Manifestações bucais em pacientes com leucemia / Oral manifestation in patients with leukemia

Linear gingival erythema (LGE), formally referred as HIV-gingivitis, is the most common form of HIV-associated periodontal disease in HIV-infection. These lesions were recently evaluated as a possible form of erythematous oral candidosis, mainly caused by Candida albicans. Other species are also being associated such as C. tropicalis, C. stellatoidea, C. krusei, C. parapsilosis, C. glabrata and C. dubliniensis, that was identified in some HIV-infected subjects. This case report demonstrates the presence of typical LGE lesions in six HIV-infected children, also investigates the etiologic agent by microbiological exams and correlates this oral manifestation with patients’ systemic conditions. Microbiological analyses showed positive growth for Candida spp in all patients, all of whom had severe imunessupression. After antifungal medication, the regression of lesions could be note. The presence of LGE in pediatric patients with AIDS may indicate its feature as a predictive marker in progression of HIV-infection in children.

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Saprochaete clavata Infection in Immunosuppressed Patients: Systematic Review of Cases and Report of the First Oral Manifestation, Focusing on Differential Diagnosis

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18052385 ◽

2021 ◽

Vol 18 (5) ◽

pp. 2385

Author(s):

Carlo Lajolo ◽

Rupe Cosimo ◽

Schiavelli Anna ◽

Gioco Gioele ◽

Metafuni Elisabetta ◽

...

Keyword(s):

Risk Factors ◽

Systematic Review ◽

Acute Myeloid Leukemia ◽

Differential Diagnosis ◽

Myeloid Leukemia ◽

Oral Manifestation ◽

First Case ◽

Immunosuppressed Patients ◽

Meta Analyses ◽

Acute Myeloid

Background: Saprochaete clavata infection is an emerging issue in immunosuppressed patients, causing fulminant fungaemia. The purpose of this systematic review of cases is to retrieve all cases of S. clavata infection and describe oral lesions as the first manifestation of S. clavata infection. Methods: We report the first case of intraoral S. clavata infection in Acute Myeloid Leukemia (AML) affected subject, presenting as multiple grayish rapidly growing ulcerated swellings, and provide a review of all published cases of infection caused by S. clavata, according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, conducted by searching SCOPUS, Medline, and CENTRAL databases. Only articles in English were considered. Individual patient data were analyzed to identify risk factors for S. clavata infection. Results: Seventeen of 68 retrieved articles were included in the review reporting data on 96 patients (mean age 51.8 years, 57 males and 38 females). Most cases were disseminated (86) with a 60.2% mortality rate. Ninety-five were hematological patients, with AML being the most common (57 cases). Conclusions:S. clavata infection in immunosuppressed patients has a poor prognosis: middle-age patients, male gender and Acute Myeloid Leukemia should be considered risk factors. In immunosuppressed patients, the clinical presentation can be particularly unusual, imposing difficult differential diagnosis, as in the reported case.

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Diagnosis of leprosy through an oral manifestation

Oral Surgery Oral Medicine Oral Pathology and Oral Radiology ◽

10.1016/j.oooo.2012.08.335 ◽

2012 ◽

Vol 114 (4) ◽

pp. e115

Keyword(s):

Oral Manifestation

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Crohn's disease - oral manifestation in patients on a clinical remission phase

Oral Surgery Oral Medicine Oral Pathology and Oral Radiology ◽

10.1016/j.oooo.2012.08.097 ◽

2012 ◽

Vol 114 (4) ◽

pp. e62

Keyword(s):

Crohn’S Disease ◽

Crohn's Disease ◽

Clinical Remission ◽

Oral Manifestation ◽

Remission Phase

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Why Oral Medicine is an exemplary choice for specialty? A Comprehensive Review

10.37191/mapsci-jdr-2(1)-014 ◽

2021 ◽

Author(s):

Shibani Sahni

Keyword(s):

Clinical Skills ◽

Systemic Disease ◽

Specialty Training ◽

Oral Medicine ◽

New Techniques ◽

Oral Manifestation ◽

Complex Patients ◽

Wide Range ◽

Future Direction ◽

Definition Of

The purpose of this article was to describe a narrative review of the literature for understanding the reasons behind Oral Medicine gaining popularity as a choice for post graduate specialty training. Oral Medicine is the intersection of medicine and dentistry, and the clinicians are responsible for the management of oral mucosal disease, salivary gland dysfunction and oral manifestation of systemic disease, and facial pain in the definition of oral medicine and hence having a wide range of responsibilities. Breadth of knowledge on medically complex patients for example, rheumatologic, cardiovascular, cancer, endocrine, immuno-deficiency patients is required, which makes it an extremely interesting specialty and enables the clinicians to provide interdisciplinary care to the patients. It is important for dental education to foster new techniques in learning and preparing the students for clinical skills prior to patient care. The scope of impact of Oral Medicine has increased over the years, leading to it gaining popularity amongst dentists to take it up as a specialty training. The future direction of the study will be to understand how to enhance the research, clinical practice, and education for Oral Medicine.

