scholarly journals Treatment Outcomes of Patients with Glomus Tympanicum Tumors Presenting with Pulsatile Tinnitus

2021 ◽  
Vol 10 (11) ◽  
pp. 2348
Author(s):  
Seung-Jae Lee ◽  
Sang-Yeon Lee ◽  
Gwang-Seok An ◽  
Kyogu Lee ◽  
Byung-Yoon Choi ◽  
...  
Keyword(s):  
Treatment Outcomes ◽  
Low Frequency ◽  
Temporal Analysis ◽  
Endovascular Embolization ◽  
Preoperative Embolization ◽  
Surgical Removal ◽  
Pulsatile Tinnitus ◽  
Post Intervention ◽  
Hearing Thresholds ◽  
Glomus Tympanicum

We reviewed the clinical characteristics and treatment outcomes of patients with glomus tympanicum tumors (GTTs) presenting with pulsatile tinnitus (PT). We explored whether transcanal sound recording-spectro-temporal analysis (TSR-STA) usefully evaluated changes in PT. The medical records of 13 patients who underwent surgical removal of GTTs were reviewed retrospectively. Two patients underwent preoperative endovascular embolization. Changes in PT, pre- and postoperative audiometry data, TSR-STA results, and clinical outcomes were evaluated. PT was the chief complaint in eight patients (61.5%) and resolved immediately after surgical intervention in all. Two patients exhibited ipsilateral, pseudo-low-frequency hearing loss (PLFHL); surgical GTT removal elicited postoperative improvements in the ipsilesional low-frequency hearing thresholds. Five patients underwent TSR-STA using previously described methods. TSR-STA revealed definite rise-and-fall patterns; surgical tumor removal abated this pattern in one patient, but, for the other four, the patterns did not change greatly post-intervention. Thus, GTT-related PT can be treated successfully (via surgical GTT removal) without complications. In selected cases, preoperative embolization reduces intraoperative hemorrhage. In PT patients with PLFHL, a detailed otoendoscopic examination of the middle ear is required to rule out a GTT. TSR-STA may usefully (and objectively) assess postoperative improvements in GTT-related PT.

scholarly journals Twenty Years of Experience in Juvenile Nasopharyngeal Angiofibroma (JNA) Preoperative Endovascular Embolization: An Effective Procedure with a Low Complications Rate

2021 ◽  
Vol 10 (17) ◽  
pp. 3926
Author(s):  
Andrea Giorgianni ◽  
Stefano Molinaro ◽  
Edoardo Agosti ◽  
Alberto Vito Terrana ◽  
Francesco Alberto Vizzari ◽  
...  
Keyword(s):  
Blood Loss ◽  
Arterial Embolization ◽  
Endovascular Embolization ◽  
External Carotid Artery ◽  
Juvenile Nasopharyngeal Angiofibroma ◽  
External Carotid ◽  
Preoperative Embolization ◽  
Surgical Removal ◽  
Intraoperative Blood Loss ◽  
Nasopharyngeal Angiofibroma

Juvenile nasopharyngeal angiofibroma (JNA) is a benign tumor of the nasal cavity that predominantly affects young boys. Surgical removal remains the gold standard for the management of this disease. Preoperative intra-arterial embolization (PIAE) is useful for reductions in intraoperative blood loss and surgical complications. In our series of 79 patients who underwent preoperative embolization from 1999 to 2020, demographics, procedural aspects, surgical management and follow-up outcome were analyzed. Embolization was performed in a similar fashion for all patients, with a superselective microcatheterization of external carotid artery (ECA) feeders and an injection of polyvinyl alcohol (PVA) particles, followed, in some cases, by the deployment of coils . Procedural success was reached in 100% of cases, with no complications such as bleeding or thromboembolic occlusion, and surgical intraoperative blood loss was significantly decreased. In conclusion, PIAE is a safe and effective technique in JNA treatment, minimizing intraoperative bleeding.

scholarly journals 1181 Thoracic Outlet Syndrome - A Miss(Ed) Diagnosis-Delayed Diagnosis Of Thoracic Outlet Syndrome Is Common And Leads To Poorer Functional Outcomes

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
S Suresh ◽  
G Kaneta ◽  
A Wignakumar ◽  
S Choksy ◽  
S Sinha ◽  
...  
Keyword(s):  
Treatment Outcomes ◽  
Thoracic Outlet Syndrome ◽  
Delayed Diagnosis ◽  
Initial Presentation ◽  
Shoulder Injury ◽  
Post Intervention ◽  
Vascular Surgeon ◽  
Delivery Of Care ◽  
Retrospective Audit ◽  
Adequate Care

