scholarly journals The Effects of Exercise Induced Muscle Damage on Knee Joint Torque and Balance Performance

Sports ◽  
2018 ◽  
Vol 6 (3) ◽  
pp. 101
Author(s):  
Nicole Dabbs ◽  
Harish Chander
Keyword(s):  
Knee Joint ◽  
Muscle Damage ◽  
Repeated Measures ◽  
Time Effect ◽  
Joint Torque ◽  
Knee Extensors ◽  
Balance Performance ◽  
Significant Time ◽  
Significant Time Effect ◽  
Exercise Induced

The purpose of this investigation is to determine the effects of exercise induced muscle damage (EIMD) on balance and knee joint torque. Thirteen males and females volunteered to participate in the study. Following a familiarization session, baseline measures were obtained for isometric torque measured during a maximal voluntary isometric contraction (MVIC) for knee flexors and extensors, and ankle dorsi-flexors and plantar-flexors. Additionally, balance performance was tested in double leg (DL), and right single leg (RSL) static and dynamic unstable stability was measured. Participants then performed the muscle damage protocol of front loaded Bulgarian split squats. All measurements were re-assessed for torque and balance immediately and up to 72 h afterwards. A one-way repeated-measures analysis of variance (ANOVA) was used to analyze differences between baseline and all time-points for torque and balance measures. There was a significant time effect for knee extensors MVIC torque, where baseline measures are greater than post EIMD, 24 h and 48 h post EIMD. There was no significant time effect for all balance conditions. These results provide evidence of EIMD following high intensity eccentric exercises with significant reductions in knee extensor torque up to at least 48 h and show that balance was not compromised following EIMD.

Physical and functional well-being in women with breast cancer taking gabapentin for hot flashes.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. 9141-9141
Author(s):  
Kavita Dayal Chandwani ◽  
Joseph Roscoe ◽  
Charles E Heckler ◽  
Supriya Gupta Mohile ◽  
Karen Michelle Mustian ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Mixed Model ◽  
Linear Mixed Model ◽  
Hot Flashes ◽  
Well Being ◽  
Time Effect ◽  
Slight Reduction ◽  
Modest Improvement ◽  
Significant Time ◽  
Significant Time Effect

9141 Background: Hot flashes reduce quality of life (QOL) in women with breast cancer. In a randomized, double-blind, placebo-controlled trial of gabapentin for hot flashes, 900 mg of the drug was found to reduce hot flashes in women with breast cancer; however, their QOL of has not been studied. We conducted secondary analyses to study two domains of QOL: physical (PWB) and functional well-being (FWB) in women in this trial. Methods: A nationwide sample of women with breast cancer and hot flashes ≥ 2/day was studied at baseline (T1), 4 weeks (T2), and 8 weeks (T3) of treatment with gabapentin 300mg/day (G300) and 900mg/day (G900) in divided doses, and a matching placebo (PL). PWB and FWB were assessed via subscales of the Functional Assessment of Cancer Therapy-Breast. Linear mixed model analyses of PWB and FWB were conducted, adjusted for demographic and treatment variables. Results: The mean age of women (N=384) was 54.9 years ± 8.07 (range: 31-81, 72% >50 years); 76% were married; 71% had more than high school education; 95% were Caucasian and 3% African-American; 10% were undergoing chemotherapy, and 9% radiotherapy (RT). PWB showed significant time effect (p<.0001) and interaction of time and treatment (p<.0001). There was an improvement in PWB in the G300 by T2 with no change at T3, while the improvement in PL and G900 was more modest at T2 and continued at T3 (PL - T1 20.7, T2 21.2, T3 21.6; G300 - T1 20.9, T2 22.2, T3 22.2; and G900 - T1 21.2, T2 21.5, T3 21.7). FWB also showed a significant time effect (p=.001) and interaction of time and treatment (p<.002). FWB in G300 improved by T2, with no additional improvement at T3; it was unchanged in G900 at T2 with a slight reduction at T3; PL showed a modest improvement at T2 followed by a modest worsening at T3 (PL - T1 17.8, T2 18.1, T3 17.9; G300 - T1 17.9, T2 18.6, T3 18.6; G900 - T1 18.6, T2 18.6, T3 18.5). Conclusions: As reported previously, G900 is effective in reducing hot flashes. In this analysis, however, PWB and FWB showed different patterns of change over time between the two gabapentin and placebo groups with G900 showing minimal effects on PWB and FWB. Future trials to further study the changes in physical and functional well-being of women with breast cancer taking gabapentin for hot flashes are needed.

