Overview of the Antioxidant and Anti-Inflammatory Activities of Selected Plant Compounds and Their Metal Ions Complexes

Numerous plant compounds and their metal-ion complexes exert antioxidative, anti-inflammatory, anticancer, and other beneficial effects. This review highlights the different bioactivities of flavonoids, chromones, and coumarins and their metal-ions complexes due to different structural characteristics. In addition to insight into the most studied antioxidative properties of these compounds, the first part of the review provides a comprehensive overview of exogenous and endogenous sources of reactive oxygen and nitrogen species, oxidative stress-mediated damages of lipids and proteins, and on protective roles of antioxidant defense systems, including plant-derived antioxidants. Additionally, the review covers the anti-inflammatory and antimicrobial activities of flavonoids, chromones, coumarins and their metal-ion complexes which support its application in medicine, pharmacy, and cosmetology.

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Metal Ions in Biological Systems. Volume 32. Interactions of metal ions with nucleotides, nucleic acids, and their constituents A. Sigel and H. Sigel, Eds. Marcel Dekker Inc., New York. 1996. xxxix + 814 pp. 16 × 23.5 cm. ISBN 0-8247-99549-0. $225.00.Metal Ions in Biological Systems.Volume 33.Probing of nucleic acids by metal ion complexes of small molecules.A. Sigel and H. Sigel, Eds. Marcel Dekker Inc., New York. 1996. xli + 678 pp. 16 × 23.5 cm. ISBN 0-8247-9688-8. $195.00.

Journal of Medicinal Chemistry ◽

10.1021/jm960473+ ◽

1996 ◽

Vol 39 (21) ◽

pp. 4346-4346 ◽

Cited By ~ 2

Author(s):

J. A. Cowan

Keyword(s):

New York ◽

Nucleic Acids ◽

Metal Ions ◽

Metal Ion ◽

Biological Systems ◽

Metal Ion Complexes

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Quantitative Evaluation of Lewis Acidity of Metal Ions Derived from theg Values of ESR Spectra of Superoxide: Metal Ion Complexes in Relation to the Promoting Effects in Electron Transfer Reactions

Chemistry - A European Journal ◽

10.1002/1521-3765(20001215)6:24<4532::aid-chem4532>3.0.co;2-9 ◽

2000 ◽

Vol 6 (24) ◽

pp. 4532-4535 ◽

Cited By ~ 129

Author(s):

Shunichi Fukuzumi ◽

Kei Ohkubo

Keyword(s):

Electron Transfer ◽

Metal Ions ◽

Quantitative Evaluation ◽

Metal Ion ◽

Esr Spectra ◽

Transfer Reactions ◽

Lewis Acidity ◽

Metal Ion Complexes ◽

Electron Transfer Reactions

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Synthesis and Spectral Analysis of Some Metal Ions Complexes with Mixed Ligands of Schiff Base and 1, 10-Phenanthroline

Baghdad Science Journal ◽

10.21123/bsj.14.1.135-147 ◽

2017 ◽

Vol 14 (1) ◽

pp. 135-147

Author(s):

Baghdad Science Journal

Keyword(s):

Schiff Base ◽

Metal Ions ◽

Metal Complexes ◽

Mass Spectrometer ◽

Schiff Base Ligand ◽

Metal Ion ◽

Molecular Structures ◽

Spectroscopic Techniques ◽

Metal Ion Complexes ◽

Free Schiff Base

The free Schiff base ligand (HL1) is prepared by being mixed with the co-ligand 1, 10-phenanthroline (L2). The product then is reacted with metal ions: (Cr+3, Fe+3, Co+2, Ni+2, Cu+2 and Cd+2) to get new metal ion complexes. The ligand is prepared and its metal ion complexes are characterized by physic-chemical spectroscopic techniques such as: FT-IR, UV-Vis, spectra, mass spectrometer, molar conductivity, magnetic moment, metal content, chloride content and microanalysis (C.H.N) techniques. The results show the formation of the free Schiff base ligand (HL1). The fragments of the prepared free Schiff base ligand are identified by the mass spectrometer technique. All the analysis of ligand and its metal complexes are in good agreement with the theoretical values indicating the purity of Schiff base ligand and the metal complexes. From the above data, the molecular structures for all the metal complexes are proposed to be octahedral

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