scholarly journals Recent Advances in Organocatalyzed Asymmetric Synthesis of Benzopyran and Benzodihydropyran (Chromane) Nuclei

Symmetry ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 1510
Author(s):  
Renato Dalpozzo ◽  
Raffaella Mancuso
Keyword(s):  
Natural Products ◽  
Asymmetric Synthesis ◽  
Organic Synthesis ◽  
Building Blocks ◽  
Core Structure ◽  
The Core ◽  
Recent Advances ◽  
Set Up

Benzopyran and benzodihydropyran (chromane) nuclei are the core structure of many natural products, in particular flavonoids. Many compounds possessing this structure are nutraceuticals, pharmaceutical nutrients. Therefore, benzopyran and chromane scaffolds are important building blocks in organic synthesis and many efforts have been made to set up efficient methods for their synthesis. In particular, asymmetric methods are of great importance, being natural products, and generally chiral substances. This review aims to cover literature in the range 2017–first half of 2019.

Recent advances of chromone-based reactants in the catalytic asymmetric domino annulation reaction

2021 ◽  
Author(s):  
Min Zhang ◽  
Ying Gong ◽  
Wei Zhou ◽  
Ying Zhou ◽  
Xiong-Li Liu
Keyword(s):  
Natural Products ◽  
Building Blocks ◽  
Bioactive Molecules ◽  
The Core ◽  
Recent Advances ◽  
Catalytic Asymmetric

Chiral polycyclic chromanones are important heterocyclic frameworks that constitute the core structures of many natural products and bioactive molecules. As starting materials, the chromone-based reactants are very efficient building blocks...

Recent advances in the catalytic synthesis of 3-aminooxindoles: an update

2020 ◽  
Vol 18 (25) ◽  
pp. 4692-4708 ◽  
Author(s):  
Jasneet Kaur ◽  
Banni Preet Kaur ◽  
Swapandeep Singh Chimni
Keyword(s):  
Natural Products ◽  
Catalytic Synthesis ◽  
Biologically Active Compounds ◽  
Core Structure ◽  
Biologically Active ◽  
Active Compounds ◽  
The Core ◽  
Recent Advances

3-Substituted-3-aminooxindoles are versatile scaffolds and these motifs constitute the core structure of number of natural products and biologically active compounds.

scholarly journals Recent Advances in Palladium-Catalyzed Isocyanide Insertions

Molecules ◽  
2020 ◽  
Vol 25 (21) ◽  
pp. 4906
Author(s):  
Jurriën W. Collet ◽  
Thomas R. Roose ◽  
Bram Weijers ◽  
Bert U. W. Maes ◽  
Eelco Ruijter ◽  
...  
Keyword(s):  
Organic Synthesis ◽  
Building Blocks ◽  
Insertion Reactions ◽  
Chemical Reagents ◽  
The Past ◽  
Recent Advances ◽  
Recent Developments ◽  
Palladium Catalyzed ◽  
Made In ◽  
Rapid Incorporation

Isocyanides have long been known as versatile chemical reagents in organic synthesis. Their ambivalent nature also allows them to function as a CO-substitute in palladium-catalyzed cross couplings. Over the past decades, isocyanides have emerged as practical and versatile C1 building blocks, whose inherent N-substitution allows for the rapid incorporation of nitrogeneous fragments in a wide variety of products. Recent developments in palladium catalyzed isocyanide insertion reactions have significantly expanded the scope and applicability of these imidoylative cross-couplings. This review highlights the advances made in this field over the past eight years.

The Application of tert-Butanesulfinamide in the Asymmetric Synthesis of the Core Structure of Polyoxin and Nikkomycin Antibiotics

Synlett ◽  
2009 ◽  
Vol 2009 (05) ◽  
pp. 833-837 ◽  
Author(s):  
Peng-Fei Xu ◽  
Yong-Chun Luo ◽  
Huan-Huan Zhang
Keyword(s):  
Asymmetric Synthesis ◽  
Core Structure ◽  
The Core

scholarly journals Asymmetric synthesis of chiral cycloalkenone derivatives via palladium catalysis

2014 ◽  
Vol 5 (4) ◽  
pp. 1354-1360 ◽  
Author(s):  
Barry M. Trost ◽  
James T. Masters ◽  
Jean-Philip Lumb ◽  
Dahlia Fateen
Keyword(s):  
Natural Products ◽  
Asymmetric Synthesis ◽  
Palladium Catalysis ◽  
Building Blocks ◽  
Efficient Synthesis ◽  
Palladium Catalyzed

Palladium-catalyzed oxidative desymmetrization enables the efficient synthesis of both enantioenriched cycloalkenone building blocks and diverse epoxyquinoid natural products.

scholarly journals Strategies To Access γ-Hydroxy-γ-butyrolactams

Synthesis ◽  
2018 ◽  
Vol 50 (06) ◽  
pp. 1175-1198 ◽  
Author(s):  
Laurent Commeiras ◽  
Muhammad Idham Darussalam Mardjan ◽  
Jean-Luc Parrain
Keyword(s):  
Natural Products ◽  
Organic Synthesis ◽  
Broad Spectrum ◽  
Heterocyclic Compounds ◽  
Biological Activities ◽  
Building Blocks ◽  
Pharmaceutical Molecules

α,β-Unsaturated γ-hydroxy-γ-butyrolactams are of a great interest due to their presence in designed pharmaceutical molecules and numerous natural products displaying a broad spectrum of biological activities. In addition, these five-membered heterocyclic compounds are also relevant and versatile building blocks in organic synthesis. In this context, strategies for the construction of these scaffolds has triggered considerable attention and this review highlights the progress in the formation of α,β-unsaturated γ-hydroxy-γ-butyrolactams (5-hydroxy-1,5-dihydro-2H-pyrrol-2-ones).1 Introduction2 Intramolecular Routes3 Intermolecular Routes4 Oxidation of Heterocyclic Compounds5 Miscellaneous6 Conclusion

scholarly journals N-Propargylic β-enaminocarbonyls: powerful and versatile building blocks in organic synthesis

RSC Advances ◽  
2017 ◽  
Vol 7 (22) ◽  
pp. 13198-13211 ◽  
Author(s):  
Sattar Arshadi ◽  
Esmail Vessally ◽  
Ladan Edjlali ◽  
Ebrahim Ghorbani-Kalhor ◽  
Rahim Hosseinzadeh-Khanmiri
Keyword(s):  
Natural Products ◽  
Organic Synthesis ◽  
Heterocyclic Compounds ◽  
Building Blocks

Nitrogen-containing heterocyclic compounds are not only prevalent in an extensive number of natural products and synthetic pharmaceuticals but are also used as building blocks in organic synthesis.

Asymmetric Synthesis of the Core Structure of Leucosceptroids A–D

2011 ◽  
Vol 76 (15) ◽  
pp. 6169-6176 ◽  
Author(s):  
Jun Xie ◽  
Yuelong Ma ◽  
David A Horne
Keyword(s):  
Asymmetric Synthesis ◽  
Core Structure ◽  
The Core

ChemInform Abstract: Asymmetric Synthesis of the Core Structure of the Melodinus Alkaloids.

ChemInform ◽  
2010 ◽  
Vol 30 (17) ◽  
pp. no-no
Author(s):  
Arthur G. Schultz ◽  
Mingshi Dai
Keyword(s):  
Asymmetric Synthesis ◽  
Core Structure ◽  
The Core
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