scholarly journals A Clinical Case of COVID-19-Associated Pulmonary Aspergillosis (CAPA), Illustrating the Challenges in Diagnosis (Despite Overwhelming Mycological Evidence)

2022 ◽  
Vol 8 (1) ◽  
pp. 81
Author(s):  
P. Lewis White ◽  
Jan Springer ◽  
Matt P. Wise ◽  
Hermann Einsele ◽  
Claudia Löffler ◽  
...  

The COVID-19 pandemic has resulted in large numbers of patients requiring critical care management. With the established association between severe respiratory virus infection and invasive pulmonary aspergillosis (7.6% for COVID-19-associated pulmonary aspergillosis (CAPA)), the pandemic places a significant number of patients at potential risk from secondary invasive fungal disease. We described a case of CAPA with substantial supporting mycological evidence, highlighting the need to employ strategic diagnostic algorithms and weighted definitions to improve the accuracy in diagnosing CAPA.

2022 ◽  
Vol 8 (1) ◽  
pp. 58
Author(s):  
Kerri Basile ◽  
Catriona Halliday ◽  
Jen Kok ◽  
Sharon C-A. Chen

Invasive fungal disease (IFD) associated with Coronavirus Disease 2019 (COVID-19) has focussed predominantly on invasive pulmonary aspergillosis. However, increasingly emergent are non-Aspergillus fungal infections including candidiasis, mucormycosis, pneumocystosis, cryptococcosis, and endemic mycoses. These infections are associated with poor outcomes, and their management is challenged by delayed diagnosis due to similarities of presentation to aspergillosis or to non-specific features in already critically ill patients. There has been a variability in the incidence of different IFDs often related to heterogeneity in patient populations, diagnostic protocols, and definitions used to classify IFD. Here, we summarise and address knowledge gaps related to the epidemiology, risks, diagnosis, and management of COVID-19-associated fungal infections other than aspergillosis.


2020 ◽  
Vol 12 (1) ◽  
pp. 96-103
Author(s):  
Yu. E. Melekhina ◽  
O. V. Shadrivova ◽  
E. V. Frolova ◽  
Yu. V. Borzova ◽  
E. V. Shagdileeva ◽  
...  

During  last  years  the  frequency  of  invasive  pulmonary aspergillosis  (IPA)  in  immunocompetent  patients  has  increased. Clinical case report of successful treatment invasive aspergillosis  with  influenza  A(H1N1)  presented  in  the  article. We analyzed the special literature of patients with IPA following influenza infection. The timely identification and treatment of these patients are necessary.


2018 ◽  
Vol 23 (1(part 1)) ◽  
pp. 27-37 ◽  
Author(s):  
K. Yu. Gashynova ◽  
N. S. Kolisnyk ◽  
V. V. Dmytrychenko ◽  
P. Yu. Kaplan ◽  
I. V. Kuzhevskiy ◽  
...  

1986 ◽  
Vol 2 (4) ◽  
pp. 759-773 ◽  
Author(s):  
Terry P. Clemmer ◽  
Walter R. Fairfax

2019 ◽  
Author(s):  
J Schwenck ◽  
N Beziere ◽  
A Maurer ◽  
AM Wild ◽  
H Henneberg ◽  
...  

2020 ◽  
pp. 61-63
Author(s):  
S. Sh. Kakvaeva ◽  
M. A. Magomedova ◽  
A. N. Dzhalilova

One of the most serious problems of modern medicine is sepsis. The number of patients undergoing this complication is 20–30 million (WHO) annually and has no tendency to decrease. Sepsis is characterized by severe multiple organ failure due to a violation of the response of the macroorganism to an infectious agent. Moreover, it is dangerous with high mortality. Sepsis often develops in patients with immunodeficiency conditions, which primarily include pregnant women. The article presents a clinical observation of a case of periostitis in a pregnant woman complicated by a septic state.


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