scholarly journals Conversion of Human Hepatoma Cells by 520d-5p to Benign or Normal Liver Tissues via a stemness-Mediated Process

Oncogen ◽  
2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Satoshi Tsuno ◽  
Xinhui Wang ◽  
Kohei Shomori ◽  
Keigo Miura ◽  
Yugo Miura ◽  
...  
Keyword(s):  
Normal Liver ◽  
Hepatoma Cells ◽  
Human Hepatoma ◽  
Human Hepatoma Cells ◽  
Liver Tissues

HAb18G/CD147 enhances cell proliferation by promoting G0/G1 to S transition by ERK1/2 dependent cyclin D1 synthesis in human hepatoma cells

2010 ◽  
Vol 34 (8) ◽  
pp. S45-S45
Author(s):  
Yunshan Guo ◽  
Juan Tang ◽  
Zhinan Chenand Jianli Jiang
Keyword(s):  
Cell Proliferation ◽  
Cyclin D1 ◽  
Hepatoma Cells ◽  
Human Hepatoma ◽  
Human Hepatoma Cells

Apoptotic Effects of Dichloro Stearic and Dichloro Myristic Acid in Human Hepatoma Cells (HepG2)

2001 ◽  
Vol 89 (2) ◽  
pp. 85-91 ◽  
Author(s):  
Einar Lystad ◽  
Arne T. Hostmark ◽  
Einar Jebens
Keyword(s):  
Myristic Acid ◽  
Hepatoma Cells ◽  
Human Hepatoma ◽  
Human Hepatoma Cells ◽  
Apoptotic Effects

Monoterpene indole alkaloids from the leaves of Tabernaemontana elegans induce apoptosis activity in human hepatoma cells

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
TA Mansoor ◽  
RM Ramalho ◽  
CMP Rodrigues ◽  
S Mulhovo ◽  
MJU Ferreira
Keyword(s):  
Indole Alkaloids ◽  
Hepatoma Cells ◽  
Human Hepatoma ◽  
Human Hepatoma Cells ◽  
Monoterpene Indole Alkaloids

Primary but not secondary biliary acids inhibit hepatitis D virus entry into human hepatoma cells expressing the sodium-taurocholate cotransporting polypeptide

2014 ◽  
Vol 52 (01) ◽  
Author(s):  
IVA Pereira ◽  
M Wilson ◽  
C Sarrazin ◽  
CPMS de Oliveira ◽  
MP Manns ◽  
...  
Keyword(s):  
Virus Entry ◽  
Sodium Taurocholate ◽  
Hepatoma Cells ◽  
Human Hepatoma ◽  
Human Hepatoma Cells ◽  
Hepatitis D ◽  
Hepatitis D Virus ◽  
Biliary Acids

The KLF6 Super Enhancer Modulates Cell Proliferation via MiR-1301 in Human Hepatoma Cells

MicroRNA ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 64-69 ◽  
Author(s):  
KumChol Ri ◽  
Chol Kim ◽  
CholJin Pak ◽  
PhyongChol Ri ◽  
HyonChol Om
Keyword(s):  
Cell Proliferation ◽  
Cellular Proliferation ◽  
Hepatoma Cells ◽  
Regulation Mechanism ◽  
Dependent Manner ◽  
Human Hepatoma ◽  
Human Hepatoma Cells ◽  
Over Expression ◽  
Super Enhancer ◽  
Engineering Changes

Background: Recent studies have attempted to elucidate the function of super enhancers by means of microRNAs. Although the functional outcomes of miR-1301 have become clearer, the pathways that regulate the expressions of miR-1301 remain unclear. Objective: The objective of this paper was to consider the pathway regulating expression of miR- 1301 and miR-1301 signaling pathways with the inhibition of cell proliferation. Methods: In this study, we prepared the cell clones that the KLF6 super enhancer was deleted by means of the CRISPR/Cas9 system-mediated genetic engineering. Changes in miR-1301 expression after the deletion of the KLF6 super enhancer were evaluated by RT-PCR analysis, and the signal pathway of miR-1301 with inhibition of the cell proliferation was examined using RNA interference technology. Results: The results showed that miR-1301 expression was significantly increased after the deletion of the KLF6 super enhancer. Over-expression of miR-1301 induced by deletion of the KLF6 super enhancer also regulated the expression of p21 and p53 in human hepatoma cells. functional modeling of findings using siRNA specific to miR-1301 showed that expression level changes had direct biological effects on cellular proliferation in Human hepatoma cells. Furthermore, cellular proliferation assay was shown to be directly associated with miR-1301 levels. Conclusion: As a result, it was demonstrated that the over-expression of miR-1301 induced by the disruption of the KLF6 super enhancer leads to a significant inhibition of proliferation in HepG2 cells. Moreover, it was demonstrated that the KLF6 super enhancer regulates the cell-proliferative effects which are mediated, at least in part, by the induction of p21and p53 in a p53-dependent manner. Our results provide the functional significance of miR-1301 in understanding the transcriptional regulation mechanism of the KLF6 super enhancer.

(−)-Epigallocatechin-3-gallate Induces Apoptosis of Human Hepatoma Cells by Mitochondrial Pathways Related to Reactive Oxygen Species

2009 ◽  
Vol 57 (15) ◽  
pp. 6685-6691 ◽  
Author(s):  
WenJuan Li ◽  
ShaoPing Nie ◽  
Qiang Yu ◽  
MingYong Xie
Keyword(s):  
Reactive Oxygen Species ◽  
Reactive Oxygen ◽  
Hepatoma Cells ◽  
Oxygen Species ◽  
Human Hepatoma ◽  
Human Hepatoma Cells

scholarly journals Insulin suppresses hepatitis B surface antigen expression in human hepatoma cells

1989 ◽  
Vol 264 (26) ◽  
pp. 15304-15308
Author(s):  
C K Chou ◽  
T S Su ◽  
C M Chang ◽  
C P Hu ◽  
M Y Huang ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Surface Antigen ◽  
Hepatitis B Surface Antigen ◽  
Antigen Expression ◽  
Hepatoma Cells ◽  
Human Hepatoma ◽  
Human Hepatoma Cells ◽  
Surface Antigen Expression
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