scholarly journals Nutrition in Gynecological Diseases: Current Perspectives

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1178
Author(s):  
Michał Ciebiera ◽  
Sahar Esfandyari ◽  
Hiba Siblini ◽  
Lillian Prince ◽  
Hoda Elkafas ◽  
...  
Keyword(s):  
Health Management ◽  
Negative Impact ◽  
Malignant Tumors ◽  
Polycystic Ovary ◽  
Uterine Fibroids ◽  
Nutrient Deficiency ◽  
Gynecological Diseases ◽  
Beneficial Impact ◽  
Bibliographic Search

Diet and nutrition are fundamental in maintaining the general health of populations, including women’s health. Health status can be affected by nutrient deficiency and vice versa. Gene–nutrient interactions are important contributors to health management and disease prevention. Nutrition can alter gene expression, as well as the susceptibility to diseases, including cancer, through several mechanisms. Gynecological diseases in general are diseases involving the female reproductive system and include benign and malignant tumors, infections, and endocrine diseases. Benign diseases such as uterine fibroids and endometriosis are common, with a negative impact on women’s quality of life, while malignant tumors are among the most common cause of death in the recent years. In this comprehensive review article, a bibliographic search was performed for retrieving information about nutrients and how their deficiencies can be associated with gynecological diseases, namely polycystic ovary syndrome, infertility, uterine fibroids, endometriosis, dysmenorrhea, and infections, as well as cervical, endometrial, and ovarian cancers. Moreover, we discussed the potential beneficial impact of promising natural compounds and dietary supplements on alleviating these significant diseases.

Hirsutism

2011 ◽  
pp. 1239-1249
Author(s):  
Bulent O. Yildiz ◽  
Ricardo Azziz
Keyword(s):  
Hair Growth ◽  
Negative Impact ◽  
Polycystic Ovary ◽  
Clinical Investigation ◽  
Androgen Excess ◽  
Clinical Diagnostic Criterion ◽  
Significant Negative Impact ◽  
Race Ethnicity ◽  
Diagnostic Criterion

Hirsutism is defined as excess growth of body or facial terminal (coarse) hair in females, in a male-like pattern. The condition has a significant negative impact on a woman’s self-esteem and on her quality of life. Hirsutism affects 5–15% of the women, and is the most commonly used clinical diagnostic criterion of androgen excess or hyperandrogenism (1). Depending on age and race/ethnicity, 80–90% of women with hirsutism will have an androgen excess disorder, most often polycystic ovary syndrome (PCOS), and including idiopathic hirsutism, and non-classic congenital adrenal hyperplasia (NCAH), among the others. This chapter outlines androgen metabolism in women, physiology and pathophysiology of hair growth, epidemiology of and differential diagnosis of hirsutism, other signs of androgen excess including acne, androgenetic alopecia, and virilization, and the clinical investigation, and treatment of the hirsute patient.

Psychosocial approach of polycystic ovary syndrome

2014 ◽  
Vol 155 (47) ◽  
pp. 1867-1871
Author(s):  
Ildikó Kohlné Papp
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Metabolic Disorders ◽  
Psychological Symptoms ◽  
Negative Impact ◽  
Polycystic Ovary ◽  
Reproductive Age ◽  
Ovary Syndrome ◽  
Endocrine Disease ◽  
Psychiatric Problems

Polycystic ovary syndrome is the most frequent endocrine disease among women of reproductive age. It is associated with increased risks of various metabolic disorders and complications. most recent data suggest that women suffering from polycystic ovary syndrome are most exposed to several psychological problems. It has been shown that polycystic ovary syndrome exerts a negative impact on female identity and it contributes to the deterioration of quality of life and, eventually, to development of psychiatric problems. The mental consequences of the disease can be as depressing as physiological symptoms. This draws attention on the importance of the disease from the aspect of therapy as well and, therefore, it may be justified to involve a psychologist or psychiatrist in the process for a more effective treatment. The aim of the paper is to summarize the most frequqent psychological symptoms associated with the disease. Orv. Hetil., 2014, 155(47), 1867–1871.

scholarly journals Women's reproductive health and features of eating behavior

2019 ◽  
Vol 4 (3) ◽  
pp. 48-53
Author(s):  
S. I. Yelgina ◽  
I. S. Zakharov ◽  
E. V. Rudaeva
Keyword(s):  
Breast Cancer ◽  
Eating Disorders ◽  
Food Intake ◽  
Polycystic Ovary ◽  
Uterine Fibroids ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Ovary Syndrome ◽  
External Eating ◽  
Gynecological Diseases

