scholarly journals Intraneural synovial sarcoma of median nerve

2020 ◽  
pp. 110-115
Author(s):  
Sandeep Bhardwaj ◽  
Anil Kansal ◽  
Rohit Bansal ◽  
Rakesh Sharma ◽  
Akangsha Sharma
Keyword(s):  
Median Nerve ◽  
Synovial Sarcoma ◽  
Histopathological Examination ◽  
Soft Tissue Tumour ◽  
Rare Tumour ◽  
Nerve Sheath Tumour ◽  
Nerve Sheath ◽  
Tissue Tumour ◽  
Dismal Prognosis ◽  
Synovial Sarcomas

Synovial sarcomas are highly aggressive soft tissue tumour with a poor and dismal prognosis. These tumours have a high propensity for distant metastasis and local recurrence.  Although originally believed to arise from synovium, these tumours have been found to occur anywhere in body1,2. We report here, a case of median nerve sarcoma in a 15-year female. This is a rare tumour, which is diagnosed only after histopathological examination with only a few cases reported in the literature (Table 1). Although preoperatively tumour was thought to be a nerve sheath tumour, on histopathology analysis was found to be synovial sarcoma. Despite aggressive behaviour, wide local excision is recommended even in smaller lesions. So, the diagnosis should always be kept in differentials of nerve sheath tumour, as what may be a synovial sarcoma.

scholarly journals Intraneural synovial sarcoma of median nerve

2020 ◽  
pp. 275-279
Author(s):  
Sandeep Bhardwaj ◽  
Anil Kansal ◽  
Rohit Bansil ◽  
Rakesh Singh ◽  
Akangsha Sharma
Keyword(s):  
Median Nerve ◽  
Synovial Sarcoma ◽  
Histopathological Examination ◽  
Soft Tissue Tumour ◽  
Rare Tumour ◽  
Nerve Sheath Tumour ◽  
Nerve Sheath ◽  
Tissue Tumour ◽  
Dismal Prognosis ◽  
Synovial Sarcomas

Synovial sarcomas are highly aggressive soft tissue tumour with a poor and dismal prognosis. These tumours have a high propensity for distant metastasis and local recurrence.  Although originally believed to arise from synovium, these tumours have been found to occur anywhere in body [1],[2]. We report here, a case of median nerve sarcoma in a 15-year female. This is a rare tumour, which is diagnosed only after histopathological examination with only a few cases reported in the literature (Table 1). Although preoperatively tumour was thought to be a nerve sheath tumour, on histopathology analysis was found to be synovial sarcoma. Despite aggressive behaviour, wide local excision is recommended even in smaller lesions. So, the diagnosis should always be kept in differentials of nerve sheath tumour, as what may be a synovial sarcoma.

Rare case of angiofibroma presenting as perineal hernia

2021 ◽  
Vol 14 (1) ◽  
pp. e236661
Author(s):  
Ruchika Kumari ◽  
Cherring Tandup ◽  
Ambuj Agarwal ◽  
Anish Chowdhury
Keyword(s):  
Soft Tissue ◽  
Case Reports ◽  
En Bloc Resection ◽  
Perineal Hernia ◽  
Pathological Examination ◽  
Soft Tissue Tumour ◽  
Open Approach ◽  
En Bloc ◽  
Rare Tumour ◽  
Tissue Tumour

Angiofibroma is a benign soft tissue tumour presenting as a gradually progressive swelling in the vulvovaginal area in women and in the inguinoscrotal region in men. Being a rare tumour, there are only a few case reports in the literature, and among them, presentation as perineal herniation is very rare. En bloc resection of angiofibroma either via laparoscopic or open approach is the choice of treatment to avoid recurrence. Detailed pathological examination and immunohistochemistry workup are imperative to distinguish it from various mesenchymal tumours. Perineal hernia is itself rare and may occur spontaneously or following abdominoperineal resection, sacrectomy or pelvic exenteration. Surgical repair via open transabdominal and transperineal approaches has been described. Here, we report a case of a young woman who presented with spontaneous reducible perineal hernia with a soft tissue tumour as its content, which on histopathological investigation was found to be an angiofibroma.

Synovial Sarcoma of the Cervical Spine: Case Report

2021 ◽  
Author(s):  
Nuno Oliveira ◽  
Sofia Carvalho ◽  
Paulo Cunha ◽  
Joni Nunes ◽  
Pedro Varanda ◽  
...  
Keyword(s):  
Case Report ◽  
Cervical Spine ◽  
Soft Tissue ◽  
Synovial Sarcoma ◽  
Therapeutic Strategy ◽  
Osteolytic Lesion ◽  
Neurological Deficits ◽  
Soft Tissue Tumour ◽  
Tissue Tumour ◽  
Primary Bone