Protective effect by maximal isometric contractions against maximal eccentric exercise-induced muscle damage of the knee extensors

2016 ◽  
Vol 24 (3) ◽  
pp. 228-241 ◽  
Author(s):  
Kuo-Wei Tseng ◽  
Wei-Chin Tseng ◽  
Ming-Ju Lin ◽  
Hsin-Lian Chen ◽  
Kazunori Nosaka ◽  
...  
Keyword(s):  
Protective Effect ◽  
Muscle Damage ◽  
Eccentric Exercise ◽  
Knee Extensors ◽  
Isometric Contractions ◽  
Exercise Induced

scholarly journals Effects of Isometric Contractions on Eccentric Exercise-induced Muscle Damage of the Knee Extensors

2018 ◽  
Vol 50 (5S) ◽  
pp. 677-678
Author(s):  
Kun-Xian Lin ◽  
Hsiu-Hua Wang ◽  
Kuo-Wei Tseng ◽  
Wei-Chin Tseng ◽  
Ming-Ju Lin
Keyword(s):  
Muscle Damage ◽  
Eccentric Exercise ◽  
Knee Extensors ◽  
Isometric Contractions ◽  
Exercise Induced

Uncertainty of knee joint muscle activity during knee joint torque exertion: the significance of controlling adjacent joint torque

2005 ◽  
Vol 99 (3) ◽  
pp. 1093-1103 ◽  
Author(s):  
Daichi Nozaki ◽  
Kimitaka Nakazawa ◽  
Masami Akai
Keyword(s):  
Knee Joint ◽  
Hip Joint ◽  
Muscle Activity ◽  
Internal Variability ◽  
Knee Extension ◽  
Activity Level ◽  
Joint Torque ◽  
Knee Extensors ◽  
Joint Torques ◽  
Custom Made

In the single-joint torque exertion task, which has been widely used to control muscle activity, only the relevant joint torque is specified. However, the neglect of the neighboring joint could make the procedure unreliable, considering our previous result that even monoarticular muscle activity level is indefinite without specifying the adjacent joint torque. Here we examined the amount of hip joint torque generated with knee joint torque and its influence on the activity of the knee joint muscles. Twelve healthy subjects were requested to exert various levels of isometric knee joint torque. The knee and hip joint torques were obtained by using a custom-made device. Because no information about hip joint torque was provided to the subjects, the hip joint torque measured here was a secondary one associated with the task. The amount of hip joint torque varied among subjects, indicating that they adopted various strategies to achieve the task. In some subjects, there was a considerable internal variability in the hip joint torque. Such variability was not negligible, because the knee joint muscle activity level with respect to the knee joint torque, as quantified by surface electromyography (EMG), changed significantly when the subjects were requested to change the strategy. This change occurred in a very systematic manner: in the case of the knee extension, as the hip flexion torque was larger, the activity of mono- and biarticular knee extensors decreased and increased, respectively. These results indicate that the conventional single knee joint torque exertion has the drawback that the intersubject and/or intertrial variability is inevitable in the relative contribution among mono- and biarticular muscles because of the uncertainty of the hip joint torque. We discuss that the viewpoint that both joint torques need to be considered will bring insights into various controversial problems such as the shape of the EMG-force relationship, neural factors that help determine the effect of muscle strength training, and so on.

scholarly journals Altered Drop Jump Landing Biomechanics Following Eccentric Exercise-Induced Muscle Damage

Sports ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 24
Author(s):  
Themistoklis Tsatalas ◽  
Evangeli Karampina ◽  
Minas A. Mina ◽  
Dimitrios A. Patikas ◽  
Vasiliki C. Laschou ◽  
...  
Keyword(s):  
Muscle Damage ◽  
Eccentric Exercise ◽  
Muscle Soreness ◽  
Reaction Force ◽  
Knee Extensors ◽  
Jump Landing ◽  
Landing Biomechanics ◽  
Peak Knee ◽  
Exercise Induced ◽  
Kinematics And Kinetics

