scholarly journals O uso da suplementação materna para prevenção de defeitos congênitos e outros agravos na gestação / The use of maternal supplementation to prevent congenital defects and other aggregates in pregnancy

2021 ◽  
Vol 7 (6) ◽  
pp. 63883-63900
Author(s):  
Nathan Bardini Anhê ◽  
Leonardo Siqueira Aprile Pires ◽  
Marina Trevizan Guerra
2020 ◽  
Vol 10 (1) ◽  
pp. 470-475
Author(s):  
Zulliati Zulliati ◽  
Nita Hestiyana

 Latar Belakang: Anemia dalam kehamilan mempengaruhi lebih dari 500 juta wanita dalam masa kehamilan, yang nantinya dapat dikaitkan dengan gangguan pada ibu dan bayi. Suplementasi zat besi selama masa kehamilan diberikan secara terus menerus adalah alternatif yang menarik. Anemia sering terjadi akibat defisiensi zat besi dikarenakan pada ibu hamil terjadi peningkatan kebutuhan zat besi dua kali lipat akibat peningkatan volume darah tanpa ekspansi volume plasma, untuk memenuhi kebutuhan ibu (mencegah kehilangan darah pada saat melahirkan) dan pertumbuhan janin.Tujuan: Artikel ilmiah ini mencoba menelaah berdasarka studi literature hasil penelitian mengenai penggunaan tablet zat besi terhadap peningkatan berat badan lahir bayi.  Metode: Studi ini merupakan tinjauan literatur yang dilakukan dari tiga jurnal penelitian yang dilakukan di Viet Nam dan Spayol dan systematic review dari beberapa Randomized Controlled Trial yang dilakukan di cluster dan communityHasil: Beberapa penelitian menyebutkan terdapat korelasi yang erat antara anemia pada saat kehamilan dengan kematian janin, abortus, cacat bawaan, berat bayi lahir rendah, cadangan zat besi yang berkurang pada anak atau anak lahir dalam keadaan anemia gizi.Kesimpulan: Pemberian zat besi selama kehamilan selama ini diyakini  dapat mengatasi anemia dalam kehamilan untuk menghindari persalinan prematur dan perdarahan pada saat persalinan,Kata kunci :Berat badan lahir, zat besi ABSTRACT Background: Anemia in pregnancy affects more than 500 million women during pregnancy, which can later be associated with disorders of the mother and baby. Iron supplementation during pregnancy is given continuously is an attractive alternative. Anemia often occurs due to iron deficiency because in pregnant women there is a doubling of iron demand due to increased blood volume without plasma volume expansion, to meet the needs of the mother (preventing blood loss during childbirth) and fetal growth.Purpose: This scientific article tries to examine the literature based on the results of research on the use of iron tablets to increase infant birth weight.Methods: This study is a literature review conducted from three research journals conducted in Viet Nam and Spain and a systematic review of several Randomized Control Trials conducted in clusters and communities.Results: Several studies suggest that there is a close correlation between anemia during pregnancy and fetal death. , abortion, congenital defects, low birth weight, reduced iron reserves in children or children born in a state of nutritional anemia.Conclusion: The administration of iron during pregnancy is believed to be able to overcome anemia in pregnancy to avoid premature labor and bleeding during labor, Keywords: Birth weight, iron


1958 ◽  
Vol 12 (1) ◽  
pp. 1-7
Author(s):  
A. B. Hill ◽  
R. Doll ◽  
T. McL. Galloway ◽  
J. P. W. Hughes

2020 ◽  
pp. 44-45
Author(s):  
Amrit Gupta ◽  
Varuna Varma ◽  
Indrani Ghosh ◽  
Nirmal Kumar Gupta ◽  
Neeraj Kumar

Pregnancy is a prothrombotic stage, and in women with mechanical heart valves, anticoagulation is a challenge to attain an optimal outcome in mother and fetus. The use of combinations coumadin derivatives and various heparins is still in inconclusive stage due to various socioeconomic and demographic situation. In developing countries due to the cost of surgery, and compliance with lifelong anticoagulation there is contradiction for efficient outcome. Hence a safe protocol is necessary for implementation. Objectives: To evaluate the most effective, practical and uniform “Anticoagulation Regimen” suited to rural and semi-urban Indian pregnant women with mechanical heart valves with low socio-economic status and to observe its impact on the pregnancy outcomes. Methodology: Retrospective observational cohort study carried out at tertiary institute, between July 2006 to June 2015. 69 women became pregnant during the period from 2006 to 2015 on 1 or multiple occasions. 21(30.43%) pregnancies ended in early abortions and 46 (66.7%) pregnancies were continued. Anticoagulation protocol that was followed in these women was H-A-H protocol. These pregnancies were managed by obstetric team of tertiary care hospital under same consultant. Outcome measures were analyzed. Data was expressed as mean with standard deviation or frequency with percentage as appropriate. Results: Of 292 women, who underwent valve replacement surgery, 69 pregnancies were reported during this period on 1 or multiple occasions. 46 women had successful deliveries and rest 23 had single or multiple pregnancy failure. Incidence of stillbirth in those who delivered successfully was lower (2.89%). Fetal morbidity was 37.68% and none of the pregnant women had valve thrombosis. In 46 women majority had successful outcome except 6(13.04%) children out of 46 who developed anticoagulation related congenital defects. This was mainly seen in those women who presented late in pregnancy. Conclusion: Our Experience showed that Heparin-Acitrome-Heparin protocol is effective and safe in pregnancy than heparin alone, or acitrome alone regimen. The fetal outcome was good, maternal compliance was better and this protocol is widely recommended.


