scholarly journals Eicosapentaenoic Acid (EPA) and Docosahexaneoic Acid (DHA) in Muscle Damage and Function

Nutrients ◽  
2018 ◽  
Vol 10 (5) ◽  
pp. 552 ◽  
Author(s):  
Eisuke Ochi ◽  
Yosuke Tsuchiya
Keyword(s):  
Fatty Acids ◽  
Eicosapentaenoic Acid ◽  
Muscle Damage ◽  
Animal Studies ◽  
Inflammatory Responses ◽  
Endurance Performance ◽  
Optimal Dose ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
And Function

Nutritional supplementation not only helps in improving and maintaining performance in sports and exercise, but also contributes in reducing exercise fatigue and in recovery from exhaustion. Fish oil contains large amounts of omega-3 fatty acids, eicosapentaenoic acid (EPA; 20:5 n-3) and docosahexaenoic acid (DHA; 22:6 n-3). It is widely known that omega-3 fatty acids are effective for improving cardiac function, depression, cognitive function, and blood as well as lowering blood pressure. In the relationship between omega-3 fatty acids and exercise performance, previous studies have been predicted improved endurance performance, antioxidant and anti-inflammatory responses, and effectivity against delayed-onset muscle soreness. However, the optimal dose, duration, and timing remain unclear. This review focuses on the effects of omega-3 fatty acid on muscle damage and function as evaluated by human and animal studies and summarizes its effects on muscle and nerve damage, and muscle mass and strength.

Recent progress on immobilization technology in enzymatic conversion of marine by-products to concentrated omega-3 fatty acids

2021 ◽  
Author(s):  
Yi Liu ◽  
Deepika Dave
Keyword(s):  
Fatty Acids ◽  
Docosahexaenoic Acid ◽  
Eicosapentaenoic Acid ◽  
Recent Progress ◽  
Enzymatic Conversion ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Immobilization Technology ◽  
By Products

Marine by-products (heads, frames, trimmings, viscera, skin and scales) have been extensively investigated as sources of marine omega-3 fatty acids (mainly eicosapentaenoic acid and docosahexaenoic acid). Traditionally, extraction of fish...

scholarly journals Rapeseeds a Rich Source of Polyunsaturated Fatty Acids

Proceedings ◽  
2019 ◽  
Vol 29 (1) ◽  
pp. 115
Author(s):  
Cristina Emanuela Enăşcuţă ◽  
Elena Emilia Oprescu ◽  
Adrian Radu ◽  
Elena Radu ◽  
Marian Deaconu ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Docosahexaenoic Acid ◽  
Polyunsaturated Fatty Acids ◽  
Eicosapentaenoic Acid ◽  
Stroke Prevention ◽  
Essential Role ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Human Diet ◽  
Brain Functions

In human diet, polyunsaturated fatty acids (PUFA), have an essential role in optimal brain functions and stroke prevention, specially, omega-3 fatty acids, e.g., 9,12,15-linolenic acid (ALA, 18:3), 5,8,11,14,17-eicosapentaenoic acid (EPA, 20:5), and 4,7,10,13,16,19-docosahexaenoic acid (DHA, 22:6). [...]

Effect of omega-3 fatty acids, docosahexaenoic and eicosapentaenoic, on norepinephrine-induced contractions

1992 ◽  
Vol 70 (5) ◽  
pp. 675-679 ◽  
Author(s):  
Mary B. Engler
Keyword(s):  
Fatty Acids ◽  
Docosahexaenoic Acid ◽  
Eicosapentaenoic Acid ◽  
Contractile Response ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Free Medium ◽  
Vascular Responses ◽  
Rat Thoracic Aorta ◽  
Docosahexaenoic Acids

The relaxant responses of the rat thoracic aorta to omega-3 fatty acids, docosahexaenoic and eicosapentaenoic, on norepinephrine- and potassium-induced contractions were investigated. Relaxation was enhanced in vessels contracted with norepinephrine. Docosahexaenoic acid at concentrations as low as 1, 3, and 10 μM evoked significant relaxant responses (15, 23, 30%) in norepinephrine-contracted vessels as compared with responses (5, 9, 12%) in potassium-contracted vessels. Results for eicosapentaenoic acid under similar conditions were 3, 8, and 19% in norepinephrine-contracted vessels and 3, 3, and 8% in potassium-contracted vessels. Pretreatment with eicosapentaenoic (10 μM) or docosahexaenoic acids (1–10 μM) decreased the contractile response to physiologic concentrations of norepinephrine. In the presence of calcium-free medium, the omega-3 fatty acids (1–30 μM) significantly abolished sustained norepinephrine contractions but did not reduce the phasic contractions when incubated prior to norepinephrine contraction. Comparatively, the effects of docosahexaenoic acid were greater than eicosapentaenoic acid. These findings suggest that the relaxant effects of the omega-3 fatty acids are specific to the mode of contraction, i.e., α-adrenoceptor stimuli. This effect may be related to intracellular calcium mechanisms, since both fatty acids reversed norepinephrine-induced sustained contractions in the absence of extracellular calcium.Key words: omega-3 polyunsaturated fatty acids, eicosapentaenoic acid, docosahexaenoic acid, vascular responses, fish oils.

