scholarly journals Wide-Field Swept-Source OCT Analysis of Interocular Symmetry of Choroidal Thickness in Subjects with Uncomplicated Pachychoroid

2021 ◽  
Vol 10 (18) ◽  
pp. 4253
Author(s):  
Min-Su Kim ◽  
Hyung-Bin Lim ◽  
Woo-Hyuk Lee ◽  
Yeo-Kyoung Won ◽  
Ki-Yup Nam ◽  
...  
Keyword(s):  
Choroidal Thickness ◽  
Anatomical Variation ◽  
Correlation Coefficients ◽  
Wide Field ◽  
Macular Area ◽  
Swept Source ◽  
Swept Source Oct ◽  
Peripheral Areas ◽  
Positive Correlations ◽  
The Right

Background: We aimed to study the bilateral choroidal thickness (CT) symmetry and difference in uncomplicated pachychoroid subjects using wide-field swept-source optical coherence tomography (SS-OCT). Methods: All subjects underwent a wide-field 16-mm one-line scan using SS-OCT. Bilateral CT was measured at, and compared among, the following 12 points: three points at 900-µm intervals from the nasal optic disc margin (nasal peripapillary area), one point at the subfovea, six points at 900-µm intervals from the fovea to the nasal and temporal areas (macular area), and two peripheral points 5400 and 8100 µm from the fovea (peripheral area). Results: There were no statistically significant differences in CT between the right and left eyes in any area (all p > 0.05); they all showed significant positive correlations (all p < 0.01). However, the correlation coefficients (ρ) were smaller for the nasal peripapillary and peripheral areas compared to the macular area. Conclusions: The CTs in each region were bilaterally symmetrical in subjects with uncomplicated pachychoroid. However, interocular difference in CT increased from the center to the periphery, indicating that the anatomical variation of the nasal peripapillary and peripheral choroid was greater than that of the macula.

scholarly journals Wide-field Swept-source OCT Analysis of Interocular Symmetry of Choroidal Thickness in Subjects with Uncomplicated Pachychoroid

2021 ◽  
Author(s):  
Min-Su Kim ◽  
Hyung-Bin Lim ◽  
Woo-Hyuk Lee ◽  
Yeo-Kyoung Won ◽  
Gi-Yup Nam ◽  
...  
Keyword(s):  
Choroidal Thickness ◽  
Anatomical Variation ◽  
Correlation Coefficients ◽  
Wide Field ◽  
Macular Area ◽  
Clinical Factor ◽  
Swept Source ◽  
Peripheral Area ◽  
Peripheral Areas ◽  
The Right

Abstract Purpose: To study the bilateral choroidal thickness (CT) symmetry and difference in uncomplicated pachychoroid subjects using wide-field swept-source optical coherence tomography (SS-OCT).Methods: All subjects underwent a wide-field 16-mm 1-line scan using SS-OCT. Bilateral CT was measured at, and compared among, the following 12 points: 3 points at 900-µm intervals from the nasal optic disc margin (nasal peripapillary area), 1 point at the subfovea, 6 points at 900-µm intervals from the fovea to the nasal and temporal areas (macular area), and 2 peripheral points 5,400 and 8,100 µm from the fovea (peripheral area). Associations between interocular CT differences in the various measurement areas and clinical factors were analyzed.Results: There was no statistically significant differences in CT between the right and left eyes in any area (all p > 0.05); they all showed significant positive correlations (all p < 0.01). However, the correlation coefficients (ρ) were smaller for the nasal peripapillary and peripheral areas compared to the macular area. In addition, the interocular axial length differences were significantly associated with interocular CT differences in the macular area, but not in the nasal peripapillary or peripheral area. No other clinical factor was associated with interocular CT differences in any area.Conclusions: The CTs in each region were bilaterally symmetrical in subjects with uncomplicated pachychoroid. However, interocular difference in CT increased from the center to the periphery, indicating that the anatomical variation of the nasal peripapillary and peripheral choroid was greater than that of the macula.