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Neurofibromatosis: an unusual oral manifestation

BDJ ◽

10.1038/sj.bdj.4807510 ◽

1991 ◽

Vol 170 (8) ◽

pp. 303-304 ◽

Cited By ~ 2

Author(s):

D L Gutteridge

Keyword(s):

Oral Manifestation

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Disseminated Histoplasmosis with Oral Manifestation in an Immunocompetent Patient

Case Reports in Dentistry ◽

10.1155/2017/1323514 ◽

2017 ◽

Vol 2017 ◽

pp. 1-4 ◽

Cited By ~ 2

Author(s):

Debopriya Chatterjee ◽

Aishwarya Chatterjee ◽

Manoj Agarwal ◽

Meetu Mathur ◽

Setu Mathur ◽

...

Keyword(s):

Case Report ◽

Female Patient ◽

Immunocompetent Patient ◽

Oral Manifestation ◽

Disseminated Histoplasmosis

A case of disseminated histoplasmosis (DH) in a 60-year-old female patient is reported from Jaipur, Rajasthan, India. The patient presented with multiple papules on the skin surrounding the lips, face, torso, trunk, and back. She also complained of growth in the palate. Histoplasmosis was confirmed by biopsy and histopathology of skin and palatal lesions. This case report highlights the presenting features and occurrence of histoplasmosis in nonendemic region in India.

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ORAL SECONDARY INFECTION IN STEVENS-JOHNSON SYNDROME PATIENT WITH ORAL INVOLVEMENT: A CASE REPORT

Dentino : Jurnal Kedokteran Gigi ◽

10.20527/dentino.v6i1.10645 ◽

2021 ◽

Vol 6 (1) ◽

pp. 79

Author(s):

Etis Duhita Rahayuningtyas ◽

Indah Suasani Wahyuni ◽

Irna Sufiawati

Keyword(s):

Case Report ◽

Secondary Infection ◽

Severity Of Illness ◽

The Body ◽

Stevens Johnson Syndrome ◽

High Dose ◽

Oral Manifestation ◽

Secondary Infections ◽

Johnson Syndrome ◽

Oral Involvement

ABSTRACTBackground: Stevens-Johnson syndrome (SSJ) is a hypersensitivity reaction that is often triggered by drugs but this case is rare. These reactions result in uncontrolled keratinocyte damage to the skin and mucosa throughout the body, including the oral mucosa, and are often life-threatening. The use of high doses of corticosteroids is a treatment that is often given but it can trigger secondary infections of fungal and viral in the oral cavity. Purpose: This case report discusses the management of oral manifestations and secondary infections in SSJ patients, and becomes guidance for health professionals. Case: A-42-years-old male patient was consulted from the Department of Dermatology and Venereology (DV) due to oral pain and eating difficulties. The severity-of-illness-score for toxic-epidermal-necrolysis (SCORTEN) was 1. Erosive serosanguinous crusts, tend to bleed were found on the lips. Intraoral clinically presented wide erosive lesions and multiple ulcers, accompanied by a pseudomembranous plaque, and teeth decay. Hematologic examination showed an increase in leukocytes, neutrophil segments, monocytes, SGOT, urea, and creatinine as well as decreased hemoglobin, hematocrit, erythrocytes, MCHC, protein, and albumin. Anti-HSV1 IgG increased almost 6 times than normal values. The patient was diagnosed with SJS with oral involvement, secondary infections of pseudomembranous candidiasis, and herpetic stomatitis. Case Management: Systemic therapy given were intravenous dexamethasone, ranitidine, calcium, and cetirizine, from the DV Department, while hydrocortisone lip ointment, Chlorhexidine digluconate 0.12%, and Nystatin oral suspension for oral problems. The lesions progressed in 24 days. Conclusion: Oral secondary infections may occur in SJS patients due to high-dose corticosteroid therapy.Keywords: Herpetic Stomatitis, Oral Manifestation, Oral Secondary Infection, Pseudomembranous Candidiasis, Stevens-Johnson Syndrome.

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