Aim. To study reproductive health of women with and without eating disorders.Materials and Methods. We designed an original questionnaire, surveyed and analyzed the medical records of 200 women of reproductive age.Results. All the study participants suffered from eating disorders. Out of 200 patients, 46 (23%), 120 (63%), and 34 (17%) had emotional, restrictive, and external eating disorders, respectively. Women with normal body mass index (BMI) or overweight were more likely to have an avoidant/restrictive food intake disorder while emotional and external types prevailed among obese patients. Fibrocystic breast changes, uterine fibroids, polycystic ovary syndrome, infertility, and breast cancer were significantly more common in women with obesity (r = 0.74 for gynecological diseases in total). Pelvic inflammatory disease was more frequently diagnosed in women with emotional eating disorders while fibrocystic breast changes, uterine fibroids, and polycystic ovary syndrome were more prevalent in those with restrictive food intake disorder. Breast cancer prevailed in women with external eating disorders.Conclusion. Women of reproductive age are frequently diagnosed with different types of eating disorders. Obese women are more likely to have reproductive system disease. Each of eating disorders correlate with different gynecological diseases. 

scholarly journals Fibroids and Infertility

2021 ◽  
Author(s):  
Juan Luis Giraldo Moreno ◽  
Susana Salazar López
Keyword(s):  
Negative Impact ◽  
Embryo Implantation ◽  
Uterine Fibroids ◽  
Abnormal Uterine Bleeding ◽  
Open Approach ◽  
Pelvic Tumors ◽  
Increased Risk ◽  
Submucosal Fibroids ◽  
Intramural Fibroids

Uterine fibroids (also known as leiomyomas or myomas) are the most common pelvic tumors, affecting more than 70% of women over 70 years of age and although most are asymptomatic, some women may experience symptoms, depending on their location and size, which can alter your quality of life, such as abnormal uterine bleeding, anemia, pelvic pain and pressure, dyspareunia, increased urinary frequency and constipation. Its relationship with infertility has been controversial and, although insignificant for subserous fibroids, it appears that submucosal and intramural fibroids that distort the endometrial cavity can affect embryo implantation and are associated with an increased risk of early pregnancy loss. Its treatment will depend on the patient’s symptoms, size, location, whether it is one or multiple, and whether or not she suffers from infertility. It is clear that submucosal fibroids have a negative impact on fertility and with respect to intramural fibroids it is known that fibroids larger than 4 cm alter the probability of pregnancy, however there are studies that show that even smaller or multiple fibroids could affect pregnancy rates. There are multiple options for the treatment of fibroids; however, patients who are candidates for expectant, medical or surgical management should be individualized, and especially if they are going to be taken to surgery, an excellent mapping of fibroids prior to surgical intervention is recommended. Minimally invasive surgery continues to be the approach of choice, it should be left for the open approach in cases in which Laparoscopy is contraindicated or the patient with multiple myomatosis.

scholarly journals Neurotoxicity Associated with Cancer Treatment

2017 ◽  
pp. 1-3
Author(s):  
Ghazaleh Shoja Razavi
Keyword(s):  
Adverse Events ◽  
Therapeutic Approach ◽  
Negative Impact ◽  
Malignant Tumors ◽  
Hematologic Malignancies ◽  
Medical Problems ◽  
Palliative Approach ◽  
Multiple Treatment ◽  
Chemotherapy Protocol

Cancer is one of the prevalent medical problems among people especially in more developed and industrialized population. Now a day, it is considered as the third leading cause of death following cardiovascular problems and accidents. Moreover, the therapeutic approach to malignant tumors has been developed significantly compared with 70s and 80s. Many immunotherapies and targeted therapies have been developed and approved for both solid tumors and hematologic malignancies. Curable approach has been available for many deadly malignancies and multiple treatment lines have been proposed and validated based on the clinical trials in the majority of cancers. Innovative technologies such as nanotechnology have been proposed and developed to optimize the bioavailability of the therapeutic agents within the tumor. However, adverse events associated with these novel therapeutic approaches have been inevitable. Many of these adverse events present acutely during or shortly after the completion of the chemotherapy and resolve spontaneously or with short term palliative approach or even reducing the dose and schedule of the chemotherapy protocol. Few adverse events however, might last for longer periods of time and even life long and show a significantly negative impact on the patients’ quality of life despite the application of palliative approach. Although availability of multiple combination chemotherapy protocols and variety in the type of therapeutic approach might play a role in reducing these adverse events, it is not able to completely eliminate these unwanted effects. Besides, relapsing nature of cancers that necessitates multiple lines of treatment lead to additive and sometimes synergic adverse events that might further debilitate the patients.

