scholarly journals SERS-Based Colloidal Aptasensors for Quantitative Determination of Influenza Virus

2021 ◽  
Vol 22 (4) ◽  
pp. 1842
Author(s):  
Dmitry Gribanyov ◽  
Gleb Zhdanov ◽  
Andrei Olenin ◽  
Georgii Lisichkin ◽  
Alexandra Gambaryan ◽  
...  

Development of sensitive techniques for rapid detection of viruses is on a high demand. Surface-enhanced Raman spectroscopy (SERS) is an appropriate tool for new techniques due to its high sensitivity. DNA aptamers are short structured oligonucleotides that can provide specificity for SERS biosensors. Existing SERS-based aptasensors for rapid virus detection had several disadvantages. Some of them lacked possibility of quantitative determination, while others had sophisticated and expensive implementation. In this paper, we provide a new approach that combines rapid specific detection and the possibility of quantitative determination of viruses using the example of influenza A virus.

Nanomaterials ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1394
Author(s):  
Elena Zavyalova ◽  
Oganes Ambartsumyan ◽  
Gleb Zhdanov ◽  
Dmitry Gribanyov ◽  
Vladimir Gushchin ◽  
...  

During the COVID-19 pandemic, the development of sensitive and rapid techniques for detection of viruses have become vital. Surface-enhanced Raman scattering (SERS) is an appropriate tool for new techniques due to its high sensitivity. SERS materials modified with short-structured oligonucleotides (DNA aptamers) provide specificity for SERS biosensors. Existing SERS-based aptasensors for rapid virus detection are either inapplicable for quantitative determination or have sophisticated and expensive construction and implementation. In this paper, we provide a SERS-aptasensor based on colloidal solutions which combines rapidity and specificity in quantitative determination of SARS-CoV-2 virus, discriminating it from the other respiratory viruses.


RSC Advances ◽  
2017 ◽  
Vol 7 (77) ◽  
pp. 49097-49101 ◽  
Author(s):  
J. Huang ◽  
P. Liang ◽  
J. Xu ◽  
Y. Wu ◽  
W. Shen ◽  
...  

Coumarin is harmful to health but still used in cosmetics, tobacco, or illegally added into food as a spice in trace amounts so that it is exceedingly difficult to be determined accurately.


2001 ◽  
Vol 32 (11) ◽  
pp. 971-974 ◽  
Author(s):  
A. Lorén ◽  
C. Eliasson ◽  
M. Josefson ◽  
K. V. G. K. Murty ◽  
M. Käll ◽  
...  

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