scholarly journals Core/Sheath-Structured Composite Nanofibers Containing Cinnamon Oil: Their Antibacterial and Antifungal Properties and Acaricidal Effect against House Dust Mites

Polymers ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 243 ◽  
Author(s):  
Yoonwon Jung ◽  
Hyukjoo Yang ◽  
In-Yong Lee ◽  
Tai-Soon Yong ◽  
Seungsin Lee

This study aimed to fabricate core/sheath-structured composite nanofibers containing cinnamon oil by emulsion electrospinning and to investigate their acaricidal effect on house dust mites as well as their antibacterial and antifungal properties in relation to cinnamon oil concentration in the nanofibers. An oil-in-water emulsion, which comprised cinnamon oil and poly(vinyl alcohol) solution as oil and water phases, respectively, was used to prepare core/sheath-structured nanofibers. The morphology and the inner structure of the electrospun nanofibers were observed by scanning electron microscopy and confocal laser scanning microscopy. Core/sheath-structured nanofibers containing cinnamon oil were successfully prepared by emulsion electrospinning. The composite nanofibers prepared from an emulsion containing 20 wt% of cinnamon oil exhibited a strong acaricidal effect against house dust mites (Dermatophagoides farinae). The composite nanofibers fabricated from an emulsion containing 4.29 wt% of cinnamon oil showed excellent antimicrobial effects against Staphylococcus aureus and a series of fungi that can trigger respiratory- and skin-related diseases. The release profile of cinnamon oil from the core/sheath-structured nanofibers showed a continuous release of functional ingredients over 28 days. Our findings demonstrate that the use of such fibrous structures could be a promising approach for delivering naturally derived bioactive agents in a controlled way.




2019 ◽  
Vol 8 (3) ◽  
pp. 511
Author(s):  
Gardenia Akhyar ◽  
Rahma Ledika Veroci

Beberapa kasus urtikaria pada paparan debu dan diantaranya menghubungkan sensitivitas tungau debu rumah (TDR) dengan urtikaria berdasarkan riwayat pasien dan pemeriksaan uji intradermal. Tujuan penelitian ini adalah menentukan korelasi antara kepadatan TDR dan rekurensi urtikaria. Jumlah sampel pada penelitian ini 30 orang. Kepadatan TDR dari tiap kamar sampel dihitung dengan mengumpulkan debu, dan sampel dinilai sensitivitas terhadao TDR dengan pemeriksaan skin prick test (SPT). Diagnosis urtikaria berdasarkan anamnesis, kemudian ditanyaan rekurensinya dalam tiga bulan terakhir. Hasil: Dari 30 peserta, tujuh (23,3%) sampel memiliki kepadatan TDR sedang sementara 23 (76,7%) memiliki kepadatan rendah. Selain itu, 15 sampel positif SPT terhadap alergen TDR. Dari anamnesis, 12 (40%) sampel didiagnosis urtikaria dan diantaranya, 11 orang (91,67%) positif terhadap SPT. Tidak ada sampel yang memiliki rekurensi urtikaria dalam tiga bulan terakhir. Kesimpulan: Meskipun penelitian ini tidak menunjukkan korelasi yang signifikan antara kepadatan TDR dan tingkat kekambuhan urtikaria (p> 0,05), TDR memang bisa memicu eksaserbasi. Penelitian ini membutuhkan penyelidikan lebih lanjut dengan ukuran sampel yang lebih besar.



Coatings ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 464
Author(s):  
Simona Liliana Iconaru ◽  
Mihai Valentin Predoi ◽  
Patrick Chapon ◽  
Sofia Gaiaschi ◽  
Krzysztof Rokosz ◽  
...  

In this study, the cerium-doped hydroxyapatite (Ca10−xCex(PO4)6(OH)2 with xCe = 0.1, 10Ce-HAp) coatings obtained by the spin coating method were presented for the first time. The stability of the 10Ce-HAp suspension particles used in the preparation of coatings was evaluated by ultrasonic studies, transmission electron microscopy (TEM), X-ray diffraction (XRD), and scanning electron microscopy (SEM). The surface morphology of the 10Ce-HAp coating was studied by SEM and atomic force microscopy (AFM) techniques. The obtained 10Ce-HAp coatings were uniform and without cracks or unevenness. Glow discharge optical emission spectroscopy (GDOES) and X-ray photoelectron spectroscopy (XPS) were used for the investigation of fine chemical depth profiling. The antifungal properties of the HAp and 10Ce-HAp suspensions and coatings were assessed using Candida albicans ATCC 10231 (C. albicans) fungal strain. The quantitative antifungal assays demonstrated that both 10Ce-HAp suspensions and coatings exhibited strong antifungal properties and that they successfully inhibited the development and adherence of C. albicans fungal cells for all the tested time intervals. The scanning electron microscopy (SEM) and confocal laser scanning microscopy (CLSM) visualization of the C. albicans fungal cells adherence to the 10Ce-HAp surface also demonstrated their strong inhibitory effects. In addition, the qualitative assays also suggested that the 10Ce-HAp coatings successfully stopped the biofilm formation.



Author(s):  
Ana Sofia Oliveira ◽  
Carlos Gaspar ◽  
Joana Rolo ◽  
Cristiana Costa Pereira ◽  
Rita Palmeira-de-Oliveira ◽  
...  


2001 ◽  
Vol 52 (2) ◽  
pp. 149 ◽  
Author(s):  
T. Hashimoto ◽  
K. Mizutani ◽  
G. Shinjo


1998 ◽  
Vol 35 (1) ◽  
pp. 46-53 ◽  
Author(s):  
Larry G. Arlian ◽  
Patricia D. Confer ◽  
Christine M. Rapp ◽  
Diann L. Vyszenski-Moher ◽  
John C. S. Chang


2005 ◽  
Vol 95 (1) ◽  
pp. 38-44 ◽  
Author(s):  
Giorgio Ciprandi ◽  
Daniela Fenoglio ◽  
Ignazio Cirillo ◽  
Andrea Vizzaccaro ◽  
Alessandra Ferrera ◽  
...  


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