Abstract PurposeTo describe a very rare case of Synovial Sarcoma affecting cervical spine vertebra.SS is a rare malignant and aggressive soft tissue tumour arising from mesenchymal cells. Primary bone origin SS is a much rarer entity that affects more commonly long bones. Ideal therapeutic strategy is yet to be defined due to very small number of cases reported so far.Case reportA 55-year-old male, construction worker, with no other relevant medical history presented with a progressive tetraparesis after recurring several times during a 4-week period to assistant physician and emergency department complaining about bilateral shoulder pain. Image studies revealed an osteolytic lesion centred on C4 vertebra with intracanalar and intraforaminal extension, causing neurologic compression. Patient was submitted to urgent surgical decompression intervention. C3 and C4 corpectomy and excisional biopsy followed by stabilization with C2-C5 arthrodesis.OutcomesNeurological deficits did not improve after surgery. Histopathological and immunohistochemical analysis revealed phenotypical characteristics of a biphasic Synovial Sarcoma. Patient died 4 weeks after surgery due to a respiratory tract infection.DiscussionSS is a malignant rare and aggressive soft tissue tumour that usually affects young adults. Very few cases of primary bone SS affecting the spine are described in literature. Imaging studies may suggest the diagnosis of synovial sarcoma but definitive diagnosis can only be confirmed by histological and immunohistochemical analysis.The rarity of these lesions demands high clinical suspicion for the diagnosis and due to the low number of cases reported ideal therapeutic strategy is yet to be defined.

Malignant peripheral nerve sheath tumour of median nerve - an unusual presentation: a case report

2005 ◽  
Vol 28 (1) ◽  
pp. 50-52
Author(s):  
Rajive Mathew Jose ◽  
Danish Imran ◽  
Ramesh Vidyadharan ◽  
Paul K. Wright ◽  
G. S. Rao
Keyword(s):  
Case Report ◽  
Peripheral Nerve ◽  
Median Nerve ◽  
Unusual Presentation ◽  
Nerve Sheath Tumour ◽  
Nerve Sheath ◽  
Peripheral Nerve Sheath Tumour

scholarly journals Surgical excision of complex lipoma from the foot: a case report 

2020 ◽  
Author(s):  
Akram Uddin ◽  
George Flanagan ◽  
Ian Reilly
Keyword(s):  
Soft Tissue ◽  
Diagnostic Imaging ◽  
Histopathological Examination ◽  
Histopathological Analysis ◽  
Soft Tissue Tumour ◽  
Foot And Ankle ◽  
Level Of Evidence ◽  
Plantar Aspect ◽  
Tissue Tumour ◽  
Patient Reported

Abstract Background: Soft tissue malignant tumours of the foot and ankle are rare. Diagnostic imaging and interventional biopsy are vital to establish the nature and grading of a suspicious tumour prior to surgical intervention. The purpose of the study is to provide an account on how a symptomatic mass to the plantar aspect of the foot warranted a referral to a sarcoma centre, highlighting the importance of having urgent access to diagnostic imaging and a pathway to refer suspected cases to specialist centres. Method: A single patient with a symptomatic soft tissue tumour of the plantar foot was referred from our service to the regional sarcoma centre. It was considered to be benign and therefore open surgical resection was performed under local anaesthesia by our team, and the lesion sent for histopathological examination. Results: Histopathological analysis identified the excised mass as a lipoma to show no atypia or necrosis and mature adipose tissue with fibrous bands. At 2 years postoperatively there was no recurrence and the patient presented an asymptomatic foot. Favourable patient reported outcomes measures were observed. Conclusion: United Kingdom (UK) Guidelines suggest that all soft tissue masses of suspicious nature, greater than 50mm, deep seated irrespective of size, or fast growing should be referred to a sarcoma unit prior to surgical management. European guidance identifies a threshold of 15mm for a mass in the foot. Patients presenting with red flag symptoms irrespective of size of mass should be referred to a sarcoma centre. Advanced imaging and multidisciplinary input to enable appropriate surgical planning is recommended for these soft tissue tumours that present to the foot and ankle surgeon.Level of evidence: V case study.

Intraneural Synovial Sarcoma of the Median Nerve in a 15-Year-Old Male: A Case Report and Review of Literature

Hand ◽  
2021 ◽  
pp. 155894472097513
Author(s):  
Arthur Samia ◽  
Joshua Scarcella ◽  
Richard Zeri ◽  
Yifan Guo
Keyword(s):  
Median Nerve ◽  
Synovial Sarcoma ◽  
Thenar Eminence ◽  
Right Hand ◽  
History Of ◽  
Synovial Sarcomas ◽  
Poorly Differentiated ◽  
Web Space ◽  
The Right

There have been 8 synovial sarcomas of the median nerve reported. We report a case of a 15-year-old male with synovial sarcoma of the right-hand median nerve. Patient presented with a 2-month history of enlarging mass at the base of the right thenar eminence associated with numbness in the median nerve distribution. Physical examination revealed a soft mass over the thenar eminence and paresthesia in the median nerve distribution. He underwent excision of the tumor, which revealed a well-encapsulated lesion encompassing the median nerve, involving the first, second, and radial aspect of the third web space as well as recurrent branches of the median nerve. Following excision of the tumor, a thorough metastatic workup was negative for metastatic disease. He was staged as III, T2b, N0, M0—poorly differentiated monophasic synovial sarcoma of the right median nerve. Postoperatively the patient was started on chemotherapy and radiation. Intraneural synovial sarcoma is extremely rare. Our case is the youngest with the longest follow-up. He is currently at a status of 3 years posttreatment with no signs of recurrence and excellent use of his right hand. This case is of particular interest due to the rarity of the disease along with this being the best outcome reported in the literature to-date.