scholarly journals Wide field swept source OCT angiography of multifocal retinal and choroidal occlusions from embolic triamcinolone acetonide

2020 ◽  
Vol 18 ◽  
pp. 100704 ◽  
Author(s):  
Hasenin Al-khersan ◽  
Jonathan F. Russell ◽  
Yingying Shi ◽  
Jayanth Sridhar ◽  
Giovanni Gregori ◽  
...  
Keyword(s):  
Triamcinolone Acetonide ◽  
Oct Angiography ◽  
Wide Field ◽  
Swept Source ◽  
Swept Source Oct ◽  
Swept Source Oct Angiography

scholarly journals Combined 60° Wide-Field Choroidal Thickness Maps and High-Definition En Face Vasculature Visualization Using Swept-Source Megahertz OCT at 1050 nm

2015 ◽  
Vol 56 (11) ◽  
pp. 6284 ◽  
Author(s):  
Kathrin J. Mohler ◽  
Wolfgang Draxinger ◽  
Thomas Klein ◽  
Jan Philip Kolb ◽  
Wolfgang Wieser ◽  
...  
Keyword(s):  
Choroidal Thickness ◽  
Wide Field ◽  
High Definition ◽  
Swept Source ◽  
En Face

Direct comparison of spectral-domain and swept-source OCT in the measurement of choroidal thickness in normal eyes

2013 ◽  
Vol 98 (3) ◽  
pp. 334-338 ◽  
Author(s):  
Sergio Copete ◽  
Ignacio Flores-Moreno ◽  
Javier A Montero ◽  
Jay S Duker ◽  
José M Ruiz-Moreno
Keyword(s):  
Choroidal Thickness ◽  
Spectral Domain ◽  
Swept Source ◽  
Swept Source Oct

Choroidal Thickness and Structural Glaucoma Parameters in Glaucomatous, Preperimetric Glaucomatous, and Healthy Eyes using Swept-Source OCT

2017 ◽  
Vol 27 (5) ◽  
pp. 548-554 ◽  
Author(s):  
Handan Akil ◽  
Mayss Al-Sheikh ◽  
Khalil Ghasemi Falavarjani ◽  
Brian Francis ◽  
Vikas Chopra
Keyword(s):  
Nerve Fiber ◽  
Choroidal Thickness ◽  
Wide Field ◽  
Inner Plexiform Layer ◽  
Fiber Layer ◽  
Swept Source ◽  
Nerve Fiber Layer ◽  
Rnfl Thickness ◽  
The Mean ◽  
Healthy Eyes

Purpose To evaluate choroidal thickness (CT) and its relationship with retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer thickness (GCIPLT) in glaucomatous, preperimetric glaucomatous, and healthy eyes using swept-source optical coherence tomography (SS-OCT). Methods Fifty eyes with primary open-angle glaucoma, 20 eyes with preperimetric glaucoma, and 20 age-matched healthy eyes were enrolled. Three-dimensional wide-field (12 × 9 mm) images were obtained using a SS-OCT instrument. Peripapillary CT and RNFL thickness, as well as macular CT and GCIPLT, were recorded. The correlation of the CT with nerve fiber layer and GCIPLT measurements was assessed. The association between CT and potential confounding variables including age, sex, axial length, intraocular pressure, and central corneal thickness was also examined. Results Mean peripapillary CTs were 111.7 ± 41.7, 127.7 ± 40.1, and 120.8 ± 35.4 μm in glaucomatous, preperimetric glaucomatous, and normal eyes, respectively. There was statistically significant but weak correlation for the mean RNFL and mean peripapillary CT in glaucomatous subjects (r = 0.341, p = 0.04). There was a significant correlation between RNFL thickness and peripapillary CT in 1, 2, 5, and 6 clock hours of glaucomatous eyes (r = 0.410, p = 0.005; r = 0.316, p = 0.03; r = 0.346, p = 0.02; r = 0.35, p = 0.04, respectively). Mean macular CT was 181.5 ± 70.5, 187.4 ± 65.5, and 185.4 ± 76.4 μm in glaucomatous, preperimetric glaucomatous, and healthy eyes, respectively (p = 0.7). There was no statistically significant correlation between the mean GCIPLT and mean macular CT in all subjects (p>0.05). Conclusions Choroidal thinning and its correlation with other parameters in patients with glaucoma should be further investigated with the proprietary software of SS-OCT.

