scholarly journals Recent Progress in Metal–Organic Framework (MOF) Based Luminescent Chemodosimeters

Nanomaterials ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. 974 ◽  
Author(s):  
Hao ◽  
Chen ◽  
Zhou ◽  
Zhang ◽  
Xu
Keyword(s):  
Photophysical Properties ◽  
Metal Organic Framework ◽  
Organic Ligands ◽  
Future Perspectives ◽  
Fluoride Ions ◽  
Luminescent Sensors ◽  
Sensing Applications ◽  
Redox Active ◽  
Metal Organic ◽  
Luminescent Sensing

Metal–organic frameworks (MOFs), as a class of crystalline hybrid architectures, consist of metal ions and organic ligands and have displayed great potential in luminescent sensing applications due to their tunable structures and unique photophysical properties. Until now, many studies have been reported on the development of MOF-based luminescent sensors, which can be classified into two major categories: MOF chemosensors based on reversible host–guest interactions and MOF chemodosimeters based on the irreversible reactions between targets with a probe. In this review, we summarize the recently developed luminescent MOF-based chemodosimeters for various analytes, including H2S, HClO, biothiols, fluoride ions, redox-active biomolecules, Hg2+, and CN−. In addition, some remaining challenges and future perspectives in this area are also discussed.

Strategies to fabricate metal–organic framework (MOF)-based luminescent sensing platforms

2019 ◽  
Vol 7 (35) ◽  
pp. 10743-10763 ◽  
Author(s):  
Yang Liu ◽  
Xiao-Yu Xie ◽  
Chen Cheng ◽  
Zhen-Shu Shao ◽  
Huai-Song Wang
Keyword(s):  
Chemical Sensing ◽  
Metal Organic Framework ◽  
Luminescent Sensors ◽  
Sensing Platforms ◽  
Metal Organic ◽  
Luminescent Sensing ◽  
Organic Framework

This review introduces the recent advance in the construction of MOF-based sensing platforms in chemical sensing and biosensing. In particular, the fabricating strategies of MOF-based luminescent sensors and the sensing mechanisms are reviewed.

scholarly journals Cation-induced chirality in a bifunctional metal-organic framework for quantitative enantioselective recognition

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Zongsu Han ◽  
Kunyu Wang ◽  
Yifan Guo ◽  
Wenjie Chen ◽  
Jiale Zhang ◽  
...  
Keyword(s):  
Metal Organic Framework ◽  
Metal Organic Frameworks ◽  
Chiral Molecules ◽  
Enantioselective Recognition ◽  
Luminescent Sensors ◽  
Metal Organic ◽  
Luminescent Centers ◽  
Luminescent Sensing ◽  
Organic Framework

Abstract The integration of luminescence and chirality in easy-scalable metal-organic frameworks gives rise to the development of advanced luminescent sensors. To date, the synthesis of chiral metal-organic frameworks is poorly predictable and their chirality primarily originates from components that constitute the frameworks. By contrast, the introduction of chirality into the pores of metal-organic frameworks has not been explored to the best of our knowledge. Here, we demonstrate that chirality can be introduced into an anionic Zn-based metal-organic framework via simple cation exchange, yielding dual luminescent centers comprised of the ligand and Tb3+ ions, accompanied by a chiral center in the pores. This bifunctional material shows enantioselectivity luminescent sensing for a mixture of stereoisomers, demonstrated for Cinchonine and Cinchonidine epimers and amino alcohol enantiomers, from which the quantitative determination of the stereoisomeric excess has been obtained. This study paves a pathway for the design of multifunctional metal-organic framework systems as a useful method for rapid sensing of chiral molecules.

scholarly journals Exciton Coupling and Conformational Changes Impacting the Excited State Properties of Metal Organic Frameworks

Molecules ◽  
2020 ◽  
Vol 25 (18) ◽  
pp. 4230
Author(s):  
Andreas Windischbacher ◽  
Luca Steiner ◽  
Ritesh Haldar ◽  
Christof Wöll ◽  
Egbert Zojer ◽  
...  
Keyword(s):  
Conformational Changes ◽  
Photophysical Properties ◽  
Metal Organic Framework ◽  
Metal Organic Frameworks ◽  
Red Shift ◽  
Light Emitting ◽  
Light Emitting Devices ◽  
Exciton Coupling ◽  
Metal Organic ◽  
Crystalline Metal

In recent years, the photophysical properties of crystalline metal-organic frameworks (MOFs) have become increasingly relevant for their potential application in light-emitting devices, photovoltaics, nonlinear optics and sensing. The availability of high-quality experimental data for such systems makes them ideally suited for a validation of quantum mechanical simulations, aiming at an in-depth atomistic understanding of photophysical phenomena. Here we present a computational DFT study of the absorption and emission characteristics of a Zn-based surface-anchored metal-organic framework (Zn-SURMOF-2) containing anthracenedibenzoic acid (ADB) as linker. Combining band-structure and cluster-based simulations on ADB chromophores in various conformations and aggregation states, we are able to provide a detailed explanation of the experimentally observed photophysical properties of Zn-ADB SURMOF-2: The unexpected (weak) red-shift of the absorption maxima upon incorporating ADB chromophores into SURMOF-2 can be explained by a combination of excitonic coupling effects with conformational changes of the chromophores already in their ground state. As far as the unusually large red-shift of the emission of Zn-ADB SURMOF-2 is concerned, based on our simulations, we attribute it to a modification of the exciton coupling compared to conventional H-aggregates, which results from a relative slip of the centers of neighboring chromophores upon incorporation in Zn-ADB SURMOF-2.

