scholarly journals Review Artikel : Aktivitas Antikanker dari Spons Laut Genus Xestospongia

2021 ◽  
Vol 4 (1) ◽  
pp. 11
Author(s):  
Adryan Fristiohady,Prahedi Setya Ibrahim Asniar Pascayantri

Abstract            The discovery of novel agents in the treatment of cancer is still being conducted, one of them is by developing the marine natural resources as an anti-cancer drug. Sponges like the genus Xestospongia, are natural marine resources that have potential as anti-cancer. Thus,, this review aims to showing the potential of the genus Xestospongia as an anticancer. This review was carried out by collecting the literature from various databases from 2014 to 2019. Results obtained that marin sponge Xestospongia, including Xestospongia testudinaria, Xestospongia exigua, Xestospongia muta and Xestospongiawiedemayeri, were used as anticancer. These compounds such as Quinolizidine, Aragusterol, Araguspic and many more.Keywords— Xestospongia, anticancer, cytotoxicity Abstrak            Penemuan obat baru dalam pengobatan kanker masih intensif dilakukan, salah satunya dengan pengembangan sumber daya alam laut sebagai obat anti kanker. Spons seperti genus Xestospongia, merupakan sumber daya alam laut yang memiliki potensi sebagai anti kanker. Oleh karena itu, review ini bertujuan untuk menunjukkan potensispons genus Xestospongia sebagai antikanker. Review ini dilakukan dengan mengumpulkan pustaka dari berbagai database dari tahun 2014 hingga 2019. Hasil yang didapatkan bahwa spesies dari Xestospongia seperti Xestospongia testudinaria, Xestospongia exigua, Xestospongia muta dan Xestospongia wiedemayeri tercatat berpotensi sebagai antikanker. Senyawa-senyawa tersebut seperti Quinolizidine, Aragusterol, Araguspic dan masih banyak lagi.Kata Kunci— Xestospongia, antikanker, sitotoksisitas 

Xenobiotica ◽  
2009 ◽  
Vol 00 (00) ◽  
pp. 090901052053001-8
Author(s):  
K. Murai ◽  
H. Yamazaki ◽  
K. Nakagawa ◽  
R. Kawai ◽  
T. Kamataki

2010 ◽  
Author(s):  
N. Magnavita ◽  
I. lavicoli ◽  
V. Leso ◽  
A. Bergamaschi

Author(s):  
Pavan C ◽  
Madhavi BLR

Nanocomposites are substances that incorporate nanoparticles (0.5-5% by weight) into a matrix of standard material, which enhances the mechanical strength, toughness including thermal or electrical conductivity and other properties. Nanocomposites are versatile in terms of their applications such as anti-corrosive, healing of bones, sensors, environmental protection, packaging, wastewater treatment, and diagnosis of tumors and other diverse uses. They may be fabricated by blending nanofillers with a polymer to produce a composite. The current trend of processing is by polymerizing monomers. Nanocomposites serve as sustainable solutions to curb global issues. Evaluation is performed on properties such as mechanical, thermal, dispersion, and toxicological. Some marketed products of nanocomposites include In Mat (coating), FiltekZ350 XT by 3M (tooth fillers), chitosan/organic rectorite nanocomposite films (bactericidal activity), graphene oxide/Carboxymethylcellulose (targeted drug delivery of anti-cancer drug doxorubicin), MD1 Flex, Nano Clean MD1, Plactive TM (Antimicrobial nanocomposites) and NovaProTM(Tooth fillers). This article discusses about Nanocomposites–their types, preparation methods, recent research and applications.


Author(s):  
Sally Sabra ◽  
Mona Abdelmoneem ◽  
Mahmoud Abdelwakil ◽  
Moustafa Taha Mabrouk ◽  
Doaa Anwar ◽  
...  

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