scholarly journals Reply: “Comment on Search and Selection of Probiotics that Improve Mucositis Symptoms in Oncologic Patients. A Systematic Review. Nutrients 2019, 11, 2322”

Nutrients ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 401
Author(s):  
José Antonio Picó-Monllor ◽  
José Manuel Mingot-Ascencao

In the article, “Search and Selection of Probiotics That Improve Mucositis Symptoms in Oncologic Patients [...]

2021 ◽  
Vol 10 (12) ◽  
pp. e52101220170
Author(s):  
Daniela Santos Silva Ferreira de Almeida ◽  
Fernando Henrique Oliveira de Almeida ◽  
Izabella de Sousa Cristino ◽  
Carlos Adriano Santos Souza ◽  
Francilene Amaral da Silva

Objective: To describe the methodological steps to carry out a systematic review of pharmaceutical interventions for smoking cessation. Review Method: The protocol for this Systematic Review was developed according to the recommendations of the Prism P guidelines. Will be used as exclusion criteria: comments, editorials, articles that were not in Portuguese, Spanish, and English or articles that were not available in full. Also, articles indexed repeatedly in two or more databases will only be considered once. Two independent reviewers will evaluate titles, abstracts and full texts. Differences in selection will be resolved through a third reviewer. Discussion: This review will aim to critically synthesize the clinical evidence surrounding pharmaceutical interventions for smoking cessation, including data on ethnicity, age, socioeconomic conditions, level of health care, and the intervention environment. Therefore, the use of validated procedures and instruments to assess pharmaceutical interventions in support of smoking patients is essential. Conclusion: This protocol aims to describe the methodological steps to carry out a systematic review of pharmaceutical interventions for smoking cessation, aiming to reduce biases in the search and selection of references, making these criteria clear and uniform among reviewers.


Author(s):  
Maria Ciaramella ◽  
Nadia Monacelli ◽  
Livia Concetta Eugenia Cocimano

AbstractThis systematic review aimed to contribute to a better and more focused understanding of the link between the concept of resilience and psychosocial interventions in the migrant population. The research questions concerned the type of population involved, definition of resilience, methodological choices and which intervention programmes were targeted at migrants. In the 90 articles included, an heterogeneity in defining resilience or not well specified definition resulted. Different migratory experiences were not adequately considered in the selection of participants. Few resilience interventions on migrants were resulted. A lack of procedure’s descriptions that keep in account specific migrants’ life-experiences and efficacy’s measures were highlighted.


2019 ◽  
Vol 26 (5) ◽  
pp. 462-478 ◽  
Author(s):  
Tsung-Ting Kuo ◽  
Hugo Zavaleta Rojas ◽  
Lucila Ohno-Machado

Abstract Objectives To introduce healthcare or biomedical blockchain applications and their underlying blockchain platforms, compare popular blockchain platforms using a systematic review method, and provide a reference for selection of a suitable blockchain platform given requirements and technical features that are common in healthcare and biomedical research applications. Target audience Healthcare or clinical informatics researchers and software engineers who would like to learn about the important technical features of different blockchain platforms to design and implement blockchain-based health informatics applications. Scope Covered topics include (1) a brief introduction to healthcare or biomedical blockchain applications and the benefits to adopt blockchain; (2) a description of key features of underlying blockchain platforms in healthcare applications; (3) development of a method for systematic review of technology, based on the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement, to investigate blockchain platforms for healthcare and medicine applications; (4) a review of 21 healthcare-related technical features of 10 popular blockchain platforms; and (5) a discussion of findings and limitations of the review.


