scholarly journals Long Term Findings Concerning the Mental and Physical Condition, Quality of Life and Sexuality after Laparoscopically Assisted Creation of a Neovagina (Modified Vecchietti Technique) in Young MRKHS (Mayer-Rokitansky-Küster-Hauser-Syndrome) Patients

2021 ◽  
Vol 10 (6) ◽  
pp. 1269
Author(s):  
Katharina Rall ◽  
Bernadette Schenk ◽  
Norbert Schäffeler ◽  
Dorit Schöller ◽  
Andrina Kölle ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sexual Function ◽  
Large Body ◽  
Interdisciplinary Approach ◽  
Psychosocial Adaptation ◽  
Physical And Mental Health ◽  
Vaginal Aplasia ◽  
Patient Reported ◽  
Before And After

The Mayer-Rokitansky-Küster-Hauser-syndrome (MRKHS) is characterized by a congenital uterine and vaginal aplasia. A large body of literature reports that a diagnosis of MRKHS has a variety of psychological effects on patients and doubts about female identity. The aim of the underlying study was to detect the patient-reported physical and mental health and sexual function before and after laparoscopically assisted creation of a neovagina. 160 women with MRKHS who underwent this type of surgery between September 2009 and December 2015 were invited to complete the questionnaires. Packages consisting of six questionnaires were handed out before surgery, six and 12 months after surgery. Data from 82 patients could be included in the study. Patients had a mean age of 19.9 years at inclusion in the study. We detected an impairment of the health-related mental quality of life. There was no higher risk for psychological disorders. MRKHS patients show similar self-acceptance and normal body image compared to the general population. The sexual function is limited before surgery and normalizes after surgery. Useful factors for coping with the disease are an interdisciplinary approach in diagnostics and treatment, psychosocial adaptation as well as a supportive social environment.

The Obesity Epidemic and Sexual Health (DRAFT)

2018 ◽  
Author(s):  
Steven Lamm ◽  
Jonathan Bekisz
Keyword(s):  
Quality Of Life ◽  
Sexual Function ◽  
Self Esteem ◽  
Physical And Mental Health ◽  
Complex Interplay ◽  
Obesity Epidemic ◽  
Attitudes And Behaviors ◽  
Males And Females ◽  
Meaningful Relationships

There are few conditions that have such wide-ranging effects on sexual function as obesity. Though many of the exact mechanisms are yet to be elucidated, its impacts on the cardiovascular, endocrine, and nervous systems, among others, bestow upon obesity an almost unrivaled ability to devastate the human sexual response. Further, the effects of obesity extend beyond the purely physiologic into the psychologic and have the ability to impair both males and females alike. The downstream sequelae of sexual dysfunction secondary to obesity can significantly impair an individual’s quality of life, affecting his or her self-esteem, opportunity to form and maintain meaningful relationships, and ability to reproduce if desired, all of which can further promote pro-obesogenic attitudes and behaviors. Thus there is tremendous incentive for appreciation and understanding of the complex interplay between obesity and sexual function, as well as their relation to an individual’s overall physical and mental health.

scholarly journals Patient-reported Quality of Life Before and After Total Knee Arthroplasty: A Prospective Multicentre Cohort Study

2021 ◽  
Author(s):  
Jinghui Chang ◽  
Manru Fu ◽  
Peihua Cao ◽  
Changhai Ding ◽  
Dong Wang
Keyword(s):  
Quality Of Life ◽  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
Family Income ◽  
Knee Function ◽  
Targeted Interventions ◽  
Patient Reported ◽  
Before And After ◽  
Total Knee

