scholarly journals Microwave Oscillator Design for a SRR Based Biosensor Platform

Proceedings ◽  
2018 ◽  
Vol 2 (13) ◽  
pp. 865
Author(s):  
Martin Brandl ◽  
Lisa-Marie Wagner

A sensor for biomedical markers based on a split ring microwave resonator (SRR) was developed. The surface of the microwave resonator is covered with receptors that specifically bind to the target proteins where the local permittivity is changed. The resonator is part of a microwave oscillator circuit. Changes in the local permittivity caused by coupling of the target proteins result in a change of oscillator frequency which can be easily and accurate measured with high sensitivity.

Author(s):  
Jeffery P. Huynh ◽  
Joseph P. Shannon ◽  
Richard W. Johnson ◽  
Mike Santana ◽  
Thomas Y. Chu ◽  
...  

Abstract Modifications directly to a transistor’s source/drain and polysilicon gate through the backside of a SOI device were made. Contact resistance data was obtained by creating contacts through the buried oxide layer of a manufactured test structure. A ring oscillator circuit was modified and the shift in oscillator frequency was measured. Finally, cross section images of the FIB created contacts were presented in the paper to illustrate the entire process.


Author(s):  
Divya Prakash ◽  
Nisha Gupta

Abstract Sensors based on metamaterial absorbers are very promising when it comes to high sensitivity and quality factor, cost, and ease of fabrication. The absorbers could be used to sense physical parameters such as temperature, pressure, density as well as they could be used for determining electromagnetic properties of materials and their characterization. In this work, an attempt has been made to explore the various possible applications of these sensors. Metamaterial-based sensors are very popular for its diverse applications in areas such as biomedical, chemical industry, food quality testing, agriculture. Split-ring resonators with various shapes and topologies are the most frequently used structures where the sensing principle is based on electromagnetic interaction of the material under test with the resonator. Overcoming the design challenges using metamaterial sensors involving several constraints such as cost, compactness, reusability, ease in fabrication, and robustness is also addressed.


Sensors ◽  
2021 ◽  
Vol 21 (10) ◽  
pp. 3385
Author(s):  
Jialu Ma ◽  
Jingchao Tang ◽  
Kaicheng Wang ◽  
Lianghao Guo ◽  
Yubin Gong ◽  
...  

A complex permittivity characterization method for liquid samples has been proposed. The measurement is carried out based on a self-designed microwave sensor with a split ring resonator (SRR), the unload resonant frequency of which is 5.05 GHz. The liquid samples in capillary are placed in the resonant zone of the fabricated senor for high sensitivity measurement. The frequency shift of 58.7 MHz is achieved when the capillary is filled with ethanol, corresponding a sensitivity of 97.46 MHz/μL. The complex permittivity of methanol, ethanol, isopropanol (IPA) and deionized water at the resonant frequency are measured and calibrated by the first order Debye model. Then, the complex permittivity of different concentrations of aqueous solutions of these materials are measured by using the calibrated sensor system. The results show that the proposed sensor has high sensitivity and accuracy in measuring the complex permittivity of liquid samples with volumes as small as 0.13 μL. It provides a useful reference for the complex permittivity characterization of small amount of liquid chemical samples. In addition, the characterization of an important biological sample (inositol) is carried out by using the proposed sensor.


2019 ◽  
Vol 5 (2) ◽  
pp. 29
Author(s):  
Kazuo Furihata ◽  
Mitsuru Tashiro

The water ligand observed via a gradient spectroscopy type experiment with 19F detection was applied to selectively detect fluorinated compounds with affinity to the target proteins. The 19F signals of bound and unbound compounds were observed as opposite phases, which was advantageous to distinguish the binding state. The proposed NMR method was optimized based on the 19F{1H} saturation transfer difference pulse sequence, and various inversion pulses for the water resonance were evaluated with the aim of high sensitivity.


Chemosensors ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 328
Author(s):  
Hamid Sadabadi ◽  
Ali Bostani ◽  
Amin S. Esmaeili

The prolonged sensing of toxic gases in polluted particles and harsh environments is a challenging task that is also in high demand. In this work, the proof of principle of a sensitive, low-cost, and low-maintenance reconfigurable platform for filter-free and continuous ammonia (NH3) sensing in polluted environments is simulated. The platform can be modified for the detection of various toxic gases and includes three main modules: a microfluidic system for in-line continuous dust filtering; a toxic gas adsorption module; and a low-frequency microwave split-ring resonator (SRR). An inertia-based spiral microfluidic system has been designed and optimized through simulation for the in-line filtration of small particles from the intake air. Zeolite Y is selected as the adsorbent in the adsorption module. The adsorption module is a non-metallic thin tube that is filled with zeolite Y powder and precisely fixed at the drilled through-hole into the 3D microwave system. For the sensing module, a low-frequency three-dimensional (3D) split-ring resonator is proposed and optimally designed. A microwave resonator continuously monitors the permittivity of zeolite Y and can detect small permittivity alterations upon the presence of ammonia in the intake air. The microwave resonator is optimized at a frequency range of 2.5–3 GHz toward the detection of ammonia under different ammonia concentrations from 400 to 2800 ppm. The microwave simulation results show a clear contrast of around 4 MHz that shifts at 2.7 GHz for 400 ppm ammonia concentration. The results show the proof of principle of the proposed microfluidic-microwave platform for toxic gas detection.


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