scholarly journals Effect of COVID-19-Related Lockdown οn Hospital Admissions for Asthma and COPD Exacerbations: Associations with Air Pollution and Patient Characteristics

2021 ◽  
Vol 11 (9) ◽  
pp. 867
Author(s):  
Ioanna Sigala ◽  
Timoleon Giannakas ◽  
Vassilis G. Giannakoulis ◽  
Efthimios Zervas ◽  
Aikaterini Brinia ◽  
...  
Keyword(s):  
Air Pollution ◽  
Particulate Matter ◽  
Air Pollutants ◽  
Hospital Admissions ◽  
Nitrogen Monoxide ◽  
Patient Characteristics ◽  
Chronic Obstructive ◽  
Blood Eosinophil ◽  
Obstructive Pulmonary Disease ◽  
Copd Exacerbations

We conducted a retrospective observational study to assess the hospitalization rates for acute exacerbations of asthma and COPD (chronic obstructive pulmonary disease) during the first imposed lockdown in Athens, Greece. Patient characteristics and the concentration of eight air pollutants [namely, NO (nitrogen monoxide), NO2 (nitrogen dioxide), CO (carbon monoxide), PM2.5 (particulate matter 2.5), PM10 (particulate matter 10), O3 (ozone), SO2 (sulfur dioxide) and benzene] were considered. A total of 153 consecutive hospital admissions were studied. Reduced admissions occurred in the Lockdown period compared to the Pre-lockdown 2020 (p < 0.001) or the Control 2019 (p = 0.007) period. Furthermore, the concentration of 6/8 air pollutants positively correlated with weekly hospital admissions in 2020 and significantly decreased during the lockdown. Finally, admitted patients for asthma exacerbation during the lockdown were younger (p = 0.046) and less frequently presented respiratory failure (p = 0.038), whereas patients with COPD presented higher blood eosinophil percentage (p = 0.017) and count (p = 0.012). Overall, admissions for asthma and COPD exacerbations decreased during the lockdown. This might be partially explained by reduction of air pollution during this period while medical care avoidance behavior, especially among elderly patients cannot be excluded. Our findings aid in understanding the untold impact of the pandemic on diseases beyond COVID-19, focusing on patients with obstructive diseases.

scholarly journals Effect of COVID-19-related Lockdown οn Hospital Admissions for Asthma and COPD Exacerbations: Associations with Air Pollution and Patient Characteristics

2021 ◽  
Author(s):  
Ioanna Sigala ◽  
Timoleon Giannakas ◽  
Vasileios Giannakoulis ◽  
Efthimios Zervas ◽  
Aikaterini Mprinia ◽  
...  
Keyword(s):  
Air Pollution ◽  
Respiratory Failure ◽  
Air Pollutants ◽  
Asthma Exacerbation ◽  
Hospital Admissions ◽  
Patient Characteristics ◽  
Blood Eosinophil ◽  
Copd Exacerbations ◽  
Hospitalization Rates ◽  
Acute Exacerbations

We conducted a retrospective observational study to assess the hospitalization rates for acute exacerbations of asthma and/or COPD during the first imposed lockdown in Athens, Greece. Patient characteristics and the concentration of eight air pollutants (namely, CO, NO, NO2, O3 PM2.5, PM10, SO2 and benzene) were considered. A total of 153 consecutive hospital admissions were studied. Reduced admissions occurred in the lockdown period when compared to the Pre-lockdown 2020 (p&amp;lt;0.001) or the Control 2019 (p=0.007) period. Furthermore, the concentration of 6/8 air pollutants positively correlated with weekly hospital admissions in 2020 and significantly decreased during the lockdown. Finally, admitted patients for asthma exacerbation during the lockdown were younger (p=0.046) and less frequently presented respiratory failure (p=0.038), whereas patients with COPD presented higher blood eosinophil percentage (p=0.017) and count (p=0.012). Overall, admissions for asthma and COPD exacerbations decreased during the lockdown. This might partially explained by reduction of air pollution during this period while medical care avoidance behavior, especially among elderly patients cannot be excluded. Our findings aid in understanding the untold impact of the pandemic on diseases beyond COVID-19, focusing on patients with obstructive diseases..

scholarly journals Impact of Air Pollution and Outdoor Temperature on the Rate of Chronic Obstructive Pulmonary Disease Exacerbations

Folia Medica ◽  
2017 ◽  
Vol 59 (4) ◽  
pp. 423-429 ◽  
Author(s):  
Iliya I. Krachunov ◽  
Nikolay H. Kyuchukov ◽  
Zlatina I. Ivanova ◽  
Nikolay A. Yanev ◽  
Petkana A. Hristova ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Air Pollution ◽  
Pulmonary Disease ◽  
Air Pollutants ◽  
Chronic Obstructive ◽  
Outdoor Temperature ◽  
Obstructive Pulmonary Disease ◽  
Daily Number ◽  
Copd Exacerbations ◽  
The Mean