Abstract Background: To identify patients’ self-reported health-related quality of life (HRQoL) before and after total knee arthroplasty (TKA) and determine factors contributing to any heterogeneity in HRQoL. Methods: This prospective multicentre study included 404 patients with knee osteoarthritis who underwent TKA between 1 April and 30 December 2019 and in whom HRQoL was assessed preoperatively and at 7 days and 1, 3, and 6 months postoperatively. Sociodemographic characteristics were assessed using a general information questionnaire; disability, using the Knee Injury and Osteoarthritis Outcome Score; pain, using the visual analogue scale (VAS) score; and HRQoL, using the European Quality of Life Five Dimension Five Level (EQ-5D-5L) score. Potential heterogeneity and factors influencing longitudinal changes in HRQoL were analysed using a growth mixture model.Results: The mean EQ-5D-5L score improved from 0.69 preoperatively to 0.90 at 6 months postoperatively. Two types of longitudinal heterogeneity were identified: (1) a group of patients with a small and slow improvement in HRQoL and (2) a group of patients who showed marked and rapid improvement in HRQoL. The main characteristics of the latter group were a monthly family income >2000 yuan, exercising for approximately 30 min daily, and better knee function at baseline. Baseline knee function and change in knee function were significantly associated with the percentage change in HRQoL.Conclusions: HRQoL improved considerably after TKA. However, there was some heterogeneity in the changes in HRQoL depending on certain patient characteristics. Targeted interventions should focus on these differences to optimise the outcomes of TKA.

scholarly journals Longitudinal prospective evaluation of oral health-related quality of life in young patients undergoing fixed orthodontic appliance treatment as part of a randomised trial

2020 ◽  
Author(s):  
Mustafa Elhussein ◽  
Philip Benson
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Orthodontic Treatment ◽  
Well Being ◽  
Health Related Quality ◽  
Patient Reported ◽  
Before And After ◽  
Related Quality ◽  
Health Related

Abstract Background The objectives of this study were to investigate relationships between change in the aesthetic appearance before and after orthodontic treatment and patient-reported change in oral health-related quality of life (OHRQoL), and to assess the responsiveness of two OHRQoL measures to any changes from orthodontic treatment. Methods Two hundred and ten participants in a multicentre (two teaching hospitals and four specialist orthodontic practices), single blinded, randomised clinical trial with 2 parallel groups, were administered one of two age-specific questionnaires, either the Child Perceptions Questionnaire (CPQ11-14-ISF-16) or the Psychosocial Impact of Dental Aesthetics Questionnaire (PIDAQ), before and after orthodontic treatment. Clinical photographs were assessed by two groups of laypeople and orthodontists using the Index of Orthodontic Treatment Need Aesthetic Component (IOTN-AC). Results Two hundred and ten participants were randomised, and 197 completed the trial. Before and after OHRQoL data were successfully obtained from 110 participants. There was a mean reduction in the total CPQ11-14-ISF-16 scores of 3.9 (SD = 8.0), and a mean reduction of 34.2 (SD = 18.5) in the total PIDAQ score. CPQ11-14-ISF-16 demonstrated poor longitudinal construct validity (p = 0.155). Correlations between the change in total CPQ11-14-ISF-16 scores and change in IOTN-AC assessments were small for both orthodontists (r=-0.084; p = 0.516) and laypeople (r=-0.140; p = 0.225). There were higher associations between the improvement in the Social well-being (SWB) subdomain and improvement in IOTN-AC. Correlations between the changes in total PIDAQ scores and the IOTN-AC assessments, were higher in comparison to the correlations with CPQ11-14-ISF-16 (orthodontists; r = 0.223, laypeople; r = 0.025). There were no adverse effects. Conclusion CPQ11-14-ISF-16 and IOTN-AC measure different attributes. This demonstrated the role of SWB on children OHRQoL. Condition-specific measures (PIDAQ) are more responsive to change in self-reported OHRQoL than generic measures (CPQ11-14-ISF-16) after treatment. Trial Registration: The trial was registered at ClinicalTrials.gov NCT01925924.