Lack of effect of eicosapentaenoic acid in the Porsolt forced swimming test model of depression

2002 ◽  
Vol 14 (5) ◽  
pp. 203-206 ◽  
Author(s):  
Alona Shaldubina ◽  
Boris Nemets ◽  
Yuly Bersudsky
Keyword(s):  
Fatty Acids ◽  
Eicosapentaenoic Acid ◽  
Forced Swimming Test ◽  
Forced Swimming ◽  
Test Model ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Immobility Time ◽  
Swimming Test ◽  
Clinical Experiments

Background:Eicosapentaenoic acid (EPA) is one of the major components of fish oils. Omega-3 fatty acids, particularly EPA, have been hypothesized to play a role in the etiology, pathogenesis and treatment of mood disorders. Clinical studies have shown beneficial effects of omega-3 fatty acids in major depression, bipolar disorder and other psychiatric disorders.Objective:The present study design evaluates the effect of EPA in the Porsolt forced swimming test.Results:EPA alone did not reduce the immobility time and did not enhance the anti-immobility effect of a low dose of imipramine. Contrary to the hypothesis, EPA slightly increased the immobility time, and in some experiments tended to reduce the anti-despair effect of imipramine.Conclusion:The present results do not provide an animal model for the antidepressant effect of EPA as demonstrated in clinical experiments. The mechanism of EPA antidepressant action is unknown and the Porsolt forced swimming test could be non-sensitive for its antidepressant properties.

Mercury and Omega-3 Fatty Acids in Retail Fish Sandwiches

2005 ◽  
Vol 68 (3) ◽  
pp. 633-635 ◽  
Author(s):  
S. M. SHIM ◽  
J. A. LASRADO ◽  
L. E. DORWORTH ◽  
C. R. SANTERRE
Keyword(s):  
Fatty Acids ◽  
Docosahexaenoic Acid ◽  
Eicosapentaenoic Acid ◽  
Drug Administration ◽  
Food And Drug Administration ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Adequate Intake ◽  
Reference Dose

Mercury and fatty acids were measured in fish sandwiches from six retail restaurant chains. Average mercury concentrations ranged from 5 to 132 ppb and were well below the Food and Drug Administration action level (1,000 ppb). The average concentrations of eicosapentaenoic acid plus docosahexaenoic acid ranged from 91 to 620 mg per sandwich. Consuming one or two fish sandwiches per week could result in the consumption of 2 to 40% of the reference dose for mercury for a 60-kg individual and would provide 18 to 126% of the adequate intake for eicosapentaenoic acid plus docosahexaenoic acid as recommended for a pregnant or lactating woman.

Biomass Production and Fatty Acids Long Chain Polyunsaturated Omega 3 (LC-PUFAs) Chilean Strain Using Thraustochytrids

2015 ◽  
Vol 14 ◽  
pp. 23-28
Author(s):  
David Silva ◽  
Gabriel Cortínez ◽  
Benita H. Quilodrán
Keyword(s):  
Fatty Acids ◽  
Docosahexaenoic Acid ◽  
Eicosapentaenoic Acid ◽  
Fish Oil ◽  
Biomass Production ◽  
Single Cells ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Marine Protists ◽  
Long Chain

Global utilization of long-chain polyunsaturated fatty acids (LC-PUFAs) has increased steadily in the last decade which has imposed a huge demand for fish oil as it is currently the only source capable of sustaining the enormous commercial requirements this input worldwide. They are currently using various microorganisms to produce single cells oil (SCO) high in LC-PUFAs, within which highlights the thraustochytrids (TH). The TH is a group of marine protists (pseudofungi) with capacity to produce LC-PUFAs such as eicosapentaenoic acid (EPA), docosapentaenoic (DPA) and docosahexaenoic acid (DHA). In this study the chilean VAL-B1 strain was grown in glucose, starch and glycerol being obtained biomass production and LC-PUFAs. Biomass values ​​obtained were 1.02 ± 0.32 g/L, 1.25 ± 0.44 g/L and 1.44 ± 0.27 g/L of glucose, glycerol and starch respectively. The profile of LC-PUFAs showed a percentage of omega-3 fatty acids on glucose of 59.34%, 61.50% in starch and glycerol of 47.86%. The greater this value was to omega-3 DHA when starch was used, with 68.16 mg/g being greater than 45.77 mg/g glycerol and 63.89 mg/g in glucose. Therefore, we conclude that VAL-B1 produces more biomass has greater value of omega-3 LC-PUFAs and greater concentration of DHA when starch is used as a source of substrate for cultures.

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