/hyperactivity disorder, anxiety disorders, preschoolers. FOR CITATION: Korabel’nikova E.A. Anxiety disorders in children with attention deficit/hyperactivity disorder. Russian Journal of Woman and Child Health. 2020;3(4):302–308. DOI: 10.32364/2618-8430-2020-3-4-302-308.

Sense of Time in Children with Attention-Deficit/Hyperactivity Disorder (ADHD)

2010 ◽  
Vol 69 (1) ◽  
pp. 7-14 ◽  
Author(s):  
Vincent Quartier ◽  
Grégoire Zimmermann ◽  
Sadegh Nashat
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Control Group ◽  
Children With Adhd ◽  
Hyperactivity Disorder ◽  
Knowledge Questionnaire ◽  
Adhd Children ◽  
French Speaking ◽  
Sense Of Time ◽  
Perception Of Time

Parents of children with attention-deficit/hyperactivity disorder (ADHD) frequently report that their children have a poor sense of time. Several studies looking at the perception of time mentioned a form of temporal myopia. The present study investigates the sense of time in children with ADHD. Twenty-two French-speaking Swiss children with ADHD and 22 controls between the ages of 6 and 13 years were tested using a conventional time knowledge questionnaire and two Piagetian time conservation tasks. Parents were asked to complete the “It’s about time” questionnaire. Better performance was observed in matched control group children than in children with ADHD on a conventional time knowledge questionnaire. For children under 10 years of age, the two Piagetian time conservation tasks were able to differentiate children with and without ADHD. Parents of ADHD children reported more frequently that their children had time-related difficulties in daily activities. This study suggests that children with ADHD take longer to develop several time-related abilities.

The Impact of Copper in Children with Attention Deficit Hyperactivity Disorder

2017 ◽  
Vol 68 (2) ◽  
pp. 279-283
Author(s):  
Mihail Silviu Tudosie ◽  
Elena Truta ◽  
Ana Maria Davitoiu ◽  
Luminita Stanciulescu ◽  
George Jinescu ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Copper Concentration ◽  
Graphite Furnace ◽  
Urine Samples ◽  
Health State ◽  
Adhd Symptoms ◽  
Children With Adhd ◽  
Hyperactivity Disorder ◽  
The Impact

During one year (september 2013 � september 2014), 50 children from the residential institution for children SOS Satele Copiilor Bucharest, where included in our research. The children were distributed in two groups: Group A which consisted of 25 children (12 girls, 13 boys) who were not diagnosed with attention deficit hyperactivity disorder (ADHD) and Group B which consisted of 25 children (14 boys, 11 girls) who were diagnosed with ADHD. Initially, the two groups were subjected at a psycho-diagnostic battery of tests, one of them being the Evaluating the Health State of children with ADHD questionnaire elaborated by us, particularly for this research, with the purpose of highlighting the direct link between the children health state and their ADHD symptoms. This study sought to determine the concentration of copper in urine samples from a group of children with ADHD and a group of normal children, to highlight the role of copper in the development of ADHD symptoms. Levels of copper concentration in urine samples from the two groups were processed by Student�s t-Test. Statistical analysis showed that the arithmetic averages of copper concentration in urine samples, of the two groups do not differ significantly, so copper may be causing ADHD symptoms occur. The copper content in urine samples has been determined using atomic absorption spectrometry with graphite furnace.

scholarly journals Diagnostic Application of Postmortem Cardiac Troponin I Pericardial Fluid/Serum Ratio in Sudden Cardiac Death

Diagnostics ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 614
Author(s):  
Diana Hernández-Romero ◽  
María del Rocío Valverde-Vázquez ◽  
Juan Pedro Hernández del Rincón ◽  
José A. Noguera-Velasco ◽  
María D. Pérez-Cárceles ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Sudden Cardiac Death ◽  
Cardiac Troponin ◽  
Cardiac Death ◽  
Troponin I ◽  
Sampling Site ◽  
Pericardial Fluid ◽  
Cardiac Troponin I ◽  
Control Group ◽  
Complementary Method

In approximately 5% of unexpected deaths, establishing a conclusive diagnosis exclusively on the basis of anatomo-pathological findings in a classic autopsy is difficult. Postmortem biomarkers have been actively investigated as complementary indicators to help to reach valid conclusions about the circumstances of death. Several studies propose either the pericardial fluid or peripheral veins as a location for troponin determination, but the optimum sampling site is still a matter of debate. Our objective was to evaluate the association between the ratio of troponin values in the pericardial fluid and serum (determined postmortem) and the diagnosis of acute myocardial infarction (AMI) in the context of sudden cardiac death. We included 175 forensic cases. Two groups were established: AMI deaths (48; 27.4%) and the control group (127; 72.6%). The cardiac Troponin I (cTnI) values in the pericardial fluid and the troponin ratio were found to be associated with the cause of death. Univariate regression analyses showed that both age and the cTnI ratio were significantly associated with the diagnosis of AMI death. In a multivariate analysis, adjusting for confounding factors, the age and cTnI ratio were independent predictors of death from myocardial infarction. We performed a receiver operating characteristic (ROC) curve for the cTnI ratio for AMI death and selected a cut-off point. Our biomarker was found to be a valuable and highly effective tool for use in the forensic field as a complementary method to facilitate diagnosis in nonconclusive autopsies.

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