scholarly journals Association of Dietary Vitamin D Intake, Serum 25(OH)D3, 25(OH)D2 with Cognitive Performance in the Elderly

Nutrients ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 3089
Author(s):  
RuTong Wang ◽  
Weijing Wang ◽  
Ping Hu ◽  
Ronghui Zhang ◽  
Xue Dong ◽  
...  
Keyword(s):  
Vitamin D ◽  
Cognitive Performance ◽  
Binary Logistic Regression ◽  
The Elderly ◽  
Dietary Vitamin ◽  
Digit Symbol Substitution Test ◽  
Binary Logistic Regression Model ◽  
Older Americans ◽  
Dietary Vitamin D ◽  
Fluency Test

Background: As life expectancy increases, cognitive performance decline in the elderly has become one of the major global challenges. We aimed to evaluate the association of dietary vitamin D (VD), serum 25-hydroxyvitamin D3 (25(OH)D3), 25-hydroxyvitamin D2 (25(OH)D2), and total 25-hydroxyvitamin (25(OH)D) concentration with cognitive performance in older Americans. Methods: The data from the National Health and Nutrition Examination Survey (NHANES), 2011–2014 was used. The cognitive performance was assessed by the Consortium to Establish a Registry for Alzheimer’s Disease (CERAD) Word Learning sub-test, Animal Fluency test, and Digit Symbol Substitution Test (DSST). A binary logistic regression model was applied to evaluate the association between VD and cognitive performance, and restricted cubic spline model was adopted to evaluate the dose–response relationship. Results: While comparing to the lowest dietary VD intake group, the multivariate adjusted odds ratios (ORs) and 95% confidence intervals (CIs) of the highest dietary VD intake group were 0.51 (0.36–0.72) for the Animal Fluency test score and 0.45 (0.31–0.66) for DSST score, respectively; and those of serum total 25(OH)D and 25(OH)D3 concentration were 0.68 (0.47–0.97) and 0.62 (0.44–0.86) for DSST score. L-shaped relationships were identified for dietary VD intake, serum total 25(OH)D and 25(OH)D3 concentration with cognition performance. The associations between dietary VD intake, serum total 25(OH)D and cognitive performance were non-significant when stratified by gender. Conclusions: The study indicates that dietary VD intake, serum total 25(OH)D and 25(OH)D3 concentration were positively associated with cognitive performance. Further studies are needed to clarify the possible effects of dietary VD intake and serum 25(OH)D2, 25(OH)D3 on cognitive performance.

scholarly journals Vitamin D Intake in Slovenian Adolescents, Adults, and the Elderly Population

Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3528
Author(s):  
Maša Hribar ◽  
Hristo Hristov ◽  
Živa Lavriša ◽  
Barbara Koroušić Seljak ◽  
Matej Gregorič ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
The Elderly ◽  
Dietary Vitamin ◽  
Food Groups ◽  
Cross Sectional ◽  
Vitamin D Intake ◽  
Study Results ◽  
Using Data ◽  
Dietary Vitamin D

Vitamin D is involved in calcium and phosphorus metabolism, and is vital for numerous bodily functions. In the absence of sufficient UV-B light-induced skin biosynthesis, dietary intake becomes the most important source of vitamin D. In the absence of biosynthesis, the recommended dietary vitamin D intake is 10–20 µg/day. Major contributors to dietary vitamin D intake are the few foods naturally containing vitamin D (i.e., fish), enriched foods, and supplements. The present study aimed to estimate the vitamin D intake in Slovenia, to identify food groups that notably contribute to vitamin D intake, and to predict the effects of hypothetical mandatory milk fortification. This study was conducted using data collected by the national cross-sectional food consumption survey (SI.Menu) in adolescents (n = 468; 10–17 years), adults (n = 364; 18–64 years), and the elderly (n = 416; 65–74 years). Data collection was carried out between March 2017 and April 2018 using the EU Menu Methodology, which included two 24-hour recalls, and a food propensity questionnaire. Very low vitamin D intakes were found; many did not even meet the threshold for very low vitamin D intake (2.5 µg/day). Mean daily vitamin D intake was 2.7, 2.9, and 2.5 µg in adolescents, adults, and the elderly, respectively. Daily energy intake was found to be a significant predictor of vitamin D intake in all population groups. In adolescents and adults, sex was also found to be a significant predictor, with higher vitamin D intake in males. The study results explained the previously reported high prevalence of vitamin D deficiency in Slovenia. An efficient policy approach is required to address the risk of vitamin D deficiency, particularly in vulnerable populations.

