scholarly journals Dietary Fibre Intake in Relation to Asthma, Rhinitis and Lung Function Impairment—A Systematic Review of Observational Studies

Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3594
Author(s):  
Emmanouela Sdona ◽  
Athina Vasiliki Georgakou ◽  
Sandra Ekström ◽  
Anna Bergström

A high intake of dietary fibre has been associated with a reduced risk of several chronic diseases. This study aimed to review the current evidence on dietary fibre in relation to asthma, rhinitis and lung function impairment. Electronic databases were searched in June 2021 for studies on the association between dietary fibre and asthma, rhinitis, chronic obstructive pulmonary disease (COPD) and lung function. Observational studies with cross-sectional, case–control or prospective designs were included. Studies on animals, case studies and intervention studies were excluded. The quality of the evidence from individual studies was evaluated using the RoB-NObs tool. The World Cancer Research Fund criteria were used to grade the strength of the evidence. Twenty studies were included in this systematic review, of which ten were cohort studies, eight cross-sectional and two case–control studies. Fibre intake during pregnancy or childhood was examined in three studies, while seventeen studies examined the intake during adulthood. There was probable evidence for an inverse association between dietary fibre and COPD and suggestive evidence for a positive association with lung function. However, the evidence regarding asthma and rhinitis was limited and inconsistent. Further research is needed on dietary fibre intake and asthma, rhinitis and lung function among adults and children.

2017 ◽  
Vol 71 (10) ◽  
pp. 961-969 ◽  
Author(s):  
Eileen Shaw ◽  
Matthew T Warkentin ◽  
S Elizabeth McGregor ◽  
Susanna Town ◽  
Robert J Hilsden ◽  
...  

BackgroundThere is suggestive evidence that increased intake of dietary fibre and the use of non-steroidal anti-inflammatory drugs (NSAIDs) are generally associated with decreased colorectal cancer risk. However, the effects on precursors of colorectal cancer, such as adenomatous polyps, are mixed. We present the associations between dietary fibre intake and NSAID use on the presence and type of colorectal polyps in a screening population.MethodsA cross-sectional study of 2548 individuals undergoing colonoscopy at the Forzani & MacPhail Colon Cancer Screening Centre (Calgary, Canada) was conducted. Dietary fibre intake and NSAID use were assessed using the Diet History Questionnaire I or II and the Health and Lifestyle Questionnaire. Colorectal outcomes were documented as a polyp or high-risk adenomatous polyp (HRAP; villous histology, high-grade dysplasia, ≥10 mm or ≥3 adenomas). Crude and ORs and 95% CIs were estimated using unconditional logistic regression.ResultsThere were 1450 negative colonoscopies and 1098 patients with polyps, of which 189 patients had HRAPs. Total dietary fibre intake was associated with a decreased presence of HRAPs (OR=0.50, 95% CI: 0.29 to 0.86) when comparing the highest to lowest quartiles and was observed with both soluble (OR=0.51, 95% CI: 0.30 to 0.88) and insoluble (OR=0.51, 95% CI: 0.30 to 0.86) fibres. Ever use of NSAIDs was also inversely associated with HRAPs (OR=0.65, 95% CI: 0.47 to 0.89), observed with monthly (OR=0.60, 95% CI: 0.37 to 0.95) and daily (OR=0.53, 95% CI: 0.32 to 0.86) use.ConclusionsDietary fibre intake and NSAID use were associated with a decreased risk of having a HRAP at screening.


2019 ◽  
Vol 11 (2) ◽  
pp. 141
Author(s):  
Imfatul Tria Nur Azizah

Organic fertilizer industry in Nganjuk uses manure as basic materials of production. Its process produced particulate matter 2,5 (PM2,5) in the form of dust and smoke. PM2,5 can be inhaled and be retained until alveoli, so it is potentially caused lung function impairment to the workers. The objective of this research was to analyzed the level of PM2,5 and lung function of organic fertilizer industry workers in Nganjuk. The type of this research was observasional descriptive quantitative with cross sectional design. The research sample was using total population of 10 production workers. The result of this research showed that the level of PM2,5 inhaled which exceeded Threshold Limit Value (TLV) or > 3 mg/m3 were on 2 workers who worked on drying and packing process. The average of PM2,5  environment level which exceeded TLV were on manufacturing of granuls, heating and packing process area. Workers who had lung function impairment were 4 workers (40%). Lung function impairment more likely found in workers with exposure of PM2,5 inhaled≤ 3 mg/m3, has age 41 – 60 years, worked period < 5 years, always using cloth as respiratory protective equipment, and had worked in the other places either direct or indirect exposure of dust. The conclusion of this research is production workers of organic fertilizer industry in Nganjuk has risk of lung function impairment. Suggestions for the owner of organic fertilizer industry in Nganjuk are to install natural and unnatural ventilations and to provide air purifying respirators.