Limited research exists in the literature regarding the biomechanics of the jump-landing sequence in individuals that experience symptoms of muscle damage. The present study investigated the effects of knee localized muscle damage on sagittal plane landing biomechanics during drop vertical jump (DVJ). Thirteen regional level athletes performed five sets of 15 maximal eccentric voluntary contractions of the knee extensors of both legs at 60°/s. Pelvic and lower body kinematics and kinetics were measured pre- and 48 h post-eccentric exercise. The examination of muscle damage indicators included isometric torque, muscle soreness, and serum creatine kinase (CK) activity. The results revealed that all indicators changed significantly following eccentric exercise (p < 0.05). Peak knee and hip joint flexion as well as peak anterior pelvic tilt significantly increased, whereas vertical ground reaction force (GRF), internal knee extension moment, and knee joint stiffness significantly decreased during landing (p < 0.05). Therefore, the participants displayed a softer landing pattern following knee-localized eccentric exercise while being in a muscle-damaged state. This observation provides new insights on how the DVJ landing kinematics and kinetics alter to compensate the impaired function of the knee extensors following exercise-induced muscle damage (EIMD) and residual muscle soreness 48 h post-exercise.

Kinesiotaping Diminishes Delayed Muscle Soreness but does not Improve Muscular Performance

2020 ◽  
Vol 41 (09) ◽  
pp. 596-602
Author(s):  
Maria Alejandra Camacho ◽  
Esperanza Herrera ◽  
Jose Angelo Barela ◽  
Diana Carolina Delgado-Diaz
Keyword(s):  
Muscle Damage ◽  
Repeated Measures ◽  
Muscle Soreness ◽  
Peak Torque ◽  
Activity Level ◽  
Muscle Performance ◽  
Muscular Performance ◽  
Muscular Work ◽  
Intensity Perception ◽  
Exercise Induced

AbstractThis study aimed at determining the effect of kinesio-taping (KT) on muscle performance and delayed onset muscle soreness (DOMS) after exercise induced muscle damaged. Sixty-six healthy men volunteered to participate (age:18–25 y/o), who performed 200 isokinetic lengthening contractions of the dominant quadriceps. Then subjects were randomized to either control (no treatment), sham (no tape tension), or KT (10% tape tension) groups. Muscle performance was assessed by peak torque and muscular work during maximal isometric and concentric isokinetic contractions. DOMS intensity was assessed using a visual analog scale. Measurements were taken pre-exercise (Pre), 48 h and 96 h post-exercise. Repeated measures ANOVA was used for comparisons within group, and ANCOVA for comparisons among groups. Muscle damage was confirmed in all participants by an increase in CK activity level (p<0.01). Decrease in isometric and isokinetic peak torque was detected at 48 h in the control and sham groups (p<0.01). Muscular work decreased in all groups at 48 h (p<0.01). No differences between groups were detected in muscular performance variables. Increase in DOMS intensity was determined in all groups at 48 h. Comparisons between groups showed lower DOMS intensity in the KT group at 48 h. KT decreased DOMS intensity perception after exercise-induced muscle damage; however, it did not impact muscular performance.

scholarly journals Exercise-Induced Muscle Damage and Recovery in Young and Middle-Aged Males with Different Resistance Training Experience

Sports ◽  
2019 ◽  
Vol 7 (6) ◽  
pp. 132 ◽  
Author(s):  
John Fernandes ◽  
Kevin Lamb ◽  
Craig Twist
Keyword(s):  
Resistance Training ◽  
Muscle Damage ◽  
Peak Power ◽  
Time Course ◽  
Voluntary Contraction ◽  
Voluntary Activation ◽  
Knee Extensors ◽  
Middle Aged ◽  
Training Experience ◽  
Exercise Induced

This study compared the time course of recovery after a squatting exercise in trained young (YG; n = 9; age 22.3 ± 1.7 years) and trained (MT; n = 9; 39.9 ± 6.2 years) and untrained (MU; n = 9; age 44.4 ± 6.3 years) middle-aged males. Before and at 24 and 72 h after 10 × 10 squats at 60% one-repetition maximum (1RM), participants provided measurements of perceived muscle soreness (VAS), creatine kinase (CK), maximal voluntary contraction (MVC), voluntary activation (VA), and resting doublet force of the knee extensors and squatting peak power at 20% and 80% 1RM. When compared to the YG males, the MT experienced likely and very likely moderate decrements in MVC, resting doublet force, and peak power at 20% and 80% 1RM accompanied by unclear differences in VAS, CK, and VA after the squatting exercise. MU males, compared to MT, experienced greater alterations in peak power at 20% and 80% 1RM and VAS. Alterations in CK, MVC, VA, and resting doublet force were unclear at all time-points between the middle-aged groups. Middle-aged males experienced greater symptoms of muscle damage and an impaired recovery profile than young resistance trained males. Moreover, regardless of resistance training experience, middle-aged males are subject to similar symptoms after muscle-damaging lower-body exercise.

