scholarly journals Sinonasal-Related Orbital Infections in Children: A Clinical and Therapeutic Overview

2019 ◽  
Vol 8 (1) ◽  
pp. 101 ◽  
Author(s):  
Sara Torretta ◽  
Claudio Guastella ◽  
Paola Marchisio ◽  
Tal Marom ◽  
Samantha Bosis ◽  
...  

Sinonasal-related orbital infections (SROIs) are typically pediatric diseases that occur in 3–4% of children with acute rhinosinusitis. They are characterised by various clinical manifestations, such as peri-orbital and orbital cellulitis or orbital and sub-periosteal abscesses that may develop anteriorly or posteriorly to the orbital septum. Posterior septal complications are particularly dangerous, as they may lead to visual loss and life-threatening events, such as an intracranial abscess and cavernous sinus thrombosis. Given the possible risk of permanent visual loss due to optic neuritis or orbital nerve ischemia, SROIs are considered ophthalmic emergencies that need to be promptly recognised and treated in an urgent-care setting. The key to obtaining better clinical outcomes in children with SROIs is a multi-disciplinary assessment by pediatricians, otolaryngologists, ophthalmologists, radiologists, and in selected cases, neurosurgeons, neurologists, and infectious disease specialists. The aim of this paper is to provide an overview of the pathogenesis, clinical manifestations, diagnosis, and treatment of pediatric SROIs, and to make some practical recommendations for attending clinicians.

2018 ◽  
Vol Volume 7 ◽  
pp. 93-104 ◽  
Author(s):  
David Wright ◽  
Richard Adams ◽  
Jeanette Blacklock ◽  
Sarah Corlett ◽  
Rebecca Harmston ◽  
...  

1999 ◽  
Vol 12 (S1) ◽  
pp. 148-151 ◽  
Author(s):  
Christopher W. T. Mattern ◽  
Bradley J. Erickson ◽  
Bernard F. King ◽  
Trice W. Okryznski

Author(s):  
Suchitra Rao ◽  
Angela Moss ◽  
Molly M Lamb ◽  
Edwin J Asturias

Abstract A test-negative case-control analysis of 1478 children aged 6 months to 8 years of age seeking care at an emergency/urgent care setting with influenza like illness during the 2016-17 and 2018-19 (H3N2 predominant) influenza seasons demonstrated that influenza vaccine effectiveness did not vary significantly by the prior seasons’ vaccination status. Clinical Trials Registration NCT02979626.


2015 ◽  
Vol 9 (1) ◽  
pp. 55-57
Author(s):  
Helen Williams ◽  
Agnes Kasprowicz ◽  
Murray Ellender ◽  
Mark Ashworth

2017 ◽  
Vol 4 (2) ◽  
pp. 585
Author(s):  
Syed Md Azad ◽  
Anwesha Mukherjee ◽  
Rohit Kapoor ◽  
Rohit Bannerji ◽  
Jaydeb Ray

Patients with beta- thalassaemia major have a wide spectrum of clinical manifestations, from transfusion dependency to asymptomatic anaemia. Some may just have incidental finding of anaemia with splenomegaly during physical examination. Most of them require regular blood transfusion and their haemoglobin is maintained at an acceptable level. However they are at risk for multiple complications such as thrombo-embolic events which may be life threatening. We report here a case of beta- thalassaemia major complicated by cerebral sinus thrombosis, who had minimal clinical symptoms and signs at presentation. This case reiterates the importance of increased vigilance in the clinical management of this vulnerable group of patients. 


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