scholarly journals Study of Dynamics of a COVID-19 Model for Saudi Arabia with Vaccination Rate, Saturated Treatment Function and Saturated Incidence Rate

Mathematics ◽  
2021 ◽  
Vol 9 (23) ◽  
pp. 3134
Author(s):  
Rubayyi T. Alqahtani ◽  
Abdelhamid Ajbar

This paper proposes, validates and analyzes the dynamics of the susceptible exposed infectious recovered (SEIR) model for the propagation of COVID-19 in Saudi Arabia, which recorded the largest number of cases in the Arab world. The model incorporates a saturated incidence rate, a constant vaccination rate and a nonlinear treatment function. The rate of treatment is assumed to be proportional to the number of infected persons when this number is low and reaches a fixed value for large number of infected individuals. The expression of the basic reproduction number is derived, and the model basic stability properties are studied. We show that when the basic reproduction number is less than one the model can predict both a Hopf and backward bifurcations. Simulations are also provided to fit the model to COVID-19 data in Saudi Arabia and to study the effects of the parameters of the treatment function and vaccination rate on disease control.

2021 ◽  
Vol 2021 ◽  
pp. 1-22
Author(s):  
Rui Hu ◽  
Qingwu Gao ◽  
Bairong Wang

The mobile networks have increasingly facilitated our daily life but are also breeding grounds for malicious worms, which are considered as the main threat to cyber security. The purpose of this paper is to analyze the dynamics of worm propagation and to control the worm epidemic based on mobile-phone networks. Accordingly, we establish an SEIQR-type model to explore the worm epidemic with saturated incidence rate. This paper shows that if the basic reproduction number is less than 1, the worm-free equilibrium is asymptotically stable, and the epidemic of worm will eventually disappear and remain under control; in addition, if the basic reproduction number is greater than 1, the asymptotical stability of worm-existence equilibrium is derived to imply that the epidemic will remain persistent and uncontrollable. Our results give new insights to mobile network security, namely, that is predicting the worm spreading tendency, identifying the epidemic control strategies, and estimating the worm popularity level. Numerical experiments are conducted to show the rationality of our obtained results and the effectiveness of the control strategies.


2016 ◽  
Vol 09 (05) ◽  
pp. 1650068 ◽  
Author(s):  
Muhammad Altaf Khan ◽  
Yasir Khan ◽  
Sehra Khan ◽  
Saeed Islam

This study considers SEIVR epidemic model with generalized nonlinear saturated incidence rate in the host population horizontally to estimate local and global equilibriums. By using the Routh–Hurwitz criteria, it is shown that if the basic reproduction number [Formula: see text], the disease-free equilibrium is locally asymptotically stable. When the basic reproduction number exceeds the unity, then the endemic equilibrium exists and is stable locally asymptotically. The system is globally asymptotically stable about the disease-free equilibrium if [Formula: see text]. The geometric approach is used to present the global stability of the endemic equilibrium. For [Formula: see text], the endemic equilibrium is stable globally asymptotically. Finally, the numerical results are presented to justify the mathematical results.


2010 ◽  
Vol 15 (3) ◽  
pp. 299-306 ◽  
Author(s):  
A. Kaddar

We formulate a delayed SIR epidemic model by introducing a latent period into susceptible, and infectious individuals in incidence rate. This new reformulation provides a reasonable role of incubation period on the dynamics of SIR epidemic model. We show that if the basic reproduction number, denoted, R0, is less than unity, the diseasefree equilibrium is locally asymptotically stable. Moreover, we prove that if R0 > 1, the endemic equilibrium is locally asymptotically stable. In the end some numerical simulations are given to compare our model with existing model.


2021 ◽  
Vol 3 (2) ◽  
pp. 101-113
Author(s):  
Amit Kumar Chakraborty ◽  
M. A. Haque ◽  
M. A. Islam

Dengue is one of the major health problems in Bangladesh and many people are died in recent years due to the severity of this disease. Therefore, in this paper, a SIRS model for the human and SI model for vector population with saturated incidence rate and constant treatment function has been presented to describe the transmission of dengue. The equilibrium points and the basic reproduction number have been computed. The conditions which lead the disease free equilibrium and the endemic equilibrium have been determined. The local stability for the equilibrium points has been established based on the eigenvalues of the Jacobian matrix and the global stability has been analyzed by using the Lyapunov function theory. It is found that the stability of equilibrium points can be controlled by the reproduction number. In order to calculate the infection rate, data for infected human populations have been collected from several health institutions of Bangladesh. Numerical simulations of various compartments have been generated using MATLAB to investigate the influence of the key parameters for the transmission of the disease and to support the analytical results. The effect of treatment function over the infected compartment has been illustrated. The sensitivity of the reproduction number concerning the parameters of the model has been analyzed. Finally, the most sensitive parameter that has the highest effect over reproduction number has been identified.


