scholarly journals Cardio-Pulmonary Physiology during Yoga Inversion Practice

2020 ◽  
Author(s):  
Paula Seffens ◽  
William Seffens
Keyword(s):  
Heart Failure ◽  
Whole Body ◽  
Physiological Changes ◽  
O2 Consumption ◽  
Brachial Blood Pressure ◽  
Warm Up ◽  
Heart Failure Patients ◽  
Pulmonary Physiology ◽  
Sufficient Cause ◽  
Preliminary Study

Introduction: Mass media advertisements have claimed health benefits of body inversion for relaxation and cardiovascular conditioning. We conducted a preliminary study to evaluate real time physiological changes and responses to mediation, Hatha yoga, and specifically inversion and standing postures to determine the O2 consumption recorded by a wearable metabolic device and cardiovascular measures. Methods: Healthy study volunteers executed a sequence of yoga postures that included inversions of whole body while wearing a Cosmed K5 portable metabolic backpack. We obtained brachial blood pressure during the last 30 seconds of each posture. Each trial began seated, followed by a warm-up consisting of gentle flow yoga and ending with relaxation. Results: Twelve experienced yoga practitioners (mean age 44 years, 58% female) participated in 17 trials. Over all trials, mean VO2 for Sirsasana as compared with the supported inversion posture decreased from 8.4 to 4.9 (ml/kg/min). Conclusions: Conflicting findings exist in the literature concerning inversion physiology. Cardiac output response to inversion is not consistent in scientific reports. Participants responded differently under a variety of circumstances in previous studies, making comparisons to this and existing research challenging. We find sufficient cause for further research and suggest that some forms of inversion may be beneficial to heart failure patients. Keywords: yoga, inversion, cardiopulmonary, heart failure, physiology

Hematocrit-Related Alterations of Circulating microRNA-21 Levels in Heart Failure Patients with Reduced Ejection Fraction: A Preliminary Study

2021 ◽  
Vol 25 (4) ◽  
pp. 302-306
Author(s):  
Viera Nemcekova ◽  
Zuzana Kmecova ◽  
Lenka Bies Pivackova ◽  
Eva Goncalvesova ◽  
Peter Krenek ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Circulating Microrna ◽  
Reduced Ejection Fraction ◽  
Heart Failure Patients ◽  
Preliminary Study

scholarly journals Correlation between Insulin Resistance and LVEF in non Diabetic Chronic Heart Failure Patients admitted in a Tertiary Care Hospital

2021 ◽  
Vol 17 (2) ◽  
pp. 99-102
Author(s):  
Md Azharul Islam ◽  
Manzoor Mahmood ◽  
Khurshed Ahmed ◽  
Sajal Krishna Banerjee ◽  
Syed Ali Ahsan ◽  
...  
Keyword(s):  
Heart Failure ◽  
Insulin Resistance ◽  
Insulin Sensitivity ◽  
Chronic Heart Failure ◽  
Negative Correlation ◽  
Whole Body ◽  
Model Assessment ◽  
Care Hospital ◽  
Heart Failure Patients ◽  
Study Results

Background: Insulin resistance is a well-established composite index of systemic inflammatory and metabolic disorders. A wide variety of methods like, HOMA-IR (Homeostatic model assessment insulin resistance), FGIR (Fasting glucose insulin ratio), ISI-Composite (an index of whole body insulin sensitivity), QUICKI (quantitative insulin sensitivity check index) etc are available for assessing IR. Objective: To find out the correlation between insulin resistance and LVEF in non diabetic chronic heart failure patients. Methodology: This cross sectional study was carried out in the Department of Cardiology in Bangabandhu Sheikh Mujib Medical University, Shahbagh, Dhaka from February, 2019 to June, 2020. Patients admitted with chronic heart failure with reduced ejection fraction were included in this study. Patients with diabetic, prediabetic and patient who did not give written informed consent were excluded in this study. Results: LVEF 25-29% was 16 patients out of which 10(66.7%) had significant insulin resistance. LVEF 30- 34% was found in 28 patients, among them 16(41.0%) had no insulin resistance. LVEF 35-39% was found in 19 patients out of which 18(46.2%) had no insulin resistance. The difference was statistically significant (p<0.05). A negative correlation (r=-0.340; p=0.006) was found between insulin resistance and LVEF. Conclusion: Majority non diabetic chronic heart failure patients had no insulin resistance. Significant negative correlation was found between insulin resistance and LVEF. University Heart Journal Vol. 17, No. 2, Jul 2021; 99-102

Metabolic Effects of Short-term GLP-1 Treatment in Insulin Resistant Heart Failure Patients

2012 ◽  
Vol 120 (05) ◽  
pp. 266-272 ◽  
Author(s):  
R. Nielsen ◽  
H. Wiggers ◽  
M. Halbirk ◽  
H. Bøtker ◽  
J. Holst ◽  
...  
Keyword(s):  
Heart Failure ◽  
Insulin Sensitivity ◽  
Glucose Tolerance ◽  
University Hospital ◽  
Metabolic Effects ◽  
Whole Body ◽  
Body Protein ◽  
Heart Failure Patients ◽  
Insulin Resistant ◽  
Glucose Levels

AbstractWe studied the metabolic effects of 48-h GLP-1 treatment in insulin resistant heart failure patients.In a randomized placebo-controlled double-blinded cross-over study, 11 non-diabetic HF patients with IHD received 48-h GLP-1 and placebo-infusion. We applied OGTT, hyperinsulinemic clamp, indirect calorimetry, forearm, and tracer methods.7 insulin resistant HF (EF 28%±2) patients completed the protocol. GLP-1 decreased plasma glucose levels (p=0.048) and improved glucose tolerance. 4 patients had hypoglycemic events during GLP-1 vs. none during placebo. GLP-1 treatment tended to increase whole body protein turnover (p=0.08) but did not cause muscle wasting. No significant changes in circulating levels of insulin, glucagon, free fatty acids or insulin sensitivity were detected.GLP-1 treatment decreased glucose levels and increased glucose tolerance in insulin resistant HF patients with IHD. Hypoglycemia was common and may limit the use of GLP-1 in these patients. Insulin sensitivity, lipid-, and protein metabolism remained unchanged.Data were collected at the examinational laboratories of Department of Endocrinology and Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark

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