scholarly journals Nanomedicine-Based Strategies Assisting Photodynamic Therapy for Hypoxic Tumors: State-of-the-Art Approaches and Emerging Trends

Biomedicines ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 137
Author(s):  
Chun-Yan Shih ◽  
Pei-Ting Wang ◽  
Wu-Chou Su ◽  
Hsisheng Teng ◽  
Wei-Lun Huang
Keyword(s):  
Photodynamic Therapy ◽  
State Of The Art ◽  
Metal Organic Framework ◽  
Basic Knowledge ◽  
Future Perspectives ◽  
Effective Strategies ◽  
Emerging Trends ◽  
Tumor Tissues ◽  
Metal Organic ◽  
Manipulating Hypoxia

Since the first clinical cancer treatment in 1978, photodynamic therapy (PDT) technologies have been largely improved and approved for clinical usage in various cancers. Due to the oxygen-dependent nature, the application of PDT is still limited by hypoxia in tumor tissues. Thus, the development of effective strategies for manipulating hypoxia and improving the effectiveness of PDT is one of the most important area in PDT field. Recently, emerging nanotechnology has benefitted progress in many areas, including PDT. In this review, after briefly introducing the mechanisms of PDT and hypoxia, as well as basic knowledge about nanomedicines, we will discuss the state of the art of nanomedicine-based approaches for assisting PDT for treating hypoxic tumors, mainly based on oxygen replenishing strategies and the oxygen dependency diminishing strategies. Among these strategies, we will emphasize emerging trends about the use of nanoscale metal–organic framework (nMOF) materials and the combination of PDT with immunotherapy. We further discuss future perspectives and challenges associated with these trends in both the aspects of mechanism and clinical translation.

scholarly journals The nanoscaled metal-organic framework ICR-2 as a carrier of porphyrins for photodynamic therapy

2018 ◽  
Vol 9 ◽  
pp. 2960-2967 ◽  
Author(s):  
Jan Hynek ◽  
Sebastian Jurík ◽  
Martina Koncošová ◽  
Jaroslav Zelenka ◽  
Ivana Křížová ◽  
...  
Keyword(s):  
Inorganic Chemistry ◽  
Photodynamic Therapy ◽  
Photophysical Properties ◽  
Metal Organic Framework ◽  
Metal Organic Frameworks ◽  
Biological Applications ◽  
Nanoparticle Surface ◽  
Metal Organic ◽  
Unsaturated Metal Sites ◽  
First Time

Nanosized porphyrin-containing metal-organic frameworks (MOFs) attract considerable attention as solid-state photosensitizers for biological applications. In this study, we have for the first time synthesised and characterised phosphinate-based MOF nanoparticles, nanoICR-2 (Inorganic Chemistry Rez). We demonstrate that nanoICR-2 can be decorated with anionic 5,10,15,20-tetrakis(4-R-phosphinatophenyl)porphyrins (R = methyl, isopropyl, phenyl) by utilizing unsaturated metal sites on the nanoparticle surface. The use of these porphyrins allows for superior loading of the nanoparticles when compared with commonly used 5,10,15,20-tetrakis(4-carboxyphenyl)porphyrin. The nanoICR-2/porphyrin composites retain part of the free porphyrins photophysical properties, while the photodynamic efficacy is strongly affected by the R substituent at the porphyrin phosphinate groups. Thus, phosphinatophenylporphyrin with phenyl substituents has the strongest photodynamic efficacy due to the most efficient cellular uptake.

Anisotropy in Metal-Organic Framework Thin Films

2021 ◽  
Author(s):  
Zahra Rahmati ◽  
Ruhollah Khajavian ◽  
Masoud Mirzaei
Keyword(s):  
Thin Films ◽  
Porous Materials ◽  
Metal Organic Framework ◽  
Organic Ligands ◽  
Metal Organic ◽  
Organic Framework

MOF thin films are a gigantic category of porous materials composed of organic ligands in connection with metallic nodes. The fabrication of specifically oriented MOF films on surfaces has drawn...

Mechanistic insights into the luminescent sensing of nitrophenol compounds by a cationic Zn-based metal-organic framework

2022 ◽  
pp. 110099
Author(s):  
Yuhang Liu ◽  
Yaohui Wang ◽  
Yi Zhang ◽  
Pran Gopal Karmaker ◽  
Lilei Zhang ◽  
...  
Keyword(s):  
Metal Organic Framework ◽  
Metal Organic ◽  
Luminescent Sensing ◽  
Organic Framework
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