scholarly journals Cost-Effectiveness of Interventions to Improve Maternal, Newborn and Child Health Outcomes: A WHO-CHOICE Analysis for Eastern Sub-Saharan Africa and South-East Asia

Author(s):  
Karin Stenberg ◽  
Rory Watts ◽  
Melanie Y. Bertram ◽  
Kaia Engesveen ◽  
Blerta Maliqi ◽  
...  

Background: Information on cost-effectiveness allows policy-makers to evaluate if they are using currently available resources effectively and efficiently. Our objective is to examine the cost-effectiveness of health interventions to improve maternal, newborn and child health (MNCH) outcomes, to provide global evidence relative to the context of two geographic regions. Methods: We consider interventions across the life course from adolescence to pregnancy and for children up to 5 years old. Interventions included are those that fall within the areas of immunization, child healthcare, nutrition, reproductive health, and maternal/newborn health, and for which it is possible to model impact on MNCH mortality outcomes using the Lives Saved Tool (LiST). Generalized cost-effectiveness analysis (GCEA) was used to derive average cost-effectiveness ratios (ACERs) for individual interventions and combinations (packages). Costs were assessed from the health system perspective and reported in international dollars. Health outcomes were estimated and reported as the gain in healthy life years (HLYs) due to the specific intervention or combination. The model was run for 2 regions: Eastern sub-Saharan Africa (SSA-E) and South-East Asia (SEA). Results: The World Health Organization (WHO) recommended interventions to improve MNCH are generally considered cost-effective, with the majority of interventions demonstrating ACERs below I$100/HLY saved in the chosen settings (low-and middle-income countries [LMICs]). Best performing interventions are consistent across the two regions, and include family planning, neonatal resuscitation, management of pneumonia and neonatal infection, vitamin A supplementation, and measles vaccine. ACERs below I$100 can be found across all delivery platforms, from community to hospital level. The combination of interventions into packages (such as antenatal care) produces favorable ACERs. Conclusion: Within each region there are interventions which represent very good value for money. There are opportunities to gear investments towards high-impact interventions and packages for MNCH outcomes. Cost-effectiveness tools can be used at national level to inform investment cases and overall priority setting processes.

2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Patrick Opiyo Owili ◽  
Miriam Adoyo Muga ◽  
Yiing-Jenq Chou ◽  
Yi-Hsin Elsa Hsu ◽  
Nicole Huang ◽  
...  

BMJ ◽  
2012 ◽  
Vol 344 (mar02 1) ◽  
pp. e612-e612 ◽  
Author(s):  
D. Chisholm ◽  
H. Naci ◽  
A. A. Hyder ◽  
N. T. Tran ◽  
M. Peden

2020 ◽  
Vol 5 (1) ◽  
pp. e002232 ◽  
Author(s):  
Cheikh Mbacké Faye ◽  
Fernando C Wehrmeister ◽  
Dessalegn Y Melesse ◽  
Martin Kavao Kavao Mutua ◽  
Abdoulaye Maïga ◽  
...  

Subnational inequalities have received limited attention in the monitoring of progress towards national and global health targets during the past two decades. Yet, such data are often a critical basis for health planning and monitoring in countries, in support of efforts to reach all with essential interventions. Household surveys provide a rich basis for interventions coverage indicators on reproductive, maternal, newborn and child health (RMNCH) at the country first administrative level (regions or provinces). In this paper, we show the large subnational inequalities that exist in RMNCH coverage within 39 countries in sub-Saharan Africa, using a composite coverage index which has been used extensively by Countdown to 2030 for Women’s, Children’s and Adolescent’s Health. The analyses show the wide range of subnational inequality patterns such as low overall national coverage with very large top inequality involving the capital city, intermediate national coverage with bottom inequality in disadvantaged regions, and high coverage in all regions with little inequality. Even though nearly half of the 34 countries with surveys around 2004 and again around 2015 appear to have been successful in reducing subnational inequalities in RMNCH coverage, the general picture shows persistence of large inequalities between subnational units within many countries. Poor governance and conflict settings were identified as potential contributing factors. Major efforts to reduce within-country inequalities are required to reach all women and children with essential interventions.


BMJ ◽  
2012 ◽  
Vol 344 (mar02 2) ◽  
pp. e614-e614 ◽  
Author(s):  
G. M. Ginsberg ◽  
J. A. Lauer ◽  
S. Zelle ◽  
S. Baeten ◽  
R. Baltussen

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