scholarly journals A Case of Exacerbation of Subclinical Hyperthyroidism after First Administration of BNT162b2 mRNA COVID-19 Vaccine

Vaccines ◽  
2021 ◽  
Vol 9 (10) ◽  
pp. 1108
Author(s):  
Kana Yamamoto ◽  
Takahisa Mashiba ◽  
Keisuke Takano ◽  
Toshihiko Suzuki ◽  
Masahiro Kami ◽  
...  

COVID-19 vaccines are the most critical measure for controlling the COVID-19 pandemic; however, we have little information on their complications. We experienced a case of a patient who developed hyperthyroidism complicated with atrial fibrillation and heart failure on the sixth day after the first dose of COVID-19 vaccination. This case report shows the importance of considering hyperthyroidism as a possible complication after COVID-19 vaccination.

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Maureen Higgs ◽  
Erroll Hull ◽  
Eugenio Lujan

This is a case of thyrotoxicosis, due to the Jöd-Basedow phenomenon following administration of oral and IV iodinated contrast in a patient with history of gastrointestinal stromal tumor (GIST) and small bowel obstruction. The patient developed atrial fibrillation and had an extended stay in the intensive care unit. Given the aging population with possible subclinical hyperthyroidism, multinodular goiter, and the rise in contrast administration for routine diagnostic studies, this case serves to raise awareness of the risks of “routine” tests administered to our aging patient population.


2020 ◽  
Author(s):  
Javier Maldonado ◽  
German Molina ◽  
Francisco M- Rincón T ◽  
Lina M. Acosta Buitrago ◽  
Carlos J- Perez Rivera

Abstract Background: Large intracardiac bronchogenic cysts are rare mediastinal masses, however they must always be considered in the differential diagnosis of heart failure. Case Presentation: We present a 60-year-old female patient with de novo atrial fibrillation and heart failure, resulting from an incidental large intrapericardial mass. The patient underwent successful surgical resection, with pathological findings confirming a bronchogenic cyst.Conclusions: Large bronchogenic cysts located intrapericardially are very rare, however they should be included in the differential diagnosis of patients presenting with atrial fibrillation and heart failure.


2021 ◽  
Vol 9 (2) ◽  
pp. 38-42
Author(s):  
Hiroshi Bando ◽  
Naoki Kondo ◽  
Shigeki Hatakeyama ◽  
Junji Morita ◽  
Kazuki Sakamoto ◽  
...  

The patient was an 85-year-old female who has been treated for hypertension and atrial fibrillation (Af). She has visited outpatient clinic and has received regularly general blood tests for every six months. Hemoglobin (Hb) level was stable as 11.2-12.3 g/dL and MCV 88fL from 2017, but it decreased suddenly to 5.2 g/dL and 64 fL in Sept 2020. She did not feel any symptoms or signs. Further evaluations revealed that occult blood in stool and upper and endoscopic exams were negative. About 40 days after starting sodium ferrous citrate, she developed edema anasarca, bilateral pleural effusion and heart failure. Laboratory test showed hypothyroidism, and then the administration of thyroid hormone and diuretics brought her early improvement. As to this impressive case report, general clinical progress and some discussion of the relationship among anemia, edema anasarca, heart failure and hypothyroidism would be described.


2020 ◽  
Author(s):  
Thera P. Links ◽  
Trynke van der Boom ◽  
Wouter T. Zandee ◽  
Joop D Lefrandt

Thyroid hormone stimulates cardiac inotropy and chronotropy via direct genomic and non-genomic mechanisms. Hyperthyroidism magnifies these effects, resulting in an increase in heart rate, ejection fraction and blood volume. Hyperthyroidism also affects thrombogenesis and this may be linked to a probable tendency towards thrombosis in patients with hyperthyroidism. Patients with hyperthyroidism are therefore at higher risk for atrial fibrillation, heart failure and cardiovascular mortality. Similarly, TSH suppressive therapy for differentiated thyroid cancer is associated with increased cardiovascular risk. In this review, we present the latest insights on the cardiac effects of thyroid suppression therapy for the treatment of thyroid cancer. Finally, we will show new clinical data on how to implement this knowledge into the clinical practice of preventive medicine.


2017 ◽  
Vol 49 (10) ◽  
pp. 723-731 ◽  
Author(s):  
Alessandro Delitala

AbstractThyroid hormone excess has complex metabolic effects, particularly on the cardiovascular system. Treatment of these conditions is universally suggested by international guidelines. Subclinical hyperthyroidism, defined by reduced or suppressed TSH levels in the presence of normal free thyroxine and free triiodothyronine values, is common in the general population and progressively increases with aging, being as high as 15.4% in subjects more than 75 years old and more frequent in subjects with nodular goiter. Subclinical hyperthyroidism is often asymptomatic and the diagnosis is incidentally made during screening exams. However, this form of thyroid disorder has gained attention in the last years for its association with cardiovascular disease, in particular with atrial fibrillation. Less clear are the effects of subclinical hyperthyroidism on blood pressure, stroke, or heart failure. The decision to treat subclinical hyperthyroidism is made on the clinical judge, particularly in elderly patients and/or in the presence of comorbidities.


Author(s):  
Yi Fang ◽  
Zhiyuan Li ◽  
Jinjing Wang ◽  
Jianbin Su ◽  
Jing Zeng ◽  
...  

Tachycardia and atrial fibrillation are cardiovascular symptoms of Graves’ hyperthyroidism, if left untreated and further deterioration can result in heart failure and liver dysfunction, we describe a female patient to present the continuum of the pathophysiology development, to highlight the hemodynamic variation is dominant contributing factor of Graves’ hyperthyroidism complication


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