scholarly journals Characterization and Monitoring of Titanium Bone Implants with Impedance Spectroscopy

Sensors ◽  
2020 ◽  
Vol 20 (16) ◽  
pp. 4358
Author(s):  
Alberto Olmo ◽  
Miguel Hernández ◽  
Ernesto Chicardi ◽  
Yadir Torres
Keyword(s):  
Impedance Spectroscopy ◽  
Pore Size ◽  
Bone Tissue ◽  
Electrical Impedance ◽  
Porous Titanium ◽  
Electrical Impedance Spectroscopy ◽  
Bone Implants ◽  
Non Invasive ◽  
Metallic Biomaterial ◽  
Porosity Percentage

Porous titanium is a metallic biomaterial with good properties for the clinical repair of cortical bone tissue, although the presence of pores can compromise its mechanical behavior and clinical use. It is therefore necessary to characterize the implant pore size and distribution in a suitable way. In this work, we explore the new use of electrical impedance spectroscopy for the characterization and monitoring of titanium bone implants. Electrical impedance spectroscopy has been used as a non-invasive route to characterize the volumetric porosity percentage (30%, 40%, 50% and 60%) and the range of pore size (100–200 and 355–500 mm) of porous titanium samples obtained with the space-holder technique. Impedance spectroscopy is proved to be an appropriate technique to characterize the level of porosity of the titanium samples and pore size, in an affordable and non-invasive way. The technique could also be used in smart implants to detect changes in the service life of the material, such as the appearance of fractures, the adhesion of osteoblasts and bacteria, or the formation of bone tissue.

Non-invasive assessment of radiation injury with electrical impedance spectroscopy

2004 ◽  
Vol 49 (5) ◽  
pp. 665-683 ◽  
Author(s):  
K Sunshine Osterman ◽  
P Jack Hoopes ◽  
Christine DeLorenzo ◽  
David J Gladstone ◽  
Keith D Paulsen
Keyword(s):  
Impedance Spectroscopy ◽  
Electrical Impedance ◽  
Radiation Injury ◽  
Electrical Impedance Spectroscopy ◽  
Non Invasive

scholarly journals Bone Fracture Detection by Electrical Bioimpedance: First Non-Invasive Measurements in Ex-Vivo Mammalian Femur

2019 ◽  
Author(s):  
A. H. Dell’Osa ◽  
A. Concu ◽  
F. R. Dobarro ◽  
J. C. Felice
Keyword(s):  
Impedance Spectroscopy ◽  
Electrical Impedance ◽  
Bone Fractures ◽  
Ex Vivo ◽  
Fracture Site ◽  
Electrical Impedance Spectroscopy ◽  
X Rays ◽  
Fracture Detection ◽  
Real Component ◽  
Non Invasive

AbstractThe fracture of long bones is one of the pathologies of greater demand of systems of medical emergencies, the method used for the diagnosis, the radiology of X-rays, produces damages to the patients and to the hospitals environment. For these reasons, our group is studying the implementation of a new diagnostic technique for the detection of bone fractures by bioimpedance measurements. To simulate a limb, two phantom of bovine femurs (the one with an entire bone and the other with a sawn bone) were constructed and non-invasive Electrical Impedance Spectroscopy measurements were taken on them in order to identify differences in their respective Cole Cole diagrams. Impedance spectroscopy was performed by a frequency sweep between 1 Hz and 65 kHz at a fixed current of 1 mA. The results obtained show wide differences in the Cole Cole diagrams of both phantoms (entire and fractured bone), especially concerning the real component of the, which latter, around the bones section corresponding to that of the lesion in both femurs, was always lower in the fractured femur than the entire one. These first superficial (non-invasive) measurements correspond to the electrical impedance spectroscopy bases and these could -in turn- correspond to what occurs in mammals immediately after the fracture happens, i. e. a dramatic increase in electrical conductivity due to diffusion into the fracture site of more conductive materials such as the blood and the extravascular fluids.

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