2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Dipo Aldila ◽  
Brenda M. Samiadji ◽  
Gracia M. Simorangkir ◽  
Sarbaz H. A. Khosnaw ◽  
Muhammad Shahzad

Abstract Objective Several essential factors have played a crucial role in the spreading mechanism of COVID-19 (Coronavirus disease 2019) in the human population. These factors include undetected cases, asymptomatic cases, and several non-pharmaceutical interventions. Because of the rapid spread of COVID-19 worldwide, understanding the significance of these factors is crucial in determining whether COVID-19 will be eradicated or persist in the population. Hence, in this study, we establish a new mathematical model to predict the spread of COVID-19 considering mentioned factors. Results Infection detection and vaccination have the potential to eradicate COVID-19 from Jakarta. From the sensitivity analysis, we find that rapid testing is crucial in reducing the basic reproduction number when COVID-19 is endemic in the population rather than contact trace. Furthermore, our results indicate that a vaccination strategy has the potential to relax social distancing rules, while maintaining the basic reproduction number at the minimum possible, and also eradicate COVID-19 from the population with a higher vaccination rate. In conclusion, our model proposed a mathematical model that can be used by Jakarta’s government to relax social distancing policy by relying on future COVID-19 vaccine potential.


Author(s):  
C. Gokila ◽  
M. Sambath

This paper deals with stochastic Chikungunya (CHIKV) virus model along with saturated incidence rate. We show that there exists a unique global positive solution and also we obtain the conditions for the disease to be extinct. We also discuss about the existence of a unique ergodic stationary distribution of the model, through a suitable Lyapunov function. The stationary distribution validates the occurrence of disease; through that, we find the threshold value for prevail and disappear of disease within host. With the help of numerical simulations, we validate the stochastic reproduction number [Formula: see text] as stated in our theoretical findings.


2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Yu Ji ◽  
Muxuan Zheng

The basic viral infection models, proposed by Nowak et al. and Perelson et al., respectively, have been widely used to describe viral infection such as HBV and HIV infection. However, the basic reproduction numbers of the two models are proportional to the number of total cells of the host's organ prior to the infection, which seems not to be reasonable. In this paper, we formulate an amended model with a general standard incidence rate. The basic reproduction number of the amended model is independent of total cells of the host’s organ. When the basic reproduction numberR0<1, the infection-free equilibrium is globally asymptotically stable and the virus is cleared. Moreover, ifR0>1, then the endemic equilibrium is globally asymptotically stable and the virus persists in the host.


2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Jinhong Zhang ◽  
Jianwen Jia ◽  
Xinyu Song

The dynamics of SEIR epidemic model with saturated incidence rate and saturated treatment function are explored in this paper. The basic reproduction number that determines disease extinction and disease survival is given. The existing threshold conditions of all kinds of the equilibrium points are obtained. Sufficient conditions are established for the existence of backward bifurcation. The local asymptotical stability of equilibrium is verified by analyzing the eigenvalues and using the Routh-Hurwitz criterion. We also discuss the global asymptotical stability of the endemic equilibrium by autonomous convergence theorem. The study indicates that we should improve the efficiency and enlarge the capacity of the treatment to control the spread of disease. Numerical simulations are presented to support and complement the theoretical findings.


2017 ◽  
Vol 2017 ◽  
pp. 1-14 ◽  
Author(s):  
Eric Ávila-Vales ◽  
Erika Rivero-Esquivel ◽  
Gerardo Emilio García-Almeida

We consider a family of periodic SEIRS epidemic models with a fairly general incidence rate of the form Sf(I), and it is shown that the basic reproduction number determines the global dynamics of the models and it is a threshold parameter for persistence of disease. Numerical simulations are performed using a nonlinear incidence rate to estimate the basic reproduction number and illustrate our analytical findings.


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