2012 ◽  
Vol 5 (3) ◽  
pp. 133-134 ◽  
Author(s):  
Jill Ward ◽  
Christopher Walker

In 2008 there were an estimated 259,000 people living in the USA with spinal cord injuries (SCI). The majority of these people are in their reproductive years, and over 19% are estimated to be women. Advances in medical management have allowed many women to live successfully with congenital defects or injuries resulting in SCI that even a few years ago would have been fatal. Although many of these women may be classified as ‘disabled’, fertility is not usually affected in SCI and many of these women desire children of their own. It is important to counsel these women regarding the range of issues related to pregnancy. These include conception issues, parenting with a disability, emotional concerns of the family, nutrition and exercise in pregnancy, risks in pregnancy, labour and delivery, postpartum care, and breastfeeding. For health-care providers it is important to know and understand your patient’s disability and be able to provide the best patient-centred quality care, understanding that each patient's circumstance may be unlike any other patient.


BMJ ◽  
1947 ◽  
Vol 1 (4506) ◽  
pp. 694-695 ◽  
Author(s):  
G. D. Pirrie

Author(s):  
Rajshree Dayanand Katke ◽  
Sivanandini Acharya ◽  
Soni Mourya

Mullerian duct anomalies (MDAs) are congenital defects of the female genital system that arise from abnormal embryological development of the Mullerian ducts. A didelphys uterus, also known as a “double uterus,” is one of the least common amongst MDAs. These abnormalities can include failure of development, fusion, canalization, or reabsorption, which normally occurs between 6 and 22 weeks in utero. Most sources estimate an incidence of these abnormalities to be from 0.5 to 5.0% in the general population. It is an observational study of cases of uterine didelphys with pregnancy over a period of 2 years. Uterus didelphys with pregnancy has variable maternal and perinatal outcome. First case presents an uneventful course in pregnancy which was terminated with caesarian section with a healthy baby. Second case presented to us with retained placenta with perforation of left horn which was managed by obstetric hysterectomy. The third case presents a didelphys uterus with a congenitally abnormal fetus with Hydrops fetalis with IUFD at 7th month of gestation terminated by caesarian section due to associated vertical vaginal septum. Pregnancy in a uterus Didelphys deserves early diagnosis of the anomaly, and meticulous care in pregnancy and delivery to avert the associated adverse outcomes.


2011 ◽  
Vol 2 (2) ◽  
pp. 105-110
Author(s):  
Shakila Nazir ◽  
Naeem H Naqvi ◽  
A Masood ◽  
N Naema

ABSTRACT Objective of the study Developmental defects of enamel may lead to esthetic tribulations. Malformed dental enamel is usually susceptible to caries and sensitivity of teeth. The objective of the present study was to evaluate the distribution of developmental defects affecting the enamel surfaces in the teeth of newborn babies of the mothers, caused by the use of lithium for a long time during pregnancy. Study design/methods The female rabbits were kept on this drug during pregnancy and their offsprings were used for the study. They were sacrificed to obtain their jaws. Teeth were extracted for assessment of the congenital defects developed during intrauterine life. Surface structure was studied by scanning electron microscopy and energy-dispersive X-ray microanalysis (SEM-EDX). Results The results showed that the drug had caused erosions of the incisors and the molars, as compared to the premolars. Conclusion According to the results, incisors and the molars appeared esthetically and functionally compromised teeth. The drug should, therefore, be used by doctor's prescription only, especially during pregnancy, avoiding the teratogenic effect on the dentition of the newborns.


Author(s):  
Sir Peter Gluckman ◽  
Mark Hanson ◽  
Chong Yap Seng ◽  
Anne Bardsley

Pregnancy is characterized by oxidative stress, wherein high metabolic demands are accompanied by heightened oxygen requirements in tissues. Additionally, a number of disorders of pregnancy are characterized by a reduction in antioxidant activity. Consequently, it has been hypothesized that maternal supplementation with antioxidants, particularly vitamins C and E, may be beneficial in preventing the occurrence of these disorders. Other important dietary antioxidants include carotenoids, and polyphenols (flavonoids). In general, studies of the effect of providing supplementary vitamin C and E to improve pregnancy outcomes have been inconsistent or have shown no positive effect; some evidence suggests high-dose vitamin E may be harmful. These and other antioxidants are necessary in pregnancy but should ideally be obtained from food sources.


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