scholarly journals Iodine Immobilized UiO-66-NH2 Metal-Organic Framework as an Effective Antibacterial Additive for Poly(ε-caprolactone)

Polymers ◽  
2022 ◽  
Vol 14 (2) ◽  
pp. 283
Author(s):  
Wei Chen ◽  
Ping Zhu ◽  
Yating Chen ◽  
Yage Liu ◽  
Liping Du ◽  
...  

Iodine has been widely used as an effective disinfectant with broad-spectrum antimicrobial potency. However, the application of iodine in an antibacterial polymer remains challenging due to its volatile nature and poor solubility. Herein, iodine immobilized UiO-66-NH2 metal-organic framework (MOF) (UiO66@I2) with a high loading capacity was synthesized and used as an effective antibacterial additive for poly(ε-caprolactone) (PCL). An orthogonal design approach was used to achieve the optimal experiments’ conditions in iodine adsorption. UiO66@I2 nanoparticles were added to the PCL matrix under ultrasonic vibration and evaporated the solvent to get a polymer membrane. The composites were characterized by SEM, XRD, FTIR, and static contact angle analysis. UiO-66-NH2 nanoparticles have a high iodine loading capacity, up to 18 wt.%. The concentration of iodine is the most important factor in iodine adsorption. Adding 0.5 wt.% or 1.0 wt.% (equivalent iodine content) of UiO66@I2 to the PCL matrix had no influence on the structure of PCL but reduces the static water angle. The PCL composites showed strong antibacterial activities against Staphylococcus aureus and Escherichia coli. In contrast, the same content of free iodine/PCL composites had no antibacterial activity. The difference in the antibacterial performance was due to the different iodine contents in the polymer composites. It was found that MOF nanoparticles could retain most of the iodine during the sample preparation and storage, while there was few iodine left in the free iodine/PCL composites. This study offers a common and simple way to immobilize iodine and prepare antibacterial polymers with low antiseptic content that would reduce the influence of an additive on polymers’ physical properties.

2019 ◽  
Vol 10 (18) ◽  
pp. 2263-2272 ◽  
Author(s):  
Huaizhi Liu ◽  
Hao Peng ◽  
Yumeng Xin ◽  
Jiuyang Zhang

We reported for the first time using metal–organic framework (MOF) nanoparticles as effective nanofillers to significantly enhance the mechanical performance of hydrogels. The MOF hydrogels have been developed for drug delivery materials with high loading capacity and much extended drug releasing profiles.


2020 ◽  
Vol 20 (3) ◽  
pp. 1378-1382 ◽  
Author(s):  
Xin Chen ◽  
Xue Jiang ◽  
Xingfeng Lei ◽  
Baoliang Zhang ◽  
Mingtao Qiao ◽  
...  

2021 ◽  
Author(s):  
Zhao Liu ◽  
Junwei Ye ◽  
Abdul Rauf ◽  
Siqi Zhang ◽  
Guangyao Wang ◽  
...  

Flexible antibacterial fibrous membrane employing high antibacterial efficiency has great potential in healthcare applications. Herein, a three-dimensional copper(II) metal-organic framework [Cu2(CA)(H2O)2, Cu-MOF-1] and poly(lactic acid) (PLA) composite fibrous membrane was...


2016 ◽  
Vol 8 (37) ◽  
pp. 24699-24702 ◽  
Author(s):  
Wei Guo ◽  
Meiqin Zha ◽  
Zhengbang Wang ◽  
Engelbert Redel ◽  
Zhengtao Xu ◽  
...  

2019 ◽  
Vol 7 (21) ◽  
pp. 13173-13179 ◽  
Author(s):  
Bingbing Guo ◽  
Fugang Li ◽  
Chiming Wang ◽  
Liangliang Zhang ◽  
Daofeng Sun

We synthesized a rare (3,12)-connected zirconium metal–organic framework with a sky topology showing efficient iodine adsorption and pH sensing capacity.


2019 ◽  
Vol 58 (20) ◽  
pp. 14145-14150 ◽  
Author(s):  
Xinran Zhang ◽  
Ivan da Silva ◽  
Rodrigo Fazzi ◽  
Alena M. Sheveleva ◽  
Xue Han ◽  
...  

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