Hubungan kelahiran prematur dengan penyakit jantung bawaan di RSUP Prof. Dr. R.D. Kandou Manado periode tahun 2013-2014

Abstract: Preterm birth is all births before 37 completed weeks of gestation since the first day of a woman's last menstrual period. In the maturation of all organs of preterm birth has not been achieved so well that it may cause disruption, one of them is called the heart of congenital heart disease. Congenital heart disease is a problem with the heart's structure and function that is present at birth. The study aimed is to examine the relationship between preterm birth with congenital heart disease. This studied was conducted using observational analytic study design with a retrospective approach. The studied sample was children who were born Preterm in the Section of Child Health Prof. Dr R. D Kandou Manado diagnosed with congenital heart disease in 2013-2014. The study population numbered 353 children born prematurely, the sample fulfilled inclusion criteria are children born prematurely with CHD totaling 35 samples, and 30 samples were taken comparators. The assay used in this study is the Fisher Exact Test, produces a value p = 0.011 <α = 0.05, which indicates there is a significant relationship between preterm birth with congenital heart disease. Conclusion: There was a significant relationship between preterm birth with congenital heart disease.Keywords: Preterm birth, congenital heart diseaseAbstrak: Kelahiran prematur adalah semua kelahiran sebelum 37 minggu masa kehamilan sejak hari pertama haid terakhir seorang wanita. Pada kelahiran prematur kematangan semua organ belum tercapai dengan baik sehingga dapat menyebabkan gangguan, salah satu diantaranya yaitu jantung yang disebut PJB. Penyakit jantung bawaan (PJB) sendiri adalah permasalahan pada struktur jantung yang tampak setelah kelahiran. Tujuan penelititan ini adalah mengetahui hubungan antara kelahiran prematur dengan penyakit jantung bawaan. Penelitian ini dilakukan dengan menggunakan desain penelitian analitik observasional dengan pendekatan retrospektif. Sampel penelitian yaitu anak yang lahir prematur di Bagian Ilmu Kesehatan Anak RSUP Prof. Dr. R. D. Kandou Manado yang terdiagnosis PJB pada tahun 2013-2014. Populasi penelitian berjumlah 353 anak yang lahir prematur, sampel penelitian yang memenuhi kriteria inklusi yaitu anak yang lahir prematur dengan PJB berjumlah 35 sampel, dan diambil 30 sampel pembanding . Uji yang digunakan pada penelitian ini adalah Uji Fisher Exact, menghasilkan nilai p = 0,011 < α = 0,05, yang menunjukan ada hubungan yang bermakna antara kelahiran prematur dengan PJB. Simpulan: Ada hubungan yang bermakna antara kelahiran prematur dengan PJB.Kata kunci: Kelahiran prematur, PJB

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Congenital heart disease, socioeconomic position and risk of preterm birth

Revue d Épidémiologie et de Santé Publique ◽

10.1016/j.respe.2018.05.009 ◽

2018 ◽

Vol 66 ◽

pp. S234

Author(s):

S. Kloster ◽

J. Tolstrup ◽

A. Ersbøll

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Preterm Birth ◽

Socioeconomic Position ◽

Congenital Heart

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OP15.05: Risk of spontaneous and iatrogenic preterm birth in pregnancies with prenatal diagnosis of major congenital heart disease

Ultrasound in Obstetrics and Gynecology ◽

10.1002/uog.20797 ◽

2019 ◽

Vol 54 (S1) ◽

pp. 134-135

Author(s):

V. Giorgione ◽

V. Fesslova ◽

S. Boveri ◽

M. Candiani ◽

A. Khalil ◽

...

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Preterm Birth ◽

Prenatal Diagnosis ◽

Congenital Heart

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Anatomy and function of the heart and intrathoracic vessels in congenital heart disease: Evaluation with the dynamic spatial reconstructor

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(85)80146-7 ◽

1985 ◽

Vol 5 (1) ◽

pp. 70S-76S ◽

Cited By ~ 7

Author(s):

Lawrence J. Sinak ◽

Yun-He Liu ◽

Michael Block ◽

Douglas D. Mair ◽

Paul R. Julsrud ◽

...

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Congenital Heart ◽

And Function

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Diagnosis and Management of Lymphatic Disorders in Congenital Heart Disease

Current Cardiology Reports ◽

10.1007/s11886-020-01405-y ◽

2020 ◽

Vol 22 (12) ◽

Author(s):

Benjamin Kelly ◽

Sheyanth Mohanakumar ◽

Vibeke Elisabeth Hjortdal

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Congenital Heart ◽

Treatment Options ◽

Future Research ◽

Protein Losing Enteropathy ◽

Current Review ◽

Lymphatic Complications ◽

And Function ◽

Lymphatic Imaging

Abstract Purpose of Review Lymphatic disorders have received an increasing amount of attention over the last decade. Sparked primarily by improved imaging modalities and the dawn of lymphatic interventions, understanding, diagnostics, and treatment of lymphatic complications have undergone considerable improvements. Thus, the current review aims to summarize understanding, diagnostics, and treatment of lymphatic complications in individuals with congenital heart disease. Recent Findings The altered hemodynamics of individuals with congenital heart disease has been found to profoundly affect morphology and function of the lymphatic system, rendering this population especially prone to the development of lymphatic complications such as chylous and serous effusions, protein-losing enteropathy and plastic bronchitis. Summary Although improved, a full understanding of the pathophysiology and targeted treatment for lymphatic complications is still wanting. Future research into pharmacological improvement of lymphatic function and continued implementation of lymphatic imaging and interventions may improve knowledge, treatment options, and outcome for affected individuals.