DIETARY VITAMIN D

The Lancet ◽  
1979 ◽  
Vol 314 (8150) ◽  
pp. 1021 ◽  
Author(s):  
D.E.M Lawson
Keyword(s):  
Vitamin D ◽  
Dietary Vitamin ◽  
Dietary Vitamin D

scholarly journals Dietary Vitamin D and Its Metabolites Non-Genomically Stabilize the Endothelium

PLoS ONE ◽  
2015 ◽  
Vol 10 (10) ◽  
pp. e0140370 ◽  
Author(s):  
Christopher C. Gibson ◽  
Chadwick T. Davis ◽  
Weiquan Zhu ◽  
Jay A. Bowman-Kirigin ◽  
Ashley E. Walker ◽  
...  
Keyword(s):  
Vitamin D ◽  
Dietary Vitamin ◽  
Dietary Vitamin D

Association of vitamin D with incident glaucoma: findings from the Women’s Health Initiative

2021 ◽  
pp. jim-2020-001645
Author(s):  
Laura D Carbone ◽  
Karen Johnson ◽  
Joseph C Larson ◽  
Fridtjof Thomas ◽  
Jean Wactawski-Wende ◽  
...  
Keyword(s):  
Vitamin D ◽  
Women's Health ◽  
Postmenopausal Women ◽  
Serum Levels ◽  
Dietary Vitamin ◽  
Health Initiative ◽  
Vitamin D Intake ◽  
Vitamin D Supplements ◽  
Dietary Vitamin D ◽  
The Women’S Health Initiative

The relationship between vitamin D and glaucoma is controversial. The objective of this study was to examine women from the Women’s Health Initiative (WHI) to determine if there is an association between vitamin D and incident glaucoma in postmenopausal women. We examined the association between dietary vitamin D intake, vitamin D supplements and serum 25 hydroxyvitamin D (25(OH)D) levels and the risk of developing glaucoma. 143,389 postmenopausal women from the WHI including a subset with serum 25(OH) D measurements were examined to determine the association of dietary, supplemental and serum levels of vitamin D to the development of glaucoma. Dietary intakes of vitamin D, use of vitamin D supplements and serum levels of 25(OH) D were predictors examined for the main outcome of incident glaucoma. In multivariable models adjusted for demographic, clinical variables and medication use, dietary vitamin D, vitamin D supplements, total vitamin D intake (diet plus supplements) and serum 25 (OH) D measurements were not significantly associated with incident glaucoma. In the CaD placebo-controlled intervention clinical trial, there was also no association in the active intervention arm with glaucoma. We conclude that dietary vitamin D intake, supplements and serum levels are not significantly related to the risk of developing glaucoma in postmenopausal women.

Dietary vitamin D: growth, physiological and health consequences in broiler production

2021 ◽  
pp. 1-7
Author(s):  
Rifat Ullah Khan ◽  
Shabana Naz ◽  
Hammad Ullah ◽  
Nazir Ahmad Khan ◽  
Vito Laudadio ◽  
...  
Keyword(s):  
Vitamin D ◽  
Dietary Vitamin ◽  
Health Consequences ◽  
Broiler Production ◽  
Dietary Vitamin D

RISK FACTORS OF ADVERSE CLINICAL OUTCOMES IN THE ELDERLY AND SENILE PATIENTS WITH STROKE-ASSOCIATED PNEUMONIA

2021 ◽  
pp. 586-591
Author(s):  
В.А. Белобородов ◽  
И.А. Степанов ◽  
А.В. Щербатых ◽  
И.И. Томашов ◽  
З.С. Саакян ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clinical Outcomes ◽  
Nosocomial Pneumonia ◽  
Binary Logistic Regression ◽  
The Elderly ◽  
Older Age ◽  
Binary Logistic Regression Model ◽  
Protein Levels ◽  
Reactive Protein ◽  
Degree Of Disability

В отечественной и зарубежной специализированной литературе отсутствуют исследования, посвященные изучению факторов риска развития неблагоприятного исхода у пациентов старшей возрастной группы с инсультассоциированной нозокомиальной пневмонией. Цель исследования - изучение факторов риска развития неблагоприятного клинического исхода у пациентов пожилого и старческого возраста с нозокомиальной пневмонией на фоне ОНМК. В исследование были включены 247 пациентов пожилого и старческого возраста (139 мужчин, 108 женщин, средний возраст - 74,1±6,3 года), госпитализированных с признаками ОНМК по ишемическому или геморрагическому типу. Согласно модели бинарной логистической регрессии, статистически значимо ассоциированы с развитием неблагоприятного исхода у изучаемой группы респондентов следующие параметры: возраст свыше 75 лет (p=0,011), степень инвалидизации по шкале mRS 3 (р=0,009), а также уровень С-РБ >100 мг/л (р=0,023) и мочевины >7 ммоль/л (р=0,044). Для снижения частоты встречаемости неблагоприятного клинического исхода у пациентов старшей возрастной группы с инсульт-ассоциированной нозокомиальной пневмонией необходимо верифицировать перечисленные выше клинико-лабораторные параметры на ранних этапах госпитализации. In the domestic and foreign specialized literature, there are no studies devoted to the study of risk factors of mortality in the older age patients with stroke-associated nosocomial pneumonia. The purpose of the study was to study the risk factors of adverse clinical outcomes in elderly and senile patients with stroke-associated nosocomial pneumonia. The study included 247 elderly and senile patients (139 men, 108 women, mean age - 74,1±6,3 years) who were hospitalized with signs of ischemic or hemorrhagic stroke. According to the binary logistic regression model, the following parameters are statistically significantly associated with adverse clinical outcomes in the studied group of respondents: age over 75 years (p=0.011), degree of disability according to mRS ≥3 (p=0,009), and C-reactive protein levels over 100 mg/l (p=0,023) and urea more than 7 mmol/l (p=0,044). In order to reduce the incidence of adverse clinical outcomes in patients of the older age group with stroke-associated nosocomial pneumonia, it is necessary to verify the above clinical and laboratory parameters at the early stages of hospitalization.

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