scholarly journals Analysis of Human Gut Microbiota Composition Associated to the Presence of Commensal and Pathogen Microorganisms in Côte d’Ivoire

2021 ◽  
Vol 9 (8) ◽  
pp. 1763
Author(s):  
Veronica Di Cristanziano ◽  
Fedja Farowski ◽  
Federica Berrilli ◽  
Maristella Santoro ◽  
David Di Cave ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Cote D'ivoire ◽  
Côte D’Ivoire ◽  
Enteric Pathogens ◽  
Microbiota Composition ◽  
Human Gut ◽  
Cote D’Ivoire ◽  
Human Gut Microbiota ◽  
Côte D'ivoire ◽  
Gut Microbiota Composition

Background: The human gut microbiota is a microbial ecosystem contributing to the maintenance of host health with functions related to immune and metabolic aspects. Relations between microbiota and enteric pathogens in sub-Saharan Africa are scarcely investigated. The present study explored gut microbiota composition associated to the presence of common enteric pathogens and commensal microorganisms, e.g., Blastocystis and Entamoeba species, in children and adults from semi-urban and non-urban localities in Côte d’Ivoire. Methods: Seventy-six stool samples were analyzed for microbiota composition by 16S rRDNA sequencing. The presence of adeno-, entero-, parechoviruses, bacterial and protozoal pathogens, Blastocystis, and commensal Entamoeba species, was analyzed by different molecular assays. Results: Twelve individuals resulted negative for any tested microorganisms, 64 subjects were positive for one or more microorganisms. Adenovirus, enterovirus, enterotoxigenic Escherichia coli (ETEC), and Blastocystis were frequently detected. Conclusions: The bacterial composition driven by Prevotellaceae and Ruminococcaceae confirmed the biotype related to the traditional dietary and cooking practices in low-income countries. Clear separation in UniFrac distance in subjects co-harboring Entamoeba hartmanni and Blastocystis was evidenced. Alpha diversity variation in negative control group versus only Blastocystis positive suggested its possible regulatory contribution on intestinal microbiota. Pathogenic bacteria and virus did not affect the positive outcome of co-harbored Blastocystis.

Changes in Human Gut Microbiota Composition Are Linked to the Energy Metabolic Switch During Ten Days of Fasting

2019 ◽  
Author(s):  
Robin Mesnage ◽  
Franziska Grundler ◽  
Andreas Schwiertz ◽  
Yvon Le Maho ◽  
Françoise Wilhelmi de Toledo
Keyword(s):  
Gut Microbiota ◽  
Microbiota Composition ◽  
Human Gut ◽  
Metabolic Switch ◽  
Human Gut Microbiota ◽  
Gut Microbiota Composition

scholarly journals Sex differences in the phylum‐level human gut microbiota composition

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Alexander Koliada ◽  
Vladislav Moseiko ◽  
Mariana Romanenko ◽  
Oleh Lushchak ◽  
Nadiia Kryzhanovska ◽  
...  
Keyword(s):  
Sex Differences ◽  
Gut Microbiota ◽  
Age Groups ◽  
Microbiota Composition ◽  
Human Gut ◽  
Cross Sectional ◽  
Total N ◽  
Human Gut Microbiota ◽  
Gut Microbiota Composition

Abstract Background Evidence was previously provided for sex-related differences in the human gut microbiota composition, and sex-specific discrepancy in hormonal profiles was proposed as a main determinant of these differences. On the basis of these findings, the assumption was made on the role of microbiota in the sexual dimorphism of human diseases. To date, sex differences in fecal microbiota were demonstrated primarily at lower taxonomic levels, whereas phylum-level differences between sexes were reported in few studies only. In the present population-based cross-sectional research, sex differences in the phylum-level human gut microbiota composition were identified in a large (total n = 2301) sample of relatively healthy individuals from Ukraine. Results Relative abundances of Firmicutes and Actinobacteria, as determined by qRT-PCR, were found to be significantly increased, while that of Bacteroidetes was significantly decreased in females compared to males. The Firmicutes to Bacteroidetes (F/B) ratio was significantly increased in females compared to males. Females had 31 % higher odds of having F/B ratio more than 1 than males. This trend was evident in all age groups. The difference between sexes was even more pronounced in the elder individuals (50+): in this age group, female participants had 56 % higher odds of having F/B ratio > 1 than the male ones. Conclusions In conclusion, sex-specific differences in the phylum-level intestinal microbiota composition were observed in the Ukraine population. The F/B ratio was significantly increased in females compared to males. Further investigation is needed to draw strong conclusions regarding the mechanistic basis for sex-specific differences in the gut microbiota composition and regarding the role of these differences in the initiation and progression of human chronic diseases.

scholarly journals Effects of phlorotannin and polysaccharide fractions of brown seaweed Silvetia compressa on human gut microbiota composition using an in vitro colonic model

2021 ◽  
Vol 84 ◽  
pp. 104596
Author(s):  
Benjamín Vázquez-Rodríguez ◽  
Liliana Santos-Zea ◽  
Erick Heredia-Olea ◽  
Laura Acevedo-Pacheco ◽  
Arlette Santacruz ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Brown Seaweed ◽  
Microbiota Composition ◽  
Human Gut ◽  
Human Gut Microbiota ◽  
Gut Microbiota Composition