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P879 3D transoesophageal echocardiography to asses a case of a non-ebstein tricuspid valve congenital regurgitation

European Heart Journal - Cardiovascular Imaging ◽

10.1093/ehjci/jez319.521 ◽

2020 ◽

Vol 21 (Supplement_1) ◽

Author(s):

I Sanz Ortega ◽

S Velasco Del Castillo ◽

J J Onaindia Gandarias ◽

I Rodriguez Sanchez ◽

J Florido Perena ◽

...

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Tricuspid Valve ◽

Tricuspid Regurgitation ◽

Congenital Heart ◽

Volume Overload ◽

Transoesophageal Echocardiography ◽

Ebstein Anomaly ◽

Downward Displacement ◽

And Function

Abstract Introduction Due to the complexity of congenital heart disease and limitations of transthorathic echocardiogram (TTE), especially in adult patients, it is not unusual to need other image techniques to assess cardiac anatomy and function. The most common primary anomaly of tricuspid valve (TV) is Ebstein anomaly, but there are other much rarer primary anomalies of this valve consisting in prolapse, cord retraction.... without downward displacement of the leaflet, generally causing tricuspid regurgitation (TR) that can be severe and sometimes intervention is needed, preferably reparation. Due to anatomical issues, it is difficult to assess anatomy of TV in TTE, so sometimes 3D-TTE must be performed to clarify the mechanism and to measure orifice, but when transthoracic view is not enough, 3D transoesophageal echocardiogram (TOE) can be useful for this purpose. Case We report the case of a 15-year-old boy that was referred to our clinic because of shortness of breath and a systolic tricuspid murmur. TTE was performed and an image compatible with tricuspid valve prolapse with no apical displacement of any leaflets (Figure, A) causing severe TR (Figure, B) was noticed, as well as severely dilated right chambers, with good ejection fraction of both ventricles. It was not clear the mechanism so 2D TOE was done, showing a prolapse of a leaflet (Figure, C) causing severe TR (Figure, D). The mechanism was finally clarified by 3D TOE (figure E). This was a prolapse of lateral portion of posterior leaflet (asterisk) with restrictive movement of anterior (triangle) and septal (arrow) ones, causing a huge coaptation defect in systole leading to a very severe tricuspid insufficiency with signs of volume overload of right ventricle. There was no atrial septal defect and pulmonary drainage anomalies were ruled out by cardiac magnetic resonance. Patient was referred to surgery due to symptoms and great dilatation of right chambers. Conclusión: Due to anatomical complexity and limitations of echography, cross and multimodality cardiac imaging is usually needed in assessing congenital heart disease. Apart from Ebstein anomaly, other congenital entities of tricuspid valve such as prolapse and/or retraction can lead to severe tricuspid regurgitation. Due to limitations of 2D TTE in assessing tricuspid valve anatomy, 3D TTE has to be performed, but if it is not enough, 3D TOE can be an option to evaluate mechanism and directly see the orifice of regurgitation in congenital disease of tricuspid valve. Abstract P879 Figure

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Outcomes and Prognostic Factors for Adult Patients With Congenital Heart Disease Undergoing Primary or Reoperative Systemic Atrioventricular Valve Surgery

World Journal for Pediatric and Congenital Heart Surgery ◽

10.1177/2150135117692974 ◽

2017 ◽

Vol 8 (3) ◽

pp. 346-353

Author(s):

Elizabeth H. Stephens ◽

Jiho Han ◽

Jonathan Ginns ◽

Marlon Rosenbaum ◽

Paul Chai ◽

...

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Prognostic Factors ◽

Adverse Events ◽

Congenital Heart ◽

Atrioventricular Septal Defect ◽

The Other ◽

Mitral Valve Stenosis ◽

Atrioventricular Valve ◽

Exact Test

Background: Adults with congenital heart disease (ACHD) undergoing systemic atrioventricular valve (SAVV) surgery are a complex, understudied population. We assessed midterm outcomes and prognostic factors in ACHD undergoing SAVV surgery. Methods: We performed retrospective evaluation of ACHD undergoing SAVV surgery from January 2005 to February 2016: 14 (33%) patients with congenital mitral valve stenosis/regurgitation, 15 (35%) with atrioventricular septal defect (AVSD), and 14 (33%) with congenitally corrected transposition of the great arteries (ccTGA) with systemic tricuspid valve regurgitation. Adverse events were defined as mortality, reoperation on SAVV, and late more-than-moderate (> moderate) SAVV regurgitation. Statistical analysis was performed using Fisher’s exact test and one-way analysis of variance as well as univariate and multivariate risk factor analysis. Results: Fifteen (35%) patients had preoperative systemic ventricular dysfunction, including 13 patients with ccTGA (93%, P < .001). Twenty-three (54%) patients underwent valve repair, 20 (47%) patients underwent replacement, and 20 (47%) patients underwent an associated procedure. Replacement was higher in patients with ccTGA (86%) than the other groups ( P < 0.01). Thirty-seven patients (91% of survivors) were free of significant SAVV regurgitation at last follow-up, with patients with AVSD having greater regurgitation grades compared to the other groups ( P < 0.01). In-hospital mortality, late mortality, late > moderate SAVV regurgitation, and SAVV reoperation rates were 5% (n = 2), 2% (n = 1), 9% (n = 3), and 7% (n = 3), respectively. On multivariate analysis, predischarge SAVV regurgitation grade was the only significant predictor of adverse events (odds ratio = 8.2, 95% confidence interval: 1.1-63.8, P = .045). Conclusion: Overall outcomes in this challenging population are good. The single factor associated with adverse events was predischarge SAVV regurgitation grade.

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