scholarly journals Polycystic ovary syndrome and mental disorders – discussion on the recommendations of the European Society of Human Reproduction and Embryology (ESHRE)

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Magdalena Derewianka-Polak ◽  
Grzegorz Polak ◽  
Joanna Tkaczuk-Włach ◽  
Aneta Gerhant ◽  
Marcin Olajossy
Keyword(s):  
Quality Of Life ◽  
Mental Disorders ◽  
Polycystic Ovary Syndrome ◽  
European Society ◽  
Negative Impact ◽  
Polycystic Ovary ◽  
Reproductive Age ◽  
Human Reproduction ◽  
Ovary Syndrome

Abstract Introduction: Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women at the reproductive age. In 2018, the European Society of Human Reproduction and Embryology (ESHRE) developed and published new accurate recommendations for the diagnosis and management of women with PCOS. In this work, a separate chapter is devoted to the quality of life and mental disorders in patients with polycystic ovary syndrome. Material and Methods: This article provides an overview of the literature regarding mental disorders associated with PCOS with the focus on the ESHRE recommendations. Conclusion: The medical staff and patients should be aware of the negative impact of polycystic ovary syndrome on the quality of life, coexistence of depression, anxiety, psychosexual and eating disorders.

scholarly journals Epigenetic background of the most common non-oncologic gynecological diseases

2014 ◽  
Vol 155 (13) ◽  
pp. 492-499
Author(s):  
József Gábor Joó ◽  
Éva Csatlós ◽  
Réka Brubel ◽  
Attila Bokor ◽  
Csaba Karabélyos ◽  
...  
Keyword(s):  
Polycystic Ovary ◽  
Uterine Fibroids ◽  
Epigenetic Mechanisms ◽  
Epigenetic Factors ◽  
Physiological Mechanisms ◽  
Ovary Syndrome ◽  
Pregnancy Care ◽  
Epigenetic Effects ◽  
Gynecological Diseases ◽  
Heritable Phenotype

Epigenetic effects influence the function of genes regulating the main physiological mechanisms. Some of these environmental factors may reduce or inhibit the function of these genes. The environmental effects on gene function may result in a change of the DNA structure leading to non-heritable phenotype changes. Epigenetic factors play an important etiological role in the development of numerous diseases in obstetrics and gynecology. Uterine fibroids probably have a complex etiological background including epigenetic mechanisms. The multifactorial aetiology of endometriosis suggests key roles for immunological and hormonal factors in the development of the diseases. These mechanisms are influenced by epigenetic factors, which may serve as therapeutic targets in the future. The possible in utero origin of polycystic ovary syndrome determines the main directions of research concerning epigenetic factors in the etiological background, with the hope of eventual prevention and/or treatment in the preconceptional period as well as during pregnancy care. Orv. Hetil., 2014, 155(13), 492–499.

Green Beans Cultivation Using Mice Pets Control to Improve the Quality of Bintaro Fruit Extract

2018 ◽  
Vol 1 (1) ◽  
pp. 38
Author(s):  
Ajeng Embri Legawati ◽  
Nur Azizah ◽  
Achmad Ramadhan
Keyword(s):  
Natural Resources ◽  
Negative Impact ◽  
Green Beans ◽  
Fruit Extract ◽  
Bean Plants ◽  
Cultivation Technology ◽  
Environmental Balance ◽  
The Impact ◽  
Chemical Pesticides

Green beans cultivation technology using mice pets control has been implemented in the Gluranploso village, Benjeng Gresik. The implementation of the technology performed for 2.5 months from August to October 2017. The purpose of the implementation is aimed to reduce the dependence of farmers on the use of chemical pesticides so that the farmers are aware of the negative impact of chemical pesticides. Assessing the impact of the utilization of Bintaro fruit and fruit extracts to explore ways of making Bintaro as a natural biopesticide to overcome rat attack on green bean plants in the Gluranploso village. Pest control mice can reduce the rate of loss of the crops more effectively and efficiently. Finally, with the use of those natural resources as a biopesticide material can also maintain the environmental balance

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