PLoS ONE ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. e95099 ◽  
Author(s):  
Allison A. Lambert ◽  
Gregory D. Kirk ◽  
Jacquie Astemborski ◽  
Enid R. Neptune ◽  
Shruti H. Mehta ◽  
...  

2012 ◽  
Vol 71 (OCE3) ◽  
Author(s):  
D. E. Threapleton ◽  
D. C. Greenwood ◽  
C. E. Evans ◽  
C. L. Cleghorn ◽  
C. Nykjaer ◽  
...  

Nutrients ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 1579 ◽  
Author(s):  
Vincenza Gianfredi ◽  
Daniele Nucci ◽  
Tania Salvatori ◽  
Giulia Dallagiacoma ◽  
Cristina Fatigoni ◽  
...  

The aim of this systematic review and meta-analysis was to evaluate the association between dietary fibre intake and rectal cancer (RC) risk. In January 2019, a structured computer search on PubMed/Medline, Excerpta Medica dataBASE (EMBASE) and Scopus was performed for studies reporting the results of primary research evaluating dietary fibre intake in women and men as well as the risk of developing RC. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations were followed. Highest vs. lowest fibre concentrations was compared. The Egger test was used to estimate publication bias. Heterogeneity between studies was evaluated with I2 statistics. The search strategy identified 912 papers, 22 of which were included in our meta-analysis. Having evaluated a total of 2,876,136 subjects, the results suggest a protective effect of dietary fibre intake on RC prevention. The effect Size (ES) was [0.77 (95% CI = 0.66–0.89), p-value = 0.001)]. Moderate statistical heterogeneity (Chi2 = 51.36, df = 21, I2 = 59.11%, p-value = 0.000) was found. However, no publication bias was found, as confirmed by Egger’s linear regression test (Intercept −0.21, t = −0.24, p = 0.816). The findings suggest that dietary fibre intake could be protective against RC, with a clinically relevant reduction of RC risk. Identifying preventive measures to avoid the development of RC, especially by following a healthy lifestyle including healthy diet, is pivotal.


2012 ◽  
Vol 71 (OCE3) ◽  
Author(s):  
D. E. Threapleton ◽  
D. C. Greenwood ◽  
C. Evans ◽  
C. L. Cleghorn ◽  
C. Nykjaer ◽  
...  

BMJ Open ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. e030094
Author(s):  
Jessica Lang ◽  
Michael K Felten ◽  
Thomas Kraus

ObjectivesThe knowledge of past asbestos exposure may lead to chronic psychological strain. In addition, the information about an increased cancer risk can place a psychological burden on individuals triggering mental health symptoms of depression or anxiety. This applies in particular to individuals with non-malignant asbestos-related disease (ARD) such as lung fibrosis and pleural thickening with or without lung function impairment. ARDs with or without lung function impairment may develop even years after exposure cessation. Therefore, the aim of the present study was to test for our cohort whether non-malignant ARD and lung function impairment have differential effects on mental health and psychological strain.DesignCross-sectional study.Participants and settingOverall, 612 male participants (mean age=66.2 years, SD=9.5) attending a surveillance programme for ARDs received routine examinations including lung function testing (24% refused to fill in the psychological questionnaire) at a German university hospital study centre from August 2008 to August 2013.Outcome measuresUsing multiple hierarchical regression analysis, ARD diagnosis and lung function impairment were used to predict psychological health as measured with validated questionnaires for depression and anxiety. Psychological strain was operationalised by intrusive thoughts and specific fear of cancer.ResultsThe strongest predictor for mental health was obstructive functional impairment (eg, anxiety: β=0.22, p<0.001). Psychological strain was predicted by the presence of a non-malignant ARD (eg, intrusive thoughts: β=0.17, p=0.003).ConclusionsThe presence of mental health symptoms is associated with ventilation disturbances, whereas the knowledge of an already initiated morphological change—caused by asbestos exposure—is primarily associated with psychological strain. Specifically, the affected individuals are more prone to intrusive thoughts and specific fear of asbestos-related cancer. As an implication, physicians should be sensitised about possible consequences of risk communication and functional impairment to counteract excessive fear or anxiety.


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