Patient-Reported Quality of Life Before and After Chemoradiation for Intact Pancreas Cancer: A Prospective Registry Study

2021 ◽  
Vol 11 (1) ◽  
pp. e63-e69
Author(s):  
William G. Breen ◽  
Krishan R. Jethwa ◽  
Nathan Y. Yu ◽  
Grant M. Spears ◽  
William S. Harmsen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Pancreas Cancer ◽  
Registry Study ◽  
Patient Reported ◽  
Before And After

Toxicity in a multimodality approach of radical prostatectomy with radiation and hormonal therapy.

2016 ◽  
Vol 34 (2_suppl) ◽  
pp. 107-107
Author(s):  
Stacy Loeb ◽  
Meike Adam ◽  
Pierre Tennstedt ◽  
Wolfgang Huber ◽  
Juergen Bernard ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Radical Prostatectomy ◽  
Sexual Function ◽  
Hormonal Therapy ◽  
Urinary Continence ◽  
Urinary Function ◽  
Bootstrap Analysis ◽  
Patient Reported ◽  
The Impact

107 Background: While the optimal use and timing of secondary therapy after radical prostatectomy remain controversial, there are limited data on the patient-reported outcomes following multimodality therapy. Our objective was to assess the impact of additional radiation and/or hormonal therapy on long-term urinary continence, quality of life and potency after radical prostatectomy. Methods: Among 13150 men treated by radical prostatectomy (RP) from 1992-2013, 905 underwent secondary radiation therapy (RP+RT), 407 received androgen deprivation therapy (RP+ADT) and 688 a combination of RT and ADT (RP+RT+ADT). Urinary function, sexual function and quality of life were evaluated annually using self-administrated validated questionnaires. Urinary function was assessed by the use of the number of pads in 24h (analyzed as 0 pads, safety only, 1-2, or ≥ 3 pads). Potency was defined as ≥ 3 points out of 5 on the question whether erections were hard enough for penetration. Quality of life was assessed using a score from 0-100%.The distribution of urinary function, sexual function and quality of life were plotted as a function of time after bootstrap analysis (n = 1000) of a propensity score matched cohort. Results: Urinary function. The distribution of 0 pads and 1 safety pad between patients with a) RP and RP+RT was 72.3% vs. 67.9% and 16.7% vs. 18.6%; b) between RP and RP+HT was 64.5% vs. 55.5% and 16.1% vs. 21.9%; c) between RP and RP+RT+ADT was 67.4% vs. 54.8% and 17.7% vs. 21.8% and d) between RP+RT and RP+RT+ADT was 64.5% vs. 55.5% and 16.1% vs. 21.9%. Potency. The distribution of potency between patients with a) RP and RP+RT was 62.9% vs. 40.0%; b) between RP and RP+HT was 59.1% vs. 29.3%; c) between RP and RP+RT+ADT was 57.4% vs. 24.0% and d) between RP+RT and RP+RT+ADT was 44.2% vs. 32.1%. Quality of life. The distribution of a score of 83.3%-100% between patients with a) RP and RP+RT was 67.9% vs. 57.4%; b) between RP and RP+HT was 57.8% vs. 41.7%; c) between RP and RP+RT+ADT was 59.3% vs. 48.2% and d) between RP+RT and RP+RT+ADT was 60.0% vs. 41.2%. Conclusions: Secondary therapy after radical prostatectomy has a negative influence on urinary function, potency and quality of life.

Sexual Function and Quality of Life Before and After Penile Prosthesis Implantation Following Radial Forearm Flap Phalloplasty

Urology ◽  
2017 ◽  
Vol 104 ◽  
pp. 204-208 ◽  
Author(s):  
Ezekiel E. Young ◽  
Daniel Friedlander ◽  
Kathy Lue ◽  
Uzoma A. Anele ◽  
Jacob L. Khurgin ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sexual Function ◽  
Penile Prosthesis ◽  
Radial Forearm Flap ◽  
Prosthesis Implantation ◽  
Forearm Flap ◽  
Before And After ◽  
Radial Forearm
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