scholarly journals Preparation of Multifunctional Fe@Au Core-Shell Nanoparticles with Surface Grafting as a Potential Treatment for Magnetic Hyperthermia

Materials ◽  
2014 ◽  
Vol 7 (2) ◽  
pp. 653-661 ◽  
Author(s):  
Ren-Jei Chung ◽  
Hui-Ting Shih
2021 ◽  
Vol 4 (2) ◽  
pp. 2190-2210
Author(s):  
Marcus Vinícius-Araújo ◽  
Navadeep Shrivastava ◽  
Ailton A. Sousa-Junior ◽  
Sebastiao A. Mendanha ◽  
Ricardo Costa De Santana ◽  
...  

2016 ◽  
Vol 397 ◽  
pp. 20-27 ◽  
Author(s):  
M.E.F. Brollo ◽  
J.M. Orozco-Henao ◽  
R. López-Ruiz ◽  
D. Muraca ◽  
C.S.B. Dias ◽  
...  

2020 ◽  
Vol 32 (6) ◽  
pp. 065703
Author(s):  
Fernando Fabris ◽  
Javier Lohr ◽  
Enio Lima ◽  
Adriele Aparecida de Almeida ◽  
Horacio E Troiani ◽  
...  

Nanoscale ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 3164-3172 ◽  
Author(s):  
Fernando Fabris ◽  
Enio Lima ◽  
Emilio De Biasi ◽  
Horacio E. Troiani ◽  
Marcelo Vásquez Mansilla ◽  
...  

The dominant magnetic relaxation mechanism can be controlled by changing the effective magnetic anisotropy in core/shell nanoparticles, preserving its magnetic saturation, size and morphology for hyperthermia experiments.


2021 ◽  
Vol 11 (14) ◽  
pp. 6637
Author(s):  
Mohamed F. Sanad ◽  
Bianca P. Meneses-Brassea ◽  
Dawn S. Blazer ◽  
Shirin Pourmiri ◽  
George C. Hadjipanayis ◽  
...  

Today, magnetic hyperthermia constitutes a complementary way to cancer treatment. This article reports a promising aspect of magnetic hyperthermia addressing superparamagnetic and highly Fe/Au core-shell nanoparticles. Those nanoparticles were prepared using a wet chemical approach at room temperature. We found that the as-synthesized core shells assembled with spherical morphology, including face-centered-cubic Fe cores coated and Au shells. The high-resolution transmission microscope images (HRTEM) revealed the formation of Fe/Au core/shell nanoparticles. The magnetic properties of the samples showed hysteresis loops with coercivity (HC) close to zero, revealing superparamagnetic-like behavior at room temperature. The saturation magnetization (MS) has the value of 165 emu/g for the as-synthesized sample with a Fe:Au ratio of 2:1. We also studied the feasibility of those core-shell particles for magnetic hyperthermia using different frequencies and different applied alternating magnetic fields. The Fe/Au core-shell nanoparticles achieved a specific absorption rate of 50 W/g under applied alternating magnetic field with amplitude 400 Oe and 304 kHz frequency. Based on our findings, the samples can be used as a promising candidate for magnetic hyperthermia for cancer therapy.


Nanomaterials ◽  
2022 ◽  
Vol 12 (2) ◽  
pp. 262
Author(s):  
Venkatesha Narayanaswamy ◽  
Imaddin A. Al-Omari ◽  
Aleksandr S. Kamzin ◽  
Bashar Issa ◽  
Ihab M. Obaidat

Magnetically hard–soft core-shell ferrite nanoparticles are synthesized using an organometallic decomposition method through seed-mediated growth. Two sets of core-shell nanoparticles (S1 and S2) with different shell (Fe3O4) thicknesses and similar core (CoFe2O4) sizes are obtained by varying the initial quantities of seed nanoparticles of size 6.0 ± 1.0 nm. The nanoparticles synthesized have average sizes of 9.5 ± 1.1 (S1) and 12.2 ± 1.7 (S2) nm with corresponding shell thicknesses of 3.5 and 6.1 nm. Magnetic properties are investigated under field-cooled and zero-field-cooled conditions at several temperatures and field cooling values. Magnetic heating efficiency for magnetic hyperthermia applications is investigated by measuring the specific absorption rate (SAR) in alternating magnetic fields at several field strengths and frequencies. The exchange bias is found to have a nonmonotonic and oscillatory relationship with temperature at all fields. SAR values of both core-shell samples are found to be considerably larger than that of the single-phase bare core particles. The effective anisotropy and SAR values are found to be larger in S2 than those in S1. However, the saturation magnetization displays the opposite behavior. These results are attributed to the occurrence of spin-glass regions at the core-shell interface of different amounts in the two samples. The novel outcome is that the interfacial exchange anisotropy of core-shell nanoparticles can be tailored to produce large effective magnetic anisotropy and thus large SAR values.


Nanomaterials ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 149
Author(s):  
Marie-Charlotte Horny ◽  
Jean Gamby ◽  
Vincent Dupuis ◽  
Jean-Michel Siaugue

Magnetic hyperthermia on core-shell nanoparticles bears promising achievements, especially in biomedical applications. Here, thanks to magnetic hyperthermia, γ-Fe2O3 cores are able to release a DNA target mimicking the liver specific oncotarget miRNA-122. Our silica coated magnetic nanoparticles not only allow the grafting at their surface of a significant number of oligonucleotides but are also shown to be as efficient, by local heating, as 95 °C global heating when submitted to an alternative magnetic field, while keeping the solution at 28 °C, crucial for biological media and energy efficiency. Moreover, a slight modification of the silica coating process revealed an increased heating power, well adapted for the release of small oligonucleotides such as microRNA.


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