AbstractBackground: Environmental pollution can be one of the main risk factors for acute exacerbations of chronic obstructive pulmonary disease (COPD). Aim: To study the relationship between air pollution, outdoor temperature and exacerbations of COPD. Materials and methods: COPD patients (n=1432) were followed up for one year. The levels of particulate matter up to 10 μm (PM10), nitrogen dioxide (NO2), sulfur dioxide (SO2) and outside temperatures were collected from the Environmental Agency database. Results: A total of 309 acute COPD exacerbations (AECOPD) were recorded in the analysis. The daily mean concentrations of PM10were found to correlate significantly with the daily mean concentrations of NO2and SO2(ρ 0.34 and ρ 0.49, respectively; p=0.0001). The negative correlations between the daily mean temperature and the daily mean levels of PM10, NO2and SO2were also significant (ρ -0.44, ρ -0.11, and ρ -0.37, respectively; p=0.0001). The daily number of AECOPD correlated with the mean levels of PM10in the previous six days (ρ 0.14; p=0.02) and the lower outdoor temperature (ρ -0.2; p=0.001). The negative correlation between the daily number of AECOPD and the mean daily temperature was stronger in days with levels of PM10above 50 μg/m3(ρ -0.3 p=0.02 vs. ρ -0.18 p= 0.01). Conclusion: Lower daily mean temperatures were associated with the levels of air pollutants. The level of PM10correlated with the levels of the other air pollutants. The daily number of AECOPD was found to correlate weakly, but signifi cantly with the mean level of PM10in the previous six days.

scholarly journals The impact of air pollution with the particulate matter on the development of cardiovascular diseases (literature review)

2021 ◽  
Vol 100 (6) ◽  
pp. 555-559
Author(s):  
Serafima V. German ◽  
Igor P. Bobrovnitskii ◽  
Alisa V. Balakaeva
Keyword(s):  
Air Pollution ◽  
Particulate Matter ◽  
Cardiovascular Diseases ◽  
Air Pollutants ◽  
Ultrafine Particles ◽  
The Elderly ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Short Term Exposure ◽  
The Impact

Air pollution constitutes a severe threat to human health. It is recognized as an essential risk factor for morbidity and mortality, contributing primarily to the development of cardiovascular pathology - arterial hypertension, acute myocardial infarction, heart failure, stroke. A decrease in air pollution is accompanied by reducing the incidence of cardiovascular diseases (CVD). Researches on CVD mechanisms development under the influence of air pollutants keep on being conducted. The main biological pathways are inflammation and oxidative stress, causing cascades of synergistic pathophysiological reactions. The most significant harm is caused by the particulate matter (PM) and ultrafine particles PM0.1 (less than 0.1 microns) with the highest penetrating ability. Air pollution by PM can have adverse effects with both prolonged and short-term exposure. The elderly patients with CVD, chronic obstructive pulmonary disease, diabetes mellitus, obesity are more vulnerable to exposure to pollutants. The purpose of this work is to generalize data on the issue of the interconnection of air pollution with particulate matter and cardiovascular diseases obtained over the past decade and a half. A literature search was conducted in MedLine, PubMed, Web of Science, Scopus, Google Scholar databases. The results of studies on exposure to air pollutants may vary due to differences in concentration, the composition of pollutants, duration of exposure, study design, characteristics of study participants, etc. In addition, susceptibility to air pollution can vary under the influence of other factors - economic, environmental, social, etc. The nature of atmospheric air pollution has been studied in many industrial centres of Russia. Still, only a few studies have been devoted to its effect on the country’s cardiovascular system. Awareness of this problem remains insufficient to date.

scholarly journals Winter Is Coming: A Socio-Environmental Monitoring and Spatiotemporal Modelling Approach for Better Understanding a Respiratory Disease

2018 ◽  
Vol 7 (11) ◽  
pp. 432 ◽  
Author(s):  
Lukas Marek ◽  
Malcolm Campbell ◽  
Michael Epton ◽  
Simon Kingham ◽  
Malina Storer
Keyword(s):  
Air Pollution ◽  
Census Data ◽  
Hospital Admissions ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Disease Patterns ◽  
Copd Patients ◽  
Composition Factors ◽  
Individual Composition ◽  
Modelling Approach

Chronic Obstructive Pulmonary Disease is a progressive lung disease affecting the respiratory function of every sixth New Zealander and over 300 million people worldwide. In this paper, we explored how the combination of social, demographical and environmental conditions (represented by increased winter air pollution) affected hospital admissions due to COPD in an urban area of Christchurch (NZ). We juxtaposed the hospitalisation data with dynamic air pollution data and census data to investigate the spatiotemporal patterns of hospital admissions. Spatial analysis identified high-risk health hot spots both overall and season specific, exhibiting higher rates in winter months not solely due to air pollution, but rather as a result of its combination with other factors that initiate deterioration of breathing, increasing impairments and lead to the hospitalisation of COPD patients. From this we found that socioeconomic deprivation and air pollution, followed by the age and ethnicity structure contribute the most to the increased winter hospital admissions. This research shows the continued importance of including both individual (composition) and area level (composition) factors when examining and analysing disease patterns.

Sign in / Sign up

Export Citation Format

Share Document