scholarly journals MicroRNA as a Biomarker for Diagnostic, Prognostic, and Therapeutic Purpose in Urinary Tract Cancer

Processes ◽  
2021 ◽  
Vol 9 (12) ◽  
pp. 2136
Author(s):  
Amro M. Soliman ◽  
Mohamed Soliman ◽  
Srijit Das ◽  
Seong Lin Teoh
Keyword(s):  
Urinary Tract ◽  
Early Diagnosis ◽  
Tumor Suppressor Genes ◽  
Survival Rates ◽  
Urinary System ◽  
Tract Cancer ◽  
Current Review ◽  
Non Coding Rna ◽  
Urinary Tract Cancer ◽  
Urologic Cancers

The incidence of urologic cancers, including kidney, upper tract urothelial, and bladder malignancies, is increasing globally, with a high percentage of cases showing metastasis upon diagnosis and low five-year survival rates. MicroRNA (miRNA), a small non-coding RNA, was found to regulate the expression of oncogenes and tumor suppressor genes in several tumors, including cancers of the urinary system. In the current review, we comprehensively discuss the recently reported up-or down-regulated miRNAs as well as their possible targets and regulated pathways involved in the development, progression, and metastasis of urinary tract cancers. These miRNAs represent potential therapeutic targets and diagnostic/prognostic biomarkers that may help in efficient and early diagnosis in addition to better treatment outcomes.

Present status and technique for early detection of renal cell carcinoma and urinary tract cancer in US screening

Choonpa Igaku ◽  
2010 ◽  
Vol 37 (2) ◽  
pp. 107-114
Author(s):  
Shuichi MIHARA ◽  
Kouji OTAKE ◽  
Hiroyuki KOBA ◽  
Shinji TANAKA ◽  
Shinichi HIRAO
Keyword(s):  
Renal Cell Carcinoma ◽  
Urinary Tract ◽  
Early Detection ◽  
Cell Carcinoma ◽  
Present Status ◽  
Renal Cell ◽  
Tract Cancer ◽  
Urinary Tract Cancer

scholarly journals Associations between interventions for urolithiasis and urinary tract cancer among patients in Taiwan

Medicine ◽  
2016 ◽  
Vol 95 (49) ◽  
pp. e5594 ◽  
Author(s):  
Chien-Liang Lin ◽  
Wen-Tsung Huang ◽  
Wen-Chou Fan ◽  
Yin-Hsun Feng ◽  
Chia-Ho Lin ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Tract Cancer ◽  
Urinary Tract Cancer

Should Patients With Primary Upper Urinary Tract Cancer Receive Prophylactic Intravesical Chemotherapy After Nephroureterectomy?

2010 ◽  
Vol 183 (1) ◽  
pp. 56-61 ◽  
Author(s):  
Wen-Jeng Wu ◽  
Hung-Lung Ke ◽  
Yi-Hsin Yang ◽  
Ching-Chia Li ◽  
Yii-Her Chou ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Upper Urinary Tract ◽  
Intravesical Chemotherapy ◽  
Tract Cancer ◽  
Urinary Tract Cancer ◽  
Upper Urinary Tract Cancer

Surveillance for urinary tract cancer in Lynch syndrome

2013 ◽  
Vol 12 (2) ◽  
pp. 279-284 ◽  
Author(s):  
Inge Thomsen Bernstein ◽  
Torben Myrhøj
Keyword(s):  
Urinary Tract ◽  
Lynch Syndrome ◽  
Tract Cancer ◽  
Urinary Tract Cancer

Impairment of Antipyrine Metabolism in Urinary Tract Cancer

1983 ◽  
Vol 69 (3) ◽  
pp. 221-222 ◽  
Author(s):  
Maura Ludovici ◽  
Piero Dolara ◽  
Alfiero Costantini ◽  
Guido Barbagli ◽  
Anna Calzolai ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Half Life ◽  
Clinical Parameters ◽  
Tract Cancer ◽  
Patients With Cancer ◽  
Control Subjects ◽  
Antipyrine Metabolism ◽  
Urinary Tract Cancer ◽  
The Mean ◽  
Age And Sex

The metabolism of antipyrine was studied in 13 patients with cancer and bladder papillomas and in 11 control subjects, matched for interfering factors like smoking, diet, age and sex. The mean antipyrine half-life was significantly longer in patients with urinary tract cancer (14.7 ± 1.32 h SE) than in control subjects (11 ± 0.55 h SE) (P < 0.025); other clinical parameters did not vary.

scholarly journals Kinetic and thermodynamic Studies Of Alanine Aminopeptidase(AAP) Isoenzymes I,II Partially Purified From Patient's Urine With Urinary Tract Cancer

2014 ◽  
Vol 11 (1) ◽  
pp. 70-80
Author(s):  
Baghdad Science Journal
Keyword(s):  
Urinary Tract ◽  
Arrhenius Equation ◽  
Kinetic Constant ◽  
Gel Filtration ◽  
First Order ◽  
Tract Cancer ◽  
Kinetics Studies ◽  
Urinary Tract Cancer ◽  
Alanine Aminopeptidase ◽  
Kinetic And Thermodynamic Studies

The activity of Alanine aminopeptidase( AAP ) was measured in the urine of healthy and urinary tract cancer patients , the results showed higher activity of (AAP) in patients compared to healthy . AAP was Purified from the urine of healthy and patients with urinary tract cancer by dialysis and gel filtration (Sephadex G – 50) and two isoenzymes of (AAP) were separated from urine by using ion-exchang resin (DEAE – Sephadex A – 50 ) in previous study. The kinetics studies showed that both isoenzymes I and II obeyed Michaelis – Menton equation . with optimal concentration of alanine-4-nitroanilide as substrate for isoenzymes I and II which was (2 x 10-3 mol/L ). The two isoenzymes obeyed Arrhenius equation up two 37° C and their Ea and Q10 constants were determined . The binding of alanine-4-nitroanilide by two isoenzymes I , II were studied and the kinetic constant ( k+1 , k-1 , Ka , Ks ) were indicated that the reaction was first order at 37° C .Thermodynamic parameters of the standard state ( ?G°, ?H° , ?S° ) and the transition state ( ?G*, ?H* , ?S* ) were determined by using Vant Hoff and Arrhenius equations.

Vindesine in advanced renal cancer. A study of the EORTC genito-urinary tract cancer cooperative group

1983 ◽  
Vol 19 (4) ◽  
pp. 473-475 ◽  
Author(s):  
Sophie D. Fosså ◽  
Louis Denis ◽  
Allan T. Van Oosterom ◽  
Marleen De Pauw ◽  
Gerrit Stoter
Keyword(s):  
Urinary Tract ◽  
Renal Cancer ◽  
Cooperative Group ◽  
Tract Cancer ◽  
Advanced Renal Cancer ◽  
Urinary Tract Cancer
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