HOMA-IR increase after antidepressant treatment in depressed patients with the Met allele of the Val66Met BDNF genetic polymorphism

2018 ◽  
Vol 49 (14) ◽  
pp. 2364-2369
Author(s):  
Séverine Martin ◽  
Romain Colle ◽  
Khalil El Asmar ◽  
Adrien Rigal ◽  
Albane Vievard ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Antidepressant Treatment ◽  
Time Effect ◽  
Val66met Polymorphism ◽  
Significant Time ◽  
Depressed Patients ◽  
Significant Time Effect ◽  
Time Interaction ◽  
Bdnf Val66met Polymorphism ◽  
Fasting Glycaemia

AbstractBackgroundThe brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is associated with response to antidepressant drugs in depressed patients and with metabolic side effects after antipsychotic treatment. This study aims to assess the association between this polymorphism and insulin resistance after antidepressant treatment in depressed patients.MethodsOne hundred forty-eight Caucasian patients with a current unipolar major depressive episode (DSM IV-TR) were genotyped for the BDNF Val66Met polymorphism and assessed at baseline and after 3 and 6 months of antidepressant treatment for the ‘Homoeostasis model assessment of insulin resistance’ (HOMA-IR) index, a valid measure of insulin resistance based on fasting plasma insulinaemia and glycaemia. Because validity assumptions were fulfilled, data were analysed using analysis of variance for repeated measures.ResultsThe 52 (35%) Met carriers and 96 (65%) Val/Val patients were not different at baseline for clinical characteristics and HOMA-IR. A significant Val66Met × time interaction (p= 0.02), a significant time effect (p= 0.03) and a significant Val66Met effect (p= 0.0497) were shown for HOMA-IR. A significant Val66Met × time interaction (p= 0.01) and a significant time effect (p= 0.003) were shown for fasting glycaemia. HOMA-IR and fasting glycaemia changes after antidepressant treatment were significantly higher in Met carrier than in Val/Val patients (HOMA-IR changes: Met: 0.71 ± 3.29v.Val/Val: −0.16 ± 1.34,t= 2.3, df = 146,p= 0.02, glycaemia changes: Met: 0.09 ± 0.30v.Val/Val: 0.02 ± 0.16,t= −2.0, df = 146,p= 0.045).ConclusionsThe Met allele of the Val66Met BDNF polymorphism confers to depressed patients a higher risk of insulin-resistance after antidepressant treatment. These patients could benefit from specific monitoring of metabolism and preventive measures.

scholarly journals A Comparison of Exercise-Induced Muscle Damage Following Maximal Eccentric Contractions in Men and Boys

2017 ◽  
Vol 29 (3) ◽  
pp. 316-325 ◽  
Author(s):  
Chariklia K. Deli ◽  
Ioannis G. Fatouros ◽  
Vassilis Paschalis ◽  
Kalliopi Georgakouli ◽  
Athanasios Zalavras ◽  
...  
Keyword(s):  
Muscle Damage ◽  
Muscle Soreness ◽  
Isometric Force ◽  
Age Groups ◽  
Eccentric Contractions ◽  
Knee Extensors ◽  
Type Method ◽  
Healthy Men ◽  
Delayed Onset ◽  
Exercise Induced

Purpose:Research regarding exercise-induced muscle-damage mainly focuses on adults. The present study examined exercise-induced muscle-damage responses in adults compared with children.Method:Eleven healthy boys (10–12 y) and 15 healthy men (18–45 y) performed 5 sets of 15 maximal eccentric contractions of the knee extensors. Range of motion (ROM), delayed onset muscle soreness (DOMS) during squat and walking, and peak isometric, concentric and eccentric torque were assessed before, post, 24, 48, 72, and 96 hr postexercise. Creatine kinase (CK) activity was assessed before and 72 hr postexercise.Results:Eccentric exercise resulted in DOMS during squat that persisted for up to 96h in men, and 48 hr in boys (p < .05), and DOMS during walking that persisted for up to 72 hr in men, and 48 hr in boys (p < .01). The ROM was lower in both age groups 48 hr postexercise (p < .001). Isometric (p < .001), concentric (p < .01) and eccentric (p < .01) force decreased post, and up to 48 hr postexercise in men. Except for a reduction in isometric force immediately after exercise, no other changes occurred in boys’ isokinetic force. CK activity increased in men at 72 hr postexercise compared with pre exercise levels (p = .05).Conclusion:Our data provide further confirmation that children are less susceptible to exercise-induced muscle damage compared with adults.

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