2005 ◽  
Vol 8 (1) ◽  
pp. 21-28 ◽  
Author(s):  
Gill Cowburn ◽  
Lynn Stockley

AbstractObjective:To explore published and unpublished research into consumer understanding and use of nutrition labelling which is culturally applicable in Europe.Design:A systematic review undertaken between July 2002 and February 2003.Results:One hundred and three papers were identified that reported on consumer understanding or use of nutrition labelling, most originating from North America or northern Europe. Only a few studies (9%) were judged to be of high or medium–high quality. We found that reported use of nutrition labels is high but more objective measures suggest that actual use of nutrition labelling during food purchase may be much lower. Whether or not consumers can understand and use nutrition labelling depends on the purpose of the task. Available evidence suggests that consumers who do look at nutrition labels can understand some of the terms used but are confused by other types of information. Most appear able to retrieve simple information and make simple calculations and comparisons between products using numerical information, but their ability to interpret the nutrition label accurately reduces as the complexity of the task increases. The addition of interpretational aids like verbal descriptors and recommended reference values helps in product comparison and in putting products into a total diet context.Conclusions:Improvements in nutrition labelling could make a small but important contribution towards making the existing point-of-purchase environment more conducive to the selection of healthy choices. In particular, interpretational aids can help consumers assess the nutrient contribution of specific foods to the overall diet.


ScientiaTec ◽  
2020 ◽  
Vol 7 (03) ◽  
Author(s):  
Giandra Volpato ◽  
Victória Furtado Migliavacca ◽  
Bruna Coelho de Andrade ◽  
Júlio Xandro Heck ◽  
Marco Antônio Záchia Ayub

The industrial application of lipolytic enzymes has been studied mainly due to the ability of these enzymes in catalyze reactions of synthesis and their stability in various organic solvents. One possibility is the use of lipase the organic synthesis, taking advantage as the generation of waste and difficult recovery of sub bioproducts. In this work, we carried out a selection of eighty-four isolates of Bacillus amazonian for lipase production, of which 30 strains showed lipolytic activity. The study of the culture conditions was performed through a Plackett-Burman experimental design using the strain that presented the highest lipolytic activity in a culture medium using glycerol as substrate.  The studied conditions were: concentration of soybean oil, olive oil, triton X-100, gum arabic, glycerol, and (NH4)2SO4, pH, temperature and concentration of inoculums. The best result obtained were 27 U/L in 48 h of cultivation by Bacillus circulans BL53. This work shows that the search and selection of microorganism with lipolytic activities can facilitate the discovery of new lipases, with potential use as by-product surplus.


2019 ◽  
Vol 6 (10) ◽  
Author(s):  
Chitra Punjabi ◽  
Vivian Tien ◽  
Lina Meng ◽  
Stan Deresinski ◽  
Marisa Holubar

Abstract Background Using published data, we sought to compare outcomes in patients transitioned to either oral fluoroquinolones (FQs) or trimethoprim-sulfamethoxazole (TMP-SMX) vs ß-lactams (BLs) after an initial intravenous (IV) course for gram-negative rod (GNR) bacteremia. Methods We conducted a systematic review of PubMed and EMBASE and published IDWeek abstracts. We included studies that reported all-cause mortality and/or infection recurrence in patients transitioned to oral FQ/TMP-SMX and BLs. Results Eight retrospective studies met inclusion criteria with data for 2289 patients, of whom 65% were transitioned to oral FQs, 7.7% to TMP-SMX, and 27.2% to BLs. Follow-up periods ranged from 21 to 90 days. All-cause mortality was not significantly different between patients transitioned to either FQ/TMP-SMX or BLs (odds ratio [OR], 1.13; 95% confidence interval [CI], 0.69–1.87). Overall recurrence of infection, either bacteremia or the primary site, occurred more frequently in patients transitioned to oral BLs vs FQs (OR, 2.05; 95% CI, 1.17–3.61). Analysis limited to recurrent bacteremia was similarly suggestive, although limited by small numbers (OR, 2.15; 95% CI, 0.93–4.99). However, based on known pharmacokinetics/pharmacodynamics, prescribed ß-lactam dosing regimens were frequently suboptimal. Conclusions In the step-down IV to oral treatment of GNR bacteremia, we found insufficient data regarding outcomes after oral TMP-SMX; however, selection of an FQ over commonly utilized ß-lactam regimens may reduce chances of infection recurrence. Although this may be a class effect, it may simply be the result of inadequate dosing of ß-lactams. Additional investigations are warranted to determine outcomes with TMP-SMX and optimized oral ß-lactam dosing regimens.


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