Abstract Thoracic outlet syndrome was first defined by Peet in 1956 as “compression of the neurovascular structures in the interscalene triangle corresponding to the possible etiology of the symptoms”.1 Diagnosis of TOCS still remains controversial due to lack of clear referral pathways and our study aims to create one to prevent adverse treatment outcomes. Method A retrospective audit in a single vascular centre over a 11-year period correlating time of onset of symptoms to delivery of care and post intervention benefits Results Total of 50 patients were analysed during the study. 30 percent of the patients analysed were noted to be referred to a vascular surgeon 3 years post the initial presentation of symptoms. 60 percent were noted to be referred between 6-2.5 years post initial presentation. Remaining 10 percent were noted to be referred in less than 6 years. It was noted that patients belonging to the group Acohort were noted to have recurrence of symptoms, albeit minor post intervention and treatment of TOCS. Whereas recurrence was noted to be nil/ reduced in the patients intervened in less than 2 years from onset of symptoms. Furthermore, the study also noted that more than 50 percent patients with neurogenic/ venous TOCS had a history of preceeding trauma/ shoulder injury and were noted to be not investigated for TOCS. Conclusions Our study lends evidence that delayed diagnosis of thoracic outlet syndrome is common and leads to poorer functional and treatment outcomes. Hence a diagnostic pathway must be proposed and implemented at primary care which caters to diagnosis of TOCS, to avoid delays in delivery of adequate care and treatment.

scholarly journals CLUSTER–STAFF search coil magnetometer calibration – comparisons with FGM

2014 ◽  
Vol 3 (2) ◽  
pp. 153-177 ◽  
Author(s):  
P. Robert ◽  
N. Cornilleau-Wehrlin ◽  
R. Piberne ◽  
Y. de Conchy ◽  
C. Lacombe ◽  
...  
Keyword(s):  
Transfer Functions ◽  
Low Frequency ◽  
Temporal Analysis ◽  
Fluxgate Magnetometer ◽  
Data Sets ◽  
Spectral Matrix ◽  
Spatio Temporal ◽  
Cross Calibration ◽  
The Waves ◽  
The Way

Abstract. The main part of the Cluster Spatio-Temporal Analysis of Field Fluctuations (STAFF) experiment consists of triaxial search coils allowing the measurements of the three magnetic components of the waves from 0.1 Hz up to 4 kHz. Two sets of data are produced, one by a module to filter and transmit the corresponding waveform up to either 10 or 180 Hz (STAFF-SC), and the second by the onboard Spectrum Analyser (STAFF-SA) to compute the elements of the spectral matrix for five components of the waves, 3 × B and 2 × E (from the EFW experiment), in the frequency range 8 Hz to 4 kHz. In order to understand the way the output signals of the search coils are calibrated, the transfer functions of the different parts of the instrument are described as well as the way to transform telemetry data into physical units across various coordinate systems from the spinning sensors to a fixed and known frame. The instrument sensitivity is discussed. Cross-calibration inside STAFF (SC and SA) is presented. Results of cross-calibration between the STAFF search coils and the Cluster Fluxgate Magnetometer (FGM) data are discussed. It is shown that these cross-calibrations lead to an agreement between both data sets at low frequency within a 2% error. By means of statistics done over 10 yr, it is shown that the functionalities and characteristics of both instruments have not changed during this period.

Treatment Outcomes of Endovascular Embolization for Pelvic Congestion Syndrome

2018 ◽  
Vol 51 ◽  
pp. 282-283
Author(s):  
William Wilson ◽  
Lyssa Ochoa ◽  
Jenny J. Lee ◽  
Mathew Cheung ◽  
Peter H. Lin
Keyword(s):  
Treatment Outcomes ◽  
Endovascular Embolization ◽  
Pelvic Congestion Syndrome ◽  
Pelvic Congestion

scholarly journals Indocyanin Green Videoangiography Study of Hemangioblastomas

2011 ◽  
Vol 38 (1) ◽  
pp. 41-47 ◽  
Author(s):  
Yasuo Murai ◽  
Koji Adachi ◽  
Fumihiro Matano ◽  
Kojiro Tateyama ◽  
Akira Teramoto
Keyword(s):  
Residual Tumor ◽  
Preoperative Embolization ◽  
Surgical Removal ◽  
Vascular Differentiation ◽  
Brain Surface ◽  
Contrast Enhanced ◽  
Preoperative Magnetic Resonance ◽  
Magnetic Resonance Imaging Mri ◽  
The Brain ◽  
Angiographic Findings

Abstract:Objective:We present herein the intraoperative indocyanin green videoangiography (ICGVAG) findings for three cases of cerebellar hemangioblastoma (HB).Cases:Cerebellar HB was detected in three patients presenting with symptoms of vertigo and/or headaches and diagnosed on the basis of preoperative magnetic resonance imaging (MRI) and cerebral angiographic findings. Preoperative embolization of the tumor feeding artery was not performed in any of the patients. None of the patients underwent any procedure prior to ICGVAG that would affect the ICG findings, such as perilesional hemostatic coagulation or ablation. In each patient, it was possible to judge the approximate location of the tumor in relation to the brain surface and to distinguish the feeding and draining vessels. Following resection of the tumor, ICGVAG images confirmed that the mural nodule had been eliminated. None of the patients required blood transfusion, either during or after the surgery. For each patient, the lesion was pathologically confirmed as HB, postoperative contrast-enhanced MRI confirmed the absence of residual tumor, and diffusion-weighted MRI revealed no ischemic changes.Results:Differentiation of feeding and draining vessels in the region of the lesion is particularly important for successful surgical removal of HB. In the present three patients, ICGVAG findings enabled easy vascular differentiation and were also useful for confirming that there was no residual tumor. Indocyanin green videoangiography was concluded to be useful for safe resection of HB.