The effect of various diets on the human gut microbiota composition

2021 ◽  
Vol 70 (7) ◽  
pp. 5-10
Author(s):  
K.A. Aitbaev ◽  
I.T. Murkamilov ◽  
V.V. Fomin ◽  
Zh.A. Murkamilova ◽  
I.O. Kudaibergenova ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Microbiota Composition ◽  
Human Gut ◽  
Human Gut Microbiota ◽  
Gut Microbiota Composition

scholarly journals Effects of Commercial Apple Varieties on Human Gut Microbiota Composition and Metabolic Output Using an In Vitro Colonic Model

Nutrients ◽  
2017 ◽  
Vol 9 (6) ◽  
pp. 533 ◽  
Author(s):  
Athanasios Koutsos ◽  
Maria Lima ◽  
Lorenza Conterno ◽  
Mattia Gasperotti ◽  
Martina Bianchi ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Microbiota Composition ◽  
Human Gut ◽  
Apple Varieties ◽  
Human Gut Microbiota ◽  
Metabolic Output ◽  
Gut Microbiota Composition

scholarly journals The effects of iron fortification on the gut microbiota in African children: a randomized controlled trial in Côte d'Ivoire

2010 ◽  
Vol 92 (6) ◽  
pp. 1406-1415 ◽  
Author(s):  
Michael B Zimmermann ◽  
Christophe Chassard ◽  
Fabian Rohner ◽  
Eliézer K N'Goran ◽  
Charlemagne Nindjin ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Gut Microbiota ◽  
Cote D'ivoire ◽  
Côte D’Ivoire ◽  
Controlled Trial ◽  
Iron Fortification ◽  
Cote D’Ivoire ◽  
Randomized Controlled ◽  
African Children ◽  
Côte D'ivoire

scholarly journals Application of Luminex Gastrointestinal Pathogen Panel to human stool samples from Côte d’Ivoire

2015 ◽  
Vol 9 (08) ◽  
pp. 884-889 ◽  
Author(s):  
Veronica Di Cristanziano ◽  
Monika Timmen-Wego ◽  
Nadine Lübke ◽  
Rolf Kaiser ◽  
Herbert Pfister ◽  
...  
Keyword(s):  
Developing Countries ◽  
Cote D'ivoire ◽  
Côte D’Ivoire ◽  
Enteric Pathogens ◽  
Molecular Diagnostic ◽  
Cote D’Ivoire ◽  
Côte D'ivoire ◽  
Gastrointestinal Pathogen ◽  
Stool Samples ◽  
Asymptomatic Subjects

Introduction: Gastrointestinal infections caused by viruses, bacteria, and parasites are endemic in most developing countries due to inadequate provision of safe water supplies, sanitation, and hygiene. To investigate the enteric pathogens infecting people living in Côte d’Ivoire, the Luminex Gastrointestinal Pathogen Panel (xTAG GPP) assay was used to analyze 34 human fecal samples. This study represents the first application of this technology to samples from a sub-Saharan African country. Methodology: Thirty-four stool samples from asymptomatic and symptomatic patients, 1–15 years of age, were analyzed by xTAG GPP. The Luminex assay represents a qualitative bead-based multiplexed molecular diagnostic test able to identify concurrently 15 enteric pathogens, including bacteria, viruses, and parasites. Results: Overall, 22 out of 34 (64.7%) fecal specimens were detected to be positive by xTAG GPP. Sixteen were from asymptomatic subjects, and 10 patients (45.4%) showed co-infections. G. duodenalis was detected in 15 patients, in both mono- and co-infections, representing the most frequent pathogen, followed by enterotoxigenic Escherichia coli (ETEC) LT/ST. Four norovirus isolates were also detected and assigned to genogroups I and II. Conclusions: Considering the burden of enteric infections in developing countries, particularly among children, and the high rate of co-infections in asymptomatic subjects, this study shows the need for diagnostic tools such as xTAG GPP to improve diagnosis and treatment of these infections in endemic areas.

The effect of diet on the fluctuations of human gut microbiota

MedPharmRes ◽  
2019 ◽  
Vol 3 (1) ◽  
pp. 22-24
Author(s):  
Binh Nguyen
Keyword(s):  
Individual Differences ◽  
Gut Microbiota ◽  
Microbiota Composition ◽  
Human Gut ◽  
Human Gut Microbiota ◽  
The Individual ◽  
Gut Microbiota Composition

It was previously thought that the establishment of the gut microbiota was completed within the first two years of life, and this community maintains fairly stable throughout the adult lifetime thereafter. However, recent evidence shows that the gut microbiota composition is constantly changing in the gut environment and is heavily influenced by diet. The individual differences responding to diets would root on the fluctuations of gut microbiota if dietary fluctuations affect the composition of gut microbiota so significantly.

scholarly journals Close social relationships correlate with human gut microbiota composition

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Kimberly A. Dill-McFarland ◽  
Zheng-Zheng Tang ◽  
Julia H. Kemis ◽  
Robert L. Kerby ◽  
Guanhua Chen ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Social Relationships ◽  
Microbiota Composition ◽  
Human Gut ◽  
Human Gut Microbiota ◽  
Gut Microbiota Composition
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