scholarly journals Malignant Peripheral Nerve Sheath Tumour of the Maxilla

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Puja Sahai ◽  
Bidhu Kalyan Mohanti ◽  
Devajit Nath ◽  
Suman Bhasker ◽  
Subhash Chander ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Histopathological Examination ◽  
Present Report ◽  
Neck Region ◽  
Future Research ◽  
Resected Specimen ◽  
Nerve Sheath Tumour ◽  
Nerve Sheath ◽  
Local Tumour ◽  
Peripheral Nerve Sheath Tumour

A 38-year-old man was diagnosed with malignant peripheral nerve sheath tumour of the maxilla. He was treated with total maxillectomy. Histopathological examination of the resected specimen revealed a close resection margin. The tumour was of high grade with an MIB-1 labelling index of almost 60%. At six weeks following the surgery, he developed local tumour relapse. The patient succumbed to the disease at five months from the time of diagnosis. The present report underlines the locally aggressive nature of malignant peripheral nerve sheath tumour of the maxilla which necessitates an early therapeutic intervention. A complete resection with clear margins is the most important prognostic factor for malignant peripheral nerve sheath tumour in the head and neck region. Adjuvant radiotherapy may be considered to improve the local control. Future research may demarcate the role of targeted therapy for patients with malignant peripheral nerve sheath tumour.

Gossypiboma mimicking a distal pancreatic mass: Report of a case

Open Medicine ◽  
2010 ◽  
Vol 5 (1) ◽  
pp. 136-139 ◽  
Author(s):  
Savas Yakan ◽  
Safak Oztürk ◽  
Mustafa Harman ◽  
Oktay Tekesin ◽  
Ahmet Coker
Keyword(s):  
Histopathological Examination ◽  
Abdominal Mass ◽  
The Body ◽  
Mass Lesion ◽  
Soft Tissue Tumour ◽  
Peptic Ulcer Perforation ◽  
Palpable Mass ◽  
Tissue Tumour ◽  
Splenic Hilus ◽  
Greater Curvature

AbstractGossypiboma (retained surgical sponge) is a pseudotumor within the body that is composed of non-absorbable surgical material with a cotton matrix. Because the symptoms of gossypiboma usually are nonspecific and may appear years after surgery, the diagnosis of gossypiboma may be difficult because the condition may mimic a benign or malignant soft-tissue tumour in the abdomen and pelvis. A 61-year-old woman with a one-year history of left upper-quadrant pain and weight loss was referred to our center. She had undergone peptic ulcer perforation 23 year ago. Physical examination revealed dullness and palpable mass in the left upper abdomen. On examination by computed tomography (CT), a hypodense mass of 12 cm in diameter between the greater curvature of the stomach, pancreas, and splenic hilus was detected. Upon exploration, a mass lesion of 10 cm in diameter was detected between the greater curvature of the stomach and splenic hilus, which caused dense adhesions not in communication with the pancreas. It was excised and a splenectomy was performed. After a macroscopic examination, the mass lesion was diagnosed as gossypiboma. Although ultrasonography (US), CT, angiography, and magnetic resonance imaging (MRI) may be used to diagnose gossypiboma, definitive diagnosis is possibile only upon surgery or histopathological examination. As a result, when an abdominal mass is observed, surgeons should carefully investigate the patient’s past surgical history while taking the possibility of gossypiboma into consideration.

Interdigitating dendritic cell sarcoma of the parotid gland

2005 ◽  
Vol 120 (3) ◽  
pp. 244-246 ◽  
Author(s):  
M Sharma ◽  
F Ahsan ◽  
K W Ah-See ◽  
M E McKean ◽  
R Kain ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Dendritic Cell ◽  
Parotid Gland ◽  
Histopathological Examination ◽  
Single Case ◽  
Needle Aspiration ◽  
Soft Tissue Tumour ◽  
Dendritic Cell Sarcoma ◽  
Single Case Report ◽  
Tissue Tumour

Interdigitating dendritic cell sarcomas (IDCSs) are extremely uncommon tumours that arise predominantly in lymphoid tissue. We report a case of an IDCS arising in the parotid gland of a 73-year-old man. Clinically, a primary salivary gland tumour was suspected but fine needle aspiration cytology suggested a soft tissue tumour. A diagnosis of IDCS was made on histopathological examination of the resection specimen, with subsequent confirmation by electron microscopy. Given the extreme rarity of this tumour at this site, it is unlikely to be a common diagnostic problem, but the importance of multiple diagnostic modalities is emphasized. The findings of cytology, histology, immunohistochemistry and electron microscopy have not previously been described together in a single case report of this tumour.

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