Faculty Opinions recommendation of An fMRI-based neurologic signature of physical pain.

Author(s):  
Ben Seymour
Keyword(s):  
Crisis ◽  
2019 ◽  
Vol 40 (6) ◽  
pp. 413-421 ◽  
Author(s):  
Megan L. Rogers ◽  
Thomas E. Joiner

Abstract. Background: Acute suicidal affective disturbance (ASAD) has been proposed as a suicide-specific entity that confers risk for imminent suicidal behavior. Preliminary evidence suggests that ASAD is associated with suicidal behavior beyond a number of factors; however, no study to date has examined potential moderating variables.  Aims: The present study tested the hypotheses that physical pain persistence would moderate the relationship between ASAD and (1) lifetime suicide attempts and (2) attempt lethality. Method: Students ( N = 167) with a history of suicidality completed self-report measures assessing the lifetime worst-point ASAD episode and the presence of a lifetime suicide attempt, a clinical interview about attempt lethality, and a physical pain tolerance task. Results: Physical pain persistence was a significant moderator of the association between ASAD and lifetime suicide attempts ( B = 0.00001, SE = 0.000004, p = .032), such that the relationship between ASAD and suicide attempts strengthened at increasing levels of pain persistence. The interaction between ASAD and pain persistence in relation to attempt lethality was nonsignificant ( B = 0.000004, SE = 0.00001, p = .765). Limitations: This study included a cross-sectional/retrospective analysis of worst-point ASAD symptoms, current physical pain perception, and lifetime suicide attempts. Conclusion: ASAD may confer risk for suicidal behavior most strongly at higher levels of pain persistence, whereas ASAD and pain perception do not influence attempt lethality.


2007 ◽  
Author(s):  
Rebecca M. Pasillas ◽  
Mark Stalnaker ◽  
Jason Deviva ◽  
Andrew Santanello ◽  
Melissa Decker ◽  
...  

Author(s):  
Paolo Riva ◽  
James H. Wirth ◽  
Kipling D. Williams

Author(s):  
Bridget Heal

Chapter 5 focuses on one particular type of Lutheran devotional image: the crucifix. It examines transformations in Lutheran Passion piety from the early Reformation to the era of Paul Gerhardt (1607–76), using this to illustrate the increasing significance accorded to images. Luther himself had condemned the excesses of late-medieval Passion piety, with its emphasis on compassion for Christ and the Virgin Mary, on physical pain and on tears. From the later sixteenth century onwards, however, Lutheran sermons, devotional literature, prayers and poetry described Christ’s suffering in increasingly graphic terms. Alongside this, late-medieval images of the Passion were restored and new images were produced. Drawing on case studies from the Erzgebirge, a prosperous mining region in southern Saxony, and Upper Lusatia, the chapter investigates the ways in which images of the Passion were used in Lutheran communities during the seventeenth century.


Author(s):  
Daniel King

Much of the Western intellectual tradition’s interest in pain can be traced back to Greek material. This book investigates one theme in the interest in physical pain in Greek culture under the Roman Empire. Traditional accounts of pain in the Roman Empire have either focused on philosophical or medical theories of pain or on Christian notions of ‘suffering’; and fascination with the pained body has often been assumed to be a characteristic of Christian society, rather than ancient culture in general. The book uses ideas from medical anthropology, as well as contemporary philosophical discussions and cultural theory, to help unpack the complex engagement with pain in the ancient world. It argues, centrally, that pain was approached as a type of embodied experience, in which ideas about the body’s physiology, its representation, and communication, as well as its emotional and cognitive impact on those who felt pain and others around them, were important aspects of what it meant to be in pain. The formulation of this sense of pain experience is examined across a range of important areas of Imperial Greek culture, including rational medicine, rhetoric, and literature, as well as ancient art criticism. What is common across these disparate areas of cultural activity is the notion that pain must be understood within its broad personal, social, and emotional context.


Author(s):  
Anita L. Vangelisti ◽  
Nicholas Brody

Social pain and physical pain have historically been conceptualized as distinct phenomena. Recent research, however, has noted several similarities between the two. The present chapter establishes the physiological basis of social pain. Further, the chapter explores the relational precedents and correlates of social pain. By synthesizing research that explores definitional elements of social pain, the reviewed literature explores the social basis of hurt. The chapter also reviews the extant research that posits similarities in the neural processing of social and physical pain. These similarities are further explained by examining findings that have emphasized parallels between cognitive, behavioral, and physiological responses to both social and physical pain. Shortcomings in the current research are reviewed, and several future directions are offered for researchers interested in the physiology of social pain.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Alan M. Daniel ◽  
Brenda G. Rushing ◽  
Karla Y. Tapia Menchaca

AbstractUnderstanding the emotional reaction to loss, or frustration, is a critical problem for the field of mental health. Animal models of loss have pointed to the opioid system as a nexus of frustration, physical pain, and substance abuse. However, few attempts have been made to connect the results of animal models of loss to human behavior. Allelic differences in the human mu opioid receptor gene, notably the A118G single nucleotide polymorphism, have been linked to individual differences in pain sensitivity, depressive symptoms, and reward processing. The present study explored the relationship between A118G and behavior in two frustrating tasks in humans. Results showed that carriers of the mutant G-allele were slower to recover behavior following a reward downshift and abandoned a frustrating task earlier than those without the mutation. Additionally, G-carriers were more sensitive to physical pain. These results highlight the overlap between frustration and pain, and suggest that genetic variation in opioid tone may contribute to individual differences in vulnerability and resilience following emotional disturbances.


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