scholarly journals Evaluation of Choroidal Thickness Using Optical Coherent Tomography: A Review

2021 ◽  
Vol 8 ◽  
Author(s):  
Rui Xie ◽  
Bingjie Qiu ◽  
Jay Chhablani ◽  
Xinyuan Zhang
Keyword(s):  
Optical Coherence Tomography ◽  
Choroidal Thickness ◽  
Enhanced Depth Imaging ◽  
Swept Source ◽  
Depth Imaging ◽  
Spectral Domain Oct ◽  
Tremendous Progress ◽  
Measurement Methodology ◽  
Swept Source Oct ◽  
Spectrum Disorders

The choroid is the main source of blood and nourishment supply to the eye. The dysfunction of the choroid has been implicated in various retinal and choroidal diseases. The identification and in-depth understanding of pachychoroid spectrum disorders are based on the tremendous progress of optical coherence tomography (OCT) technology in recent years, although visibility of choroid is challenging in the era of the time or spectral domain OCT. The recent rapid revolution of OCTs, such as the enhanced depth imaging OCT and the swept-source OCT, has greatly contributed to the significant improvement in the analysis of the morphology and physiology of the choroid precisely, especially to the choroid–scleral boundary and vasculature. The present review highlights the recently available evidence on the measurement methodology and the clinical significance of choroidal thickness in retinal or choroidal disorders.

scholarly journals Choroidal Thickness Profile in Chorioretinal Diseases: Beyond the Macula

2021 ◽  
Vol 8 ◽  
Author(s):  
Young Ho Kim ◽  
Jaeryung Oh
Keyword(s):  
Clinical Studies ◽  
Choroidal Thickness ◽  
Posterior Part ◽  
Enhanced Depth Imaging ◽  
Diagnostic Tools ◽  
Swept Source ◽  
Clinical Method ◽  
Reliable Parameter ◽  
Swept Source Oct ◽  
Ct Measurement

Enhanced depth imaging optical coherence tomography (EDI-OCT) and swept-source OCT (SS-OCT) have emerged as essential diagnostic tools in the study and management of various chorioretinal diseases. Evidence from early clinical studies using EDI-OCT and SS-OCT indicates that choroidal dysfunction plays a major role in the pathogenesis of chorioretinal diseases. Measurement of choroidal thickness (CT) has already become a major research and clinical method, and CT is considered as an indicator of choroidal status in a variety of ophthalmic diseases. Recently, CT measurement has also been proposed as a non-invasive marker for the early detection and monitoring of various systemic diseases. Among the several possible CT measurement locations, subfoveal CT has rapidly become a reliable parameter for measuring CT in healthy and diseased eyes. Moreover, recent advancements in OCT technology have enabled faster and wider imaging of the posterior part of the eye, allowing the various changes in CT as measured outside the macula to be shown accordingly. In this review, we first provide an overview of the results of clinical studies that have analyzed the healthy macular choroid and that in various chorioretinal diseases, and then summarize the current understanding of the choroid outside the macula. We also examine the CT profile as an index that encompasses both within and outside of the macula. Furthermore, we describe the clinical applications of ultrawide OCT, which enables visualization of the far periphery, and discuss the prospects for the development of more reliable choroidal parameters that can better reflect the choroid's characteristics.

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