Effects of a neoprene wetsuit hood on low‐frequency underwater hearing thresholds

1999 ◽  
Vol 105 (2) ◽  
pp. 1298-1298 ◽  
Author(s):  
John R. Sims ◽  
David M. Fothergill ◽  
Michael D. Curley
Keyword(s):  
Low Frequency ◽  
Hearing Thresholds ◽  
Underwater Hearing

scholarly journals RADIOAUTOGRAPHIC ANALYSIS OF THE SECRETORY PROCESS IN THE PAROTID ACINAR CELL OF THE RABBIT

1972 ◽  
Vol 53 (2) ◽  
pp. 290-311 ◽  
Author(s):  
J. David Castle ◽  
James D. Jamieson ◽  
George E. Palade
Keyword(s):  
Intracellular Transport ◽  
Secretory Granules ◽  
Close Association ◽  
Low Frequency ◽  
Secretory Process ◽  
Secretory Proteins ◽  
Surgical Removal ◽  
Storage Granules ◽  
And Storage

Intracellular transport of secretory proteins has been studied in the parotid to examine this process in an exocrine gland other than the pancreas and to explore a possible source of less degraded membranes than obtainable from the latter gland. Rabbit parotids were chosen on the basis of size (2–2.5 g per animal), ease of surgical removal, and amylase concentration. Sites of synthesis, rates of intracellular transport, and sites of packaging and storage of newly synthesized secretory proteins were determined radioautographically by using an in vitro system of dissected lobules capable of linear amino acid incorporation for 10 hr with satisfactory preservation of cellular fine structure. Adequate fixation of the tissue with minimal binding of unincorporated labeled amino acids was obtained by using 10% formaldehyde-0.175 M phosphate buffer (pH 7.2) as primary fixative. Pulse labeling with leucine-3H, followed by a chase incubation, showed that the label is initially located (chase: 1–6 min) over the rough endoplasmic reticulum (RER) and subsequently moves as a wave through the Golgi complex (chase: 16–36 min), condensing vacuoles (chase: 36–56 min), immature granules (chase: 56–116 min), and finally mature storage granules (chase: 116–356 min). Distinguishing features of the parotid transport apparatus are: low frequency of RER-Golgi transitional elements, close association of condensing vacuoles with the exit side of Golgi stacks, and recognizable immature secretory granules. Intracelular processing of secretory proteins is similar to that already found in the pancreas, except that the rate is slower and the storage is more prolonged.

Spatio-temporal analysis of stimuli-modulated spontaneous low frequency oscillations

2007 ◽  
Vol 52 (11) ◽  
pp. 1475-1483 ◽  
Author(s):  
Ming Li ◽  
YaDong Liu ◽  
DeWen Hu ◽  
YuCheng Wang ◽  
FaYi Liu ◽  
...  
Keyword(s):  
Low Frequency ◽  
Temporal Analysis ◽  
Low Frequency Oscillations ◽  
Spatio Temporal

scholarly journals Yoga as a Complementary Treatment of Depression: Effects of Traits and Moods on Treatment Outcome

2007 ◽  
Vol 4 (4) ◽  
pp. 493-502 ◽  
Author(s):  
David Shapiro ◽  
Ian A. Cook ◽  
Dmitry M. Davydov ◽  
Cristina Ottaviani ◽  
Andrew F. Leuchter ◽  
...  
Keyword(s):  
Treatment Outcome ◽  
Emotional Regulation ◽  
Partial Remission ◽  
Biological Effects ◽  
Low Frequency ◽  
Cost Effective ◽  
Future Research ◽  
Post Intervention ◽  
Complementary Treatment ◽  
Before And After

Preliminary findings support the potential of yoga as a complementary treatment of depressed patients who are taking anti-depressant medications but who are only in partial remission. The purpose of this article is to present further data on the intervention, focusing on individual differences in psychological, emotional and biological processes affecting treatment outcome. Twenty-seven women and 10 men were enrolled in the study, of whom 17 completed the intervention and pre- and post-intervention assessment data. The intervention consisted of 20 classes led by senior Iyengar yoga teachers, in three courses of 20 yoga classes each. All participants were diagnosed with unipolar major depression in partial remission. Psychological and biological characteristics were assessed pre- and post-intervention, and participants rated their mood states before and after each class. Significant reductions were shown for depression, anger, anxiety, neurotic symptoms and low frequency heart rate variability in the 17 completers. Eleven out of these completers achieved remission levels post-intervention. Participants who remitted differed from the non-remitters at intake on several traits and on physiological measures indicative of a greater capacity for emotional regulation. Moods improved from before to after the yoga classes. Yoga appears to be a promising intervention for depression; it is cost-effective and easy to implement. It produces many beneficial emotional, psychological and biological effects, as supported by observations in this study. The physiological methods are especially useful as they provide objective markers of the processes and effectiveness of treatment. These observations may help guide further clinical application of yoga in depression and other mental health disorders, and future research on the processes and mechanisms.

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