scholarly journals Structure, Bioactivity and Analytical Methods for the Determination of Yucca Saponins

Molecules ◽  
2021 ◽  
Vol 26 (17) ◽  
pp. 5251
Author(s):  
Gabriel G. Jiménez ◽  
Alexandra G. Durán ◽  
Francisco A. Macías ◽  
Ana M. Simonet

Yucca is one of the main sources of steroidal saponins, hence different extracts are commercialized for use as surfactant additives by beverage, animal feed, cosmetics or agricultural products. For a deeper understanding of the potential of the saponins that can be found in this genus, an exhaustive review of the structural characteristics, bioactivities and analytical methods that can be used with these compounds has been carried out, since there are no recent reviews on the matter. Thus, a total of 108 saponins from eight species of the genus Yucca have been described. Out of these, the bioactivity of 68 saponins derived from the isolation of Yucca or other genera has been evaluated. Regarding the evaluation and quality control of the saponins from this genus LC-MS technique is the most often used. Nevertheless, the development of methods for their routine analysis in commercial preparations are needed. Moreover, most of the studies found in the literature have been carried out on Y. schidigera extract, since is the most often used for commercial purposes. Only eight of the 50 species that belong to this genus have been studied, which clearly indicates that the identification of saponins present in Yucca genus is still an unresolved question.

2019 ◽  
Vol 102 (3) ◽  
pp. 801-809
Author(s):  
Ana Carolina Kogawa ◽  
Ana Elisa Della Torre Pires ◽  
Hérida Regina Nunes Salgado

Abstract Background: Atorvastatin, a lipid-regulating drug, was the best-selling drug in the world in the early 2000s. Thus, monitoring of this drug is important because it is accessible to a large portion of the population. In addition, its quality control is fundamental to provide quality medicines. Method of analysis can be the first step in the rational use of pharmaceuticals. Objective/Methods: In this context, a critical review of analytical methods present in the literature and official compendia for the pharmaceutical quality control of atorvastatin was made. Results: Among the analytical methods most used in the evaluation of atorvastatin, HPLC is highlighted, followed by HPLC coupled to MS, and spectrophotometry in UV. Tablets are the most studied pharmaceutical samples, and plasma is the most studied biological matrix. In the literature, studies with atorvastatin-based pharmaceutical products are more common than biological materials. Acetonitrile is the organic solvent most commonly used in the methods surveyed to evaluate atorvastatin. Conclusions: Currently, awareness of the impact that the analytical choice has on the health of the operator and the environment is growing. Therefore, the suitability of existing methods for the determination of atorvastatin can be made to adhere to the current analytical chemistry. In this way, the analytical, environmental, and human consciousness will remain united. Highlights: Although the literature shows interesting methods from an economic and environmental point of view, such as UV, Vis miniaturized, and TLC, they can still be improved to meet the requirements of the current sustainable analytical chemistry.


Author(s):  
L.N. Chervyakova ◽  
T.P. Panchenko ◽  
N.M. Adamenko

The method of determination of phosphorous acid and aluminum phosphite photometric method which allows to evaluate the mass fraction of active substances in the grain of corn and sunflower seeds, and gives the ability to control their content at the level of hygienic standards.


2016 ◽  
Vol 7 (2) ◽  
pp. 143
Author(s):  
Julio Cesar Freitas Santos ◽  
Lumena Cunha Mendes ◽  
Jessica Almeida Correa ◽  
Juarez Fabiano Alkmim Filho ◽  
Danilo Vicente Reis da Silva ◽  
...  

The analysis of roast and ground coffee sediment is part of product quality control procedures. The aim of this study was to validate a methodology for determining sediment in roasted and ground coffee based on the principle of sedimentation with the use of organic solvent. A set of 30 samples of product was fortified in five increasing levels of sediments, 0.4%, 0.8%, 1.2%, 1.6% and 3% and analyzed in duplicate by two operators, totaling 120 results. In the evaluation of accuracy in repeatability and intermediate conditions dispersion index was obtained in a suitable range, below 20%, suitable for use. The accuracy and precision of the method were considered satisfactory, and the uncertainty below 15%, proving appropriateness of using the method for routine analysis in the determination of sediments in roasted and ground coffee.


Chemosphere ◽  
1996 ◽  
Vol 32 (1) ◽  
pp. 31-44 ◽  
Author(s):  
Rainer Malisch ◽  
Peter Schmid ◽  
Rolf Frommberger ◽  
Peter Fürst

2010 ◽  
Vol 8 (3) ◽  
pp. 377-379 ◽  
Author(s):  
Lestyo Wulandari

An accurate and sensitive HPLC method has been developed for the determination of mebhydroline napadisylate in the tablet. The Chromatography was performed on a reversed phase C-18 column, using a mobile phase of acetonitrile : ammonia 25% (80 : 20 v/v) at ambient temperature 25±5 °C and UV detection operates at 320 nm in an overall analysis time of about 15 min, based on peak area. This HPLC method is selective, precise, and accurate and can be used for routine analysis of pharmaceutical preparation in industrial quality-control laboratories.   Keywords : HPLC, mebhydroline napadisylate, validation


2012 ◽  
Vol 2 (8) ◽  
pp. 66-68
Author(s):  
Shreya Nayak ◽  
◽  
Sanjay Pai P.N. Sanjay Pai P.N.
Keyword(s):  

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